OA10944A - Indoline derivatives useful as 5-ht-2c receptor antagonists - Google Patents
Indoline derivatives useful as 5-ht-2c receptor antagonists Download PDFInfo
- Publication number
- OA10944A OA10944A OA9800245A OA9800245A OA10944A OA 10944 A OA10944 A OA 10944A OA 9800245 A OA9800245 A OA 9800245A OA 9800245 A OA9800245 A OA 9800245A OA 10944 A OA10944 A OA 10944A
- Authority
- OA
- OAPI
- Prior art keywords
- compound according
- formula
- compound
- methyl
- methylpyridin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9612883.0A GB9612883D0 (en) | 1996-06-20 | 1996-06-20 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| OA10944A true OA10944A (en) | 2003-02-27 |
Family
ID=10795575
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| OA9800245A OA10944A (en) | 1996-06-20 | 1998-12-18 | Indoline derivatives useful as 5-ht-2c receptor antagonists |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US6369060B1 (fr) |
| EP (1) | EP0912554B1 (fr) |
| JP (1) | JP2000512306A (fr) |
| KR (1) | KR20000022045A (fr) |
| CN (1) | CN1229408A (fr) |
| AP (2) | AP9801410A0 (fr) |
| AR (1) | AR008243A1 (fr) |
| AT (1) | ATE228514T1 (fr) |
| AU (1) | AU718597B2 (fr) |
| BG (1) | BG103089A (fr) |
| BR (1) | BR9709911A (fr) |
| CA (1) | CA2258240A1 (fr) |
| CO (1) | CO4890847A1 (fr) |
| CZ (1) | CZ420598A3 (fr) |
| DE (1) | DE69717449T2 (fr) |
| DZ (1) | DZ2250A1 (fr) |
| EA (1) | EA001780B1 (fr) |
| ES (1) | ES2187783T3 (fr) |
| GB (1) | GB9612883D0 (fr) |
| HU (1) | HUP9903439A3 (fr) |
| ID (1) | ID19433A (fr) |
| IL (1) | IL127417A0 (fr) |
| MA (1) | MA24214A1 (fr) |
| NO (1) | NO985972L (fr) |
| NZ (1) | NZ333229A (fr) |
| OA (1) | OA10944A (fr) |
| PE (1) | PE86698A1 (fr) |
| PL (1) | PL330796A1 (fr) |
| SK (1) | SK282706B6 (fr) |
| TR (1) | TR199802661T2 (fr) |
| TW (1) | TW382015B (fr) |
| WO (1) | WO1997048699A1 (fr) |
| ZA (1) | ZA975415B (fr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999043650A2 (fr) * | 1998-02-25 | 1999-09-02 | Smithkline Beecham Plc | Procede(s) de preparation de derives de 6-trifluoromethyl-indoline |
| GB0019950D0 (en) * | 2000-08-12 | 2000-09-27 | Smithkline Beecham Plc | Compounds |
| EP1451176A2 (fr) * | 2001-11-28 | 2004-09-01 | PHARMACIA & UPJOHN COMPANY | Derives de benzazepine et leur utilisation comme ligands 5-ht |
| JP2006506319A (ja) * | 2002-03-04 | 2006-02-23 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | ５−ｈｔ受容体リガンドとしてのピリジニルオキシ誘導体 |
| KR101062376B1 (ko) * | 2008-04-10 | 2011-09-06 | 한국화학연구원 | 신규 인돌 카르복실산 비스피리딜 카르복사마이드 유도체,이의 제조방법 및 이를 유효성분으로 함유하는 조성물 |
| EP2387611A4 (fr) | 2009-01-16 | 2012-08-15 | Massachusetts Inst Technology | Diagnostic et traitement de troubles du spectre autistique |
| ES2847883T3 (es) | 2010-12-17 | 2021-08-04 | Glaxo Group Ltd | Uso de inhibidores de LP-PLA2 en el tratamiento y prevención de enfermedades oculares |
| WO2014046544A1 (fr) | 2012-09-21 | 2014-03-27 | Aapa B.V. | 3-hétéroaryloxy-3-(hétéro)aryl-propylamines substituées comme modulateurs de transporteur de la sérotonine et du récepteur ht2c de la sérotonine |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1989001333A1 (fr) | 1987-08-07 | 1989-02-23 | The Australian National University | IMIDAZO[1,2-b]PYRIDAZINES |
