HK1051862A1 - Preparation of Ä1S-Ä1A,2B,3B,4A(S*)ÜÜ-4-Ä7-ÄÄ1-(3-chloro-2-thienyl)methylÜpropylÜaminoÜ-3H-imidazoÄ4,5-BÜpyridin-3-ylÜ-N-ethyl-2,3-dihydroxycyclopentanecarboxamide. - Google Patents

Preparation of Ä1S-Ä1A,2B,3B,4A(S*)ÜÜ-4-Ä7-ÄÄ1-(3-chloro-2-thienyl)methylÜpropylÜaminoÜ-3H-imidazoÄ4,5-BÜpyridin-3-ylÜ-N-ethyl-2,3-dihydroxycyclopentanecarboxamide.

Info

Publication number
HK1051862A1
HK1051862A1 HK03104142A HK03104142A HK1051862A1 HK 1051862 A1 HK1051862 A1 HK 1051862A1 HK 03104142 A HK03104142 A HK 03104142A HK 03104142 A HK03104142 A HK 03104142A HK 1051862 A1 HK1051862 A1 HK 1051862A1
Authority
HK
Hong Kong
Prior art keywords
ylü
methylüpropylüaminoü
imidazoä4
büpyridin
dihydroxycyclopentanecarboxamide
Prior art date
Application number
HK03104142A
Other languages
English (en)
Inventor
Michael K Obrien
Herve Garcia
Patrick Leon
Tory H Powner
Laurence W Reilly
Harshavadan C Shah
Michael D Thompson
Ching T Tsuei
Benoit J Vanasse
Francis L Walther
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of HK1051862A1 publication Critical patent/HK1051862A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/69—Two or more oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
HK03104142A 1996-12-11 2003-06-11 Preparation of Ä1S-Ä1A,2B,3B,4A(S*)ÜÜ-4-Ä7-ÄÄ1-(3-chloro-2-thienyl)methylÜpropylÜaminoÜ-3H-imidazoÄ4,5-BÜpyridin-3-ylÜ-N-ethyl-2,3-dihydroxycyclopentanecarboxamide. HK1051862A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3276496P 1996-12-11 1996-12-11

Publications (1)

Publication Number Publication Date
HK1051862A1 true HK1051862A1 (en) 2003-08-22

Family

ID=21866680

Family Applications (2)

Application Number Title Priority Date Filing Date
HK00103182A HK1023998A1 (en) 1996-12-11 2000-05-30 Preparation of[1s-[1a,2b,3b,4a(s*)]]-4-[7-[[1-(3-chloro-2-thienyl) methyl] propyl]amino]-3h-imidazo [4,5-b]pyridin-3-yl]-n-ethyl-2,3-dihydroxycyclopentanecarbox amide
HK03104142A HK1051862A1 (en) 1996-12-11 2003-06-11 Preparation of Ä1S-Ä1A,2B,3B,4A(S*)ÜÜ-4-Ä7-ÄÄ1-(3-chloro-2-thienyl)methylÜpropylÜaminoÜ-3H-imidazoÄ4,5-BÜpyridin-3-ylÜ-N-ethyl-2,3-dihydroxycyclopentanecarboxamide.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK00103182A HK1023998A1 (en) 1996-12-11 2000-05-30 Preparation of[1s-[1a,2b,3b,4a(s*)]]-4-[7-[[1-(3-chloro-2-thienyl) methyl] propyl]amino]-3h-imidazo [4,5-b]pyridin-3-yl]-n-ethyl-2,3-dihydroxycyclopentanecarbox amide

Country Status (27)

