OA01363A - Procédé de préparation de dérivés de diphényl-méthane portant des substituants basiques. - Google Patents
Procédé de préparation de dérivés de diphényl-méthane portant des substituants basiques.Info
- Publication number
- OA01363A OA01363A OA51809A OA51809A OA01363A OA 01363 A OA01363 A OA 01363A OA 51809 A OA51809 A OA 51809A OA 51809 A OA51809 A OA 51809A OA 01363 A OA01363 A OA 01363A
- Authority
- OA
- OAPI
- Prior art keywords
- diphenyl
- preparation
- methane derivatives
- derivatives bearing
- basic substituents
- Prior art date
Links
- 229940054021 anxiolytics diphenylmethane derivative Drugs 0.000 title 1
- 125000006840 diphenylmethane group Chemical group 0.000 title 1
- 125000001424 substituent group Chemical group 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEF25702A DE1111642B (de) | 1958-05-07 | 1958-05-07 | Verfahren zur Herstellung von basisch substituierten Diphenylmethan-Derivaten mit Herz- und Kreislaufwirksamkeit |
Publications (1)
Publication Number | Publication Date |
---|---|
OA01363A true OA01363A (fr) | 1969-07-04 |
Family
ID=7091732
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
OA51809A OA01363A (fr) | 1958-05-07 | 1964-12-31 | Procédé de préparation de dérivés de diphényl-méthane portant des substituants basiques. |
Country Status (10)
Country | Link |
---|---|
US (1) | US3152173A (en:Method) |
BE (1) | BE578515A (en:Method) |
CH (8) | CH388333A (en:Method) |
CY (1) | CY277A (en:Method) |
DE (1) | DE1111642B (en:Method) |
FR (1) | FR553M (en:Method) |
GB (1) | GB916644A (en:Method) |
MY (1) | MY6400049A (en:Method) |
NL (2) | NL238796A (en:Method) |
OA (1) | OA01363A (en:Method) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3262977A (en) * | 1962-03-10 | 1966-07-26 | Chinoin Gyogyszer Es Vegyeszet | N-aralkyl-1, 1-diphenyl-propylamine derivatives |
NL296693A (en:Method) * | 1962-08-16 | |||
DK111894A (en:Method) | 1962-11-15 | |||
FR95908E (fr) * | 1963-11-09 | 1972-01-31 | Degussa | Procédé de préparation de nouvelles aminocétones et des alcools secondaires correspondants. |
DE1231704B (de) | 1963-12-19 | 1967-01-05 | Josef Klosa Dipl Chem Dr Rer N | Verfahren zur Herstellung neuer Diaryl-alkylaminoverbindungen mit heterocyclischen Ringen |
US3457354A (en) * | 1965-09-21 | 1969-07-22 | Merck & Co Inc | Treatment of hypertension with 2-hydroxy (or amino) - 4,5 - dihydroxyphenethylamine derivatives |
US3895057A (en) * | 1967-10-13 | 1975-07-15 | Dainippon Pharmaceutical Co | Aminoalkanols and their pharmaceutically acceptable acid-addition salts, and production thereof |
US4329367A (en) * | 1974-08-05 | 1982-05-11 | Ciba-Geigy Corporation | 1-(Aralkoxyphenyl)-2-(bis-arylalkylamino)-alkanes |
DE2902172C2 (de) * | 1979-01-20 | 1984-05-10 | UOP Inc., 60016 Des Plaines, Ill. | Verfahren zur Herstellung eines N,N'-Dialkylphenylendiamins |
ATE33208T1 (de) * | 1982-04-23 | 1988-04-15 | Caola Kozmetikai | Kosmetische zusammensetzungen enthaltend phenylamin und deren herstellung. |
ATE41655T1 (de) * | 1985-04-16 | 1989-04-15 | Hoffmann La Roche | Phenaethanolaminderivate. |
US6982251B2 (en) * | 2000-12-20 | 2006-01-03 | Schering Corporation | Substituted 2-azetidinones useful as hypocholesterolemic agents |
