NZ318843A - Processes and intermediates for preparing 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine - Google Patents

Processes and intermediates for preparing 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine

Info

Publication number
NZ318843A
NZ318843A NZ318843A NZ31884396A NZ318843A NZ 318843 A NZ318843 A NZ 318843A NZ 318843 A NZ318843 A NZ 318843A NZ 31884396 A NZ31884396 A NZ 31884396A NZ 318843 A NZ318843 A NZ 318843A
Authority
NZ
New Zealand
Prior art keywords
alkyl
preparing
compound
formula
indanon
Prior art date
Application number
NZ318843A
Other languages
English (en)
Inventor
Keith M Devries
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NZ318843A publication Critical patent/NZ318843A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
NZ318843A 1995-12-15 1996-10-11 Processes and intermediates for preparing 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine NZ318843A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US875395P 1995-12-15 1995-12-15
PCT/IB1996/001076 WO1997022584A1 (en) 1995-12-15 1996-10-11 Processes and intermediates for preparing 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine

Publications (1)

Publication Number Publication Date
NZ318843A true NZ318843A (en) 2000-01-28

Family

ID=21733469

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ318843A NZ318843A (en) 1995-12-15 1996-10-11 Processes and intermediates for preparing 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine

Country Status (33)

Country Link
EP (1) EP0883607A1 (sh)
JP (1) JP3066083B2 (sh)
KR (1) KR20000064387A (sh)
AP (1) AP708A (sh)
AR (1) AR004368A1 (sh)
AU (1) AU716462B2 (sh)
BG (1) BG102525A (sh)
BR (1) BR9612018A (sh)
CA (1) CA2237647A1 (sh)
CO (1) CO4750831A1 (sh)
CZ (1) CZ180898A3 (sh)
DZ (1) DZ2141A1 (sh)
GT (1) GT199600092A (sh)
HN (1) HN1996000065A (sh)
HR (1) HRP960592A2 (sh)
HU (1) HUP9904275A3 (sh)
IL (3) IL136421A0 (sh)
IS (1) IS4752A (sh)
MA (1) MA24032A1 (sh)
NO (1) NO982712L (sh)
NZ (1) NZ318843A (sh)
OA (1) OA10694A (sh)
PE (1) PE25698A1 (sh)
PL (1) PL197306B1 (sh)
RO (1) RO121382B1 (sh)
RU (1) RU2160731C2 (sh)
SK (1) SK75498A3 (sh)
TN (1) TNSN96153A1 (sh)
TW (1) TW414787B (sh)
UY (1) UY24401A1 (sh)
WO (1) WO1997022584A1 (sh)
YU (1) YU49486B (sh)
ZA (1) ZA9610533B (sh)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6252081B1 (en) 1998-01-16 2001-06-26 Eisai Co., Ltd. Process for production of donepezil derivative
IL125809A (en) 1998-08-17 2005-08-31 Finetech Lab Ltd Process and intermediates for production of donepezil and related compounds
US7148354B2 (en) * 2002-07-24 2006-12-12 Dr. Reddy's Laboratories Limited Process for preparation of donepezil
IL150982A (en) 2002-07-30 2007-02-11 Ori Lerman Process for making Donafzil
IL151253A0 (en) * 2002-08-14 2003-04-10 Finetech Lab Ltd Process for production of highly pure donepezil hydrochloride
US6649765B1 (en) 2003-02-12 2003-11-18 Usv Limited, Bsd Marg. Process for the preparation of 1-benzyl-4(5,6-dimethoxy-1-indanon)-2-yl) methyl piperidine hydrochloride (Donepezil HCL)
US6953856B2 (en) 2003-02-12 2005-10-11 Usv, Limited Process for the preparation of 1-benzyl-4-(5,6-dimethoxy-1-indanon)-2-yl) methyl piperidine hydrochloride (Donepezil HCI)
US20070129549A1 (en) * 2003-03-21 2007-06-07 Yatendra Kumar Stable lamotrigine pharmaceutical compositions and processes for their preparation
WO2004099142A1 (en) * 2003-05-05 2004-11-18 Ranbaxy Laboratories Limited Hydrobromide salt of benzyl-piperidylmethyl-indanone and its polymorphs
US7446203B2 (en) 2003-07-01 2008-11-04 Hetero Drugs Limited Preparation of intermediates for acetycholinesterase inhibitors
CN1280273C (zh) 2003-11-05 2006-10-18 天津和美生物技术有限公司 合成多奈哌齐及其衍生物的方法
JP2008514691A (ja) 2004-09-29 2008-05-08 ケマジス リミティド 薬学的に純粋な非晶質塩酸ドネペジルを製造するための精製されたマレイン酸ドネペジルの使用
CN100436416C (zh) * 2005-07-29 2008-11-26 西南合成制药股份有限公司 盐酸多奈哌齐合成工艺
GB0515803D0 (en) 2005-07-30 2005-09-07 Pliva Hrvatska D O O Intermediate compounds
AR057910A1 (es) 2005-11-18 2007-12-26 Synthon Bv Proceso para preparar donepezilo
NZ569532A (en) 2006-01-04 2010-11-26 Cipla Ltd Process and intermediate for preparation of donepezil
CN101626688A (zh) * 2006-12-11 2010-01-13 雷维瓦药品公司 茚满酮基胆碱酯酶抑制剂的组合物、合成和使用方法
WO2013078608A1 (en) 2011-11-29 2013-06-06 Ziqiang Gu Donepezil pamoate and methods of making and using the same
TW201540301A (zh) 2013-08-16 2015-11-01 Takeda Gmbh 以pde4抑制劑治療認知損傷

