OA10895A - Chimeric isoprenoid synthases and uses thereof - Google Patents

Chimeric isoprenoid synthases and uses thereof Download PDF

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Publication number
OA10895A
OA10895A OA9800191A OA9800191A OA10895A OA 10895 A OA10895 A OA 10895A OA 9800191 A OA9800191 A OA 9800191A OA 9800191 A OA9800191 A OA 9800191A OA 10895 A OA10895 A OA 10895A
Authority
OA
OAPI
Prior art keywords
synthase
chimeric
isoprenoid
isoprenoid synthase
domain
Prior art date
Application number
OA9800191A
Other languages
English (en)
Inventor
Joseph Chappell
Original Assignee
Univ Kentucky
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kentucky filed Critical Univ Kentucky
Publication of OA10895A publication Critical patent/OA10895A/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Physics & Mathematics (AREA)
  • Nutrition Science (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
OA9800191A 1996-04-12 1998-10-09 Chimeric isoprenoid synthases and uses thereof OA10895A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/631,341 US5824774A (en) 1996-04-12 1996-04-12 Chimeric isoprenoid synthases and uses thereof

Publications (1)

Publication Number Publication Date
OA10895A true OA10895A (en) 2001-10-11

Family

ID=24530791

Family Applications (1)

Application Number Title Priority Date Filing Date
OA9800191A OA10895A (en) 1996-04-12 1998-10-09 Chimeric isoprenoid synthases and uses thereof

Country Status (26)

Country Link
US (2) US5824774A (xx)
EP (2) EP0904095B1 (xx)
JP (4) JP2000508899A (xx)
KR (1) KR20000005385A (xx)
AP (1) AP808A (xx)
AR (1) AR006638A1 (xx)
AT (1) ATE223225T1 (xx)
AU (1) AU2726497A (xx)
BR (1) BR9708650A (xx)
CA (1) CA2250712C (xx)
CZ (1) CZ294613B6 (xx)
DE (2) DE904095T1 (xx)
EA (1) EA001622B1 (xx)
ES (1) ES2132046T3 (xx)
GR (1) GR990300025T1 (xx)
HK (1) HK1017275A1 (xx)
ID (1) ID19769A (xx)
IL (2) IL126486A0 (xx)
IN (1) IN186316B (xx)
OA (1) OA10895A (xx)
PL (1) PL329404A1 (xx)
PT (1) PT904095E (xx)
TR (1) TR199802043T2 (xx)
TW (1) TW509724B (xx)
WO (1) WO1997038703A1 (xx)
ZA (1) ZA973108B (xx)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8106260B2 (en) * 1996-04-12 2012-01-31 The Board Of Trustees Of The University Of Kentucky Chimeric isoprenoid synthases and uses thereof
US5824774A (en) * 1996-04-12 1998-10-20 Board Of Trustees Of The University Of Kentucky Chimeric isoprenoid synthases and uses thereof
US7186891B1 (en) * 1996-04-12 2007-03-06 University Of Kentucky, Research Foundation Plant cells and plants expressing chimeric isoprenoid synthases
US5945726A (en) * 1996-12-16 1999-08-31 Micron Technology, Inc. Lateral bipolar transistor
AR022383A1 (es) 1998-09-18 2002-09-04 Univ Kentucky Res Found Sintasas
US6358712B1 (en) 1999-01-05 2002-03-19 Trustee Of Boston University Ordered gene assembly
CA2360011A1 (en) * 1999-01-05 2000-07-13 Trustees Of Boston University Ordered gene assembly
US20040005673A1 (en) * 2001-06-29 2004-01-08 Kevin Jarrell System for manipulating nucleic acids
WO2002010398A2 (en) 2000-07-31 2002-02-07 Hahn Frederick M Manipulation of genes of the mevalonate and isoprenoid pathways to create novel traits in transgenic organisms
AU2002244262B2 (en) 2001-03-09 2007-07-12 University Of Kentucky Research Foundation Cytochrome P450s and uses thereof
AU2013204829B2 (en) * 2001-03-09 2013-07-04 University Of Kentucky Research Foundation Cytochrome P450s and uses thereof
AU2012202780B2 (en) * 2001-03-09 2014-07-03 University Of Kentucky Research Foundation Cytochrome P450s and Uses Thereof
US7172886B2 (en) * 2001-12-06 2007-02-06 The Regents Of The University Of California Biosynthesis of isopentenyl pyrophosphate
US7192751B2 (en) * 2001-12-06 2007-03-20 The Regents Of The University Of California Biosynthesis of amorpha-4,11-diene
US7442785B2 (en) * 2003-07-24 2008-10-28 The University Of Kentucky Research Foundation Sesquiterpene synthase gene and protein
US8124811B2 (en) 2007-03-20 2012-02-28 Allylix, Inc. Fragrance and methods for production of 5-epi-β-vetivone, 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-2,6-dien-8-one, and 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-1,6-dien-8-one
EP2463370B1 (en) 2007-06-01 2013-07-31 Sapphire Energy, Inc. Use of genetically modified organisms to generate biomass degrading enzymes
EP2203542A1 (en) 2007-09-11 2010-07-07 Sapphire Energy, Inc. Methods of producing organic products with photosynthetic organisms and products and compositions thereof
GB2463543A (en) * 2007-09-11 2010-03-24 Sapphire Energy Inc Molecule production by photosynthetic organisms
SG191671A1 (en) * 2007-12-13 2013-07-31 Danisco Us Inc Cultured cells that produce isoprene and methods for producing isoprene
US8034992B2 (en) * 2008-06-16 2011-10-11 Academia Sinica Gibberellin 2-oxidase genes and uses thereof
WO2010019696A2 (en) 2008-08-12 2010-02-18 Allylix, Inc. Method for production of isoprenoids
CN103282492A (zh) 2010-10-29 2013-09-04 奥利里克斯股份有限公司 修饰的瓦伦烯合酶多肽、编码核酸分子及其用途
US9550815B2 (en) 2012-01-23 2017-01-24 University Of British Columbia ABC terpenoid transporters and methods of using the same
JP5950253B2 (ja) * 2012-02-13 2016-07-13 住友ゴム工業株式会社 イソプレノイドの製造方法、及びイソプレノイド
EP3929289A1 (en) 2012-07-30 2021-12-29 Evolva, Inc. Sclareol and labdenediol diphosphate synthase polypeptides, encoding nucleic acid molecules and uses thereof
ES2911701T3 (es) 2012-11-01 2022-05-20 Univ British Columbia Polipéptidos de citocromo P450 y citocromo P450 reductasa, moléculas de ácido nucleico codificantes y usos de los mismos
EP2970934B1 (en) 2013-03-14 2017-08-16 Evolva, Inc. Valencene synthase polypeptides, encoding nucleic acid molecules and uses thereof
CN111621508B (zh) * 2020-06-11 2022-07-01 云南中烟工业有限责任公司 烟草萜类合成酶NtTPS7基因及其载体与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6449794A (en) * 1993-04-02 1994-10-24 Pioneer Hi-Bred International, Inc. Southern corn rootworm control with limonene
CA2118071C (en) * 1993-10-28 2004-09-14 Rodney B. Croteau Dna encoding limonene synthase from mentha spicata
US5824774A (en) * 1996-04-12 1998-10-20 Board Of Trustees Of The University Of Kentucky Chimeric isoprenoid synthases and uses thereof

