OA10287A - 2- (Pyrazol-3-yl) carbapenem derivatives - Google Patents
2- (Pyrazol-3-yl) carbapenem derivatives Download PDFInfo
- Publication number
- OA10287A OA10287A OA60822A OA60822A OA10287A OA 10287 A OA10287 A OA 10287A OA 60822 A OA60822 A OA 60822A OA 60822 A OA60822 A OA 60822A OA 10287 A OA10287 A OA 10287A
- Authority
- OA
- OAPI
- Prior art keywords
- carbapen
- carboxylate
- sodium
- group
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/14—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939322284A GB9322284D0 (en) | 1993-10-29 | 1993-10-29 | Novel compounds |
| GB9410929A GB9410929D0 (en) | 1994-06-01 | 1994-06-01 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| OA10287A true OA10287A (en) | 1997-10-07 |
Family
ID=26303758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| OA60822A OA10287A (en) | 1993-10-29 | 1996-04-26 | 2- (Pyrazol-3-yl) carbapenem derivatives |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5612477A (de) |
| EP (1) | EP0725783B1 (de) |
| JP (1) | JP3703146B2 (de) |
| KR (1) | KR960705827A (de) |
| CN (1) | CN1167486A (de) |
| AP (1) | AP9600800A0 (de) |
| AT (1) | ATE229957T1 (de) |
| AU (1) | AU697108B2 (de) |
| BG (1) | BG100551A (de) |
| BR (1) | BR9407889A (de) |
| CA (1) | CA2175054C (de) |
| CZ (1) | CZ122996A3 (de) |
| DE (1) | DE69431919T2 (de) |
| ES (1) | ES2188621T3 (de) |
| FI (1) | FI961817A (de) |
| HU (1) | HUT75519A (de) |
| NO (1) | NO961654L (de) |
| NZ (1) | NZ274878A (de) |
| OA (1) | OA10287A (de) |
| PL (1) | PL314173A1 (de) |
| SK (1) | SK53696A3 (de) |
| WO (1) | WO1995011905A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020147333A1 (en) | 1993-10-29 | 2002-10-10 | Smithkline Beecham P.L.C. | 2-(pyrazol-3-yl)carbapenem derivatives |
| EP0785937A1 (de) * | 1994-10-14 | 1997-07-30 | Smithkline Beecham Plc | 2-(imidazol-4-yl)carbapenemderivate, ihre zwischenprodukte und verwendung als antibakterielle mittel |
| MX9708422A (es) * | 1995-05-03 | 1998-02-28 | Smithkline Beecham Plc | Esteres de carbapenemas. |
| IL118092A0 (en) * | 1995-05-03 | 1996-09-12 | Smithkline Beecham Plc | Antibacterial compounds their preparation and pharmaceutical compositions containing them |
| GB0400329D0 (en) * | 2004-01-08 | 2004-02-11 | Glaxo Group Ltd | Novel processes |
| GB0400405D0 (en) * | 2004-01-09 | 2004-02-11 | Glaxo Group Ltd | Novel processes |
| JP2007039383A (ja) * | 2005-08-03 | 2007-02-15 | Dainippon Sumitomo Pharma Co Ltd | アリールカルバペネム化合物の製造方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1593524A (en) * | 1976-11-19 | 1981-07-15 | Merck & Co Inc | 1-carba-2-penem-3-carboxylic acids |
| US4260627A (en) * | 1978-10-24 | 1981-04-07 | Merck & Co., Inc. | 1-, 6- And 2-substituted-1-carba-2-penem-3-carboxylic acids |
| EP0430037A3 (en) * | 1989-11-21 | 1992-05-27 | Banyu Pharmaceutical Co., Ltd. | Process for producing 2-carbon-substituted carbapenem derivatives |
| CA2036960A1 (en) * | 1990-02-26 | 1991-08-27 | Thomas A. Rano | Novel synthesis of carbapenem intermediates |
| JP3233434B2 (ja) * | 1992-04-01 | 2001-11-26 | 塩野義製薬株式会社 | カルバペネム誘導体 |
-
1994
- 1994-10-25 NZ NZ274878A patent/NZ274878A/en unknown
- 1994-10-25 HU HU9601097A patent/HUT75519A/hu unknown
- 1994-10-25 SK SK536-96A patent/SK53696A3/sk unknown
- 1994-10-25 AP APAP/P/1996/000800A patent/AP9600800A0/en unknown
- 1994-10-25 BR BR9407889A patent/BR9407889A/pt not_active Application Discontinuation
- 1994-10-25 WO PCT/GB1994/002347 patent/WO1995011905A1/en active IP Right Grant
- 1994-10-25 AT AT94931092T patent/ATE229957T1/de not_active IP Right Cessation
- 1994-10-25 DE DE69431919T patent/DE69431919T2/de not_active Expired - Fee Related