Country Link
US (2) US6143894A (xx)
EP (2) EP1609791A1 (xx)
JP (1) JP2001506626A (xx)
KR (4) KR20060002029A (xx)
CN (3) CN1090630C (xx)
AP (1) AP1063A (xx)
AT (1) ATE301120T1 (xx)
AU (1) AU738581B2 (xx)
BG (1) BG63805B1 (xx)
BR (1) BR9713705A (xx)
CA (1) CA2274630C (xx)
DE (1) DE69733897T2 (xx)
DK (1) DK0946550T3 (xx)
EA (1) EA001989B1 (xx)
ES (1) ES2242984T3 (xx)
HK (2) HK1023998A1 (xx)
HU (1) HUP0000342A3 (xx)
IL (1) IL130397A (xx)
MX (1) MXPA03006730A (xx)
NO (2) NO319722B1 (xx)
OA (1) OA11061A (xx)
PT (1) PT946550E (xx)
SI (1) SI0946550T1 (xx)
SK (1) SK71199A3 (xx)
UA (1) UA54479C2 (xx)
WO (1) WO1998025921A1 (xx)
ZA (1) ZA9711035B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1140933T3 (da) 1998-12-31 2004-12-20 Aventis Pharma Inc Fremgangsmåde til fremstilling af N6-substituerede deaza-adenosinderivater
US7291603B2 (en) * 2002-07-24 2007-11-06 Ptc Therapeutics, Inc. Nucleoside compounds and their use for treating cancer and diseases associated with somatic mutations
FR2846656B1 (fr) * 2002-11-05 2004-12-24 Servier Lab Nouveaux derives d'imidazopyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992005177A1 (en) * 1990-09-25 1992-04-02 Rhone-Poulenc Rorer International (Holdings) Inc. Compounds having antihypertensive and anti-ischemic properties
WO1999001454A1 (en) * 1997-07-03 1999-01-14 Du Pont Pharmaceuticals Company Imidazopyrimidines and imidazopyridines for the treatment of neurological disorders
ID30118A (id) * 1998-12-21 2001-11-08 Aventis Pharm Prod Inc Proses pembuatan turunan-turunan daeza-adenosin tersubstitusi-n6

Also Published As

Publication number Publication date
HUP0000342A3 (en) 2001-01-29
HK1023998A1 (en) 2000-09-29
NO319722B1 (no) 2005-09-05
US6235909B1 (en) 2001-05-22
EP0946550A4 (en) 2003-05-14
CA2274630C (en) 2000-10-03
CN1394859A (zh) 2003-02-05
DK0946550T3 (da) 2005-08-29
CN1240445A (zh) 2000-01-05
KR20000057505A (ko) 2000-09-15
AP9901550A0 (en) 1999-06-30
IL130397A0 (en) 2000-06-01
SK71199A3 (en) 2000-07-11
NO992795D0 (no) 1999-06-09
EP0946550B1 (en) 2005-08-03
CN1090630C (zh) 2002-09-11
EP0946550A1 (en) 1999-10-06
WO1998025921A1 (en) 1998-06-18
MXPA03006730A (es) 2003-10-24
HUP0000342A2 (hu) 2000-10-28
EP1609791A1 (en) 2005-12-28
AU5360798A (en) 1998-07-03
EA199900527A1 (ru) 2000-02-28
PT946550E (pt) 2005-09-30
JP2001506626A (ja) 2001-05-22
CN1660842A (zh) 2005-08-31
KR20060002029A (ko) 2006-01-06
OA11061A (en) 2002-02-27
AP1063A (en) 2002-04-26
BG103484A (en) 2000-06-30
KR100571690B1 (ko) 2006-04-18
KR20050046793A (ko) 2005-05-18
UA54479C2 (uk) 2003-03-17
DE69733897T2 (de) 2006-06-01
BG63805B1 (bg) 2003-01-31
BR9713705A (pt) 2000-05-09
NO20052327L (no) 1999-08-10
ES2242984T3 (es) 2005-11-16
NO20052327D0 (no) 2005-05-12
NO992795L (no) 1999-08-10
ZA9711035B (en) 1998-06-15
KR100510389B1 (ko) 2005-08-31
AU738581B2 (en) 2001-09-20
EA001989B1 (ru) 2001-10-22
IL130397A (en) 2005-11-20
CN1191251C (zh) 2005-03-02
ATE301120T1 (de) 2005-08-15
SI0946550T1 (en) 2005-10-31
US6143894A (en) 2000-11-07
DE69733897D1 (de) 2005-09-08
KR20060002030A (ko) 2006-01-06

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20081124