EA201070050A1 - Способы индукции иммунного ответа с применением доставки нуклеиновых кислот, опосредованной катионными липосомами - Google Patents

Способы индукции иммунного ответа с применением доставки нуклеиновых кислот, опосредованной катионными липосомами

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Publication number
EA201070050A1
EA201070050A1 EA201070050A EA201070050A EA201070050A1 EA 201070050 A1 EA201070050 A1 EA 201070050A1 EA 201070050 A EA201070050 A EA 201070050A EA 201070050 A EA201070050 A EA 201070050A EA 201070050 A1 EA201070050 A1 EA 201070050A1
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Eurasian Patent Office
Prior art keywords
immune response
delivery
mediated
induction
methods
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EA201070050A
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English (en)
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Эстер Х. Чанг
Кэтлин Ф. Пиролло
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Джорджтаун Юниверсити
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Publication of EA201070050A1 publication Critical patent/EA201070050A1/ru

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Abstract

Настоящее изобретение относится к области доставки лекарственных средств и, в частности, вакцин, основанных на катионных липосомах. В своих вариантах реализации настоящее изобретение обеспечивает способы получения липосом, специфичность которых определяется лигандом (например, нацеливаемых антителом или фрагментом антитела), которые можно применять для доставки молекул для индукции иммунного ответа против вирусных антигенов или для лечения или предотвращения вирусных заболеваний. Специфичность системы доставки определяется применяемыми лигандами.
EA201070050A 2007-07-09 2008-07-09 Способы индукции иммунного ответа с применением доставки нуклеиновых кислот, опосредованной катионными липосомами EA201070050A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92968507P 2007-07-09 2007-07-09
PCT/US2008/008394 WO2009009054A1 (en) 2007-07-09 2008-07-09 Methods for generating immune response using cationic-liposome-mediated nucleic acid delivery

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EA201070050A1 true EA201070050A1 (ru) 2010-10-29

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US (1) US20090053299A1 (ru)
EP (1) EP2175835B1 (ru)
JP (2) JP5890095B2 (ru)
KR (2) KR20150108948A (ru)
CN (2) CN106890142A (ru)
AU (1) AU2008275713B2 (ru)
BR (1) BRPI0814558A2 (ru)
CA (1) CA2692546C (ru)
EA (1) EA201070050A1 (ru)
HK (1) HK1143532A1 (ru)
IL (1) IL203204B (ru)
MX (1) MX2010000166A (ru)
NZ (1) NZ582414A (ru)
SG (1) SG182994A1 (ru)
WO (1) WO2009009054A1 (ru)
ZA (1) ZA201000038B (ru)

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WO2012040101A1 (en) 2010-09-21 2012-03-29 University Of Miami Compositions and methods for inducing migration by dendritic cells and an immune response
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CN105726485B (zh) * 2016-03-24 2019-08-06 东华大学 一种半乳糖化壳聚糖修饰的免疫醇质体的制备方法
CN111840538A (zh) * 2020-05-29 2020-10-30 中山大学 一种水痘-带状疱疹病毒亚单位纳米疫苗的制备方法和应用

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NZ582414A (en) 2012-09-28
EP2175835A1 (en) 2010-04-21
JP5890095B2 (ja) 2016-03-22
KR101570886B1 (ko) 2015-11-23
SG182994A1 (en) 2012-08-30
IL203204B (en) 2018-05-31
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HK1143532A1 (zh) 2011-01-07
AU2008275713A1 (en) 2009-01-15
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AU2008275713B2 (en) 2014-08-07
US20090053299A1 (en) 2009-02-26
EP2175835A4 (en) 2011-08-03
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ZA201000038B (en) 2011-03-30
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CA2692546C (en) 2018-03-13
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