OA03446A - Procédé de préparation de nouvelles 6-phényl-4H-s-triazolo [4,3-a][1,4]-benzodiazépines. - Google Patents

Procédé de préparation de nouvelles 6-phényl-4H-s-triazolo [4,3-a][1,4]-benzodiazépines.

Info

Publication number
OA03446A
OA03446A OA53877A OA53877A OA03446A OA 03446 A OA03446 A OA 03446A OA 53877 A OA53877 A OA 53877A OA 53877 A OA53877 A OA 53877A OA 03446 A OA03446 A OA 03446A
Authority
OA
OAPI
Prior art keywords
benzodiazepines
triazolo
phenyl
novel
preparation
Prior art date
Application number
OA53877A
Other languages
English (en)
Inventor
Jackson Boling Hester Jr
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27123060&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=OA03446(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of OA03446A publication Critical patent/OA03446A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/20—Nitrogen atoms
OA53877A 1969-03-17 1970-03-16 Procédé de préparation de nouvelles 6-phényl-4H-s-triazolo [4,3-a][1,4]-benzodiazépines. OA03446A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80793369A 1969-03-17 1969-03-17
US04/872,394 US3987052A (en) 1969-03-17 1969-10-29 6-Phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepines

Publications (1)

Publication Number Publication Date
OA03446A true OA03446A (fr) 1971-03-30

Family

ID=27123060

Family Applications (1)

Application Number Title Priority Date Filing Date
OA53877A OA03446A (fr) 1969-03-17 1970-03-16 Procédé de préparation de nouvelles 6-phényl-4H-s-triazolo [4,3-a][1,4]-benzodiazépines.

Country Status (18)

Country Link
US (1) US3987052A (fr)
JP (1) JPS4940239B1 (fr)
AU (2) AU490626B2 (fr)
BE (1) BE747493A (fr)
BR (1) BR7017488D0 (fr)
CH (1) CH535788A (fr)
DE (1) DE2012190C3 (fr)
ES (1) ES376689A1 (fr)
FR (1) FR2034999A1 (fr)
GB (1) GB1291631A (fr)
HK (1) HK61677A (fr)
IL (1) IL33859A (fr)
NL (2) NL172510C (fr)
OA (1) OA03446A (fr)
PH (1) PH9329A (fr)
PL (1) PL80541B1 (fr)
SE (1) SE387641B (fr)
YU (1) YU35139B (fr)

Families Citing this family (81)