CA2434488A1 (en) * | 2001-01-26 | 2002-08-01 | Harry R. Davis | Combinations of nicotinic acid and derivatives thereof and sterol absorption inhibitor(s) and treatments for vascular indications |
PT1385548E (pt) * | 2001-01-26 | 2007-08-24 | Schering Corp | Combinações de um inibidor ou de inibidores de absorção de esteróis com agente (s) para o tratamento de doenças vasculares |
JP2004521894A (ja) * | 2001-01-26 | 2004-07-22 | シェーリング コーポレイション | 胆汁酸金属イオン封鎖剤およびステロール吸収阻害剤の併用および血管適応症の治療 |
SK287746B6 (sk) * | 2001-01-26 | 2011-08-04 | Schering Corporation | Použitie substituovaných azetidinónových zlúčenín na liečenie sitosterolémie |
US7071181B2 (en) * | 2001-01-26 | 2006-07-04 | Schering Corporation | Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors |
SI1353694T1 (sl) * | 2001-01-26 | 2008-06-30 | Schering Corp | Kombinacije ezetimiba z aspirinom za zdravljenejevaskularnih stanj |
PT1353696E (pt) * | 2001-01-26 | 2007-02-28 | Schering Corp | Combinações de activador (es) do receptor activado por proliferador do peroxisoma (ppar) e inibidor (es) da absorção de esterol e tratamentos para indicações vasculares |
EP1392287B8 (en) * | 2001-05-25 | 2007-01-10 | Schering Corporation | Use of substituted azetidinone derivatives in the treatment of Alzheimer's disease |
US20030119808A1 (en) * | 2001-09-21 | 2003-06-26 | Schering Corporation | Methods of treating or preventing cardiovascular conditions while preventing or minimizing muscular degeneration side effects |
NZ531060A (en) * | 2001-09-21 | 2006-06-30 | Schering Corp | Methods for treating or preventing vascular inflammation using sterol absorption inhibitor(s) |
US7053080B2 (en) * | 2001-09-21 | 2006-05-30 | Schering Corporation | Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors |
US7056906B2 (en) * | 2001-09-21 | 2006-06-06 | Schering Corporation | Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women |
ATE345793T1 (de) * | 2001-09-21 | 2006-12-15 | Schering Corp | Behandlung von xanthom mittels azetidinon- derivate als hemmer der sterol absorption |
HRP20050163A2 (en) | 2002-08-19 | 2005-06-30 | Pfizer Products Inc. | Combination therapy for hyperproliferative diseases |
WO2004043457A1 (en) * | 2002-11-06 | 2004-05-27 | Schering Corporation | Cholesterol absorptions inhibitors for the treatment of autoimmune disorders |
MXPA05009502A (es) * | 2003-03-07 | 2005-10-18 | Schering Corp | Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia. |
MXPA05009501A (es) | 2003-03-07 | 2005-10-18 | Schering Corp | Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia. |
US7459442B2 (en) | 2003-03-07 | 2008-12-02 | Schering Corporation | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
ATE406364T1 (de) | 2003-03-07 | 2008-09-15 | Schering Corp | Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia |
JP2007510659A (ja) * | 2003-11-05 | 2007-04-26 | シェーリング コーポレイション | 脂質調節剤および置換アゼチジノンの組み合わせならびに血管状態の処置 |
JP2008507585A (ja) * | 2004-07-26 | 2008-03-13 | コセリックス インク | 微粒子製剤を用いて吸入したイロプロストによる肺高血圧症の治療 |
US20060063803A1 (en) * | 2004-09-23 | 2006-03-23 | Pfizer Inc | 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds |
US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
