MX2010000166A - Metodos para generar respuesta inmune usando liberacion de acido nucleico mediada por liposoma cationico. - Google Patents

Metodos para generar respuesta inmune usando liberacion de acido nucleico mediada por liposoma cationico.

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Publication number
MX2010000166A
MX2010000166A MX2010000166A MX2010000166A MX2010000166A MX 2010000166 A MX2010000166 A MX 2010000166A MX 2010000166 A MX2010000166 A MX 2010000166A MX 2010000166 A MX2010000166 A MX 2010000166A MX 2010000166 A MX2010000166 A MX 2010000166A
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MX
Mexico
Prior art keywords
liposome
cationic
diated
methods
nucleic acid
Prior art date
Application number
MX2010000166A
Other languages
English (en)
Spanish (es)
Inventor
Esther H Chang
Kathleen F Pirollo
Original Assignee
Univ Georgetown
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Georgetown filed Critical Univ Georgetown
Publication of MX2010000166A publication Critical patent/MX2010000166A/es

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    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
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    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
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    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
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    • A61K47/6905Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
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    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
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    • A61K2039/55522Cytokines; Lymphokines; Interferons
    • A61K2039/55527Interleukins
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    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
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    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
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MX2010000166A 2007-07-09 2008-07-09 Metodos para generar respuesta inmune usando liberacion de acido nucleico mediada por liposoma cationico. MX2010000166A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92968507P 2007-07-09 2007-07-09
PCT/US2008/008394 WO2009009054A1 (en) 2007-07-09 2008-07-09 Methods for generating immune response using cationic-liposome-mediated nucleic acid delivery

Publications (1)

Publication Number Publication Date
MX2010000166A true MX2010000166A (es) 2010-04-27

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MX2010000166A MX2010000166A (es) 2007-07-09 2008-07-09 Metodos para generar respuesta inmune usando liberacion de acido nucleico mediada por liposoma cationico.

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Country Link
US (1) US20090053299A1 (enExample)
EP (1) EP2175835B1 (enExample)
JP (2) JP5890095B2 (enExample)
KR (2) KR101570886B1 (enExample)
CN (2) CN106890142A (enExample)
AU (1) AU2008275713B2 (enExample)
BR (1) BRPI0814558A2 (enExample)
CA (1) CA2692546C (enExample)
EA (1) EA201070050A1 (enExample)
IL (1) IL203204B (enExample)
MX (1) MX2010000166A (enExample)
NZ (1) NZ582414A (enExample)
SG (1) SG182994A1 (enExample)
WO (1) WO2009009054A1 (enExample)
ZA (1) ZA201000038B (enExample)

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US20110182976A1 (en) * 2010-01-28 2011-07-28 National Taiwan Ocean University Lipoplex-patch based dna vaccine
EP2540311A4 (en) * 2010-02-26 2016-07-06 Univ Nagasaki COMPOSITE BODY FOR THE ADMINISTRATION OF ANTIGENES OR MEDICINES
MX341989B (es) * 2010-08-31 2016-09-09 Novartis Ag * Liposomas pequeños para el suministro de arn que codifica el inmunogeno.
US8932575B2 (en) 2010-09-21 2015-01-13 University Of Miami Compositions and methods for inducing migration by dendritic cells and an immune response
WO2012040266A2 (en) * 2010-09-24 2012-03-29 University Of Miami Gene-based adjuvants and compositions thereof to increase antibody production in response to gene-based vaccines
US20140120157A1 (en) 2012-09-19 2014-05-01 Georgetown University Targeted liposomes
JP2014062084A (ja) * 2012-09-19 2014-04-10 Georgetown Univ 標的化されたリポソーム
CN103405386B (zh) * 2012-09-21 2016-05-18 上海泽润生物科技有限公司 一种脂质体的制备方法及制作脂质体佐剂的方法
CN105163762B (zh) * 2013-03-14 2019-06-25 乔治敦大学 对神经毒剂的暴露的治疗
CN105726485B (zh) * 2016-03-24 2019-08-06 东华大学 一种半乳糖化壳聚糖修饰的免疫醇质体的制备方法
EP3891123A4 (en) 2018-12-03 2022-12-14 Board of Regents, The University of Texas System ANALOGS OF OLIGO-BENZAMIDE AND THEIR USE IN THE TREATMENT OF CANCER
CN111840538A (zh) * 2020-05-29 2020-10-30 中山大学 一种水痘-带状疱疹病毒亚单位纳米疫苗的制备方法和应用
CN117883382B (zh) * 2023-11-27 2025-02-14 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) 高效递送疫苗的脂质体载体及脂质体疫苗的制备与用途

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