OA11061A - Preparation of Ä1s-Ä1a 2b 3b 4a(s*)ÜÜ1-(3-chloro-2-thienyl)methylÜpropylÜaminoÜ-3h-imidazoÄ4 5-bÜpyridin-3-ylÜ-n-ethyl-2 3-dihydroxycyclopentanecarboxamide - Google Patents

Preparation of Ä1s-Ä1a 2b 3b 4a(s*)ÜÜ1-(3-chloro-2-thienyl)methylÜpropylÜaminoÜ-3h-imidazoÄ4 5-bÜpyridin-3-ylÜ-n-ethyl-2 3-dihydroxycyclopentanecarboxamide Download PDF

Info

Publication number
OA11061A
OA11061A OA9900123A OA9900123A OA11061A OA 11061 A OA11061 A OA 11061A OA 9900123 A OA9900123 A OA 9900123A OA 9900123 A OA9900123 A OA 9900123A OA 11061 A OA11061 A OA 11061A
Authority
OA
OAPI
Prior art keywords
amino
chloro
thienyl
propyl
methyl
Prior art date
Application number
OA9900123A
Other languages
English (en)
Inventor
Herve Garcia
Patrick Leon
Michael K O'brien
Tory H Powner
Laurence W Reilly
Harshavadan C Shah
Michael D Thompson
Ching T Tsuei
Benoit J Vanasse
Francis L Walther
Original Assignee
Rhone Poulenc Rorer Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Pharma filed Critical Rhone Poulenc Rorer Pharma
Publication of OA11061A publication Critical patent/OA11061A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/69—Two or more oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
OA9900123A 1996-12-11 1999-06-11 Preparation of Ä1s-Ä1a 2b 3b 4a(s*)ÜÜ1-(3-chloro-2-thienyl)methylÜpropylÜaminoÜ-3h-imidazoÄ4 5-bÜpyridin-3-ylÜ-n-ethyl-2 3-dihydroxycyclopentanecarboxamide OA11061A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3276496P 1996-12-11 1996-12-11

Publications (1)

Publication Number Publication Date
OA11061A true OA11061A (en) 2002-02-27

Family

ID=21866680

Family Applications (1)

Application Number Title Priority Date Filing Date
OA9900123A OA11061A (en) 1996-12-11 1999-06-11 Preparation of Ä1s-Ä1a 2b 3b 4a(s*)ÜÜ1-(3-chloro-2-thienyl)methylÜpropylÜaminoÜ-3h-imidazoÄ4 5-bÜpyridin-3-ylÜ-n-ethyl-2 3-dihydroxycyclopentanecarboxamide

Country Status (27)

Country Link
US (2) US6143894A (no)
EP (2) EP0946550B1 (no)
JP (1) JP2001506626A (no)
KR (4) KR20060002030A (no)
CN (3) CN1660842A (no)
AP (1) AP1063A (no)
AT (1) ATE301120T1 (no)
AU (1) AU738581B2 (no)
BG (1) BG63805B1 (no)
BR (1) BR9713705A (no)
CA (1) CA2274630C (no)
DE (1) DE69733897T2 (no)
DK (1) DK0946550T3 (no)
EA (1) EA001989B1 (no)
ES (1) ES2242984T3 (no)
HK (2) HK1023998A1 (no)
HU (1) HUP0000342A3 (no)
IL (1) IL130397A (no)
MX (1) MXPA03006730A (no)
NO (2) NO319722B1 (no)
OA (1) OA11061A (no)
PT (1) PT946550E (no)
SI (1) SI0946550T1 (no)
SK (1) SK71199A3 (no)
UA (1) UA54479C2 (no)
WO (1) WO1998025921A1 (no)
ZA (1) ZA9711035B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1140933T3 (da) 1998-12-31 2004-12-20 Aventis Pharma Inc Fremgangsmåde til fremstilling af N6-substituerede deaza-adenosinderivater
US7291603B2 (en) * 2002-07-24 2007-11-06 Ptc Therapeutics, Inc. Nucleoside compounds and their use for treating cancer and diseases associated with somatic mutations
FR2846656B1 (fr) * 2002-11-05 2004-12-24 Servier Lab Nouveaux derives d'imidazopyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2095960T3 (es) * 1990-09-25 1997-03-01 Rhone Poulenc Rorer Int Compuestos que tienen propiedades antihipertensivas y antiisquemicas.
HRP980375A2 (en) * 1997-07-03 1999-04-30 Argyrios Georgios Arvanitis Imidazopyrimidines and imidazopyridines for the treatment of neurological disorders
ES2191489T3 (es) * 1998-12-21 2003-09-01 Aventis Pharma Inc Proceso para preparar derivados de deaza-adenosina sustituidos en n6.

