SG10202003299PA - Polymorphic and amorphous forms of (r)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide - Google Patents
Polymorphic and amorphous forms of (r)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamideInfo
- Publication number
- SG10202003299PA SG10202003299PA SG10202003299PA SG10202003299PA SG10202003299PA SG 10202003299P A SG10202003299P A SG 10202003299PA SG 10202003299P A SG10202003299P A SG 10202003299PA SG 10202003299P A SG10202003299P A SG 10202003299PA SG 10202003299P A SG10202003299P A SG 10202003299PA
- Authority
- SG
- Singapore
- Prior art keywords
- dioxocyclohexa
- butanamide
- dienyl
- polymorphic
- trimethyl
- Prior art date
Links
- BAANPNDZFYBQIB-CQSZACIVSA-N (2r)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)butanamide Chemical compound CC1=C(C)C(=O)C(CC[C@@](C)(O)C(N)=O)=C(C)C1=O BAANPNDZFYBQIB-CQSZACIVSA-N 0.000 title 1
Classifications
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- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
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- A61K31/00—Medicinal preparations containing organic active ingredients
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- A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
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- C07C235/76—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US201462092743P | 2014-12-16 | 2014-12-16 | |
US201562133276P | 2015-03-13 | 2015-03-13 |
Publications (1)
Publication Number | Publication Date |
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SG10202003299PA true SG10202003299PA (en) | 2020-05-28 |
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Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
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SG11201704968XA SG11201704968XA (en) | 2014-12-16 | 2015-12-16 | Polymorphic and amorphous forms of (r)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide |
SG10202003299PA SG10202003299PA (en) | 2014-12-16 | 2015-12-16 | Polymorphic and amorphous forms of (r)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
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SG11201704968XA SG11201704968XA (en) | 2014-12-16 | 2015-12-16 | Polymorphic and amorphous forms of (r)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide |
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US (5) | US10251847B2 (en) |
EP (2) | EP4059922A1 (en) |
JP (4) | JP6810692B2 (en) |
KR (1) | KR102626895B1 (en) |
CN (2) | CN114702406A (en) |
AU (3) | AU2015364640B2 (en) |
BR (1) | BR112017012988B1 (en) |
CA (1) | CA2971252A1 (en) |
DK (1) | DK3233786T3 (en) |
ES (1) | ES2912585T3 (en) |
HU (1) | HUE058877T2 (en) |
IL (1) | IL252953A0 (en) |
MX (2) | MX2017008063A (en) |
NZ (1) | NZ733528A (en) |
PL (1) | PL3233786T3 (en) |
PT (1) | PT3233786T (en) |
RU (1) | RU2770091C2 (en) |
SG (2) | SG11201704968XA (en) |
SI (1) | SI3233786T1 (en) |
WO (1) | WO2016100579A1 (en) |
ZA (1) | ZA201704639B (en) |
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MX359292B (en) | 2005-06-01 | 2018-09-24 | Bioelectron Tech Corp | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomakers. |
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ES2553557T3 (en) | 2008-10-28 | 2015-12-10 | Edison Pharmaceuticals, Inc. | Process for the production of alpha-tocotrienol and derivatives |
WO2013013078A1 (en) | 2011-07-19 | 2013-01-24 | Edison Pharmeceuticals, Inc. | Methods for selective oxidation of alpha tocotrienol in the presence of non-alpha tocotrienols |
HUE058877T2 (en) | 2014-12-16 | 2022-09-28 | Ptc Therapeutics Inc | Polymorphic and amorphous forms of (r)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide |
JP7117241B2 (en) | 2015-12-16 | 2022-08-12 | ピーティーシー セラピューティクス, インコーポレイテッド | Improved methods for enriching alpha-tocotrienols from mixed tocol compositions |
EP3389646A1 (en) | 2015-12-17 | 2018-10-24 | BioElectron Technology Corporation | Flouroalkyl, flouroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders |
JP2018083799A (en) | 2016-11-15 | 2018-05-31 | バイオエレクトロン テクノロジー コーポレイション | 2-SUBSTITUTED AMINO-NAPHTHO[1,2-d]IMIDAZOLE-5-ONE COMPOUND OR PHARMACEUTICALLY ALLOWABLE SALTS THEREOF |
MX2021004329A (en) | 2018-10-17 | 2021-06-08 | Ptc Therapeutics Inc | 2,3,5-trimethyl-6-nonylcyclohexa-2,5-diene-1,4-dione for suppressing and treating î±-synucleinopathies, tauopathies, and other disorders. |
WO2023283466A1 (en) | 2021-07-08 | 2023-01-12 | Ptc Therapeutics, Inc. | Pharmaceutical compositions comprising 2,3,5-trimethyl-6-nonylcyclohexa-2,5-diene-1,4-dione |
WO2024058099A1 (en) * | 2022-09-12 | 2024-03-21 | 住友ファーマ株式会社 | Granules for suspension |
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