BRPI0814558A2 - Métodos para aagerar resposta imune usando liberação de ácido nucléico mediada por lipossoma catiônico - Google Patents

Métodos para aagerar resposta imune usando liberação de ácido nucléico mediada por lipossoma catiônico

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Publication number
BRPI0814558A2
BRPI0814558A2 BRPI0814558-0A2A BRPI0814558A BRPI0814558A2 BR PI0814558 A2 BRPI0814558 A2 BR PI0814558A2 BR PI0814558 A BRPI0814558 A BR PI0814558A BR PI0814558 A2 BRPI0814558 A2 BR PI0814558A2
Authority
BR
Brazil
Prior art keywords
liposoma
cationic
methods
nucleic acid
immune response
Prior art date
Application number
BRPI0814558-0A2A
Other languages
English (en)
Portuguese (pt)
Inventor
Esther H Chang
Kathleen F Pirollo
Original Assignee
Univ Georgetown
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Georgetown filed Critical Univ Georgetown
Publication of BRPI0814558A2 publication Critical patent/BRPI0814558A2/pt

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
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    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
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    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
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    • C12N2810/859—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian from immunoglobulins

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BRPI0814558-0A2A 2007-07-09 2008-07-09 Métodos para aagerar resposta imune usando liberação de ácido nucléico mediada por lipossoma catiônico BRPI0814558A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92968507P 2007-07-09 2007-07-09
PCT/US2008/008394 WO2009009054A1 (en) 2007-07-09 2008-07-09 Methods for generating immune response using cationic-liposome-mediated nucleic acid delivery

Publications (1)

Publication Number Publication Date
BRPI0814558A2 true BRPI0814558A2 (pt) 2015-01-06

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BRPI0814558-0A2A BRPI0814558A2 (pt) 2007-07-09 2008-07-09 Métodos para aagerar resposta imune usando liberação de ácido nucléico mediada por lipossoma catiônico

Country Status (15)

Country Link
US (1) US20090053299A1 (enExample)
EP (1) EP2175835B1 (enExample)
JP (2) JP5890095B2 (enExample)
KR (2) KR101570886B1 (enExample)
CN (2) CN106890142A (enExample)
AU (1) AU2008275713B2 (enExample)
BR (1) BRPI0814558A2 (enExample)
CA (1) CA2692546C (enExample)
EA (1) EA201070050A1 (enExample)
IL (1) IL203204B (enExample)
MX (1) MX2010000166A (enExample)
NZ (1) NZ582414A (enExample)
SG (1) SG182994A1 (enExample)
WO (1) WO2009009054A1 (enExample)
ZA (1) ZA201000038B (enExample)

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US8932575B2 (en) 2010-09-21 2015-01-13 University Of Miami Compositions and methods for inducing migration by dendritic cells and an immune response
WO2012040266A2 (en) * 2010-09-24 2012-03-29 University Of Miami Gene-based adjuvants and compositions thereof to increase antibody production in response to gene-based vaccines
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AU2013200991B2 (en) * 2012-09-19 2015-12-10 Georgetown University Targeted liposomes
CN103405386B (zh) * 2012-09-21 2016-05-18 上海泽润生物科技有限公司 一种脂质体的制备方法及制作脂质体佐剂的方法
WO2014159917A2 (en) 2013-03-14 2014-10-02 Georgetown University Treatment for exposure to nerve agent
CN105726485B (zh) * 2016-03-24 2019-08-06 东华大学 一种半乳糖化壳聚糖修饰的免疫醇质体的制备方法
CA3121247A1 (en) 2018-12-03 2020-06-11 Board Of Regents, The University Of Texas System Oligo-benzamide analogs and their use in cancer treatment
CN111840538A (zh) * 2020-05-29 2020-10-30 中山大学 一种水痘-带状疱疹病毒亚单位纳米疫苗的制备方法和应用
WO2022051023A1 (en) * 2020-09-04 2022-03-10 Infectious Disease Research Institute Live-attenuated rna hybrid vaccine technology
CN117883382B (zh) * 2023-11-27 2025-02-14 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） 高效递送疫苗的脂质体载体及脂质体疫苗的制备与用途

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KR101570886B1 (ko) 2015-11-23
KR20100044206A (ko) 2010-04-29
IL203204B (en) 2018-05-31
US20090053299A1 (en) 2009-02-26
ZA201000038B (en) 2011-03-30
EP2175835A1 (en) 2010-04-21
CA2692546A1 (en) 2009-01-15
MX2010000166A (es) 2010-04-27
NZ582414A (en) 2012-09-28
EA201070050A1 (ru) 2010-10-29
CN101801344A (zh) 2010-08-11
SG182994A1 (en) 2012-08-30
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EP2175835B1 (en) 2016-04-20
AU2008275713B2 (en) 2014-08-07
KR20150108948A (ko) 2015-09-30
EP2175835A4 (en) 2011-08-03
JP5890095B2 (ja) 2016-03-22
AU2008275713A1 (en) 2009-01-15
WO2009009054A1 (en) 2009-01-15
CA2692546C (en) 2018-03-13

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