BRPI0913268A2 - vacina de vesícula de membrana externa nativa multivalente meningocócica, métodos de fabricação e uso da mesma - Google Patents

vacina de vesícula de membrana externa nativa multivalente meningocócica, métodos de fabricação e uso da mesma

Info

Publication number
BRPI0913268A2
BRPI0913268A2 BRPI0913268A BRPI0913268A BRPI0913268A2 BR PI0913268 A2 BRPI0913268 A2 BR PI0913268A2 BR PI0913268 A BRPI0913268 A BR PI0913268A BR PI0913268 A BRPI0913268 A BR PI0913268A BR PI0913268 A2 BRPI0913268 A2 BR PI0913268A2
Authority
BR
Brazil
Prior art keywords
manufacture
methods
outer membrane
membrane vesicle
vesicle vaccine
Prior art date
Application number
BRPI0913268A
Other languages
English (en)
Portuguese (pt)
Inventor
Boris Ionin
Deborah Schmiel
Elizabeth Ellen Moran
Mikhail Donets
Ryan Marques
Wendell David Zollinger
Original Assignee
U S A As Represented By The Secretary Of The Army On Behalf Of Walter Reed Army
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by U S A As Represented By The Secretary Of The Army On Behalf Of Walter Reed Army filed Critical U S A As Represented By The Secretary Of The Army On Behalf Of Walter Reed Army
Publication of BRPI0913268A2 publication Critical patent/BRPI0913268A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/36—Adaptation or attenuation of cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BRPI0913268A 2008-05-30 2009-06-01 vacina de vesícula de membrana externa nativa multivalente meningocócica, métodos de fabricação e uso da mesma BRPI0913268A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5746208P 2008-05-30 2008-05-30
PCT/US2009/045818 WO2009158142A1 (en) 2008-05-30 2009-06-01 Meningococcal multivalent native outer membrane vesicle vaccine, methods of making and use thereof

Publications (1)

Publication Number Publication Date
BRPI0913268A2 true BRPI0913268A2 (pt) 2016-03-15

Family

ID=41444870

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0913268A BRPI0913268A2 (pt) 2008-05-30 2009-06-01 vacina de vesícula de membrana externa nativa multivalente meningocócica, métodos de fabricação e uso da mesma

Country Status (19)

Country Link
US (2) US9387239B2 (https=)
EP (1) EP2296699A4 (https=)
JP (2) JP5723768B2 (https=)
KR (1) KR20110053314A (https=)
CN (1) CN102105166A (https=)
AU (1) AU2009262893B2 (https=)
BR (1) BRPI0913268A2 (https=)
CA (1) CA2726465A1 (https=)
CO (1) CO6341569A2 (https=)
CR (1) CR11812A (https=)
DO (1) DOP2010000364A (https=)
EC (1) ECSP10010723A (https=)
IL (1) IL209660A0 (https=)
MX (1) MX2010012999A (https=)
NZ (1) NZ589812A (https=)
RU (1) RU2477145C2 (https=)
UA (1) UA99659C2 (https=)
WO (1) WO2009158142A1 (https=)
ZA (1) ZA201008548B (https=)

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EP2544714A1 (en) * 2010-03-10 2013-01-16 GlaxoSmithKline Biologicals S.A. Vaccine composition
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SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
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AU2016221318B2 (en) 2015-02-19 2020-06-25 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
BR112018015237A2 (pt) * 2016-01-28 2018-12-26 De Staat Der Nederlanden Vert Door De Mini Van Vws Miniie Van Volksgezondheid Welzijn En Sport lps de neisseria hexa-acilado modificado
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GB201614687D0 (en) * 2016-08-31 2016-10-12 Univ Oxford Innovation Ltd fHbp scaffold
JP7165468B2 (ja) * 2016-11-25 2022-11-04 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム ｎＯＭＶ－抗原コンジュゲート及びその使用
AU2018215585B2 (en) 2017-01-31 2022-03-17 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
CN107961369B (zh) * 2017-03-22 2020-08-11 武汉博沃生物科技有限公司 多价脑膜炎球菌缀合疫苗及其制备方法
CN114080232A (zh) 2019-03-21 2022-02-22 科迪亚克生物科学公司 用于疫苗递送的细胞外囊泡
EP4034157A1 (en) 2019-09-27 2022-08-03 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
CN113151354B (zh) * 2021-03-22 2022-03-08 中国农业科学院兰州兽医研究所 一种用于条件性敲除目的基因的载体及条件性敲除目的基因的方法
IT202400003229A1 (it) 2024-02-15 2025-08-15 Cioccio Vito Di Procedimento per la purificazione di omv da batteri gram-negativi, e relativi usi
CN119020251A (zh) * 2024-08-26 2024-11-26 南昌大学 一株脂多糖修饰b群脑膜炎球菌与其外膜囊泡制备及应用

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Also Published As

Publication number Publication date
ZA201008548B (en) 2012-06-27
KR20110053314A (ko) 2011-05-20
IL209660A0 (en) 2011-02-28
AU2009262893A9 (en) 2015-05-21
WO2009158142A1 (en) 2009-12-30
US20170100471A1 (en) 2017-04-13
RU2010153658A (ru) 2012-08-10
NZ589812A (en) 2012-08-31
MX2010012999A (es) 2012-03-07
AU2009262893B2 (en) 2015-05-21
CO6341569A2 (es) 2011-11-21
AU2009262893A1 (en) 2009-12-30
EP2296699A4 (en) 2013-11-13
JP5723768B2 (ja) 2015-05-27
CN102105166A (zh) 2011-06-22
CA2726465A1 (en) 2009-12-30
US20110182942A1 (en) 2011-07-28
UA99659C2 (uk) 2012-09-10
ECSP10010723A (es) 2011-05-31
CR11812A (es) 2011-07-06
EP2296699A1 (en) 2011-03-23
JP2011521976A (ja) 2011-07-28
JP2015061870A (ja) 2015-04-02
US9387239B2 (en) 2016-07-12
RU2477145C2 (ru) 2013-03-10
DOP2010000364A (es) 2011-07-15

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