NZ597252A - Compounds for inhibiting mitotic progression - Google Patents

Compounds for inhibiting mitotic progression

Info

Publication number
NZ597252A
NZ597252A NZ597252A NZ59725207A NZ597252A NZ 597252 A NZ597252 A NZ 597252A NZ 597252 A NZ597252 A NZ 597252A NZ 59725207 A NZ59725207 A NZ 59725207A NZ 597252 A NZ597252 A NZ 597252A
Authority
NZ
New Zealand
Prior art keywords
cancer
lymphoma
kinase inhibitor
aurora kinase
leukemia
Prior art date
Application number
NZ597252A
Other languages
English (en)
Inventor
Christopher F Claiborne
Original Assignee
Millennium Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39315133&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ597252(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Millennium Pharm Inc filed Critical Millennium Pharm Inc
Priority to NZ611898A priority Critical patent/NZ611898A/en
Publication of NZ597252A publication Critical patent/NZ597252A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NZ597252A 2006-11-16 2007-11-14 Compounds for inhibiting mitotic progression NZ597252A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NZ611898A NZ611898A (en) 2006-11-16 2007-11-14 Compounds for inhibiting mitotic progression

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85934006P 2006-11-16 2006-11-16
NZ577042A NZ577042A (en) 2006-11-16 2007-11-14 Compounds for inhibiting mitotic progression

Publications (1)

Publication Number Publication Date
NZ597252A true NZ597252A (en) 2013-06-28

Family

ID=39315133

Family Applications (3)

Application Number Title Priority Date Filing Date
NZ597252A NZ597252A (en) 2006-11-16 2007-11-14 Compounds for inhibiting mitotic progression
NZ611898A NZ611898A (en) 2006-11-16 2007-11-14 Compounds for inhibiting mitotic progression
NZ577042A NZ577042A (en) 2006-11-16 2007-11-14 Compounds for inhibiting mitotic progression

Family Applications After (2)

Application Number Title Priority Date Filing Date
NZ611898A NZ611898A (en) 2006-11-16 2007-11-14 Compounds for inhibiting mitotic progression
NZ577042A NZ577042A (en) 2006-11-16 2007-11-14 Compounds for inhibiting mitotic progression

Country Status (34)

Country Link
US (7) US8026246B2 (OSRAM)
EP (4) EP2497772B1 (OSRAM)
JP (3) JP5102839B2 (OSRAM)
KR (2) KR101110458B1 (OSRAM)
CN (2) CN101547924B (OSRAM)
AR (1) AR064246A1 (OSRAM)
AT (1) ATE556076T1 (OSRAM)
AU (1) AU2007322046B2 (OSRAM)
BR (1) BRPI0718803B8 (OSRAM)
CA (1) CA2669680C (OSRAM)
CL (1) CL2007003244A1 (OSRAM)
CR (3) CR10782A (OSRAM)
CY (1) CY1112828T1 (OSRAM)
DK (2) DK2086981T3 (OSRAM)
EA (1) EA015779B1 (OSRAM)
ES (3) ES2537451T3 (OSRAM)
GE (1) GEP20125459B (OSRAM)
HR (2) HRP20120490T1 (OSRAM)
IL (1) IL198690A0 (OSRAM)
MA (1) MA30988B1 (OSRAM)
MX (3) MX348568B (OSRAM)
MY (1) MY153243A (OSRAM)
NO (1) NO343338B1 (OSRAM)
NZ (3) NZ597252A (OSRAM)
PH (1) PH12012502057B1 (OSRAM)
PL (2) PL2497772T3 (OSRAM)
PT (2) PT2086981E (OSRAM)
RS (2) RS53788B1 (OSRAM)
SG (2) SG10201503350TA (OSRAM)
SI (2) SI2497772T1 (OSRAM)
TW (1) TWI401255B (OSRAM)
UA (1) UA94129C2 (OSRAM)
WO (1) WO2008063525A1 (OSRAM)
ZA (1) ZA200903279B (OSRAM)

