NZ277291A - Piperidine derivatives having an alkyl substituent carrying a benzo-fused lactam - Google Patents
Piperidine derivatives having an alkyl substituent carrying a benzo-fused lactamInfo
- Publication number
- NZ277291A NZ277291A NZ277291A NZ27729194A NZ277291A NZ 277291 A NZ277291 A NZ 277291A NZ 277291 A NZ277291 A NZ 277291A NZ 27729194 A NZ27729194 A NZ 27729194A NZ 277291 A NZ277291 A NZ 277291A
- Authority
- NZ
- New Zealand
- Prior art keywords
- nitrogen
- formula
- alkyl
- radical
- piperidino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939325654A GB9325654D0 (en) | 1993-12-15 | 1993-12-15 | Cyclic amide derivatives |
| GB9423248A GB9423248D0 (en) | 1994-11-17 | 1994-11-17 | Cyclic amide derivatives |
| PCT/GB1994/002726 WO1995016682A1 (en) | 1993-12-15 | 1994-12-13 | Cyclic amide derivatives as neurokinin a antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ277291A true NZ277291A (en) | 1997-12-19 |
Family
ID=26304034
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ277291A NZ277291A (en) | 1993-12-15 | 1994-12-13 | Piperidine derivatives having an alkyl substituent carrying a benzo-fused lactam |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US5589489A (de) |
| EP (1) | EP0734383B1 (de) |
| JP (1) | JP3819934B2 (de) |
| CN (1) | CN1142822A (de) |
| AT (1) | ATE221064T1 (de) |
| AU (1) | AU690951B2 (de) |
| BR (1) | BR9408325A (de) |
| CA (1) | CA2176036A1 (de) |
| CZ (1) | CZ171796A3 (de) |
| DE (1) | DE69431069T2 (de) |
| DK (1) | DK0734383T3 (de) |
| ES (1) | ES2179094T3 (de) |
| FI (1) | FI962418A7 (de) |
| HU (1) | HUT76275A (de) |
| IL (1) | IL111970A (de) |
| NO (1) | NO962543L (de) |
| NZ (1) | NZ277291A (de) |
| PL (1) | PL315035A1 (de) |
| PT (1) | PT734383E (de) |
| SG (1) | SG52667A1 (de) |
| SK (1) | SK76396A3 (de) |
| WO (1) | WO1995016682A1 (de) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9322643D0 (en) * | 1993-11-03 | 1993-12-22 | Zeneca Ltd | Lactam derivatives |
| GB9325074D0 (en) * | 1993-12-07 | 1994-02-02 | Zeneca Ltd | Bicyclic heterocycles |
| GB9408872D0 (en) * | 1994-05-03 | 1994-06-22 | Zeneca Ltd | Heterocyclic compounds |
| US5998444A (en) * | 1995-10-24 | 1999-12-07 | Zeneca Ltd. | Piperidinyl compounds as NK1 or NK2 antagonists |
| DE69534213T2 (de) * | 1994-10-25 | 2006-01-12 | Astrazeneca Ab | Therapeutisch wirksame Heterocyclen |
| US6008223A (en) * | 1994-10-27 | 1999-12-28 | Zeneca Limited | Therapeutic compounds |
| GB9508786D0 (en) * | 1995-04-29 | 1995-06-21 | Zeneca Ltd | Substituted heterocycles |
| US5719156A (en) * | 1995-05-02 | 1998-02-17 | Schering Corporation | Piperazino derivatives as neurokinin antagonists |
| GB9521781D0 (en) * | 1995-10-24 | 1996-01-03 | Merck Sharp & Dohme | Therapeutic agents |
| GB9523526D0 (en) * | 1995-11-17 | 1996-01-17 | Zeneca Ltd | Therapeutic compounds |
| US6124319A (en) * | 1997-01-21 | 2000-09-26 | Merck & Co., Inc. | 3,3-disubstituted piperidines as modulators of chemokine receptor activity |
| JP2001508798A (ja) * | 1997-01-21 | 2001-07-03 | メルク エンド カンパニー インコーポレーテッド | ケモカインレセプター活性のモジュレーターとしての３，３−二置換ピペリジン類 |
| US6545004B1 (en) | 1999-10-27 | 2003-04-08 | Cytokinetics, Inc. | Methods and compositions utilizing quinazolinones |
| US7230000B1 (en) | 1999-10-27 | 2007-06-12 | Cytokinetics, Incorporated | Methods and compositions utilizing quinazolinones |
| US7671200B2 (en) | 1999-10-27 | 2010-03-02 | Cytokinetics, Inc. | Quinazolinone KSP inhibitors |
| US6281248B1 (en) | 2000-02-16 | 2001-08-28 | Magda Abdel Fattah Ahmed | Composition for treating asthma |
| US6846814B2 (en) | 2000-04-06 | 2005-01-25 | Astra Zeneca Ab | Neurokinin antagonists for use as medicaments |
| US20050142495A1 (en) * | 2003-10-09 | 2005-06-30 | David Peter Van Heerden | Methods of controlling multilayer foil ignition |
| US7121402B2 (en) * | 2003-04-09 | 2006-10-17 | Reactive Nano Technologies, Inc | Container hermetically sealed with crushable material and reactive multilayer material |
