OA12519A - Bridged piperazine derivatives. - Google Patents
Bridged piperazine derivatives. Download PDFInfo
- Publication number
- OA12519A OA12519A OA1200300093A OA1200300093A OA12519A OA 12519 A OA12519 A OA 12519A OA 1200300093 A OA1200300093 A OA 1200300093A OA 1200300093 A OA1200300093 A OA 1200300093A OA 12519 A OA12519 A OA 12519A
- Authority
- OA
- OAPI
- Prior art keywords
- crc6
- amino
- alkyl
- carboxy
- formula
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/16—Central respiratory analeptics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P31/12—Antivirals
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- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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- A—HUMAN NECESSITIES
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- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A61P31/22—Antivirals for DNA viruses for herpes viruses
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- A—HUMAN NECESSITIES
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- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/08—Vasodilators for multiple indications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Biotechnology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Emergency Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Transplantation (AREA)
- Biomedical Technology (AREA)
- Obesity (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24180400P | 2000-10-19 | 2000-10-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
OA12519A true OA12519A (en) | 2006-05-30 |
Family
ID=22912245
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
OA1200300093A OA12519A (en) | 2000-10-19 | 2001-10-04 | Bridged piperazine derivatives. |
Country Status (37)
Country | Link |
---|---|
US (1) | US20020119961A1 (fr) |
EP (1) | EP1326867A2 (fr) |
JP (1) | JP2004511558A (fr) |
KR (1) | KR20030040548A (fr) |
CN (1) | CN1471534A (fr) |
AP (1) | AP2001002306A0 (fr) |
AR (1) | AR035354A1 (fr) |
AU (1) | AU2001292160A1 (fr) |
BG (1) | BG107655A (fr) |
BR (1) | BR0114697A (fr) |
CA (1) | CA2423789A1 (fr) |
CZ (1) | CZ20031013A3 (fr) |
DO (1) | DOP2001000268A (fr) |
EA (1) | EA200300392A1 (fr) |
EC (1) | ECSP034561A (fr) |
EE (1) | EE200300189A (fr) |
GE (1) | GEP20053617B (fr) |
GT (1) | GT200100209A (fr) |
HN (1) | HN2001000235A (fr) |
HR (1) | HRP20030298A2 (fr) |
HU (1) | HUP0301442A3 (fr) |
IL (1) | IL154912A0 (fr) |
IS (1) | IS6747A (fr) |
MA (1) | MA26953A1 (fr) |
MX (1) | MXPA03003475A (fr) |
NO (1) | NO20031572L (fr) |
NZ (1) | NZ524742A (fr) |
OA (1) | OA12519A (fr) |
PA (1) | PA8530901A1 (fr) |
PE (1) | PE20020587A1 (fr) |
PL (1) | PL362077A1 (fr) |
SK (1) | SK4642003A3 (fr) |
SV (1) | SV2002000694A (fr) |
TN (1) | TNSN01144A1 (fr) |
WO (1) | WO2002032901A2 (fr) |
YU (1) | YU30603A (fr) |
ZA (1) | ZA200302157B (fr) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR0210060A (pt) * | 2001-05-10 | 2004-08-17 | Agouron Pharma | Ligandos de fkbp de heterobiciclos |
EP1430041A2 (fr) | 2001-06-20 | 2004-06-23 | Pfizer Products Inc. | Nouveaux derives d'acide sulfonique |
JP2005507923A (ja) | 2001-10-22 | 2005-03-24 | ファイザー・プロダクツ・インク | Ccr1受容体アンタゴニスト活性を有するピペラジン誘導体 |
US7157464B2 (en) | 2002-06-12 | 2007-01-02 | Chemocentryx, Inc. | Substituted piperazines |
US7589199B2 (en) | 2002-06-12 | 2009-09-15 | Chemocentryx, Inc. | Substituted piperazines |
US20050256130A1 (en) * | 2002-06-12 | 2005-11-17 | Chemocentryx, Inc. | Substituted piperazines |
US7842693B2 (en) * | 2002-06-12 | 2010-11-30 | Chemocentryx, Inc. | Substituted piperazines |
US7435831B2 (en) * | 2004-03-03 | 2008-10-14 | Chemocentryx, Inc. | Bicyclic and bridged nitrogen heterocycles |
US7435830B2 (en) * | 2004-03-03 | 2008-10-14 | Chemocentryx, Inc. | Bicyclic and bridged nitrogen heterocycles |
GB0409236D0 (en) * | 2004-04-26 | 2004-05-26 | Novartis Ag | Organic compounds |
ES2439969T3 (es) * | 2008-07-16 | 2014-01-27 | F. Hoffmann-La Roche Ag | Nuevos compuestos heterocíclicos para el tratamiento de enfermedades cardiovasculares |
WO2011104307A2 (fr) * | 2010-02-25 | 2011-09-01 | Graffinity Pharmaceuticals Gmbh | Ligands destinés à la purification d'anticorps par chromatographie d'affinité |
CN101874798B (zh) * | 2010-06-29 | 2012-08-29 | 北京大学 | 白三烯a4水解酶与环氧合酶的双功能抑制剂及其用途 |
CN105294700B (zh) * | 2014-07-01 | 2019-01-08 | 上海合全药业股份有限公司 | 一种2-氧代-3,8-二氮杂二环[3.2.1]辛烷-8-羧酸叔丁酯的制备方法 |
