NZ701099A - Ketol-acid reductoisomerase enzymes and methods of use - Google Patents
Ketol-acid reductoisomerase enzymes and methods of useInfo
- Publication number
- NZ701099A NZ701099A NZ701099A NZ70109913A NZ701099A NZ 701099 A NZ701099 A NZ 701099A NZ 701099 A NZ701099 A NZ 701099A NZ 70109913 A NZ70109913 A NZ 70109913A NZ 701099 A NZ701099 A NZ 701099A
- Authority
- NZ
- New Zealand
- Prior art keywords
- ketol
- methods
- acid reductoisomerase
- polypeptides
- reductoisomerase enzymes
- Prior art date
Links
- 108010000200 Ketol-acid reductoisomerase Proteins 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 230000006696 biosynthetic metabolic pathway Effects 0.000 abstract 2
- ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/16—Butanols
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01086—Ketol-acid reductoisomerase (1.1.1.86)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
- C12R2001/85—Saccharomyces
- C12R2001/865—Saccharomyces cerevisiae
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261645832P | 2012-05-11 | 2012-05-11 | |
| US201361787480P | 2013-03-15 | 2013-03-15 | |
| PCT/US2013/040627 WO2013176909A2 (en) | 2012-05-11 | 2013-05-10 | Ketol-acid reductoisomerase enzymes and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ701099A true NZ701099A (en) | 2017-04-28 |
Family
ID=48877508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ701099A NZ701099A (en) | 2012-05-11 | 2013-05-10 | Ketol-acid reductoisomerase enzymes and methods of use |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9169467B2 (https=) |
| EP (1) | EP2847326A2 (https=) |
| JP (1) | JP6321631B2 (https=) |
| KR (1) | KR20150014953A (https=) |
| CN (1) | CN104619835B (https=) |
| AU (1) | AU2013266727A1 (https=) |
| BR (1) | BR112014028153A2 (https=) |
| CA (1) | CA2873109A1 (https=) |
| MX (2) | MX370134B (https=) |
| NZ (1) | NZ701099A (https=) |
| WO (1) | WO2013176909A2 (https=) |
| ZA (1) | ZA201407713B (https=) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
| EP2134849B1 (en) | 2007-04-18 | 2013-07-10 | Butamax (TM) Advanced Biofuels LLC | Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes |
| US8188250B2 (en) | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
| US9206447B2 (en) | 2008-09-29 | 2015-12-08 | Butamax Advanced Biofuels Llc | Recombinant yeast host cells comprising FE-S cluster proteins |
| NZ600509A (en) | 2009-12-29 | 2014-08-29 | Butamax Tm Advanced Biofuels | Alcohol dehydrogenases (adh) useful for fermentive production of lower alkyl alcohols |
| PH12012501658A1 (en) | 2010-02-17 | 2023-04-28 | Butamax Tm Advanced Biofuels | Improving activity of fe-s cluster requiring proteins |
| WO2012033832A2 (en) | 2010-09-07 | 2012-03-15 | Butamax(Tm) Advanced Biofuels Llc | Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion |
| MX347976B (es) | 2011-03-24 | 2017-05-22 | Butamax(Tm) Advanced Biofuels Llc | Celulas huesped y metodos para producir isobutanol. |
| WO2013016717A2 (en) | 2011-07-28 | 2013-01-31 | Butamax(Tm) Advanced Biofuels Llc | Keto-isovalerate decarboxylase enzymes and methods of use thereof |
| CA2861613A1 (en) | 2011-12-30 | 2013-07-04 | Butamax Advanced Biofuels Llc | Fermentative production of alcohols |
| US9689004B2 (en) | 2012-03-23 | 2017-06-27 | Butamax Advanced Biofuels Llc | Acetate supplemention of medium for butanologens |
| NZ701099A (en) | 2012-05-11 | 2017-04-28 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase enzymes and methods of use |
