NZ502994A - 9-[3-Hydroxy-2-hydroxymethyl-prop-1-yl]-purine derivatives useful as antiviral agents - Google Patents

9-[3-Hydroxy-2-hydroxymethyl-prop-1-yl]-purine derivatives useful as antiviral agents

Info

Publication number
NZ502994A
NZ502994A NZ502994A NZ50299498A NZ502994A NZ 502994 A NZ502994 A NZ 502994A NZ 502994 A NZ502994 A NZ 502994A NZ 50299498 A NZ50299498 A NZ 50299498A NZ 502994 A NZ502994 A NZ 502994A
Authority
NZ
New Zealand
Prior art keywords
hydroxy
cas
methyl
purin
amino
Prior art date
Application number
NZ502994A
Other languages
English (en)
Inventor
Sebastian Mario Marcuccio
Karen Elizabeth Jarvis
Original Assignee
Commw Scient Ind Res Org
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commw Scient Ind Res Org filed Critical Commw Scient Ind Res Org
Publication of NZ502994A publication Critical patent/NZ502994A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/36—Sulfur atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NZ502994A 1997-09-11 1998-09-11 9-[3-Hydroxy-2-hydroxymethyl-prop-1-yl]-purine derivatives useful as antiviral agents NZ502994A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPO9129A AUPO912997A0 (en) 1997-09-11 1997-09-11 Antiviral agents
PCT/AU1998/000748 WO1999012927A1 (en) 1997-09-11 1998-09-11 Purine acyclonucleosides as antiviral agents

Publications (1)

Publication Number Publication Date
NZ502994A true NZ502994A (en) 2001-12-21

Family

ID=3803414

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ502994A NZ502994A (en) 1997-09-11 1998-09-11 9-[3-Hydroxy-2-hydroxymethyl-prop-1-yl]-purine derivatives useful as antiviral agents

Country Status (9)

Country Link
EP (1) EP1019404A4 (zh)
JP (1) JP2001515900A (zh)
KR (1) KR20010023890A (zh)
CN (1) CN1269801A (zh)
AU (1) AUPO912997A0 (zh)
CA (1) CA2302630A1 (zh)
ID (1) ID26937A (zh)
NZ (1) NZ502994A (zh)
WO (1) WO1999012927A1 (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI20022A (sl) * 1998-07-29 2000-02-29 Kemijski inštitut Alkilno substituirani purinovi derivati in njihova priprava
KR100377138B1 (ko) * 1998-11-10 2003-06-12 주식회사 엘지생명과학 퓨린구조를갖는싸이클린의존키나아제저해제,그제조방법및그를함유하는항암제조성물
GB9903762D0 (en) 1999-02-18 1999-04-14 Novartis Ag Organic compounds
JP2003530329A (ja) * 2000-04-07 2003-10-14 ユニヴァーシティ オブ メリーランド，ボルチモア 増大したバイオアベイラビリティを有する胆汁酸含有プロドラッグ
WO2003037860A2 (en) 2001-10-30 2003-05-08 Conforma Therapeutics Corporation Purine analogs having hsp90-inhibiting activity
AU2003279690A1 (en) * 2002-06-27 2004-01-19 F. Hoffmann-La Roche Ag Synthesis of purine derivatives
EP1615926A1 (en) * 2003-04-21 2006-01-18 Ustav Organicke Chemie A Biochemie Akademie Ved Ceske Republiky (purin-6-yl) amino acid and production method thereof
WO2005028434A2 (en) 2003-09-18 2005-03-31 Conforma Therapeutics Corporation Novel heterocyclic compounds as hsp90-inhibitors
CN101180297A (zh) 2005-03-30 2008-05-14 康福玛医药公司 作为hsp90-抑制剂的炔基吡咯并嘧啶及相关类似物
CN102002043B (zh) * 2010-11-16 2012-10-24 江苏科技大学 4-氨基吡啶催化下的6-甲氧基嘌呤衍生物的合成方法
CN102633767B (zh) * 2012-04-09 2013-10-30 武汉工程大学 一种非离子型碘造影剂中间体2－异丙基－5－羧基－1，3－二氧六环的制备方法
SI3504210T1 (sl) * 2016-08-29 2021-08-31 F. Hoffmann-La Roche Ag 7-substituirane sulfonimidoilpurinonske spojine za zdravljenje virusne okužbe in zaščito pred njo

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5216141A (en) * 1988-06-06 1993-06-01 Benner Steven A Oligonucleotide analogs containing sulfur linkages
GB8904855D0 (en) * 1989-03-03 1989-04-12 Beecham Group Plc Pharmaceutical treatment

Also Published As

Publication number Publication date
ID26937A (id) 2001-02-22
JP2001515900A (ja) 2001-09-25
AUPO912997A0 (en) 1997-10-02
CN1269801A (zh) 2000-10-11
CA2302630A1 (en) 1999-03-18
EP1019404A4 (en) 2001-07-04
EP1019404A1 (en) 2000-07-19
KR20010023890A (ko) 2001-03-26
WO1999012927A1 (en) 1999-03-18

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