EP2351569B1 (en) | 2005-10-26 | 2012-08-22 | Asahi Kasei Pharma Corporation | Fasudil in combination therapies for the treatment of pulmonary arterial hypertension |
JP2009513660A (ja) | 2005-10-26 | 2009-04-02 | 旭化成ファーマ株式会社 | 肺動脈性高血圧の治療用併用療法におけるファスジル |
US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
US7919506B2 (en) | 2006-03-10 | 2011-04-05 | Pfizer Inc. | Dibenzyl amine compounds and derivatives |
US8404896B2 (en) | 2006-12-01 | 2013-03-26 | Bristol-Myers Squibb Company | N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular diseases |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
CN103601792B (zh) | 2007-06-04 | 2016-06-29 | 协同医药品公司 | 有效用于胃肠功能紊乱、炎症、癌症和其他疾病治疗的鸟苷酸环化酶激动剂 |
CA2726917C (en) | 2008-06-04 | 2018-06-26 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
EP2321341B1 (en) | 2008-07-16 | 2017-02-22 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
US8883844B2 (en) | 2010-09-24 | 2014-11-11 | Nitrogenix Inc. | Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions |
US9486494B2 (en) | 2013-03-15 | 2016-11-08 | Synergy Pharmaceuticals, Inc. | Compositions useful for the treatment of gastrointestinal disorders |
CA2905438A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
HK1213886A1 (zh) | 2013-04-17 | 2016-07-15 | 辉瑞大药厂 | 用於治療心血管疾病的n-哌啶-3-基苯甲酰胺衍生物 |
SI3004138T1 (sl) | 2013-06-05 | 2024-07-31 | Bausch Health Ireland Limited | Ultra čisti agonisti gvanilat ciklaze C, postopek za njihovo pripravo in uporabo |
WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
MX2021008533A (es) | 2019-01-18 | 2021-08-19 | Astrazeneca Ab | Inhibidores de la pcsk9 y metodos de uso de los mismos. |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2601323A (en) * | 1949-02-02 | 1952-06-24 | Upjohn Co | Process for preparing 4, 4-diphenyl-6-dimethylamino-heptanone-3 |
US2681934A (en) * | 1950-01-06 | 1954-06-22 | Commercial Solvents Corp | Substituted diphenylalkylamines |
US2797242A (en) * | 1953-08-11 | 1957-06-25 | Parke Davis & Co | Substituted alpha-benzylphenethylamines and methods for producing the same |
US2738347A (en) * | 1954-12-13 | 1956-03-13 | Olin Mathieson | Penicillin salt of benzhydryl-phenethylamine |
US2872374A (en) * | 1955-02-02 | 1959-02-03 | Nat Drug Co | Muscle-relaxing tranquilizer compositions |
US2894033A (en) * | 1955-11-15 | 1959-07-07 | Nl Combinatie Chem Ind | Antispasmodic 1, 1-diphenyl-3-dialkylaminopropane, and its tertiary and quaternary salts |
US2854379A (en) * | 1956-06-06 | 1958-09-30 | Miles Lab | Tranquilizing composition comprising 2-ethyl-cis-crotonylurea |
DE1058063B (de) * | 1957-02-08 | 1959-05-27 | Hoechst Ag | Verfahren zur Herstellung von analgetisch wirksamen substituierten Phenylaethylaminen |
-
0
- NL NL108640D patent/NL108640C/xx active
- NL NL238796D patent/NL238796A/xx unknown
- BE BE578515D patent/BE578515A/xx unknown
-
1958
- 1958-05-07 DE DEF25702A patent/DE1111642B/de active Pending
-
1959
- 1959-05-05 CH CH462864A patent/CH388333A/de unknown
- 1959-05-05 CH CH7291559A patent/CH385878A/de unknown
- 1959-05-05 CH CH463164A patent/CH388328A/de unknown
- 1959-05-05 CH CH463264A patent/CH388329A/de unknown
- 1959-05-05 CH CH462964A patent/CH388334A/de unknown
- 1959-05-05 CH CH462764A patent/CH388332A/de unknown
- 1959-05-05 US US811011A patent/US3152173A/en not_active Expired - Lifetime