| BR112015003701A2 (pt) | 2012-08-22 | 2017-12-12 | Butamax Advanced Biofuels Llc | células hospedeiras recombinantes, método para aprimoramento, processo para a produção de um álcool, polinucleotídeo isolado, cassete de expressão e composição |
| US9840724B2 (en) | 2012-09-21 | 2017-12-12 | Butamax Advanced Biofuels Llc | Production of renewable hydrocarbon compositions |
| WO2014052670A1 (en) | 2012-09-26 | 2014-04-03 | Butamax (Tm) Advanced Biofuels Llc | Polypeptides with ketol-acid reductoisomerase activity |
| US9273330B2 (en) | 2012-10-03 | 2016-03-01 | Butamax Advanced Biofuels Llc | Butanol tolerance in microorganisms |
| US9650624B2 (en) | 2012-12-28 | 2017-05-16 | Butamax Advanced Biofuels Llc | DHAD variants for butanol production |
| US9441250B2 (en) | 2013-03-14 | 2016-09-13 | Butamax Advanced Biofuels Llc | Glycerol 3- phosphate dehydrogenase for butanol production |
| US9580705B2 (en) | 2013-03-15 | 2017-02-28 | Butamax Advanced Biofuels Llc | DHAD variants and methods of screening |
| WO2014144210A2 (en) | 2013-03-15 | 2014-09-18 | Butamax Advanced Biofuels Llc | Competitive growth and/or production advantage for butanologen microorganism |
| EP3180440A4 (en) | 2014-08-11 | 2018-01-10 | Butamax Advanced Biofuels LLC | Yeast preparations and methods of making the same |
| WO2018089333A1 (en) | 2016-11-09 | 2018-05-17 | Danisco Us Inc. | Yeast with improved alcohol production |
| CN108728477B (zh) * | 2017-04-24 | 2022-02-22 | 华东理工大学 | 一种高效的转座突变系统及构建方法 |
| KR101960501B1 (ko) * | 2017-09-15 | 2019-03-21 | 고려대학교 산학협력단 | Ｎａｄｈ 친화적인 신규 케톨산 리덕토아이소머라제 |
| US11308274B2 (en) | 2019-05-17 | 2022-04-19 | International Business Machines Corporation | Word grouping using a plurality of models |
| CN113278568B (zh) * | 2020-05-27 | 2022-10-21 | 安徽华恒生物科技股份有限公司 | 生产l-缬氨酸的重组大肠杆菌及其应用 |
| KR102801647B1 (ko) * | 2022-08-12 | 2025-04-30 | 씨제이제일제당 주식회사 | 케톨산 리덕토아이소머라제 변이체 및 이를 이용한 l-발린 생산 방법 |
| EP4674950A4 (en) * | 2023-03-30 | 2026-05-06 | Anhui Huaheng Biotechnology Co Ltd | Recombinant microorganism for producing pantoic acid and use thereof |
| CN117417949B (zh) * | 2023-10-19 | 2024-12-20 | 云南农业大学 | 雪胆细胞色素氧化酶HcCYP81Q58转基因酵母工程菌及其应用 |
Family Cites Families (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4865973A (en) | 1985-09-13 | 1989-09-12 | Queen's University At Kingston | Process for extractive fermentation |
| FR2696190B1 (fr) | 1992-09-25 | 1994-12-09 | Agronomique Inst Nat Rech | Acide nucléique codant pour une alpha-acétolactate synthase et ses applications. |
| BRPI0013315B8 (pt) | 1999-08-18 | 2018-02-27 | Du Pont | fragmento de ácido nucleico isolado, polipeptídeo, gene quimérico, microorganismo, microorganismo recombinante , e. coli recombinante, linhagem klp23 de e. coli recombinante, linhagem rj8 de e. coli recombinante, vetor pdt29, vetor pkp32 e processos de bioprodução de 1,3-propanodiol |
| CA2404260A1 (en) | 2000-03-21 | 2001-09-27 | Elitra Pharmaceuticals, Inc. | Identification of essential genes in prokaryotes |
| US6586229B1 (en) | 2000-06-01 | 2003-07-01 | North Carolina State University | Method for the production of ρ-Hydroxybenzoate in species of pseudomonas and agrobacterium |
| RU2004102689A (ru) | 2001-07-02 | 2005-05-10 | Канека Корпорейшн (Jp) | Способ модифицирования фермента и вариант оксидоредуктазы |
| CN102210376B (zh) | 2003-03-10 | 2014-12-31 | 波伊特研究股份有限公司 | 利用生淀粉生产乙醇的方法 |
| SE526429C2 (sv) | 2003-10-24 | 2005-09-13 | Swedish Biofuels Ab | Metod för att framställa syreinnehållande föreningar utgående från biomassa |