- 1994-10-25 KR KR1019960702285A patent/KR960705827A/ko not_active Application Discontinuation
- 1994-10-25 PL PL94314173A patent/PL314173A1/xx unknown
- 1994-10-25 EP EP94931092A patent/EP0725783B1/de not_active Expired - Lifetime
- 1994-10-25 CZ CZ961229A patent/CZ122996A3/cs unknown
- 1994-10-25 CN CN94194676A patent/CN1167486A/zh active Pending
- 1994-10-25 CA CA002175054A patent/CA2175054C/en not_active Expired - Fee Related
- 1994-10-25 ES ES94931092T patent/ES2188621T3/es not_active Expired - Lifetime
- 1994-10-25 AU AU79975/94A patent/AU697108B2/en not_active Ceased
- 1994-10-25 JP JP51247795A patent/JP3703146B2/ja not_active Expired - Fee Related
-
1995
- 1995-06-01 US US08/457,002 patent/US5612477A/en not_active Expired - Lifetime
-
1996
- 1996-04-25 NO NO961654A patent/NO961654L/no not_active Application Discontinuation
- 1996-04-26 OA OA60822A patent/OA10287A/en unknown
- 1996-04-29 BG BG100551A patent/BG100551A/xx unknown
- 1996-04-29 FI FI961817A patent/FI961817A/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU697108B2 (en) | 1998-09-24 |
| JPH09504285A (ja) | 1997-04-28 |
| KR960705827A (ko) | 1996-11-08 |
| CZ122996A3 (en) | 1996-10-16 |
| FI961817A (fi) | 1996-06-28 |
| NZ274878A (en) | 1998-02-26 |
| AU7997594A (en) | 1995-05-22 |
| CN1167486A (zh) | 1997-12-10 |
| NO961654D0 (no) | 1996-04-25 |
| PL314173A1 (en) | 1996-08-19 |
| JP3703146B2 (ja) | 2005-10-05 |
| WO1995011905A1 (en) | 1995-05-04 |
| EP0725783B1 (de) | 2002-12-18 |
| ES2188621T3 (es) | 2003-07-01 |
| US5612477A (en) | 1997-03-18 |
| ATE229957T1 (de) | 2003-01-15 |
| HU9601097D0 (en) | 1996-07-29 |
| DE69431919T2 (de) | 2003-11-13 |
| EP0725783A1 (de) | 1996-08-14 |
| CA2175054A1 (en) | 1995-05-04 |
| SK53696A3 (en) | 1996-10-02 |
| FI961817A0 (fi) | 1996-04-29 |
| AP9600800A0 (en) | 1996-04-30 |
| HUT75519A (en) | 1997-05-28 |
| BR9407889A (pt) | 1996-10-29 |
| DE69431919D1 (de) | 2003-01-30 |
| NO961654L (no) | 1996-06-11 |
| CA2175054C (en) | 2005-07-12 |
| BG100551A (en) | 1997-01-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2792103B2 (ja) | ３―ピロリジニルチオ―１―アザビシクロ［３．２．０］ヘプト―２―エン―２―カルボン酸化合物 | |
| US5004739A (en) | 2-phenanthrenyl carbapenem antibacterial agents | |
| WO2000006581A1 (fr) | Nouveaux derives de carbapenem | |
| OA10287A (en) | 2- (Pyrazol-3-yl) carbapenem derivatives | |
| WO2002040483A1 (fr) | Dérivés 1-méthylcarbapenem | |
| JPH10507185A (ja) | ２−（イミダゾール−４−イル）カルバペネム誘導体、その中間体および抗菌剤としての使用 | |
| US5606051A (en) | 2-(pyrazol-3-yl)carbapenem derivatives | |
| JPS6222786A (ja) | 複素環メチレンペネム化合物、その製造法および抗菌組成物 | |
| US7045619B2 (en) | 2-(pyrazol-3-yl)carbapenem derivatives | |
| JPH05105681A (ja) | ２−（９−フルオレノニル）−カルバペネム | |
| US5384317A (en) | Bridged biphenyl carbapenem compounds, compositions containing such compounds and methods of use | |
| US5116833A (en) | Antibiotic c-3 dithioacetal-substituted carbapenem compounds, compositions, and methods of use thereof | |
| MXPA97008422A (en) | Carbapene steres | |
| EP0337643A2 (de) | 6-Substituierte Acrylamido-Penizillansäure-Derivate, Herstellung und Verwendung | |
| WO1996034869A1 (en) | Esters of carbapenems | |
| JP2002212182A (ja) | １−メチルカルバペネム誘導体 | |
| IE921546A1 (en) | Chemical compounds | |
| US5372993A (en) | Bridged carbapenem compounds, compositions containing such compounds and methods of use | |
| JPH09503518A (ja) | ３−ピロリジニルチオ−カルバペネム誘導体およびそれらの抗菌活性 | |
| WO1996034868A1 (en) | Esters of carbapenems | |
| JPH05105680A (ja) | ２−フエナントレニルカルバペネム類 | |
| JPH05213955A (ja) | （ｎ−ピリジニウムフェニル）−カルバペネム | |
| JPH04234886A (ja) | １−アザビシクロ［３．２．０］ヘプト−２−エン−２−カルボン酸化合物 | |
| JPH0242081A (ja) | ３―ピロリジニオチオ‐１‐アザビシクロ［３．２．０．］ヘプト‐２‐エン‐２‐カルボキシレート化合物およびその製造方法 |