NZ572756A - Deimmunized antagonistic anti-human cd40 monoclonal antibody from the ch5d12 antibody - Google Patents

Deimmunized antagonistic anti-human cd40 monoclonal antibody from the ch5d12 antibody

Info

Publication number
NZ572756A
NZ572756A NZ572756A NZ57275607A NZ572756A NZ 572756 A NZ572756 A NZ 572756A NZ 572756 A NZ572756 A NZ 572756A NZ 57275607 A NZ57275607 A NZ 57275607A NZ 572756 A NZ572756 A NZ 572756A
Authority
NZ
New Zealand
Prior art keywords
antibody
human
deimmunized
ch5d12
antagonistic anti
Prior art date
Application number
NZ572756A
Other languages
English (en)
Inventor
Hartog Marecl Theodorus Den
Neerven Ruprecht Jules Joost Van
Kevin Stuart Johnson
Robert Duncan Casson
Original Assignee
Pangenetics Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pangenetics Bv filed Critical Pangenetics Bv
Publication of NZ572756A publication Critical patent/NZ572756A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
NZ572756A 2006-05-09 2007-05-09 Deimmunized antagonistic anti-human cd40 monoclonal antibody from the ch5d12 antibody NZ572756A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US79881906P 2006-05-09 2006-05-09
EP06076028A EP1854810A1 (en) 2006-05-09 2006-05-09 Deimmunized antagonistic anti-human CD40 monoclonal antibody from the ch5D12 antibody
PCT/NL2007/050202 WO2007129895A2 (en) 2006-05-09 2007-05-09 Deimmunized antagonistic anti-human cd40 monoclonal antibody from the ch5d12 antibody

Publications (1)

Publication Number Publication Date
NZ572756A true NZ572756A (en) 2012-10-26

Family

ID=37635851

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ572756A NZ572756A (en) 2006-05-09 2007-05-09 Deimmunized antagonistic anti-human cd40 monoclonal antibody from the ch5d12 antibody

Country Status (20)

Country Link
US (1) US8669352B2 (enExample)
EP (2) EP1854810A1 (enExample)
JP (1) JP5179474B2 (enExample)
KR (1) KR101506348B1 (enExample)
CN (1) CN101490086B (enExample)
AR (1) AR060998A1 (enExample)
AU (1) AU2007249031B9 (enExample)
BR (1) BRPI0711355A2 (enExample)
CA (1) CA2651565A1 (enExample)
CL (1) CL2007001335A1 (enExample)
DK (1) DK2019840T3 (enExample)
ES (1) ES2406163T3 (enExample)
IL (1) IL195196A (enExample)
MX (1) MX2008014304A (enExample)
NO (1) NO20085104L (enExample)
NZ (1) NZ572756A (enExample)
RU (1) RU2491295C2 (enExample)
TW (1) TWI455947B (enExample)
WO (1) WO2007129895A2 (enExample)
ZA (2) ZA200810381B (enExample)

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AR083847A1 (es) 2010-11-15 2013-03-27 Novartis Ag Variantes de fc (fragmento constante) silenciosas de los anticuerpos anti-cd40
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AU2013302441B2 (en) 2012-08-17 2018-05-10 The Regents Of The University Of Colorado, A Body Corporate Compositions and methods for detecting complement activation
US10413620B2 (en) 2012-08-17 2019-09-17 The Regents Of The University Of Colorado, A Body Corporate Light-emitting versions of the monoclonal antibody to C3D (MAB 3D29) for imaging
WO2014200349A1 (en) 2013-06-13 2014-12-18 Fast Forward Pharmaceutical B.V. Cd40 signalling inhibitor and a further compound, wherein the further compound is a bile acid, a bile acid derivative, an tgr5-receptor agonist, an fxr agonist or a combination thereof, for the treatment of chronic inflammation, and the prevention of gastrointestinal cancer or fibrosis.
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CN110382541A (zh) * 2017-03-29 2019-10-25 葛莱高托普有限公司 人源化抗cd40抗体
JP7257971B6 (ja) 2017-06-01 2023-07-24 江▲蘇▼恒瑞医▲薬▼股▲フン▼有限公司 抗cd40抗体、その抗原結合フラグメント、およびその医学的使用
WO2019087094A1 (en) 2017-11-03 2019-05-09 Novartis Ag Anti-cd40 antibodies for use in treatment of sjögren's syndrome
WO2019156565A1 (en) 2018-02-12 2019-08-15 Fast Forward Pharmaceuticals B.V. Improved antagonistic anti-human cd40 monoclonal antibodies
BR112020020277A2 (pt) 2018-04-13 2021-01-19 Novartis Ag Anticorpos anti-cd40 para uso na prevenção de rejeição de enxerto
AU2019255781A1 (en) * 2018-04-20 2020-10-29 Lyvgen Biopharma Holdings Limited Anti-CD40 antibodies and uses thereof
KR20210035805A (ko) 2018-06-15 2021-04-01 플래그쉽 파이어니어링 이노베이션스 브이, 인크. 세포후 신호전달 인자의 조절을 통한 면역 활성의 증가
KR20210070317A (ko) 2018-09-28 2021-06-14 리브젠 바이오파마 코., 엘티디. 조작된 Fc 도메인을 갖는 항-CD40 결합 분자 및 그의 치료적 용도
EP3860653A1 (en) 2018-10-05 2021-08-11 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and systems for controlling the agonistic properties of antibody variable domains by light
WO2020102454A1 (en) 2018-11-13 2020-05-22 Regents Of The University Of Minnesota Cd40 targeted peptides and uses thereof
CN112839961B (zh) 2018-11-30 2023-04-04 江苏恒瑞医药股份有限公司 一种cd40抗体药物组合物及其用途
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Also Published As

Publication number Publication date
WO2007129895A2 (en) 2007-11-15
AU2007249031A1 (en) 2007-11-15
NO20085104L (no) 2009-02-09
AR060998A1 (es) 2008-07-30
JP2009536522A (ja) 2009-10-15
CL2007001335A1 (es) 2008-01-18
DK2019840T3 (da) 2013-03-25
RU2491295C2 (ru) 2013-08-27
US20080085531A1 (en) 2008-04-10
EP1854810A1 (en) 2007-11-14
EP2019840B1 (en) 2012-12-19
IL195196A0 (en) 2011-08-01
US8669352B2 (en) 2014-03-11
TWI455947B (zh) 2014-10-11
TW200815471A (en) 2008-04-01
AU2007249031B9 (en) 2013-01-24
WO2007129895A9 (en) 2009-02-19
ZA200909185B (en) 2012-07-25
HK1131627A1 (en) 2010-01-29
ZA200810381B (en) 2010-03-31
ES2406163T3 (es) 2013-06-05
KR101506348B1 (ko) 2015-04-08
CN101490086B (zh) 2014-03-05
EP2019840A2 (en) 2009-02-04
JP5179474B2 (ja) 2013-04-10
BRPI0711355A2 (pt) 2011-09-27
CN101490086A (zh) 2009-07-22
MX2008014304A (es) 2008-11-26
IL195196A (en) 2016-02-29
KR20090029203A (ko) 2009-03-20
AU2007249031B2 (en) 2012-09-27
WO2007129895A3 (en) 2008-12-31
CA2651565A1 (en) 2007-11-15
RU2008148303A (ru) 2010-06-20

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