PA8576001A1 - "difenilazetidinonas sustituidas en anillo, procedimiento para su preparacion , medicamentos que comprenden estos compuestos y su uso". - Google Patents

"difenilazetidinonas sustituidas en anillo, procedimiento para su preparacion , medicamentos que comprenden estos compuestos y su uso".

Info

Publication number
PA8576001A1
PA8576001A1 PA20038576001A PA8576001A PA8576001A1 PA 8576001 A1 PA8576001 A1 PA 8576001A1 PA 20038576001 A PA20038576001 A PA 20038576001A PA 8576001 A PA8576001 A PA 8576001A PA 8576001 A1 PA8576001 A1 PA 8576001A1
Authority
PA
Panama
Prior art keywords
compounds
difenilazetidinonas
medications
understanding
replaced
Prior art date
Application number
PA20038576001A
Other languages
English (en)
Inventor
Heiner Glombik
Wendelin Frick
Hans-Ludwig Schaefer
Werner Kramer
Gerhard Jaehne
Stefanie Flohr
Hubert Heuer
Lindenschmidt Andreas
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of PA8576001A1 publication Critical patent/PA8576001A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Abstract

DIFENILAZETIDINONAS SUSTITUIDAS EN EL ANILLO, PROCEDIMIENTO PARA SU PREPARACION, MEDICAMENTOS QUE COMPRENDEN ESTOS COMPUESTOS Y SU USO. LA INVENCION SE REFIERE A COMPUESTOS DE LA FORMULA I, EN LA QUE R1, R2, R3, R4, R5 Y R6 TIENEN LOS SIGNIFICADOS DADOS MAS ARRIBA, Y A SUS SALES FISIOLOGICAMENTE ACEPTABLES. LOS COMPUESTOS SON CONVENIENTES PARA USAR, POR EJEMPLO, COMO HIPOLIPIDEMICOS.
PA20038576001A 2002-06-19 2003-06-18 "difenilazetidinonas sustituidas en anillo, procedimiento para su preparacion , medicamentos que comprenden estos compuestos y su uso". PA8576001A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10227506A DE10227506A1 (de) 2002-06-19 2002-06-19 Ringsubstituierte Diphenylazetidinone, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung

Publications (1)

Publication Number Publication Date
PA8576001A1 true PA8576001A1 (es) 2004-02-07

Family

ID=29719281

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20038576001A PA8576001A1 (es) 2002-06-19 2003-06-18 "difenilazetidinonas sustituidas en anillo, procedimiento para su preparacion , medicamentos que comprenden estos compuestos y su uso".

Country Status (30)