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WO2010074724A1 (en) * 2008-12-22 2010-07-01 Millennium Pharmaceuticals, Inc. Combination of aurora kinase inhibitors and anti-cd20 antibodies
JO3635B1 (ar) 2009-05-18 2020-08-27 Millennium Pharm Inc مركبات صيدلانية صلبة وطرق لانتاجها
JO3434B1 (ar) * 2009-07-31 2019-10-20 Millennium Pharm Inc مركبات صيدلانية لمعالجة السرطان وامراض واضطرابات اخري
US8653064B2 (en) 2010-02-19 2014-02-18 Millennium Pharmaceuticals, Inc. Crystalline forms of sodium 4-{[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-D][2]benzazepin-2-yl]amino}-2-methoxybenzoate
US20120107304A1 (en) 2010-04-27 2012-05-03 Boehringer Ingelheim International Gmbh Combination therapy in treatment of oncological and fibrotic diseases
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UY34114A (es) 2011-06-03 2013-01-03 Millennium Pharm Inc Combinación de inhibidores de mek e inhibidores selectivos de la quiinasa aurora a
US20130303519A1 (en) 2012-03-20 2013-11-14 Millennium Pharmaceuticals, Inc. Methods of treating cancer using aurora kinase inhibitors
CN103772391A (zh) * 2012-10-23 2014-05-07 杨子娇 一类治疗房角狭窄的化合物及其用途
US9724354B2 (en) 2013-03-22 2017-08-08 Millennium Pharmaceuticals, Inc. Combination of catalytic mTORC1/2 inhibitors and selective inhibitors of Aurora A kinase
EP3076963A4 (en) 2013-12-06 2017-09-13 Millennium Pharmaceuticals, Inc. Combination of aurora kinase inhibitors and anti-cd30 antibodies
WO2016106357A1 (en) * 2014-12-23 2016-06-30 Millennnium Pharmaceuticals, Inc. Combination of raf inhibitors and aurora kinase inhibitors
JP2018524292A (ja) 2015-07-21 2018-08-30 ミレニアム ファーマシューティカルズ， インコーポレイテッドＭｉｌｌｅｎｎｉｕｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． オーロラキナーゼインヒビターと化学療法剤の投与
CA2997769A1 (en) 2015-09-09 2017-03-16 Icahn School Of Medicine At Mount Sinai Heterocyclic constrained tricyclic sulfonamides as anti-cancer agents
CN108349961B (zh) 2015-09-09 2022-02-18 西奈山伊坎医学院 杂环受限三环磺酰胺作为抗癌试剂
JP6591036B2 (ja) 2016-02-26 2019-10-16 公益財団法人がん研究会 Ｈｐ１の機能に着目した抗癌剤のスクリーニング方法及び評価系
SG11201807965YA (en) 2016-03-15 2018-10-30 Oryzon Genomics Sa Combinations of lsd1 inhibitors for use in the treatment of solid tumors
JP6188986B1 (ja) * 2017-03-23 2017-08-30 株式会社ノエビア 時計遺伝子発現量調整剤及びエラスチン産生促進剤
WO2019195658A1 (en) 2018-04-05 2019-10-10 Dana-Farber Cancer Institute, Inc. Sting levels as a biomarker for cancer immunotherapy
WO2020049208A1 (es) 2018-09-09 2020-03-12 Fundacio Privada Institut De Recerca De La Sida - Caixa Aurora cinasa como diana para tratar, prevenir o curar una infección por vih o sida
WO2021041532A1 (en) 2019-08-26 2021-03-04 Dana-Farber Cancer Institute, Inc. Use of heparin to promote type 1 interferon signaling
EP4504710A1 (en) 2022-04-07 2025-02-12 Eli Lilly and Company Process for making a kras g12c inhibitor
WO2023196887A1 (en) 2022-04-08 2023-10-12 Eli Lilly And Company Method of treatment including kras g12c inhibitors and aurora a inhibitors
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WO2025075211A1 (en) 2023-10-03 2025-04-10 Takeda Pharmaceutical Company Limited Alisertib and paclitaxel for treating small cell lung cancer
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Also Published As