| CA2603774C (en) | 2005-04-12 | 2015-11-17 | E.I. Du Pont De Nemours And Company | System and process for biomass treatment |
| US9297028B2 (en) | 2005-09-29 | 2016-03-29 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
| MX359740B (es) * | 2005-10-26 | 2018-10-09 | Du Pont | Produccion fermentativa de alcoholes de cuatro atomos de carbono. |
| US8273558B2 (en) * | 2005-10-26 | 2012-09-25 | Butamax(Tm) Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US9303225B2 (en) | 2005-10-26 | 2016-04-05 | Butamax Advanced Biofuels Llc | Method for the production of isobutanol by recombinant yeast |
| US8206970B2 (en) | 2006-05-02 | 2012-06-26 | Butamax(Tm) Advanced Biofuels Llc | Production of 2-butanol and 2-butanone employing aminobutanol phosphate phospholyase |
| US8828704B2 (en) | 2006-05-02 | 2014-09-09 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US7659104B2 (en) | 2006-05-05 | 2010-02-09 | E.I. Du Pont De Nemours And Company | Solvent tolerant microorganisms and methods of isolation |
| US7541173B2 (en) | 2006-06-15 | 2009-06-02 | E.I. Du Pont De Nemours And Company | Solvent tolerant microorganisms and methods of isolation |
| US8017364B2 (en) | 2006-12-12 | 2011-09-13 | Butamax(Tm) Advanced Biofuels Llc | Solvent tolerant microorganisms |
| PL389665A1 (pl) | 2007-02-09 | 2010-07-05 | The Regents of the University of CaliforniaThe Regents of the University of California | Wytwarzanie biopaliwa przez rekombinowane mikroorganizmy |
| EP2134849B1 (en) | 2007-04-18 | 2013-07-10 | Butamax (TM) Advanced Biofuels LLC | Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes |
| EP2060632A1 (en) | 2007-10-29 | 2009-05-20 | Technische Universität Berlin | Method of modifying a yeast cell for the production of ethanol |
| EP2215243A2 (en) | 2007-10-31 | 2010-08-11 | GEVO, Inc. | Methods for the economical production of biofuel precursor that is also a biofuel from biomass |
| WO2009078108A1 (en) | 2007-12-17 | 2009-06-25 | Suntory Holdings Limited | Mutant ilv5 gene and use thereof |
| ES2553726T3 (es) | 2007-12-20 | 2015-12-11 | Butamax (Tm) Advanced Biofuels Llc | Cetol-ácido reductoisomerasa que utiliza NADH |
| US8518678B2 (en) | 2007-12-21 | 2013-08-27 | Butamax(Tm) Advanced Biofuels Llc | Strain comprising increased expression of a CFA coding region for butanol production |
| US8372612B2 (en) | 2007-12-21 | 2013-02-12 | Butamax(Tm) Advanced Biofuels Llc | Production of four carbon alcohols using improved strain |
| WO2009086423A2 (en) | 2007-12-23 | 2009-07-09 | Gevo, Inc. | Yeast organism producing isobutanol at a high yield |
| US8188250B2 (en) | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
| US8389252B2 (en) | 2008-05-12 | 2013-03-05 | Butamax(Tm) Advanced Biofuels Llc | Yeast strain for production of four carbon alcohols |
| WO2009143455A2 (en) | 2008-05-22 | 2009-11-26 | Microbia, Inc. | Engineering resistance to aliphatic alcohols |
| BRPI0909989A2 (pt) | 2008-06-05 | 2021-06-22 | Butamax Advanced Biofuels Llc | célula de levedura recombinante e método para a produção de um produto |
| AU2009296227A1 (en) | 2008-09-29 | 2010-04-01 | Butamax(Tm) Advanced Biofuels Llc | Enhanced pyruvate to 2,3-butanediol conversion in lactic acid bacteria |
| CA2736420A1 (en) | 2008-09-29 | 2010-04-01 | Butamaxtm Advanced Biofuels Llc | Enhanced dihydroxy-acid dehydratase activity in lactic acid bacteria |
| MX2011003238A (es) | 2008-09-29 | 2011-04-28 | Butamax Tm Advanced Biofuels | Identificacion y uso de dihidroxiacido deshidratasas [2fe-2s] bacterianas. |
