NZ782911A - Human antibodies to bet v 1 and methods of use thereof - Google Patents

Human antibodies to bet v 1 and methods of use thereof

Info

Publication number
NZ782911A
NZ782911A NZ782911A NZ78291118A NZ782911A NZ 782911 A NZ782911 A NZ 782911A NZ 782911 A NZ782911 A NZ 782911A NZ 78291118 A NZ78291118 A NZ 78291118A NZ 782911 A NZ782911 A NZ 782911A
Authority
NZ
New Zealand
Prior art keywords
antibodies
seq
amino acid
acid sequence
bet
Prior art date
Application number
NZ782911A
Other languages
English (en)
Inventor
Andrew J Murphy
Yashu Liu
Jamie M Orengo
Ashok T Badithe
Vishal Kamat
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of NZ782911A publication Critical patent/NZ782911A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51Complete heavy chain or Fd fragment, i.e. VH + CH1
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/515Complete light chain, i.e. VL + CL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NZ782911A 2017-06-01 2018-05-31 Human antibodies to bet v 1 and methods of use thereof NZ782911A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201762513872P 2017-06-01 2017-06-01
US201762571696P 2017-10-12 2017-10-12
US201862662165P 2018-04-24 2018-04-24
NZ759513A NZ759513A (en) 2017-06-01 2018-05-31 Human antibodies to bet v 1 and methods of use thereof

Publications (1)

Publication Number Publication Date
NZ782911A true NZ782911A (en) 2025-08-29

Family

ID=62705709

Family Applications (2)

Application Number Title Priority Date Filing Date
NZ782911A NZ782911A (en) 2017-06-01 2018-05-31 Human antibodies to bet v 1 and methods of use thereof
NZ759513A NZ759513A (en) 2017-06-01 2018-05-31 Human antibodies to bet v 1 and methods of use thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
NZ759513A NZ759513A (en) 2017-06-01 2018-05-31 Human antibodies to bet v 1 and methods of use thereof

Country Status (17)

Country Link
US (3) US10793624B2 (enExample)
EP (1) EP3630814A1 (enExample)
JP (3) JP6963036B2 (enExample)
KR (3) KR102329175B1 (enExample)
CN (1) CN110997713B (enExample)
AU (2) AU2018275657B2 (enExample)
BR (1) BR112019025150B1 (enExample)
CA (1) CA3063588A1 (enExample)
CL (3) CL2019003508A1 (enExample)
CO (1) CO2019013196A2 (enExample)
IL (2) IL298034B2 (enExample)
MX (2) MX2019014430A (enExample)
MY (1) MY198270A (enExample)
NZ (2) NZ782911A (enExample)
PH (1) PH12019550238A1 (enExample)
WO (1) WO2018222854A1 (enExample)
ZA (1) ZA201907513B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2919934T3 (es) 2017-05-05 2022-07-29 Regeneron Pharma Autoinyector y procedimientos de uso relacionados
AU2018275657B2 (en) * 2017-06-01 2022-01-06 Regeneron Pharmaceuticals, Inc. Human antibodies to Bet v 1 and methods of use thereof
EP4175986A1 (en) * 2020-07-01 2023-05-10 Regeneron Pharmaceuticals, Inc. Methods of treating allergy using anti-bet v 1 antibodies
CN113041271B (zh) * 2021-04-14 2022-12-27 浙江养生堂天然药物研究所有限公司 具有预防和抗过敏功效的组合物
EP4444348A4 (en) * 2021-12-08 2025-12-03 Iggenix Inc COMBINATIONS FOR ALLERGY THERAPY
WO2024200854A1 (en) 2023-03-31 2024-10-03 Alk-Abelló A/S Allergen binding antibodies suitable for treating tree pollen allergies
WO2024251358A1 (en) 2023-06-07 2024-12-12 Mabylon Ag Anti-allergen antibodies and uses thereof
WO2024259313A1 (en) 2023-06-16 2024-12-19 Regeneron Pharamceuticals, Inc. Medical device packaging and related methods
US12319747B2 (en) 2023-07-03 2025-06-03 Medicovestor, Inc. Methods of using anti-SP17 immunotherapeutics
US20250011403A1 (en) * 2023-07-03 2025-01-09 Medicovestor, Inc. Nucleic acids, vectors, and cells that encode anti-sp17 antibodies and other sp17 binding proteins
AR134008A1 (es) 2023-10-02 2025-11-26 Regeneron Pharma Sistema de seguridad de dispositivo de administración de fármaco
US12364777B2 (en) 2023-10-20 2025-07-22 Medicovestor, Inc. Homodimeric antibodies for use in treating cancers and methods of use
US20250255994A1 (en) * 2023-11-29 2025-08-14 Medicovestor, Inc. Dimeric immunoconjugates for use in treating cancers and methods of use
US12116410B1 (en) 2023-12-26 2024-10-15 Medicovestor, Inc. Methods of manufacturing dimeric antibodies
US20250263471A1 (en) 2024-01-30 2025-08-21 Regeneron Pharmaceuticals, Inc. Methods of treating allergy using anti-bet v 1 antibodies

