OA11061A - Preparation of Ä1s-Ä1a 2b 3b 4a(s*)ÜÜ1-(3-chloro-2-thienyl)methylÜpropylÜaminoÜ-3h-imidazoÄ4 5-bÜpyridin-3-ylÜ-n-ethyl-2 3-dihydroxycyclopentanecarboxamide - Google Patents

Preparation of Ä1s-Ä1a 2b 3b 4a(s*)ÜÜ1-(3-chloro-2-thienyl)methylÜpropylÜaminoÜ-3h-imidazoÄ4 5-bÜpyridin-3-ylÜ-n-ethyl-2 3-dihydroxycyclopentanecarboxamide Download PDF

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Publication number
OA11061A
OA11061A OA9900123A OA9900123A OA11061A OA 11061 A OA11061 A OA 11061A OA 9900123 A OA9900123 A OA 9900123A OA 9900123 A OA9900123 A OA 9900123A OA 11061 A OA11061 A OA 11061A
Authority
OA
OAPI
Prior art keywords
amino
chloro
thienyl
propyl
methyl
Prior art date
Application number
OA9900123A
Other languages
English (en)
Inventor
Herve Garcia
Patrick Leon
Michael K O'brien
Tory H Powner
Laurence W Reilly
Harshavadan C Shah
Michael D Thompson
Ching T Tsuei
Benoit J Vanasse
Francis L Walther
Original Assignee
Rhone Poulenc Rorer Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Pharma filed Critical Rhone Poulenc Rorer Pharma
Publication of OA11061A publication Critical patent/OA11061A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/69—Two or more oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
OA9900123A 1996-12-11 1999-06-11 Preparation of Ä1s-Ä1a 2b 3b 4a(s*)ÜÜ1-(3-chloro-2-thienyl)methylÜpropylÜaminoÜ-3h-imidazoÄ4 5-bÜpyridin-3-ylÜ-n-ethyl-2 3-dihydroxycyclopentanecarboxamide OA11061A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3276496P 1996-12-11 1996-12-11

Publications (1)

Publication Number Publication Date
OA11061A true OA11061A (en) 2002-02-27

Family

ID=21866680

Family Applications (1)

Application Number Title Priority Date Filing Date
OA9900123A OA11061A (en) 1996-12-11 1999-06-11 Preparation of Ä1s-Ä1a 2b 3b 4a(s*)ÜÜ1-(3-chloro-2-thienyl)methylÜpropylÜaminoÜ-3h-imidazoÄ4 5-bÜpyridin-3-ylÜ-n-ethyl-2 3-dihydroxycyclopentanecarboxamide

Country Status (27)

Country Link
US (2) US6143894A (es)
EP (2) EP1609791A1 (es)
JP (1) JP2001506626A (es)
KR (4) KR20060002029A (es)
CN (3) CN1090630C (es)
AP (1) AP1063A (es)
AT (1) ATE301120T1 (es)
AU (1) AU738581B2 (es)
BG (1) BG63805B1 (es)
BR (1) BR9713705A (es)
CA (1) CA2274630C (es)
DE (1) DE69733897T2 (es)
DK (1) DK0946550T3 (es)
EA (1) EA001989B1 (es)
ES (1) ES2242984T3 (es)
HK (2) HK1023998A1 (es)
HU (1) HUP0000342A3 (es)
IL (1) IL130397A (es)
MX (1) MXPA03006730A (es)
NO (2) NO319722B1 (es)
OA (1) OA11061A (es)
PT (1) PT946550E (es)
SI (1) SI0946550T1 (es)
SK (1) SK71199A3 (es)
UA (1) UA54479C2 (es)
WO (1) WO1998025921A1 (es)
ZA (1) ZA9711035B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE275565T1 (de) 1998-12-31 2004-09-15 Aventis Pharma Inc Verfahren zur herstellung von n6-substituierten deaza-adenosinderivaten
US7291603B2 (en) * 2002-07-24 2007-11-06 Ptc Therapeutics, Inc. Nucleoside compounds and their use for treating cancer and diseases associated with somatic mutations
FR2846656B1 (fr) * 2002-11-05 2004-12-24 Servier Lab Nouveaux derives d'imidazopyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0550631B1 (en) * 1990-09-25 1997-01-02 Rhone-Poulenc Rorer International (Holdings) Inc. Compounds having antihypertensive and anti-ischemic properties
SK179899A3 (en) * 1997-07-03 2001-12-03 Du Pont Pharm Co Imidazopyrimidines and imidazopyridines for the treatment of neurological disorders
CA2357760A1 (en) * 1998-12-21 2000-06-29 Walter Rodriguez Process for preparing n6-substituted deaza-adenosine derivatives

Also Published As

Publication number Publication date
KR100571690B1 (ko) 2006-04-18
KR20060002030A (ko) 2006-01-06
NO992795D0 (no) 1999-06-09
KR100510389B1 (ko) 2005-08-31
SI0946550T1 (en) 2005-10-31
AP9901550A0 (en) 1999-06-30
EA001989B1 (ru) 2001-10-22
KR20060002029A (ko) 2006-01-06
AU738581B2 (en) 2001-09-20
EP1609791A1 (en) 2005-12-28
BG63805B1 (bg) 2003-01-31
CN1191251C (zh) 2005-03-02
CN1090630C (zh) 2002-09-11
EP0946550B1 (en) 2005-08-03
DE69733897T2 (de) 2006-06-01
BR9713705A (pt) 2000-05-09
HK1051862A1 (en) 2003-08-22
HUP0000342A3 (en) 2001-01-29
WO1998025921A1 (en) 1998-06-18
EA199900527A1 (ru) 2000-02-28
US6235909B1 (en) 2001-05-22
HUP0000342A2 (hu) 2000-10-28
NO20052327L (no) 1999-08-10
AP1063A (en) 2002-04-26
CN1240445A (zh) 2000-01-05
NO319722B1 (no) 2005-09-05
AU5360798A (en) 1998-07-03
KR20000057505A (ko) 2000-09-15
SK71199A3 (en) 2000-07-11
DE69733897D1 (de) 2005-09-08
NO992795L (no) 1999-08-10
HK1023998A1 (en) 2000-09-29
EP0946550A1 (en) 1999-10-06
IL130397A0 (en) 2000-06-01
ZA9711035B (en) 1998-06-15
CA2274630C (en) 2000-10-03
CN1394859A (zh) 2003-02-05
ATE301120T1 (de) 2005-08-15
CN1660842A (zh) 2005-08-31
BG103484A (en) 2000-06-30
IL130397A (en) 2005-11-20
EP0946550A4 (en) 2003-05-14
US6143894A (en) 2000-11-07
DK0946550T3 (da) 2005-08-29
KR20050046793A (ko) 2005-05-18
MXPA03006730A (es) 2003-10-24
ES2242984T3 (es) 2005-11-16
PT946550E (pt) 2005-09-30
UA54479C2 (uk) 2003-03-17
JP2001506626A (ja) 2001-05-22
NO20052327D0 (no) 2005-05-12

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