| US9206447B2 (en) | 2008-09-29 | 2015-12-08 | Butamax Advanced Biofuels Llc | Recombinant yeast host cells comprising FE-S cluster proteins |
| WO2010037119A1 (en) | 2008-09-29 | 2010-04-01 | Butamax™ Advanced Biofuels LLC | Enhanced iron-sulfur cluster formation for increased dihydroxy-acid dehydratase activity in lactic acid bacteria |
| CA2737112A1 (en) | 2008-10-27 | 2010-06-03 | Butamax Advanced Biofuels Llc | Carbon pathway optimized production hosts for the production of isobutanol |
| CA2779262C (en) | 2008-10-31 | 2021-09-07 | Gevo, Inc. | Engineered microorganisms capable of converting pyruvate to isobutanol under anaerobic conditions |
| US8828694B2 (en) | 2008-11-13 | 2014-09-09 | Butamax Advanced Biofuels Llc | Production of isobutanol in yeast mitochondria |
| US8465964B2 (en) | 2008-11-13 | 2013-06-18 | Butamax (TM) Advanced Biofules LLC | Increased production of isobutanol in yeast with reduced mitochondrial amino acid biosynthesis |
| US8652823B2 (en) | 2008-12-03 | 2014-02-18 | Butamax(Tm) Advanced Biofuels Llc | Strain for butanol production with increased membrane unsaturated trans fatty acids |
| US8795992B2 (en) | 2008-12-29 | 2014-08-05 | Butamax Advanced Biofuels Llc | Yeast with increased butanol tolerance involving cell wall integrity pathway |
| US8557562B2 (en) | 2008-12-29 | 2013-10-15 | Butamax(Tm) Advanced Biofuels Llc | Yeast with increased butanol tolerance involving filamentous growth response |
| US8455225B2 (en) | 2008-12-29 | 2013-06-04 | Butamax Advanced Biofuels Llc | Yeast with increased butanol tolerance involving high osmolarity/glycerol response pathway |
| US8614085B2 (en) | 2009-02-27 | 2013-12-24 | Butamax(Tm) Advanced Biofuels Llc | Yeast with increased butanol tolerance involving a multidrug efflux pump gene |
| US20120058541A1 (en) | 2009-05-22 | 2012-03-08 | Butamax(Tm) Advanced Biofuels Llc | Engineering resistance to aliphatic alcohols |
| BR112012003241A2 (pt) | 2009-08-12 | 2015-09-01 | Gevo Inc | Localização de via de isobutanol citosólico para a produção de isobutanol |
| EP2483401B1 (en) | 2009-09-29 | 2017-06-21 | Butamax (TM) Advanced Biofuels LLC | Improved yeast production host cells |
| AU2010300642B2 (en) | 2009-09-29 | 2015-05-14 | Butamax(Tm) Advanced Biofuels Llc | Fermentive production of isobutanol using highly effective ketol-acid reductoisomerase enzymes |
| AU2010300722A1 (en) | 2009-09-29 | 2012-04-12 | Butamax(Tm) Advanced Biofuels Llc | Improved flux to acetolactate-derived products in lactic acid bacteria |
| US20110195505A1 (en) | 2009-10-08 | 2011-08-11 | Butamax(Tm) Advanced Biofuels Llc | Bacterial strains for butanol production |
| WO2011066356A1 (en) | 2009-11-24 | 2011-06-03 | Gevo, Inc. | Methods of increasing dihydroxy acid dehydratase activity to improve production of fuels, chemicals, and amino acids |
| NZ600509A (en) | 2009-12-29 | 2014-08-29 | Butamax Tm Advanced Biofuels | Alcohol dehydrogenases (adh) useful for fermentive production of lower alkyl alcohols |
| NZ600585A (en) | 2009-12-29 | 2014-07-25 | Butamax Tm Advanced Biofuels | Expression of hexose kinase in recombinant host cells |
| MX2012009362A (es) | 2010-02-12 | 2013-05-28 | Gevo Inc | Microorganismos de levadura con acumulación reducida de subproductos para una producción mejorada de combustibles, químicos y aminoácidos. |
| PH12012501658A1 (en) | 2010-02-17 | 2023-04-28 | Butamax Tm Advanced Biofuels | Improving activity of fe-s cluster requiring proteins |
