NZ589812A - Meningococcal multivalent native outer membrane vesicle vaccine, methods of making and use thereof - Google Patents

Meningococcal multivalent native outer membrane vesicle vaccine, methods of making and use thereof

Info

Publication number
NZ589812A
NZ589812A NZ589812A NZ58981209A NZ589812A NZ 589812 A NZ589812 A NZ 589812A NZ 589812 A NZ589812 A NZ 589812A NZ 58981209 A NZ58981209 A NZ 58981209A NZ 589812 A NZ589812 A NZ 589812A
Authority
NZ
New Zealand
Prior art keywords
gene
outer membrane
inactivation
pora
genetically modified
Prior art date
Application number
NZ589812A
Other languages
English (en)
Inventor
Wendell David Zollinger
Mikhail Donets
Deborah Schmiel
Boris Ionin
Ryan Marques
Elizabeth Ellen Moran
Original Assignee
U S A As Represented By The Secretary Of The Army On Behalf Of Walter Reed Army Inst Of Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by U S A As Represented By The Secretary Of The Army On Behalf Of Walter Reed Army Inst Of Res filed Critical U S A As Represented By The Secretary Of The Army On Behalf Of Walter Reed Army Inst Of Res
Publication of NZ589812A publication Critical patent/NZ589812A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/36—Adaptation or attenuation of cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NZ589812A 2008-05-30 2009-06-01 Meningococcal multivalent native outer membrane vesicle vaccine, methods of making and use thereof NZ589812A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5746208P 2008-05-30 2008-05-30
PCT/US2009/045818 WO2009158142A1 (en) 2008-05-30 2009-06-01 Meningococcal multivalent native outer membrane vesicle vaccine, methods of making and use thereof

Publications (1)

Publication Number Publication Date
NZ589812A true NZ589812A (en) 2012-08-31

Family

ID=41444870

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ589812A NZ589812A (en) 2008-05-30 2009-06-01 Meningococcal multivalent native outer membrane vesicle vaccine, methods of making and use thereof

Country Status (19)

Country Link
US (2) US9387239B2 (https=)
EP (1) EP2296699A4 (https=)
JP (2) JP5723768B2 (https=)
KR (1) KR20110053314A (https=)
CN (1) CN102105166A (https=)
AU (1) AU2009262893B2 (https=)
BR (1) BRPI0913268A2 (https=)
CA (1) CA2726465A1 (https=)
CO (1) CO6341569A2 (https=)
CR (1) CR11812A (https=)
DO (1) DOP2010000364A (https=)
EC (1) ECSP10010723A (https=)
IL (1) IL209660A0 (https=)
MX (1) MX2010012999A (https=)
NZ (1) NZ589812A (https=)
RU (1) RU2477145C2 (https=)
UA (1) UA99659C2 (https=)
WO (1) WO2009158142A1 (https=)
ZA (1) ZA201008548B (https=)

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GB0316560D0 (en) 2003-07-15 2003-08-20 Chiron Srl Vesicle filtration
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CA2792687A1 (en) * 2010-03-10 2011-09-15 Glaxosmithkline Biologicals S.A. Immunogenic composition
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AU2011300409B2 (en) 2010-09-10 2015-03-26 Wyeth Llc Non-lipidated variants of Neisseria meningitidis ORF2086 antigens
GB201015132D0 (en) * 2010-09-10 2010-10-27 Univ Bristol Vaccine composition
US9259462B2 (en) 2010-09-10 2016-02-16 Glaxosmithkline Biologicals Sa Developments in meningococcal outer membrane vesicles
US9260489B2 (en) 2011-08-31 2016-02-16 Children's Hospital & Research Center Oakland Engineered sequences to facilitate expression of antigens in Neisseria and methods of use
EP3299467B1 (en) 2012-02-02 2021-08-11 GlaxoSmithKline Biologicals SA Promoters for increased protein expression in meningococcus
US10598666B2 (en) 2012-03-08 2020-03-24 Glaxosmithkline Biologicals Sa In vitro potency assay for protein-based meningococcal vaccines
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JP6283674B2 (ja) 2012-09-18 2018-02-21 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 外膜小胞
WO2014136064A2 (en) 2013-03-08 2014-09-12 Pfizer Inc. Immunogenic fusion polypeptides
RU2662968C2 (ru) 2013-09-08 2018-07-31 Пфайзер Инк. Иммуногенная композиция против neisseria meningitidis (варианты)
WO2016132294A1 (en) 2015-02-19 2016-08-25 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
US11292808B2 (en) * 2016-01-28 2022-04-05 Intravacc B.V. Modified hexa-acylated neisserial LPS
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GB201614687D0 (en) * 2016-08-31 2016-10-12 Univ Oxford Innovation Ltd fHbp scaffold
SI3544637T1 (sl) * 2016-11-25 2021-02-26 Glaxosmithkline Biologicals S.A. Nativni OMV-antigen konjugati in njihova uporaba
AU2018215585B2 (en) 2017-01-31 2022-03-17 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
CN107151270B (zh) * 2017-03-22 2018-07-31 武汉博沃生物科技有限公司 重组ΔfHbp-NadA融合蛋白载体及其制备方法和应用
BR112021018694A2 (pt) 2019-03-21 2021-11-30 Codiak Biosciences Inc Vesículas extracelulares para distribuição de vacina
WO2021059181A1 (en) 2019-09-27 2021-04-01 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
CN113151354B (zh) * 2021-03-22 2022-03-08 中国农业科学院兰州兽医研究所 一种用于条件性敲除目的基因的载体及条件性敲除目的基因的方法
IT202400003229A1 (it) 2024-02-15 2025-08-15 Cioccio Vito Di Procedimento per la purificazione di omv da batteri gram-negativi, e relativi usi
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Also Published As

Publication number Publication date
RU2010153658A (ru) 2012-08-10
AU2009262893B2 (en) 2015-05-21
US9387239B2 (en) 2016-07-12
ECSP10010723A (es) 2011-05-31
JP2011521976A (ja) 2011-07-28
AU2009262893A1 (en) 2009-12-30
CO6341569A2 (es) 2011-11-21
CA2726465A1 (en) 2009-12-30
CR11812A (es) 2011-07-06
UA99659C2 (uk) 2012-09-10
WO2009158142A1 (en) 2009-12-30
JP5723768B2 (ja) 2015-05-27
IL209660A0 (en) 2011-02-28
CN102105166A (zh) 2011-06-22
MX2010012999A (es) 2012-03-07
EP2296699A1 (en) 2011-03-23
BRPI0913268A2 (pt) 2016-03-15
US20170100471A1 (en) 2017-04-13
DOP2010000364A (es) 2011-07-15
ZA201008548B (en) 2012-06-27
JP2015061870A (ja) 2015-04-02
AU2009262893A9 (en) 2015-05-21
US20110182942A1 (en) 2011-07-28
EP2296699A4 (en) 2013-11-13
KR20110053314A (ko) 2011-05-20
RU2477145C2 (ru) 2013-03-10

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