NZ582414A - Methods for generating immune response using cationic-liposome-mediated nucleic acid delivery - Google Patents
Methods for generating immune response using cationic-liposome-mediated nucleic acid deliveryInfo
- Publication number
- NZ582414A NZ582414A NZ582414A NZ58241408A NZ582414A NZ 582414 A NZ582414 A NZ 582414A NZ 582414 A NZ582414 A NZ 582414A NZ 58241408 A NZ58241408 A NZ 58241408A NZ 582414 A NZ582414 A NZ 582414A
- Authority
- NZ
- New Zealand
- Prior art keywords
- nucleic acid
- cationic
- liposome
- methods
- immune response
- Prior art date
Links
- 239000002502 liposome Substances 0.000 title abstract 4
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- 230000028993 immune response Effects 0.000 title 1
- 230000001404 mediated effect Effects 0.000 title 1
- 125000002091 cationic group Chemical group 0.000 abstract 3
- 102000008394 Immunoglobulin Fragments Human genes 0.000 abstract 2
- 108010021625 Immunoglobulin Fragments Proteins 0.000 abstract 2
- 102000015696 Interleukins Human genes 0.000 abstract 1
- 108010063738 Interleukins Proteins 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 108010067390 Viral Proteins Proteins 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940047122 interleukins Drugs 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
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- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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- A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
- A61K47/6911—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
- A61K47/6913—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome the liposome being modified on its surface by an antibody
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- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2740/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/20011—Coronaviridae
- C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/80—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/80—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates
- C12N2810/85—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian
- C12N2810/859—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian from immunoglobulins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Dispersion Chemistry (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Biochemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Physics & Mathematics (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pulmonology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92968507P | 2007-07-09 | 2007-07-09 | |
| PCT/US2008/008394 WO2009009054A1 (en) | 2007-07-09 | 2008-07-09 | Methods for generating immune response using cationic-liposome-mediated nucleic acid delivery |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ582414A true NZ582414A (en) | 2012-09-28 |
Family
ID=40228915
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ582414A NZ582414A (en) | 2007-07-09 | 2008-07-09 | Methods for generating immune response using cationic-liposome-mediated nucleic acid delivery |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20090053299A1 (enExample) |
| EP (1) | EP2175835B1 (enExample) |
| JP (2) | JP5890095B2 (enExample) |
| KR (2) | KR101570886B1 (enExample) |
| CN (2) | CN106890142A (enExample) |
| AU (1) | AU2008275713B2 (enExample) |
| BR (1) | BRPI0814558A2 (enExample) |
| CA (1) | CA2692546C (enExample) |
| EA (1) | EA201070050A1 (enExample) |
| IL (1) | IL203204B (enExample) |
| MX (1) | MX2010000166A (enExample) |
| NZ (1) | NZ582414A (enExample) |
| SG (1) | SG182994A1 (enExample) |
| WO (1) | WO2009009054A1 (enExample) |
| ZA (1) | ZA201000038B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5573111B2 (ja) * | 2009-11-06 | 2014-08-20 | ライオン株式会社 | イソプロピルメチルフェノール含有液体口腔用組成物 |
| US20110182976A1 (en) * | 2010-01-28 | 2011-07-28 | National Taiwan Ocean University | Lipoplex-patch based dna vaccine |
| EP2540311A4 (en) * | 2010-02-26 | 2016-07-06 | Univ Nagasaki | COMPOSITE BODY FOR THE ADMINISTRATION OF ANTIGENES OR MEDICINES |
| MX341989B (es) * | 2010-08-31 | 2016-09-09 | Novartis Ag * | Liposomas pequeños para el suministro de arn que codifica el inmunogeno. |
| US8932575B2 (en) | 2010-09-21 | 2015-01-13 | University Of Miami | Compositions and methods for inducing migration by dendritic cells and an immune response |
| WO2012040266A2 (en) * | 2010-09-24 | 2012-03-29 | University Of Miami | Gene-based adjuvants and compositions thereof to increase antibody production in response to gene-based vaccines |
| US20140120157A1 (en) | 2012-09-19 | 2014-05-01 | Georgetown University | Targeted liposomes |
| JP2014062084A (ja) * | 2012-09-19 | 2014-04-10 | Georgetown Univ | 標的化されたリポソーム |
| CN103405386B (zh) * | 2012-09-21 | 2016-05-18 | 上海泽润生物科技有限公司 | 一种脂质体的制备方法及制作脂质体佐剂的方法 |
| CN105163762B (zh) * | 2013-03-14 | 2019-06-25 | 乔治敦大学 | 对神经毒剂的暴露的治疗 |
| CN105726485B (zh) * | 2016-03-24 | 2019-08-06 | 东华大学 | 一种半乳糖化壳聚糖修饰的免疫醇质体的制备方法 |
| EP3891123A4 (en) | 2018-12-03 | 2022-12-14 | Board of Regents, The University of Texas System | ANALOGS OF OLIGO-BENZAMIDE AND THEIR USE IN THE TREATMENT OF CANCER |
| CN111840538A (zh) * | 2020-05-29 | 2020-10-30 | 中山大学 | 一种水痘-带状疱疹病毒亚单位纳米疫苗的制备方法和应用 |