| CA2801576A1 (en) | 2010-06-17 | 2011-12-22 | Butamax(Tm) Advanced Biofuels Llc | Yeast production culture for the production of butanol |
| US8871488B2 (en) | 2010-06-18 | 2014-10-28 | Butamax Advanced Biofuels Llc | Recombinant host cells comprising phosphoketolases |
| WO2012033832A2 (en) * | 2010-09-07 | 2012-03-15 | Butamax(Tm) Advanced Biofuels Llc | Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion |
| MX347976B (es) | 2011-03-24 | 2017-05-22 | Butamax(Tm) Advanced Biofuels Llc | Celulas huesped y metodos para producir isobutanol. |
| US20120258873A1 (en) | 2011-04-06 | 2012-10-11 | Butamax(Tm) Advanced Biofuels Llc | Reduction of 2,3-dihydroxy-2-methyl butyrate (dhmb) in butanol production |
| CA2838519A1 (en) | 2011-06-17 | 2012-12-20 | Butamax Advanced Biofuels Llc | Lignocellulosic hydrolysates as feedstocks for isobutanol fermentation |
| WO2013016717A2 (en) | 2011-07-28 | 2013-01-31 | Butamax(Tm) Advanced Biofuels Llc | Keto-isovalerate decarboxylase enzymes and methods of use thereof |
| CA2861613A1 (en) | 2011-12-30 | 2013-07-04 | Butamax Advanced Biofuels Llc | Fermentative production of alcohols |
| CA2862450A1 (en) | 2011-12-30 | 2013-07-04 | Butamax Advanced Biofuels Llc | Genetic switches for butanol production |
| US9689004B2 (en) | 2012-03-23 | 2017-06-27 | Butamax Advanced Biofuels Llc | Acetate supplemention of medium for butanologens |
| NZ701099A (en) | 2012-05-11 | 2017-04-28 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase enzymes and methods of use |
| WO2014052670A1 (en) | 2012-09-26 | 2014-04-03 | Butamax (Tm) Advanced Biofuels Llc | Polypeptides with ketol-acid reductoisomerase activity |
| US9273330B2 (en) | 2012-10-03 | 2016-03-01 | Butamax Advanced Biofuels Llc | Butanol tolerance in microorganisms |
| US9650624B2 (en) | 2012-12-28 | 2017-05-16 | Butamax Advanced Biofuels Llc | DHAD variants for butanol production |
| US20140186911A1 (en) | 2012-12-28 | 2014-07-03 | Butamax Advanced Biofuels Llc | Recombinant host cells and methods for producing butanol |
| US9441250B2 (en) | 2013-03-14 | 2016-09-13 | Butamax Advanced Biofuels Llc | Glycerol 3- phosphate dehydrogenase for butanol production |
| US9580705B2 (en) | 2013-03-15 | 2017-02-28 | Butamax Advanced Biofuels Llc | DHAD variants and methods of screening |
-
2013
- 2013-05-10 NZ NZ701099A patent/NZ701099A/en not_active IP Right Cessation
- 2013-05-10 MX MX2018004620A patent/MX370134B/es unknown
- 2013-05-10 EP EP13742293.7A patent/EP2847326A2/en not_active Withdrawn
- 2013-05-10 US US13/891,963 patent/US9169467B2/en active Active
- 2013-05-10 CN CN201380036539.6A patent/CN104619835B/zh not_active Expired - Fee Related
- 2013-05-10 MX MX2014013446A patent/MX2014013446A/es unknown
- 2013-05-10 AU AU2013266727A patent/AU2013266727A1/en not_active Abandoned
- 2013-05-10 WO PCT/US2013/040627 patent/WO2013176909A2/en not_active Ceased
- 2013-05-10 JP JP2015511775A patent/JP6321631B2/ja active Active
- 2013-05-10 KR KR1020147034485A patent/KR20150014953A/ko not_active Withdrawn
- 2013-05-10 CA CA2873109A patent/CA2873109A1/en not_active Abandoned
- 2013-05-10 BR BR112014028153-0A patent/BR112014028153A2/pt not_active Application Discontinuation
-
2014
- 2014-10-23 ZA ZA2014/07713A patent/ZA201407713B/en unknown
-
2015
- 2015-09-14 US US14/853,108 patent/US9388392B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| BR112014028153A2 (pt) | 2018-05-08 |
| JP6321631B2 (ja) | 2018-05-09 |
