PA8486701A1 - Antagonistas de 5ht1 para terapia antidepresiva - Google Patents
Antagonistas de 5ht1 para terapia antidepresivaInfo
- Publication number
- PA8486701A1 PA8486701A1 PA19998486701A PA8486701A PA8486701A1 PA 8486701 A1 PA8486701 A1 PA 8486701A1 PA 19998486701 A PA19998486701 A PA 19998486701A PA 8486701 A PA8486701 A PA 8486701A PA 8486701 A1 PA8486701 A1 PA 8486701A1
- Authority
- PA
- Panama
- Prior art keywords
- antagonists
- antidepressive
- therapy
- antidepressive therapy
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Reproductive Health (AREA)
- Psychology (AREA)
- Diabetes (AREA)
- Addiction (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Gynecology & Obstetrics (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A COMPUESTOS DE LA FORMULA 1, EN LA QUE R1,R2,R3 Y R4 SE DEFINEN COMO EN LA MEMORIA DESCRIPTIVA. ESTOS COMPUESTOS SON UTILES COMO AGENTES PSICOTERAPEUTICOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11395798P | 1998-12-28 | 1998-12-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
PA8486701A1 true PA8486701A1 (es) | 2000-09-29 |
Family
ID=22352526
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PA19998486701A PA8486701A1 (es) | 1998-12-28 | 1999-12-07 | Antagonistas de 5ht1 para terapia antidepresiva |
Country Status (43)
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003065970A2 (en) * | 2001-02-20 | 2003-08-14 | Royal College Of Surgeons Ie | Treatment of fibromyalgia and related fatigue syndromes using pindolol |
GB0203778D0 (en) * | 2002-02-18 | 2002-04-03 | Glaxo Group Ltd | Compounds |
AU2004220327B2 (en) * | 2003-03-12 | 2010-06-24 | Pfizer Products Inc. | Pyridyloxymethyl and benzisoxazole azabicyclic derivatives |
GB0316915D0 (en) * | 2003-07-18 | 2003-08-20 | Glaxo Group Ltd | Compounds |
JP2007519705A (ja) * | 2004-01-29 | 2007-07-19 | ファイザー・プロダクツ・インク | Cns障害を治療するための非定型抗精神病薬とアミノメチルピリジルオキシメチル/ベンゾイソオキサゾールアザビシクロ誘導体の組合せ |
AR049478A1 (es) | 2004-03-25 | 2006-08-09 | Solvay Pharm Bv | Un procedimiento para la preparacion de 3-amino-8-(1-piperazinil)-2h-1-benzopiran-2-ona. sales e hidratos y composiciones farmaceuticas. |
AR048112A1 (es) * | 2004-03-25 | 2006-03-29 | Solvay Pharm Bv | Derivados de 1-(2h-1-benzopiran-2-on-8-il)-piperazina para el tratamiento de dolor |
JP2008512440A (ja) * | 2004-09-10 | 2008-04-24 | ファイザー・プロダクツ・インク | ジアザビシクロ化合物含有ベンゾイソオキサゾールを用いる気分障害の治療方法 |
US20070270430A1 (en) * | 2004-09-10 | 2007-11-22 | Pfzer Inc | Methods of Treating Cognitive Disorders Using Pyridyloxymethyl and Benzisoxazole Azabicyclic Derivatives |
DE102005026194A1 (de) * | 2005-06-06 | 2006-12-07 | Grünenthal GmbH | Substituierte N-Benzo[d]isoxazol-3-yl-amin-Derivate und deren Verwendung zur Herstellung von Arzneimitteln |
WO2008019431A1 (en) * | 2006-08-14 | 2008-02-21 | Brc Operations Pty Limited | Method and compositions for simultaneously regulating memory and mood |
US10154988B2 (en) | 2012-11-14 | 2018-12-18 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
WO2020183011A1 (en) | 2019-03-14 | 2020-09-17 | Institut Curie | Htr1d inhibitors and uses thereof in the treatment of cancer |