Publication number Publication date
EA015779B1 (ru) 2011-12-30
CL2007003244A1 (es) 2008-04-04
EP2086981A1 (en) 2009-08-12
EP2497772B1 (en) 2014-10-29
CR10782A (es) 2009-06-24
HK1217699A1 (en) 2017-01-20
EP2497773A1 (en) 2012-09-12
JP5452811B2 (ja) 2014-03-26
CR20140154A (es) 2014-07-23
CN101547924B (zh) 2013-09-25
US11958855B2 (en) 2024-04-16
US20110312942A1 (en) 2011-12-22
HRP20150047T1 (en) 2015-03-13
US8026246B2 (en) 2011-09-27
HK1175778A1 (en) 2013-07-12
MX2009004670A (es) 2009-05-15
PT2086981E (pt) 2012-06-20
US9988384B2 (en) 2018-06-05
RS53788B1 (sr) 2015-06-30
CN101547924A (zh) 2009-09-30
SI2497772T1 (sl) 2015-03-31
EP2497773B1 (en) 2015-02-25
HK1175777A1 (en) 2013-07-12
KR101342014B1 (ko) 2013-12-19
AU2007322046B2 (en) 2012-04-05
CN103483343A (zh) 2014-01-01
JP5102839B2 (ja) 2012-12-19
HRP20120490T1 (hr) 2012-07-31
NO20091864L (no) 2009-06-15
MA30988B1 (fr) 2009-12-01
TW200829589A (en) 2008-07-16
PT2497772E (pt) 2015-02-05
CA2669680A1 (en) 2008-05-29
US10836766B2 (en) 2020-11-17
CY1112828T1 (el) 2016-02-10
CA2669680C (en) 2012-04-10
AU2007322046A1 (en) 2008-05-29
TWI401255B (zh) 2013-07-11
EP2944639A1 (en) 2015-11-18
KR101110458B1 (ko) 2012-03-13
GEP20125459B (en) 2012-03-26
PH12012502057B1 (en) 2018-10-24
RS52313B (sr) 2012-12-31
US20110312943A1 (en) 2011-12-22
ES2528793T3 (es) 2015-02-12
US20150166545A1 (en) 2015-06-18
KR20090091173A (ko) 2009-08-26
NZ611898A (en) 2015-01-30
JP2012006965A (ja) 2012-01-12
BRPI0718803A2 (pt) 2013-12-03
PL2086981T3 (pl) 2012-09-28
DK2497772T3 (en) 2015-01-19
DK2086981T3 (da) 2012-08-06
US20080167292A1 (en) 2008-07-10
US20240400567A1 (en) 2024-12-05
IL198690A0 (en) 2010-02-17
UA94129C2 (ru) 2011-04-11
HK1134672A1 (en) 2010-05-07
SG176443A1 (en) 2011-12-29
CR20140544A (es) 2015-01-12
CN103483343B (zh) 2016-06-01
SG10201503350TA (en) 2015-06-29
ES2537451T3 (es) 2015-06-08
EA200970486A1 (ru) 2009-10-30
EP2086981B1 (en) 2012-05-02
MX348568B (es) 2017-06-20
MX343391B (es) 2016-11-04
US9765076B2 (en) 2017-09-19
KR20110113210A (ko) 2011-10-14
NZ577042A (en) 2012-03-30
US20210214361A1 (en) 2021-07-15
ATE556076T1 (de) 2012-05-15
MY153243A (en) 2015-01-29
NO343338B1 (no) 2019-02-04
EP2497772A1 (en) 2012-09-12
JP2010510215A (ja) 2010-04-02
BRPI0718803B1 (pt) 2020-11-17
ES2384123T3 (es) 2012-06-29
BRPI0718803B8 (pt) 2021-05-25
AR064246A1 (es) 2009-03-25
PL2497772T3 (pl) 2015-05-29
WO2008063525A1 (en) 2008-05-29
US20190031662A1 (en) 2019-01-31
ZA200903279B (en) 2010-07-28
PH12012502057A1 (en) 2015-09-14
SI2086981T1 (sl) 2012-12-31
JP2014055166A (ja) 2014-03-27
EP2944639B1 (en) 2017-01-04

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