Also Published As

Publication number Publication date
JP2015057074A (ja) 2015-03-26
JP2012005499A (ja) 2012-01-12
IL126486A (en) 2006-04-10
DE69715192D1 (de) 2002-10-10
CZ317998A3 (cs) 1999-02-17
HK1017275A1 (en) 1999-11-19
JP2015171387A (ja) 2015-10-01
IL126486A0 (en) 1999-08-17
CZ294613B6 (cs) 2005-02-16
EP1229122A2 (en) 2002-08-07
US6072045A (en) 2000-06-06
AR006638A1 (es) 1999-09-08
AU2726497A (en) 1997-11-07
CA2250712A1 (en) 1997-10-23
EP0904095A4 (en) 1999-07-07
WO1997038703A1 (en) 1997-10-23
ID19769A (id) 1998-07-30
EP0904095B1 (en) 2002-09-04
EA199800917A1 (ru) 1999-04-29
ATE223225T1 (de) 2002-09-15
ZA973108B (en) 1997-11-04
DE904095T1 (de) 1999-10-07
TW509724B (en) 2002-11-11
ES2132046T3 (es) 2003-03-16
ES2132046T1 (es) 1999-08-16
AP9700971A0 (en) 1997-07-31
PL329404A1 (en) 1999-03-29
EP0904095A1 (en) 1999-03-31
GR990300025T1 (en) 1999-07-30
DE69715192T2 (de) 2003-04-30
IN186316B (xx) 2001-08-04
EA001622B1 (ru) 2001-06-25
CA2250712C (en) 2008-07-08
EP1229122A3 (en) 2002-10-09
PT904095E (pt) 2002-12-31
US5824774A (en) 1998-10-20
JP2000508899A (ja) 2000-07-18
KR20000005385A (ko) 2000-01-25
BR9708650A (pt) 1999-08-03
AP808A (en) 2000-02-29
TR199802043T2 (xx) 1999-01-18

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