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI95572C (fi) * 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
FR2642069B1 (fr) * 1989-01-20 1991-04-12 Rhone Poulenc Sante Nouveaux derives du benzopyranne, leur preparation et les compositions pharmaceutiques qui les contiennent
DE4439822A1 (de) * 1994-11-08 1996-08-29 Bayer Ag Verfahren zur Herstellung von Benzyl-piperidylmethyl-indanonen

Also Published As

Publication number Publication date
BR9612018A (pt) 1999-02-17
RU2160731C2 (ru) 2000-12-20
AP708A (en) 1998-12-04
AU716462B2 (en) 2000-02-24
AU7092596A (en) 1997-07-14
MA24032A1 (fr) 1997-07-01
EP0883607A1 (en) 1998-12-16
IS4752A (is) 1998-05-22
NO982712D0 (no) 1998-06-12
IL136421A0 (en) 2001-06-14
UY24401A1 (es) 1997-06-09
IL124452A0 (en) 1998-12-06
RO121382B1 (ro) 2007-04-30
YU66096A (sh) 1999-11-22
HUP9904275A3 (en) 2001-05-28
TNSN96153A1 (fr) 2005-03-15
CA2237647A1 (en) 1997-06-26
DZ2141A1 (fr) 2002-07-23
JPH11500756A (ja) 1999-01-19
NO982712L (no) 1998-06-12
KR20000064387A (ko) 2000-11-06
BG102525A (en) 1999-05-31
AP9600892A0 (en) 1997-01-31
IL136420A0 (en) 2001-06-14
CZ180898A3 (cs) 1999-05-12
HUP9904275A2 (hu) 2000-05-28
ZA9610533B (en) 1998-06-15
AR004368A1 (es) 1998-11-04
PL327512A1 (en) 1998-12-21
GT199600092A (es) 1998-05-12
OA10694A (en) 2001-05-04
TW414787B (en) 2000-12-11
PL197306B1 (pl) 2008-03-31
JP3066083B2 (ja) 2000-07-17
YU49486B (sh) 2006-08-17
WO1997022584A1 (en) 1997-06-26
SK75498A3 (en) 1999-08-06
PE25698A1 (es) 1998-05-21
HN1996000065A (es) 1997-06-26
MX9804820A (es) 1998-10-31
CO4750831A1 (es) 1999-03-31
HRP960592A2 (en) 1998-06-30

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