US20230057844A1 (en) * | 2019-12-20 | 2023-02-23 | The Jackson Laboratory | Molecular targets for addiction |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5157034A (en) * | 1991-02-27 | 1992-10-20 | Pfizer Inc. | Neuroleptic perhydro-1H-pyrido[1,2-a]pyrazines |
GB9410512D0 (en) * | 1994-05-25 | 1994-07-13 | Smithkline Beecham Plc | Novel treatment |
US5756496A (en) * | 1994-05-28 | 1998-05-26 | Smithkline Beecham P.L.C. | Amide derivatives having 5HT1D-antagonist activity |
WO1998050358A1 (en) * | 1997-04-18 | 1998-11-12 | Smithkline Beecham Plc | Indole derivatives having combined 5ht1a, 5ht1b and 5ht1d receptor antagonist activity |
IT1293807B1 (it) * | 1997-08-01 | 1999-03-10 | Recordati Chem Pharm | Derivati 1- (n-fenilaminoalchil) piperazinici sostituiti alla posizione 2 dell'anello fenilico |
PA8469101A1 (es) * | 1998-04-09 | 2000-09-29 | Pfizer Prod Inc | Ligandos azabiciclicos de receptores 5ht1 |
-
1999
- 1999-03-11 UA UA2001064492A patent/UA62015C2/uk unknown
- 1999-04-11 AR ARP990105589A patent/AR024840A1/es unknown
- 1999-11-03 YU YU44301A patent/YU44301A/sh unknown
- 1999-11-03 AP APAP/P/2001/002188A patent/AP2001002188A0/en unknown
- 1999-11-03 AU AU63614/99A patent/AU761711B2/en not_active Ceased
- 1999-11-03 EP EP99951040A patent/EP1140931B1/en not_active Expired - Lifetime
- 1999-11-03 AT AT99951040T patent/ATE260278T1/de not_active IP Right Cessation
- 1999-11-03 TR TR2001/01979T patent/TR200101979T2/xx unknown
- 1999-11-03 NZ NZ511964A patent/NZ511964A/en unknown
- 1999-11-03 ID IDW00200101401A patent/ID30117A/id unknown
- 1999-11-03 CN CN99815202A patent/CN1332740A/zh active Pending
- 1999-11-03 DE DE69915113T patent/DE69915113T2/de not_active Expired - Fee Related
- 1999-11-03 DK DK99951040T patent/DK1140931T3/da active
- 1999-11-03 IL IL14338599A patent/IL143385A0/xx unknown
- 1999-11-03 BR BR9916807-3A patent/BR9916807A/pt not_active Application Discontinuation
- 1999-11-03 CZ CZ20012386A patent/CZ291163B6/cs not_active IP Right Cessation
- 1999-11-03 OA OA1200100172A patent/OA11742A/en unknown
- 1999-11-03 CA CA002356985A patent/CA2356985C/en not_active Expired - Fee Related
- 1999-11-03 KR KR10-2001-7008261A patent/KR100417506B1/ko not_active IP Right Cessation
- 1999-11-03 SK SK900-2001A patent/SK9002001A3/sk unknown
- 1999-11-03 EE EEP200100346A patent/EE04439B1/xx not_active IP Right Cessation
- 1999-11-03 JP JP2000591039A patent/JP2002533463A/ja active Pending
- 1999-11-03 EA EA200100517A patent/EA003099B1/ru not_active IP Right Cessation
- 1999-11-03 HU HU0104852A patent/HUP0104852A3/hu unknown
- 1999-11-03 GE GEAP19995963A patent/GEP20043227B/en unknown
- 1999-11-03 ES ES99951040T patent/ES2214892T3/es not_active Expired - Lifetime
- 1999-11-03 PT PT99951040T patent/PT1140931E/pt unknown
- 1999-11-03 WO PCT/IB1999/001772 patent/WO2000039128A1/en active IP Right Grant
- 1999-11-04 PE PE1999001116A patent/PE20001234A1/es not_active Application Discontinuation
- 1999-11-05 TW TW088119374A patent/TW523514B/zh not_active IP Right Cessation