- 1959-05-05 CH CH708765A patent/CH397710A/de unknown
- 1959-05-05 CH CH463064A patent/CH396931A/de unknown
- 1959-05-07 GB GB15785/59A patent/GB916644A/en not_active Expired
-
1960
- 1960-08-31 FR FR837345A patent/FR553M/fr not_active Expired
-
1964
- 1964-02-12 CY CY27764A patent/CY277A/xx unknown
- 1964-12-31 OA OA51809A patent/OA01363A/xx unknown
- 1964-12-31 MY MY196449A patent/MY6400049A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
NL108640C (en:Method) | |
CH388329A (de) | 1965-02-28 |
CY277A (en) | 1964-02-12 |
MY6400049A (en) | 1964-12-31 |
US3152173A (en) | 1964-10-06 |
CH388334A (de) | 1965-02-28 |
CH397710A (de) | 1965-08-31 |
BE578515A (en:Method) | |
CH396931A (de) | 1965-08-15 |
CH388328A (de) | 1965-02-28 |
DE1111642B (de) | 1961-07-27 |
GB916644A (en) | 1963-01-23 |
CH388332A (de) | 1965-02-28 |
CH385878A (de) | 1964-12-31 |
CH388333A (de) | 1965-02-28 |
FR553M (en:Method) | 1961-05-29 |
NL238796A (en:Method) |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
OA01363A (fr) | Procédé de préparation de dérivés de diphényl-méthane portant des substituants basiques. | |
FR1229384A (fr) | Procédé de préparation de dérivés de la 2, 3-dimercapto-quinoxaline | |
BE589982A (fr) | Procédé de préparation de dérivés de la phtalimidine. | |
BE591486A (fr) | Procédé pour la préparation de dérivés de 5-fluoro-cytosine. | |
BE579237A (fr) | Procédé de préparation des phosphoramidates. | |
FR1292922A (fr) | Procédé de préparation de dérivés de diphényl-méthane portant des substituants basiques | |
FR1309818A (fr) | Procédé de préparation de dérivés de 20-alcoyl-amino-stéroïdes | |
BE583839A (fr) | Procédé de préparation de dérivés quinoniques. | |
FR1238739A (fr) | Procédé de préparation de dérivés hydrosolubles de testostérone | |
FR1481001A (fr) | Procédé de préparation des dérivés de la phénacyl-pipérazine | |
FR1274397A (fr) | Procédé de préparation de dérivés 9alpha-fluoro 16alpha-méthyl delta1, 4-pregnadiènes | |
BE589345A (fr) | Procédé de préparation de dérivés phénothiaziniques. | |
FR1274399A (fr) | Procédé perfectionné de préparation de dérivés du 5-nitro-2-formyl-furan | |
FR1223732A (fr) | Procédé de préparation de dérivés 2-thiono-4-hydroxytétrahydropyrimidines | |
BE577308A (fr) | Procédé de préparation de dérivés du thiaxanthène à substituants basiques. | |
FR1295307A (fr) | Procédé de préparation de dérivés cyclopentano-phénanthréniques | |
FR1404860A (fr) | Procédé de préparation de dérivés de la 5-amino-8-hydroxy-1. 4-naphtoquinone-1-imine portant des substituants basiques | |
FR1294102A (fr) | Procédé de préparation des dérivés azotés de phénylalcanols | |
FR1383702A (fr) | Procédé de préparation de dérivés de la disulfamylaniline | |
FR1330109A (fr) | Procédé de préparation de dérivés de la dichloro-acétanilide | |
CH384582A (fr) | Procédé de préparation de dérivés de la dihydrobenzothiadiazine | |
FR1291508A (fr) | Procédé de préparation de dérivés de la dihydro-vitamine k | |
FR1272913A (fr) | Procédé de préparation des 5-alkyl-2-p-halogénobenzènesulfonamido-1, 3, 4-thiadiazoles | |
FR1298304A (fr) | Procédé de préparation de dérivés de la kanamycine | |
FR1341467A (fr) | Procédé de préparation de dérivés de nu-carboxylalcoyl-2-phényléthylamines |