Also Published As

Publication number Publication date
WO1998025921A1 (en) 1998-06-18
KR100571690B1 (ko) 2006-04-18
SI0946550T1 (en) 2005-10-31
CN1090630C (zh) 2002-09-11
CN1394859A (zh) 2003-02-05
CN1660842A (zh) 2005-08-31
EP0946550A4 (en) 2003-05-14
CN1191251C (zh) 2005-03-02
IL130397A0 (en) 2000-06-01
EA001989B1 (ru) 2001-10-22
JP2001506626A (ja) 2001-05-22
EA199900527A1 (ru) 2000-02-28
UA54479C2 (uk) 2003-03-17
BG63805B1 (bg) 2003-01-31
HUP0000342A2 (hu) 2000-10-28
EP0946550B1 (en) 2005-08-03
SK71199A3 (en) 2000-07-11
NO992795L (no) 1999-08-10
HUP0000342A3 (en) 2001-01-29
KR20060002030A (ko) 2006-01-06
KR20060002029A (ko) 2006-01-06
KR20000057505A (ko) 2000-09-15
KR20050046793A (ko) 2005-05-18
NO20052327L (no) 1999-08-10
HK1023998A1 (en) 2000-09-29
BR9713705A (pt) 2000-05-09
EP1609791A1 (en) 2005-12-28
KR100510389B1 (ko) 2005-08-31
PT946550E (pt) 2005-09-30
IL130397A (en) 2005-11-20
ZA9711035B (en) 1998-06-15
AP1063A (en) 2002-04-26
BG103484A (en) 2000-06-30
ATE301120T1 (de) 2005-08-15
DE69733897D1 (de) 2005-09-08
NO20052327D0 (no) 2005-05-12
HK1051862A1 (en) 2003-08-22
ES2242984T3 (es) 2005-11-16
AU5360798A (en) 1998-07-03
US6235909B1 (en) 2001-05-22
NO319722B1 (no) 2005-09-05
AP9901550A0 (en) 1999-06-30
US6143894A (en) 2000-11-07
DK0946550T3 (da) 2005-08-29
CA2274630C (en) 2000-10-03
EP0946550A1 (en) 1999-10-06
NO992795D0 (no) 1999-06-09
CN1240445A (zh) 2000-01-05
MXPA03006730A (es) 2003-10-24
DE69733897T2 (de) 2006-06-01
AU738581B2 (en) 2001-09-20

Similar Documents

Publication Publication Date Title
KR940006594B1 (ko) 이미다조피리딘 화합물의 제조방법
KR910000897B1 (ko) 레베카마이신 동족체
US6924291B2 (en) Process for making spiro isobenzofuranone compounds
US6429315B1 (en) Process for preparing N6-substituted adenosine derivatives
CZ20013658A3 (cs) Syntéza a krystalizace sloučenin obsahujících piperazinový kruh
OA11061A (en) Preparation of Ä1s-Ä1a 2b 3b 4a(s*)ÜÜ1-(3-chloro-2-thienyl)methylÜpropylÜaminoÜ-3h-imidazoÄ4 5-bÜpyridin-3-ylÜ-n-ethyl-2 3-dihydroxycyclopentanecarboxamide
KR20180116371A (ko) 4-알콕시-3-히드록시피콜린산의 제조 방법
NZ254628A (en) Synthesis of 2,6-dichloro-5-fluoronicotinic acid or -nicotinoyl chloride
IL152921A (en) Preparation of 4-hydroxy-3-nitro-2(1h)-pyridone from 2-hydroxy-3-cyano-4-methoxypyridine
EP1175420B1 (en) Process for preparing n6-substituted deaza-adenosine derivatives
JP3511788B2 (ja) ７−アミノ−２，３−ジヒドロ−２−オキソ−ピリド ［２，３−ｄ］ ピリミジン及びその製造法
JP2507505B2 (ja) セファロスポリン誘導体の新規製造方法
MXPA99005488A (en) PREPARATION OF [1S-[1a,2b,3b,4a(S*)]]-4-[7-[[1-(3-CHLORO-2-THIENYL) METHYL]PROPYL]AMINO]-3H-IMIDAZO[4,5-b]PYRIDIN-3-yl]-N-ETHYL-2,3-DIHYDROXYCYCLOPENTANECARBOXAMIDE
US3155673A (en) Process for preparing vitamin b
KR0151818B1 (ko) 피리딜 이미다졸 유도체의 제조방법
AU646096B2 (en) Method for the preparation of 5,11-dihydro-6H-dipyrido (3,2-b:2',3'-e)(1,4)diazepines
JPWO2007011021A1 (ja) イミダゾチアゾール誘導体の製造方法
JPH01268700A (ja) ２’‐デオキシ‐５，６‐ジヒドロ‐５‐フルオロ‐６‐ヒドロキシウリジンおよびその製造法
JPH06279449A (ja) ４−アミノピリジン誘導体の製造方法