| CN117883382B (zh) * | 2023-11-27 | 2025-02-14 | 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) | 高效递送疫苗的脂质体载体及脂质体疫苗的制备与用途 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4957735A (en) * | 1984-06-12 | 1990-09-18 | The University Of Tennessee Research Corporation | Target-sensitive immunoliposomes- preparation and characterization |
| US4946778A (en) * | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5688488A (en) * | 1989-04-03 | 1997-11-18 | Purdue Research Foundation | Composition and method for tumor imaging |
| US5753258A (en) * | 1990-10-19 | 1998-05-19 | University Of Florida | Artificial viral envelopes |
| US6099842A (en) * | 1990-12-03 | 2000-08-08 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant immunotoxin composed of a single chain antibody reacting with the human transferrin receptor and diptheria toxin |
| DE69332485T2 (de) * | 1992-08-11 | 2003-11-13 | The President And Fellows Of Harvard College, Cambridge | Immunmodulierende peptide |
| US5786214A (en) * | 1994-12-15 | 1998-07-28 | Spinal Cord Society | pH-sensitive immunoliposomes and method of gene delivery to the mammalian central nervous system |
| FR2730637B1 (fr) * | 1995-02-17 | 1997-03-28 | Rhone Poulenc Rorer Sa | Composition pharmaceutique contenant des acides nucleiques, et ses utilisations |
| EP0873363B1 (en) * | 1995-06-14 | 2010-10-06 | The Regents of The University of California | High affinity human antibodies to tumor antigens |
| US6210707B1 (en) * | 1996-11-12 | 2001-04-03 | The Regents Of The University Of California | Methods of forming protein-linked lipidic microparticles, and compositions thereof |
| EP0956001B1 (en) * | 1996-11-12 | 2012-09-12 | The Regents of The University of California | Preparation of stable formulations of lipid-nucleic acid complexes for efficient in vivo delivery |
| US6794128B2 (en) * | 1998-04-24 | 2004-09-21 | The Regents Of The University Of California | Methods of selecting internalizing antibodies |
| US20030022854A1 (en) * | 1998-06-25 | 2003-01-30 | Dow Steven W. | Vaccines using nucleic acid-lipid complexes |
| AU3703100A (en) | 1999-02-22 | 2000-09-14 | Georgetown University | Antibody fragment-targeted immunoliposomes for systemic gene delivery |
| US7780882B2 (en) * | 1999-02-22 | 2010-08-24 | Georgetown University | Simplified and improved method for preparing an antibody or an antibody fragment targeted immunoliposome for systemic administration of a therapeutic or diagnostic agent |
| US9034329B2 (en) * | 1999-02-22 | 2015-05-19 | Georgetown University | Preparation of antibody or an antibody fragment-targeted immunoliposomes for systemic administration of therapeutic or diagnostic agents and uses thereof |
| US20020103165A1 (en) * | 2000-02-29 | 2002-08-01 | Alliance Pharmaceutical Corp., | Engineered spray-dried lipid-based microparticles for cellular targeting |
| AU2004251680B2 (en) | 2003-06-04 | 2010-02-18 | Georgetown University | Method for improving stability and shelf-life of liposome complexes |
| WO2007047981A2 (en) * | 2005-10-20 | 2007-04-26 | Georgetown University | Tumor-targeted nanodelivery systems to improve early mri detection of cancer |
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2008
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- 2008-07-09 KR KR1020107002754A patent/KR101570886B1/ko not_active Expired - Fee Related
- 2008-07-09 CA CA2692546A patent/CA2692546C/en active Active
- 2008-07-09 NZ NZ582414A patent/NZ582414A/xx not_active IP Right Cessation
- 2008-07-09 AU AU2008275713A patent/AU2008275713B2/en not_active Ceased
- 2008-07-09 BR BRPI0814558-0A2A patent/BRPI0814558A2/pt not_active Application Discontinuation
- 2008-07-09 CN CN201710070091.XA patent/CN106890142A/zh active Pending
- 2008-07-09 EP EP08780044.7A patent/EP2175835B1/en active Active
- 2008-07-09 MX MX2010000166A patent/MX2010000166A/es active IP Right Grant
- 2008-07-09 CN CN200880105375A patent/CN101801344A/zh active Pending
- 2008-07-09 KR KR1020157025507A patent/KR20150108948A/ko not_active Withdrawn
- 2008-07-09 JP JP2010516041A patent/JP5890095B2/ja not_active Expired - Fee Related
- 2008-07-09 SG SG2012049664A patent/SG182994A1/en unknown
- 2008-07-09 US US12/216,715 patent/US20090053299A1/en not_active Abandoned
- 2008-07-09 WO PCT/US2008/008394 patent/WO2009009054A1/en not_active Ceased
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Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0814558A2 (pt) | 2015-01-06 |
| KR101570886B1 (ko) | 2015-11-23 |
| EP2175835B1 (en) | 2016-04-20 |
| JP2010533178A (ja) | 2010-10-21 |
| EP2175835A4 (en) | 2011-08-03 |
| CN106890142A (zh) | 2017-06-27 |
| WO2009009054A1 (en) | 2009-01-15 |
| JP2014148533A (ja) | 2014-08-21 |
| SG182994A1 (en) | 2012-08-30 |
| IL203204B (en) | 2018-05-31 |
| JP5890095B2 (ja) | 2016-03-22 |
| CA2692546C (en) | 2018-03-13 |
| EP2175835A1 (en) | 2010-04-21 |
| HK1143532A1 (zh) | 2011-01-07 |
| AU2008275713A1 (en) | 2009-01-15 |
| MX2010000166A (es) | 2010-04-27 |
| CN101801344A (zh) | 2010-08-11 |
| AU2008275713B2 (en) | 2014-08-07 |
| US20090053299A1 (en) | 2009-02-26 |
| EA201070050A1 (ru) | 2010-10-29 |
| KR20150108948A (ko) | 2015-09-30 |
| CA2692546A1 (en) | 2009-01-15 |
| ZA201000038B (en) | 2011-03-30 |
| KR20100044206A (ko) | 2010-04-29 |
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