NZ733528A - Polymorphic and amorphous forms of (r)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide - Google Patents

Polymorphic and amorphous forms of (r)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide Download PDF

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Publication number
NZ733528A
NZ733528A NZ733528A NZ73352815A NZ733528A NZ 733528 A NZ733528 A NZ 733528A NZ 733528 A NZ733528 A NZ 733528A NZ 73352815 A NZ73352815 A NZ 73352815A NZ 733528 A NZ733528 A NZ 733528A
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New Zealand
Prior art keywords
pattern
polymorph
angular positions
dioxocyclohexa
dienyl
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NZ733528A
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English (en)
Inventor
Paul Mollard
Christopher R Cornell
Kieron E Wesson
Peter Giannousis
Shazad Suchit
Mahmoud Mirmehrabi
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Ptc Therapeutics Inc
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Priority to NZ771179A priority Critical patent/NZ771179B2/en
Publication of NZ733528A publication Critical patent/NZ733528A/en

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    • A61K31/16—Amides, e.g. hydroxamic acids
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NZ733528A 2014-12-16 2015-12-16 Polymorphic and amorphous forms of (r)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide NZ733528A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NZ771179A NZ771179B2 (en) 2015-12-16 Polymorphic and amorphous forms of (r)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide

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Application Number Priority Date Filing Date Title
US201462092743P 2014-12-16 2014-12-16
US201562133276P 2015-03-13 2015-03-13
PCT/US2015/066211 WO2016100579A1 (en) 2014-12-16 2015-12-16 Polymorphic and amorphous forms of (r)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide

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NZ733528A true NZ733528A (en) 2021-07-30

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US (5) US10251847B2 (enExample)
EP (2) EP3233786B1 (enExample)
JP (4) JP6810692B2 (enExample)
KR (1) KR102626895B1 (enExample)
CN (2) CN114702406B (enExample)
AU (3) AU2015364640B2 (enExample)
BR (1) BR112017012988B1 (enExample)
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DK (1) DK3233786T3 (enExample)
ES (1) ES2912585T3 (enExample)
HU (1) HUE058877T2 (enExample)
IL (1) IL252953A0 (enExample)
MX (2) MX385049B (enExample)
NZ (1) NZ733528A (enExample)
PL (1) PL3233786T3 (enExample)
PT (1) PT3233786T (enExample)
RU (1) RU2770091C2 (enExample)
SG (2) SG10202003299PA (enExample)
SI (1) SI3233786T1 (enExample)
WO (1) WO2016100579A1 (enExample)
ZA (1) ZA201704639B (enExample)

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JP7117241B2 (ja) 2015-12-16 2022-08-12 ピーティーシー セラピューティクス， インコーポレイテッド 混合されたトコール組成物からアルファ－トコトリエノールを富化するための改良された方法
EP3389646A1 (en) 2015-12-17 2018-10-24 BioElectron Technology Corporation Flouroalkyl, flouroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders
JP2018083799A (ja) 2016-11-15 2018-05-31 バイオエレクトロン テクノロジー コーポレイション ２−置換アミノ−ナフト［１，２−ｄ］イミダゾール−５−オン化合物またはその製薬学上許容される塩
HUE066196T2 (hu) 2018-10-17 2024-07-28 Ptc Therapeutics Inc 2,3,5-trimetil-6-nonilciklohexa-2,5-dién-1,4-dion alfa-szinukleinopátiák, tauopátiák és egyéb rendellenességek szuppresszálására és kezelésére
TWI886158B (zh) 2019-10-10 2025-06-11 加拿大商再諾製藥公司 選擇性鉀通道調節劑之固態晶型
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EP4366700A1 (en) 2021-07-08 2024-05-15 PTC Therapeutics, Inc. Pharmaceutical compositions comprising 2,3,5-trimethyl-6-nonylcyclohexa-2,5-diene-1,4-dione
JPWO2024058099A1 (enExample) 2022-09-12 2024-03-21
IL319633A (en) * 2022-09-30 2025-05-01 Ptc Therapeutics Inc Oxygen cleavage method of trolox amide
WO2025193975A1 (en) 2024-03-13 2025-09-18 Ptc Therapeutics, Inc. Formulations for stabilizing dissolution of medicaments

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