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5411594A (en) 1992-10-27 1994-05-24 Biomay Produktions- Und Handelsgesellschaft M.B.H. Molecule fragments (peptides) of the main allergens contained in the pollen of trees of the (fagales) order
JPH08501799A (ja) 1992-12-21 1996-02-27 タノックス バイオシステムズ インコーポレイテッド アレルゲン特異的IgAモノクローナル抗体及びアレルギー治療のための関連物質
EP0619323A1 (en) 1993-04-09 1994-10-12 Schering-Plough Human monoclonal antibodies and processes and materials for making such antibodies
GB0002386D0 (en) 2000-02-02 2000-03-22 Novartis Nutrition Ag Therapeutic composition
US6849259B2 (en) 2000-06-16 2005-02-01 Symphogen A/S Polyclonal antibody composition for treating allergy
US6596541B2 (en) 2000-10-31 2003-07-22 Regeneron Pharmaceuticals, Inc. Methods of modifying eukaryotic cells
US20040101920A1 (en) 2002-11-01 2004-05-27 Czeslaw Radziejewski Modification assisted profiling (MAP) methodology
EP1740946B1 (en) 2004-04-20 2013-11-06 Genmab A/S Human monoclonal antibodies against cd20
ITMI20052517A1 (it) * 2005-12-29 2007-06-30 Lofarma Spa Varianbtio ipoallergeniche dell'allergene maggiore bet v 1 di polline di betula verrucosa
AT503297B1 (de) * 2006-05-18 2007-09-15 Biomay Ag Allergen-spezifische antikörper
CA2652976C (en) 2006-06-02 2015-08-11 Regeneron Pharmaceuticals, Inc. High affinity antibodies to human il-6 receptor
GB201002559D0 (en) 2010-02-15 2010-03-31 Circassia Ltd Birch peptides for vaccine
TWI655207B (zh) * 2013-07-30 2019-04-01 再生元醫藥公司 抗活化素a之抗體及其用途
WO2015027154A2 (en) 2013-08-23 2015-02-26 Regeneron Pharmaceuticals, Inc. Diagnostic tests and methods for assessing safety, efficacy or outcome of allergen-specific immunotherapy (sit)
AU2018275657B2 (en) * 2017-06-01 2022-01-06 Regeneron Pharmaceuticals, Inc. Human antibodies to Bet v 1 and methods of use thereof
TWI838389B (zh) 2018-07-19 2024-04-11 美商再生元醫藥公司 雙特異性抗-BCMAx抗-CD3抗體及其用途
EP4175986A1 (en) * 2020-07-01 2023-05-10 Regeneron Pharmaceuticals, Inc. Methods of treating allergy using anti-bet v 1 antibodies

Also Published As

Publication number Publication date
AU2022200272A1 (en) 2022-02-10
JP2022174238A (ja) 2022-11-22
AU2018275657B2 (en) 2022-01-06
PH12019550238A1 (en) 2020-10-19
JP6963036B2 (ja) 2021-11-05
CL2021002851A1 (es) 2022-08-19
MY198270A (en) 2023-08-18
CN110997713B (zh) 2024-01-02
IL298034B1 (en) 2024-01-01
JP2020523004A (ja) 2020-08-06
AU2022200272B2 (en) 2024-10-03
BR112019025150B1 (pt) 2022-11-08
KR102674000B1 (ko) 2024-06-11
ZA201907513B (en) 2022-04-28
CL2021002850A1 (es) 2022-06-24
US20210054056A1 (en) 2021-02-25
AU2018275657A1 (en) 2019-12-19
US11767358B2 (en) 2023-09-26
US20240083986A1 (en) 2024-03-14
KR102329175B1 (ko) 2021-11-19
IL270894A (en) 2020-01-30
KR20210143327A (ko) 2021-11-26
NZ759513A (en) 2022-01-28
EP3630814A1 (en) 2020-04-08
BR112019025150A2 (pt) 2020-06-23
CO2019013196A2 (es) 2020-01-17
JP7162097B2 (ja) 2022-10-27
IL298034B2 (en) 2024-05-01
MX2019014430A (es) 2020-07-14
IL270894B2 (en) 2023-04-01
KR20200012892A (ko) 2020-02-05
JP2021112207A (ja) 2021-08-05
KR102878718B1 (ko) 2025-10-31
IL298034A (en) 2023-01-01
US20180346555A1 (en) 2018-12-06
MX2023000390A (es) 2023-02-13
CL2019003508A1 (es) 2020-06-19
IL270894B (en) 2022-12-01
WO2018222854A1 (en) 2018-12-06
CN110997713A (zh) 2020-04-10
JP7458453B2 (ja) 2024-03-29
KR20240096746A (ko) 2024-06-26
CA3063588A1 (en) 2018-12-06
US10793624B2 (en) 2020-10-06

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Legal Events

Date Code Title Description
S38C Proceedings under section 38 (amendment of specification with leave of commissioner): specification amended