* Cited by examiner, † Cited by third party
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BE779988R (fr) * 1969-03-17 1972-08-29 Upjohn Co Nouvelles 6-phenyl-4h-s-triazolo(4,3-a)(1,4)- benzodiazepines douees d'activite pharmacologique et leur procede de
BE758921A (fr) * 1969-11-15 1971-04-16 Takeda Chemical Industries Ltd Derives de benzodiazepine
BE759099A (fr) * 1969-11-18 1971-04-30 Takeda Chemical Industries Ltd Procede de fabrication de composes heterocycliques
YU34997B (en) * 1970-03-27 1980-06-30 Hiroyuki Tawada Process for preparing benzodiazepine derivatives
DE2156472A1 (de) * 1970-11-23 1972-05-31 Ciba-Geigy Ag, Basel (Schweiz) Verfahren zur Herstellung von neuen Diazepinderivaten
CH544764A (de) * 1971-01-21 1974-01-15 Ciba Geigy Ag Verfahren zur Herstellung von neuen Triazolo-benzodiazepinderivaten
US3709898A (en) * 1971-02-09 1973-01-09 Upjohn Co Process for the production of triazolobenzodiazepines and intermediates
YU36376B (en) * 1971-03-03 1983-06-30 Upjohn Co Process for producing dihalo-6-phenyltriazolobenzodiazepine-5-n-oxide
DE2164777A1 (de) * 1971-03-03 1972-09-07 Upjohn Co 8-Nitro-6-(o-halogenphenyl)-l-methyl-4H-s-triazolo eckige Klammer auf 4,3-a eckige Klammer zu-eckige Klammer auf 1-4 eckige Klammer zu benzodiazepine und diese enthaltende pharmazeutische Präparate
DE2164778C2 (de) * 1971-03-03 1984-07-05 The Upjohn Co., Kalamazoo, Mich. 6-(o-Chlorphenyl)-1-methyl-4H-s-triazolo[4,3-a][1,4]-benzodiazepin und dieses enthaltende pharmazeutische Präparat
CH545302A (de) * 1971-04-08 1974-01-13 Ciba Geigy Ag Verfahren zur Herstellung von neuen Triazolo-benzodiazepinderivaten
US4141902A (en) 1971-04-28 1979-02-27 The Upjohn Company 1-Halomethyl-6-phenyl-4H-s-[4,3-a][1,4]benzodiazepines
GB1331015A (en) * 1971-04-28 1973-09-19 Upjohn Co 1-substituted-6-phenyl-4h-s-triazolo-4,3-a-1,4-benzodiazepines
US3759943A (en) * 1971-04-28 1973-09-18 Upjohn Co Amido and amino triazolo benzodiazepines
US3709899A (en) 1971-04-28 1973-01-09 Upjohn Co 6-phenyl-4h-s-triazolo(4,3-a)(1,4)benzodiazepines and their production
GB1323277A (en) * 1971-05-10 1973-07-11 Upjohn Co Triazolobenzodiazepines
US3734922A (en) * 1971-05-11 1973-05-22 Upjohn Co Certain 4h-s-triazolo(4,3-a)(1,4)benzodiazepines
US4000289A (en) * 1971-07-08 1976-12-28 The Upjohn Company Animal feed and process
BE787251A (fr) * 1971-08-04 1973-02-05 Upjohn Co Nouvelles benzodiazepines et leur preparation
US3870793A (en) * 1971-08-09 1975-03-11 Upjohn Co Animal feed and process
GB1373300A (en) * 1971-09-08 1974-11-06 Upjohn Co Triazolobenzodiazepines and the manufacture thereof
GB1381158A (en) * 1971-09-13 1975-01-22 Upjohn Co Benzodiazepines and the manufacture thereof
US3767661A (en) * 1971-09-13 1973-10-23 Upjohn Co 4h-s-triazolo(4,3-a)(1,4)benzodiazepines
US3714178A (en) * 1971-09-30 1973-01-30 Upjohn Co 6,7-DIHYDRO-7-ALKYL-5H-1,2,4-TRIAZOLO[4,3-d][1,4]BENZODIAZEPINES AND THEIR PRODUCTION
BE790838A (fr) * 1971-11-02 1973-04-30 Upjohn Co Nouvelles 1-aminophenyl-6-phenyl-s-triazolo (4,3-a) (1,4)- benzodiazepines, leur procede de preparation et medicament les contenant
FI53821C (fi) * 1971-11-15 1978-08-10 Ciba Geigy Ag Foerfarande foer framstaellning av farmakologiskt vaerdefull 6-fenyl-8-klor-4h-s-triazolo(4 3-a)(1 4)bensodiazepin-1-metanol
FR2128552A2 (en) * 1972-03-02 1972-10-20 Upjohn Co S-triazolo (4,3-a) (1,4) benzodiazepines - as anxiolytic agents, muscle relaxants
CH572056A5 (fr) * 1972-11-28 1976-01-30 Ciba Geigy Ag
CH579083A5 (fr) * 1972-12-29 1976-08-31 Ciba Geigy Ag
US4978753A (en) * 1973-01-15 1990-12-18 The Upjohn Company 7-phenylpyrimido[1,2-alpha][1,4]benzodiazepin-3(5H)-ones
US4082761A (en) * 1973-09-04 1978-04-04 The Upjohn Company Triazolo[4,3-a][1,4]benzodiazepinium quaternary salts
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US4431589A (en) * 1980-12-11 1984-02-14 Lilly House Benzodiazepine compounds and their use as pharmaceuticals
US4455307A (en) * 1982-01-04 1984-06-19 The Upjohn Company Antihypertensive use of triazolobenzodiazepines
US4375473A (en) * 1982-01-04 1983-03-01 The Upjohn Company Method
DE3332830A1 (de) * 1982-09-16 1984-03-22 The Upjohn Co., 49001 Kalamazoo, Mich. Verwendung von benzodiazepinen zur bekaempfung oder bei der behandlung von panikzustaenden
US4508726A (en) * 1982-09-16 1985-04-02 The Upjohn Company Treatment of panic disorders with alprazolam
US4481208A (en) * 1983-06-06 1984-11-06 The Upjohn Company Treatment of panic disorders with estazolam
US4514407A (en) * 1983-03-17 1985-04-30 The Upjohn Company 1-Ethanamine-triazolo-benzodiazepines as diuretics
US4689413A (en) * 1983-03-17 1987-08-25 The Upjohn Company Triazolo-benzodiazepine-1-ethanamines as diuretics
US4474699A (en) * 1983-05-25 1984-10-02 The Upjohn Company Preparing 1-aminomethyl-6-substituted-4H-s-triazolo[4,3-a][1,4]benzodiazepines in improved procedures
US4588721A (en) * 1983-09-12 1986-05-13 The Upjohn Company Treatment of negative symptoms of schizophrenia
US4547499A (en) * 1984-05-10 1985-10-15 The Upjohn Company 2,4-Dihydro-2(omega-aminoalkyl)-1H-[1,2,4]triazolo[3,4-c]benzoxazin-1-one anti-allergy drug compounds, compositions and use
US4634703A (en) * 1985-10-25 1987-01-06 Bristol-Myers Company Method for alleviation of panic disorders
US4959361A (en) * 1987-12-18 1990-09-25 Hoffmann-La Roche Inc. Triazolo(4,3-A)(1,4)benzodiazepines and thieno (3,2-F)(1,2,4)triazolo(4,3-A)(1,4)diazepine compounds which have useful activity as platelet activating factor (PAF) antagonists
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US4856303A (en) * 1988-07-21 1989-08-15 Whirlpool Corporation Agitator thrust spacer for automatic washer
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Also Published As

Publication number Publication date
FR2034999A1 (fr) 1970-12-18
PH9329A (en) 1975-09-23
NL172510C (nl) 1983-09-16
GB1291631A (en) 1972-10-04
JPS4940239B1 (fr) 1974-10-31
NL7003750A (nl) 1970-09-21
AU8550075A (en) 1975-12-18
YU35139B (en) 1980-09-25
NL170857B (nl) 1982-08-02
DE2012190A1 (de) 1970-09-24
US3987052A (en) 1976-10-19
AU491139B2 (en) 1975-12-18
NL172510B (nl) 1983-04-18
YU34570A (en) 1979-04-30
NL170857C (nl) 1983-01-03
AU490626B2 (en) 1975-12-18
CH535788A (de) 1973-04-15
IL33859A0 (en) 1970-04-20
IL33859A (en) 1973-01-30
ES376689A1 (es) 1972-05-01
SE387641B (sv) 1976-09-13
HK61677A (en) 1977-12-23
BE747493A (fr) 1970-09-17
PL80541B1 (pl) 1975-08-30
AU8549975A (en) 1975-12-18
DE2012190C3 (de) 1980-11-13
BR7017488D0 (pt) 1973-02-13
DE2012190B2 (de) 1980-03-06
FR2034999B1 (fr) 1973-07-13
NL8100081A (nl) 1981-04-29

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