Country Link
EP (1) EP1517892B1 (es)
JP (1) JP2005533072A (es)
CN (1) CN1662493A (es)
AR (1) AR039689A1 (es)
AT (1) ATE478842T1 (es)
AU (1) AU2003242616B2 (es)
BR (1) BR0311940A (es)
CA (1) CA2490109A1 (es)
DE (2) DE10227506A1 (es)
EC (1) ECSP045498A (es)
HN (1) HN2003000183A (es)
HR (1) HRP20041203A2 (es)
IL (1) IL165791A0 (es)
MA (1) MA27252A1 (es)
MX (1) MXPA04012236A (es)
MY (1) MY135850A (es)
NO (1) NO20050073L (es)
NZ (1) NZ537304A (es)
OA (1) OA12868A (es)
PA (1) PA8576001A1 (es)
PE (1) PE20040577A1 (es)
PL (1) PL372690A1 (es)
RS (1) RS108504A (es)
RU (1) RU2315754C2 (es)
SV (1) SV2004001549A (es)
TN (1) TNSN04255A1 (es)
TW (1) TW200404774A (es)
UY (1) UY27851A1 (es)
WO (1) WO2004000804A1 (es)
ZA (1) ZA200409381B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0215579D0 (en) 2002-07-05 2002-08-14 Astrazeneca Ab Chemical compounds
US7447226B2 (en) * 2003-10-31 2008-11-04 International Business Machines Corporation Methods and apparatus for continuous connectivity between mobile device and network using dynamic connection spreading
US7871998B2 (en) 2003-12-23 2011-01-18 Astrazeneca Ab Diphenylazetidinone derivatives possessing cholesterol absorption inhibitory activity
NZ555320A (en) 2004-12-03 2010-11-26 Schering Corp Substituted piperazines as CB1 antagonists
MX2007012253A (es) * 2005-04-04 2007-12-07 Univ Pontificia Catolica Chile Uso de ezetimibe para la prevencion y tratamiento de calculos de colesterol en la via biliar.
ATE450526T1 (de) 2005-06-20 2009-12-15 Schering Corp Als antagonisten von histamin h3 geeignete piperidinderivate
SA06270191B1 (ar) 2005-06-22 2010-03-29 استرازينيكا ايه بي مشتقات من 2- أزيتيدينون جديدة باعتبارها مثبطات لامتصاص الكوليسترول لعلاج حالات فرط نسبة الدهون في الدم
TW200811098A (en) 2006-04-27 2008-03-01 Astrazeneca Ab Chemical compounds
CA2666193A1 (en) 2006-08-08 2008-02-14 Sanofi-Aventis Arylaminoaryl-alkyl-substituted imidazolidine-2,4-diones, process for preparing them, medicaments comprising these compounds, and their use
KR20090091120A (ko) * 2006-11-02 2009-08-26 사노피-아벤티스 도이칠란트 게엠베하 향상된 약리학적 특성을 갖는 피페라진-1-설폰산으로 치환된 신규한 디페닐아제티디논
DE102007002260A1 (de) 2007-01-16 2008-07-31 Sanofi-Aventis Verwendung von substituierten Pyranonsäurederivaten zur Herstellung von Medikamenten zur Behandlung des Metabolischen Syndroms
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE102007054497B3 (de) 2007-11-13 2009-07-23 Sanofi-Aventis Deutschland Gmbh Neue kristalline Diphenylazetidinonhydrate und Verfahren zu deren Herstellung
EP2310372B1 (en) 2008-07-09 2012-05-23 Sanofi Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
WO2010068601A1 (en) 2008-12-08 2010-06-17 Sanofi-Aventis A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
US9212175B2 (en) 2009-03-06 2015-12-15 Lipideon Biotechnology Ag Pharmaceutical hypocholesterolemic compositions
CN101993403B (zh) 2009-08-11 2012-07-11 浙江海正药业股份有限公司 氮杂环丁酮类化合物及医药应用
DK2470552T3 (en) 2009-08-26 2014-02-17 Sanofi Sa NOVEL, CRYSTALLINE, heteroaromatic FLUORGLYCOSIDHYDRATER, MEDICINES COVERING THESE COMPOUNDS AND THEIR USE
US8933024B2 (en) 2010-06-18 2015-01-13 Sanofi Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases
WO2012120055A1 (de) 2011-03-08 2012-09-13 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8828994B2 (en) 2011-03-08 2014-09-09 Sanofi Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
EP2683700B1 (de) 2011-03-08 2015-02-18 Sanofi Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8901114B2 (en) 2011-03-08 2014-12-02 Sanofi Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
WO2012120053A1 (de) 2011-03-08 2012-09-13 Sanofi Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5656624A (en) * 1994-12-21 1997-08-12 Schering Corporation 4-[(heterocycloalkyl or heteroaromatic)-substituted phenyl]-2-azetidinones useful as hypolipidemic agents
HU226822B1 (en) * 1995-10-31 2009-11-30 Schering Corp Hypocholesterolemic sugar-substituted 2-azetidinones, and pharmaceutical compns. contg. them
DE10042447A1 (de) * 2000-08-29 2002-03-28 Aventis Pharma Gmbh Protein aus dem Darm von Wirbeltieren, welches Cholesterin absorbiert, sowie Verwendung dieses Proteins zur Identifizierung von Inhibitoren des intestinalen Cholesterintransports

Also Published As

Publication number Publication date
SV2004001549A (es) 2004-03-19
MA27252A1 (fr) 2005-03-01
MXPA04012236A (es) 2005-02-25
ATE478842T1 (de) 2010-09-15
BR0311940A (pt) 2005-04-05
AU2003242616A1 (en) 2004-01-06
HRP20041203A2 (en) 2005-06-30
HN2003000183A (es) 2003-08-01
PL372690A1 (en) 2005-07-25
RS108504A (en) 2007-02-05
CA2490109A1 (en) 2003-12-31
DE10227506A1 (de) 2004-01-08
ECSP045498A (es) 2005-03-10
AR039689A1 (es) 2005-03-09
MY135850A (en) 2008-07-31
NO20050073L (no) 2005-01-06
EP1517892B1 (de) 2010-08-25
TW200404774A (en) 2004-04-01
ZA200409381B (en) 2006-05-31
WO2004000804A1 (de) 2003-12-31
OA12868A (en) 2006-09-15
TNSN04255A1 (en) 2007-03-12
RU2315754C2 (ru) 2008-01-27
AU2003242616B2 (en) 2008-12-11
IL165791A0 (en) 2006-01-15
DE50313017D1 (de) 2010-10-07
NZ537304A (en) 2005-10-28
EP1517892A1 (de) 2005-03-30
PE20040577A1 (es) 2004-10-11
UY27851A1 (es) 2003-12-31
RU2005101091A (ru) 2005-07-10
CN1662493A (zh) 2005-08-31
JP2005533072A (ja) 2005-11-04

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