WO2016054123A1 (fr) | 2014-09-30 | 2016-04-07 | Lightner Derek | Procédés de production d'hétéropolycycles par bis-époxydation |
WO2020243423A1 (fr) | 2019-05-31 | 2020-12-03 | Ikena Oncology, Inc. | Inhibiteurs de tead et leurs utilisations |
AU2020282757A1 (en) | 2019-05-31 | 2021-12-23 | Ikena Oncology, Inc. | TEAD inhibitors and uses thereof |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE640616A (fr) * | 1962-12-19 | |||
US3492397A (en) * | 1967-04-07 | 1970-01-27 | Warner Lambert Pharmaceutical | Sustained release dosage in the pellet form and process thereof |
US4060598A (en) * | 1967-06-28 | 1977-11-29 | Boehringer Mannheim G.M.B.H. | Tablets coated with aqueous resin dispersions |
US3538214A (en) * | 1969-04-22 | 1970-11-03 | Merck & Co Inc | Controlled release medicinal tablets |
US4173626A (en) * | 1978-12-11 | 1979-11-06 | Merck & Co., Inc. | Sustained release indomethacin |
GB8800694D0 (en) * | 1988-01-13 | 1988-02-10 | Pfizer Ltd | Antiarrhythmic agents |
US5245028A (en) * | 1990-08-09 | 1993-09-14 | Warner-Lambert Company | Process for preparing tetracyclic amines useful as cerebrovascular agents |
AT403803B (de) * | 1996-04-19 | 1998-05-25 | Sanochemia Ltd | Neue benzazepinderivate, diese enthaltende arzneimittel und verwendung derselben zum herstellen von arzneimitteln |
US6207665B1 (en) * | 1997-06-12 | 2001-03-27 | Schering Aktiengesellschaft | Piperazine derivatives and their use as anti-inflammatory agents |
ID27544A (id) * | 1998-08-18 | 2001-04-12 | Ucb Sa | Agonis dan antagonis muskarinat |
GB9905010D0 (en) * | 1999-03-04 | 1999-04-28 | Merck Sharp & Dohme | Therapeutic agents |
US6432976B1 (en) * | 1999-10-29 | 2002-08-13 | Merck & Co., Inc. | 8-aza-bicyclo[3.2.1]octane NMDA/NR2B antagonists |
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2001
- 2001-10-04 MX MXPA03003475A patent/MXPA03003475A/es unknown
- 2001-10-04 CA CA002423789A patent/CA2423789A1/fr not_active Abandoned
- 2001-10-04 EA EA200300392A patent/EA200300392A1/ru unknown
- 2001-10-04 GE GE5131A patent/GEP20053617B/en unknown
- 2001-10-04 EE EEP200300189A patent/EE200300189A/xx unknown
- 2001-10-04 JP JP2002536283A patent/JP2004511558A/ja not_active Withdrawn
- 2001-10-04 KR KR10-2003-7005422A patent/KR20030040548A/ko not_active Application Discontinuation
- 2001-10-04 BR BR0114697-1A patent/BR0114697A/pt not_active IP Right Cessation
- 2001-10-04 CN CNA018176925A patent/CN1471534A/zh active Pending
- 2001-10-04 NZ NZ524742A patent/NZ524742A/xx unknown
- 2001-10-04 PL PL01362077A patent/PL362077A1/xx not_active Application Discontinuation
- 2001-10-04 IL IL15491201A patent/IL154912A0/xx unknown
- 2001-10-04 SK SK464-2003A patent/SK4642003A3/sk not_active Application Discontinuation
- 2001-10-04 WO PCT/IB2001/001844 patent/WO2002032901A2/fr not_active Application Discontinuation
- 2001-10-04 AU AU2001292160A patent/AU2001292160A1/en not_active Abandoned
- 2001-10-04 CZ CZ20031013A patent/CZ20031013A3/cs unknown
- 2001-10-04 AP APAP/P/2001/002306A patent/AP2001002306A0/en unknown
- 2001-10-04 OA OA1200300093A patent/OA12519A/en unknown
- 2001-10-04 YU YU30603A patent/YU30603A/sh unknown
- 2001-10-04 HU HU0301442A patent/HUP0301442A3/hu unknown
- 2001-10-04 EP EP01972389A patent/EP1326867A2/fr not_active Withdrawn
- 2001-10-05 US US09/972,177 patent/US20020119961A1/en not_active Abandoned
- 2001-10-17 PE PE2001001030A patent/PE20020587A1/es not_active Application Discontinuation
- 2001-10-17 GT GT200100209A patent/GT200100209A/es unknown
- 2001-10-17 AR ARP010104880A patent/AR035354A1/es unknown
- 2001-10-18 DO DO2001000268A patent/DOP2001000268A/es unknown
- 2001-10-18 HN HN2001000235A patent/HN2001000235A/es unknown
- 2001-10-18 TN TNTNSN01144A patent/TNSN01144A1/fr unknown
- 2001-10-18 PA PA20018530901A patent/PA8530901A1/es unknown
- 2001-10-18 SV SV2001000694A patent/SV2002000694A/es unknown
-
2003
- 2003-03-17 IS IS6747A patent/IS6747A/is unknown
- 2003-03-18 ZA ZA200302157A patent/ZA200302157B/en unknown
- 2003-03-20 BG BG107655A patent/BG107655A/bg unknown
- 2003-04-08 NO NO20031572A patent/NO20031572L/no unknown
- 2003-04-08 MA MA27098A patent/MA26953A1/fr unknown
- 2003-04-15 HR HR20030298A patent/HRP20030298A2/hr not_active Application Discontinuation
- 2003-04-16 EC EC2003004561A patent/ECSP034561A/es unknown
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