PA8620301A1 - Inhibidores heterociclil amino de 11-beta-hidrosiesteroide deshidrogenasa tipo 1 - Google Patents

Inhibidores heterociclil amino de 11-beta-hidrosiesteroide deshidrogenasa tipo 1

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Publication number
PA8620301A1
PA8620301A1 PA20048620301A PA8620301A PA8620301A1 PA 8620301 A1 PA8620301 A1 PA 8620301A1 PA 20048620301 A PA20048620301 A PA 20048620301A PA 8620301 A PA8620301 A PA 8620301A PA 8620301 A1 PA8620301 A1 PA 8620301A1
Authority
PA
Panama
Prior art keywords
hydrosiesteroid
beta
dehydrogenase type
inhibitors amino
formula
Prior art date
Application number
PA20048620301A
Other languages
English (en)
Inventor
Stephan James Cripps
Martin Paul Edwards
Theodore O Johnson Jr
Christopher Ronald Smith
Sajiv Krishnan Nair
Michael Siu
Wendy Dianne Taylor
Yong Wang
Hengmiao Cheng
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PA8620301A1 publication Critical patent/PA8620301A1/es

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    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

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Abstract

LA PRESENTE INVENCION SE REFIERE A LOS COMPUESTOS CON LA FORMULA (1), O A UNA SAL DE ESTOS ACEPTABLE DESDE UN PUNTO DE VISTA FARMACEUTICO: LA INVENCION TAMBIEN SE REFIERE A COMPOSICIONES FARMACEUTICAS QUE COMPRENDEN LOS COMPUESTOS DE FORMULA (1) Y A METODOS PARA TRATAR UNA CONDICION QUE ESTA MEDIADA POR LA MODULACION DE 11-B-HSD-1, METODO QUE COMPRENDE ADMINISTRAR A UN MAMIFERO UNA CANTIDAD EFICAZ DE UN COMPUESTO DE FORMULA (1).
PA20048620301A 2003-12-19 2004-12-17 Inhibidores heterociclil amino de 11-beta-hidrosiesteroide deshidrogenasa tipo 1 PA8620301A1 (es)

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IL175949A0 (en) 2006-10-05
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US20050148631A1 (en) 2005-07-07
JP2007514731A (ja) 2007-06-07
MXPA06007077A (es) 2006-08-23
EA200600990A1 (ru) 2006-10-27
NL1027811C2 (nl) 2006-03-06
WO2005060963A1 (en) 2005-07-07
MA28271A1 (fr) 2006-11-01
TW200530185A (en) 2005-09-16
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WO2005060963A8 (en) 2005-12-01
NL1027811A1 (nl) 2005-06-21
AP2006003633A0 (en) 2006-06-30
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ECSP066653A (es) 2006-10-25
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NO20063298L (no) 2006-09-14
PE20050864A1 (es) 2005-10-31

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