| KR20150014953A (ko) | 2015-02-09 |
| EP2847326A2 (en) | 2015-03-18 |
| US9388392B2 (en) | 2016-07-12 |
| US20160032255A1 (en) | 2016-02-04 |
| US9169467B2 (en) | 2015-10-27 |
| MX2014013446A (es) | 2014-12-08 |
| WO2013176909A2 (en) | 2013-11-28 |
| AU2013266727A1 (en) | 2014-11-06 |
| WO2013176909A3 (en) | 2014-02-13 |
| JP2015517310A (ja) | 2015-06-22 |
| CN104619835B (zh) | 2018-06-19 |
| CA2873109A1 (en) | 2013-11-28 |
| CN104619835A (zh) | 2015-05-13 |
| ZA201407713B (en) | 2016-05-25 |
| US20140051133A1 (en) | 2014-02-20 |
| MX370134B (es) | 2019-12-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NZ701099A (en) | Ketol-acid reductoisomerase enzymes and methods of use | |
| WO2012129084A3 (en) | Glucosylceramide synthase inhibitors | |
| TN2015000091A1 (en) | Glucosylceramide synthase inhibitors | |
| WO2012104007A3 (de) | 7-azaindolderivate | |
| CL2013000238A1 (es) | Uso de inhibores de la succinato deshidrogenasa y/o inhibidores del complejo iii para mejorar la relacion entre microorganismos dañinos y beneficiosos. | |
| EP2818543B8 (en) | Bacillus, hyaluronic acid enzyme, and uses thereof | |
| IN2014CN02100A (https=) | ||
| BR112014024675A8 (pt) | célula hospedeira recombinante, cultura celular | |
| EP2723263A4 (en) | SYSTEMS, DEVICES, AND METHODS FOR INDUCING PROGRAMMED CELL DEATH OF ADIPOSE TISSUES | |
| NZ606589A (en) | 5-chloro-4-hydroxy-1-methyl-2-oxo-n-phenyl-1,2-dihydroquinoline-3-carboxamide, salts and uses thereof | |
| EP2605326A4 (en) | Fluidized-bed electrode system, and high-capacity power storage and water treatment method using same | |
| MX375786B (es) | Biosintesis microbiana de ergotioneina. | |
| EP4582090A3 (en) | Composition comprising pegylated arginine deiminase | |
| SG10201804952QA (en) | Glucosylceramide synthase inhibitors | |
| EP2880050A4 (en) | NOVEL ENZYMES, ENZYME COMPONENTS AND USES THEREOF | |
| ZA201208522B (en) | Methods for measuring enzyme activity useful in determining cell viability in non-purified sapmles | |
| MX365464B (es) | Prodecimiento para preparar inhibidores de la glucosilceramida sintasa. | |
| PH12014500234A1 (en) | Endogenous dnase activity to reduce dna content | |
| EP2909303A4 (en) | Bioreactor system and methods for alternative cell culture between static and dynamic | |
| EP3049529A4 (en) | Engineered enzyme having acetoacetyl-coa hydrolase activity, microorganisms comprising same, and methods of using same | |
| EP3075846A4 (en) | Cell culture medium and culture method using same | |
| EP2841408A4 (en) | METHODS OF MAINTAINING AND IMPROVING CELL BIOLOGICAL FUNCTION AND ACTIVITY | |
| TN2013000368A1 (en) | Glucosylceramide synthase inhibitors | |
| SG10201602155XA (en) | Cleavable cellulosic sponge development for 3 dimensional cell culture and spheroids retrieval | |
| AU337117S (en) | Insole |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 10 MAY 2019 BY CPA GLOBAL Effective date: 20180329 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 10 MAY 2020 BY CPA GLOBAL Effective date: 20190404 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 10 MAY 2021 BY CPA GLOBAL Effective date: 20200403 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 10 MAY 2022 BY CPA GLOBAL Effective date: 20210401 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 10 MAY 2023 BY HOULIHAN2 PTY LTD Effective date: 20220427 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 10 MAY 2024 BY COMPUTER PACKAGES INC Effective date: 20230417 |
|
| LAPS | Patent lapsed |