NZ582414A - Methods for generating immune response using cationic-liposome-mediated nucleic acid delivery - Google Patents

Methods for generating immune response using cationic-liposome-mediated nucleic acid delivery

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Publication number
NZ582414A
NZ582414A NZ582414A NZ58241408A NZ582414A NZ 582414 A NZ582414 A NZ 582414A NZ 582414 A NZ582414 A NZ 582414A NZ 58241408 A NZ58241408 A NZ 58241408A NZ 582414 A NZ582414 A NZ 582414A
Authority
NZ
New Zealand
Prior art keywords
nucleic acid
cationic
liposome
methods
immune response
Prior art date
Application number
NZ582414A
Other languages
English (en)
Inventor
Esther H Chang
Kathleen F Pirollo
Original Assignee
Univ Georgetown
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Georgetown filed Critical Univ Georgetown
Publication of NZ582414A publication Critical patent/NZ582414A/xx

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
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    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • C—CHEMISTRY; METALLURGY
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    • C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2810/00—Vectors comprising a targeting moiety
    • C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
    • C12N2810/80—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates
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    • C12N2810/00—Vectors comprising a targeting moiety
    • C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
    • C12N2810/80—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates
    • C12N2810/85—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian
    • C12N2810/859—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian from immunoglobulins

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  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Dispersion Chemistry (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Mycology (AREA)
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  • Biophysics (AREA)
  • Oncology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
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  • Biomedical Technology (AREA)
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  • Oil, Petroleum & Natural Gas (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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NZ582414A 2007-07-09 2008-07-09 Methods for generating immune response using cationic-liposome-mediated nucleic acid delivery NZ582414A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92968507P 2007-07-09 2007-07-09
PCT/US2008/008394 WO2009009054A1 (en) 2007-07-09 2008-07-09 Methods for generating immune response using cationic-liposome-mediated nucleic acid delivery

Publications (1)

Publication Number Publication Date
NZ582414A true NZ582414A (en) 2012-09-28

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NZ582414A NZ582414A (en) 2007-07-09 2008-07-09 Methods for generating immune response using cationic-liposome-mediated nucleic acid delivery

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Country Link
US (1) US20090053299A1 (enExample)
EP (1) EP2175835B1 (enExample)
JP (2) JP5890095B2 (enExample)
KR (2) KR101570886B1 (enExample)
CN (2) CN106890142A (enExample)
AU (1) AU2008275713B2 (enExample)
BR (1) BRPI0814558A2 (enExample)
CA (1) CA2692546C (enExample)
EA (1) EA201070050A1 (enExample)
IL (1) IL203204B (enExample)
MX (1) MX2010000166A (enExample)
NZ (1) NZ582414A (enExample)
SG (1) SG182994A1 (enExample)
WO (1) WO2009009054A1 (enExample)
ZA (1) ZA201000038B (enExample)

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RS63890B1 (sr) * 2010-08-31 2023-02-28 Glaxosmithkline Biologicals Sa Mali lipozomi za isporuku rnk koja kodira imunogen
US8932575B2 (en) 2010-09-21 2015-01-13 University Of Miami Compositions and methods for inducing migration by dendritic cells and an immune response
WO2012040266A2 (en) * 2010-09-24 2012-03-29 University Of Miami Gene-based adjuvants and compositions thereof to increase antibody production in response to gene-based vaccines
US20140120157A1 (en) 2012-09-19 2014-05-01 Georgetown University Targeted liposomes
AU2013200991B2 (en) * 2012-09-19 2015-12-10 Georgetown University Targeted liposomes
CN103405386B (zh) * 2012-09-21 2016-05-18 上海泽润生物科技有限公司 一种脂质体的制备方法及制作脂质体佐剂的方法
WO2014159917A2 (en) 2013-03-14 2014-10-02 Georgetown University Treatment for exposure to nerve agent
CN105726485B (zh) * 2016-03-24 2019-08-06 东华大学 一种半乳糖化壳聚糖修饰的免疫醇质体的制备方法
CA3121247A1 (en) 2018-12-03 2020-06-11 Board Of Regents, The University Of Texas System Oligo-benzamide analogs and their use in cancer treatment
CN111840538A (zh) * 2020-05-29 2020-10-30 中山大学 一种水痘-带状疱疹病毒亚单位纳米疫苗的制备方法和应用
WO2022051023A1 (en) * 2020-09-04 2022-03-10 Infectious Disease Research Institute Live-attenuated rna hybrid vaccine technology
CN117883382B (zh) * 2023-11-27 2025-02-14 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) 高效递送疫苗的脂质体载体及脂质体疫苗的制备与用途

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HK1143532A1 (zh) 2011-01-07
KR101570886B1 (ko) 2015-11-23
KR20100044206A (ko) 2010-04-29
IL203204B (en) 2018-05-31
US20090053299A1 (en) 2009-02-26
ZA201000038B (en) 2011-03-30
EP2175835A1 (en) 2010-04-21
CA2692546A1 (en) 2009-01-15
MX2010000166A (es) 2010-04-27
BRPI0814558A2 (pt) 2015-01-06
EA201070050A1 (ru) 2010-10-29
CN101801344A (zh) 2010-08-11
SG182994A1 (en) 2012-08-30
CN106890142A (zh) 2017-06-27
EP2175835B1 (en) 2016-04-20
AU2008275713B2 (en) 2014-08-07
KR20150108948A (ko) 2015-09-30
EP2175835A4 (en) 2011-08-03
JP5890095B2 (ja) 2016-03-22
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CA2692546C (en) 2018-03-13

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