| EP0656003A1 (fr) * | 1992-08-20 | 1995-06-07 | Smithkline Beecham Plc | DERIVES D'INDOLE CONDENSES UTILISES COMME ANTAGONISTES DES RECEPTEURS 5HT2C et 5HT2B |
| GB9313913D0 (en) * | 1993-07-06 | 1993-08-18 | Smithkline Beecham Plc | Novel compounds |
| SI0808312T1 (fr) * | 1995-02-02 | 2001-02-28 | Smithkline Beecham Plc | |
| GB9607219D0 (en) * | 1996-04-04 | 1996-06-12 | Smithkline Beecham Plc | Novel compounds |
| GB9615767D0 (en) * | 1996-07-26 | 1996-09-04 | Smithkline Beecham Plc | Novel treatment |
-
1996
- 1996-06-20 GB GBGB9612883.0A patent/GB9612883D0/en active Pending
-
1997
- 1997-06-16 ES ES97928224T patent/ES2187783T3/es not_active Expired - Lifetime
- 1997-06-16 SK SK1752-98A patent/SK282706B6/sk unknown
- 1997-06-16 US US09/202,780 patent/US6369060B1/en not_active Expired - Fee Related
- 1997-06-16 HU HU9903439A patent/HUP9903439A3/hu unknown
- 1997-06-16 BR BR9709911A patent/BR9709911A/pt unknown
- 1997-06-16 CZ CZ984205A patent/CZ420598A3/cs unknown
- 1997-06-16 EP EP97928224A patent/EP0912554B1/fr not_active Expired - Lifetime
- 1997-06-16 CA CA002258240A patent/CA2258240A1/fr not_active Abandoned
- 1997-06-16 PL PL97330796A patent/PL330796A1/xx unknown
- 1997-06-16 KR KR1019980710443A patent/KR20000022045A/ko not_active Application Discontinuation
- 1997-06-16 AP APAP/P/1998/001410A patent/AP9801410A0/en unknown
- 1997-06-16 JP JP10502259A patent/JP2000512306A/ja active Pending
- 1997-06-16 TR TR1998/02661T patent/TR199802661T2/xx unknown
- 1997-06-16 AU AU32602/97A patent/AU718597B2/en not_active Ceased
- 1997-06-16 EA EA199900043A patent/EA001780B1/ru not_active IP Right Cessation
- 1997-06-16 NZ NZ333229A patent/NZ333229A/xx unknown
- 1997-06-16 DE DE69717449T patent/DE69717449T2/de not_active Expired - Fee Related
- 1997-06-16 WO PCT/EP1997/003156 patent/WO1997048699A1/fr not_active Application Discontinuation
- 1997-06-16 IL IL12741797A patent/IL127417A0/xx unknown
- 1997-06-16 CN CN97197311A patent/CN1229408A/zh active Pending
- 1997-06-16 AT AT97928224T patent/ATE228514T1/de not_active IP Right Cessation
- 1997-06-18 DZ DZ970100A patent/DZ2250A1/fr active
- 1997-06-18 AR ARP970102673A patent/AR008243A1/es unknown
- 1997-06-18 AP APAP/P/1997/001037A patent/AP745A/en active
- 1997-06-18 PE PE1997000510A patent/PE86698A1/es not_active Application Discontinuation
- 1997-06-18 MA MA24666A patent/MA24214A1/fr unknown
- 1997-06-19 TW TW086108551A patent/TW382015B/zh not_active IP Right Cessation
- 1997-06-19 ZA ZA975415A patent/ZA975415B/xx unknown
- 1997-06-20 CO CO97034431A patent/CO4890847A1/es unknown
- 1997-06-20 ID IDP972126A patent/ID19433A/id unknown
-
1998
- 1998-12-18 OA OA9800245A patent/OA10944A/en unknown
- 1998-12-18 NO NO985972A patent/NO985972L/no unknown
-
1999
- 1999-01-15 BG BG103089A patent/BG103089A/xx unknown
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