- 1999-11-10 MA MA25844A patent/MA26706A1/fr unknown
- 1999-11-10 DZ DZ990233A patent/DZ2933A1/xx active
- 1999-11-17 TN TNTNSN99218A patent/TNSN99218A1/fr unknown
- 1999-11-18 CO CO99072703A patent/CO5150179A1/es unknown
- 1999-12-06 US US09/454,509 patent/US6525196B1/en not_active Expired - Fee Related
- 1999-12-07 PA PA19998486701A patent/PA8486701A1/es unknown
- 1999-12-23 GT GT199900224A patent/GT199900224A/es unknown
-
2001
- 2001-05-22 IS IS5951A patent/IS5951A/is unknown
- 2001-06-19 CR CR6398A patent/CR6398A/es not_active Application Discontinuation
- 2001-06-20 ZA ZA200105041A patent/ZA200105041B/en unknown
- 2001-06-27 NO NO20013215A patent/NO20013215L/no not_active Application Discontinuation
- 2001-06-28 HR HR20010488A patent/HRP20010488A2/hr not_active Application Discontinuation
- 2001-07-16 BG BG105710A patent/BG105710A/xx unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GT200100137A (es) | Pro-drogas de derivados de 4-fenil-piridina. | |
HN1999000149A (es) | Derivados de 4,4-biarilpiperidina | |
PA8436201A1 (es) | Derivados 6,5-heterobiciclicos sustituidos | |
PA8486701A1 (es) | Antagonistas de 5ht1 para terapia antidepresiva | |
PA8575401A1 (es) | Derivados de heteroarilamida benzocondensada de tienopiridinas utiles como agentes terapeuticos, composiciones farmaceuticas que incluyen a los mismos y metrodos para su uso | |
SV1999000251A (es) | Derivados de 3,3-biarilpiperidina y 2,2-biarilmorfolina ref. pcl0085/82805/bb | |
BR0115436A (pt) | Compostos de piperazinilpirazina atuando como antagonistas do receptor 5ht-2 de serotonina | |
PA8518701A1 (es) | Derivados de tiofeno utiles como agentes anticancerosos | |
ES2193508T3 (es) | Ftalizinonas. | |
PA8578601A1 (es) | Derivados de 2,2- difenil-benzodioxol | |
UY26872A1 (es) | Derivados de la 4- fenil piridina | |
ES2189235T3 (es) | 6-fenilfenantridinas sustituidas. | |
UY26958A1 (es) | Nuevos agentes anticolinérgicos que se pueden emplear como medicamentos así como procedimiento para su preparación | |
AR006390A1 (es) | Derivados de lactama | |
UY28040A1 (es) | Antagonistas de cgrp elegidos, procedimiento para su preparación, así como su empleo como medicamentos. | |
BRPI0418031A (pt) | inibidores de quinase fosfonato-substituìdos | |
DK1200426T3 (da) | Substituerede thien-3-yl-sulfonylamino(thio)carbonyl-tiazolin(thi)oner | |
GT200100254A (es) | Nuevas imidazotriazinonas sustituidas | |
PA8576001A1 (es) | "difenilazetidinonas sustituidas en anillo, procedimiento para su preparacion , medicamentos que comprenden estos compuestos y su uso". | |
GT200900026A (es) | Derivados de 5,6 -bisaril-2-piridin-carboxamida, su preparacion y su aplicacion en terapeutica como antagonistas de los receptores de urotensina ii | |
PA8487701A1 (es) | Derivados de 3,3-biarilpiperidina y 2,2-biarilmorfolina | |
PA8573501A1 (es) | Derivados de benzoxazina y su empleo | |
SE9901077D0 (sv) | Novel use | |
AR021843A1 (es) | Derivados de propanolamina sustituidos con heterociclos, procedimiento para su preparacion, y su utilizacion. | |
PA8582201A1 (es) | Indoles 2,7-sustituidos |