| US7441688B2 (en) * | 2003-11-04 | 2008-10-28 | Reactive Nanotechnologies | Methods and device for controlling pressure in reactive multilayer joining and resulting product |
| ES2299561T3 (es) | 2001-01-26 | 2008-06-01 | Btg International Limited | Analogo de bencilamina. |
| JP2005529076A (ja) | 2002-02-15 | 2005-09-29 | サイトキネティクス・インコーポレーテッド | キナゾリノンの合成 |
| CN100491358C (zh) | 2002-05-09 | 2009-05-27 | 赛特凯恩蒂克公司 | 嘧啶酮类化合物、组合物及方法 |
| US7214800B2 (en) | 2002-05-09 | 2007-05-08 | Cytokinetics, Inc. | Compounds, compositions, and methods |
| JP2005536475A (ja) | 2002-05-23 | 2005-12-02 | サイトキネティクス・インコーポレーテッド | 化合物、組成物、および方法 |
| US7041676B2 (en) | 2002-06-14 | 2006-05-09 | Cytokinetics, Inc. | Compounds, compositions, and methods |
| AU2003256805A1 (en) | 2002-07-23 | 2004-02-09 | Cytokinetics, Inc. | Compounds compositions and methods |
| WO2004034972A2 (en) | 2002-09-30 | 2004-04-29 | Cytokinetics, Inc. | Compounds, compositions, and methods |
| JO2696B1 (en) * | 2002-12-23 | 2013-03-03 | شركة جانسين فارماسوتيكا ان. في | Derivatives of 1-piperdine-4-yl-4-biprolidine-3-yl-piperazine substituted and used as quinine antagonists |
| AU2004256020A1 (en) * | 2003-05-13 | 2005-01-20 | Johns Hopkins University | Method of controlling thermal waves in reactive multilayer joining and resulting product |
| US7439254B2 (en) | 2003-12-08 | 2008-10-21 | Cytokinetics, Inc. | Compounds, compositions, and methods |
| JP2008503482A (ja) | 2004-06-18 | 2008-02-07 | ワイス | ６−アルキル−５−アリールスルホニル−ジヒドロフェナントリジンの製造方法 |
| CA2877826C (en) | 2012-07-09 | 2016-08-16 | Lupin Limited | Tetrahydroquinazolinone derivatives as parp inhibitors |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE903957A1 (en) * | 1989-11-06 | 1991-05-08 | Sanofi Sa | Aromatic amine compounds, their method of preparation and¹pharmaceutical compositions in which they are present |
| FR2654725B1 (fr) * | 1989-11-23 | 1992-02-14 | Rhone Poulenc Sante | Nouveaux derives de l'isoindolone, leur preparation et les compositions pharmaceutiques qui les contiennent. |
| IL99320A (en) * | 1990-09-05 | 1995-07-31 | Sanofi Sa | Arylalkylamines, their preparation and pharmaceutical compositions containing them |
| FR2676055B1 (fr) * | 1991-05-03 | 1993-09-03 | Sanofi Elf | Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| FR2676053B1 (fr) * | 1991-05-03 | 1993-08-27 | Sanofi Elf | Nouveaux composes dialkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| FR2676054B1 (fr) * | 1991-05-03 | 1993-09-03 | Sanofi Elf | Nouveaux composes n-alkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| FR2688219B1 (fr) * | 1992-03-03 | 1994-07-08 | Sanofi Elf | Sels d'ammonium quaternaires de composes aromatiques amines, leur preparation et compositions pharmaceutiques les contenant. |
| GB9321557D0 (en) * | 1992-11-03 | 1993-12-08 | Zeneca Ltd | Carboxamide derivatives |
| GB9310066D0 (en) * | 1993-05-17 | 1993-06-30 | Zeneca Ltd | Alkyl substituted heterocycles |
| GB9310713D0 (en) * | 1993-05-24 | 1993-07-07 | Zeneca Ltd | Aryl substituted heterocycles |
| JPH08511522A (ja) * | 1993-06-07 | 1996-12-03 | メルク エンド カンパニー インコーポレーテッド | ニューロキニンアンタゴニストとしてのスピロ置換アザ環 |
| GB9317104D0 (en) * | 1993-08-17 | 1993-09-29 | Zeneca Ltd | Therapeutic heterocycles |
| GB9322643D0 (en) * | 1993-11-03 | 1993-12-22 | Zeneca Ltd | Lactam derivatives |
-
1994
- 1994-12-12 US US08/353,767 patent/US5589489A/en not_active Expired - Lifetime
- 1994-12-13 EP EP95903415A patent/EP0734383B1/de not_active Expired - Lifetime
- 1994-12-13 SG SG1996007599A patent/SG52667A1/en unknown
- 1994-12-13 AT AT95903415T patent/ATE221064T1/de not_active IP Right Cessation
- 1994-12-13 PL PL94315035A patent/PL315035A1/xx unknown
- 1994-12-13 AU AU12471/95A patent/AU690951B2/en not_active Ceased
- 1994-12-13 DE DE69431069T patent/DE69431069T2/de not_active Expired - Fee Related
- 1994-12-13 ES ES95903415T patent/ES2179094T3/es not_active Expired - Lifetime
- 1994-12-13 BR BR9408325A patent/BR9408325A/pt not_active Application Discontinuation
- 1994-12-13 DK DK95903415T patent/DK0734383T3/da active
- 1994-12-13 SK SK763-96A patent/SK76396A3/sk unknown
- 1994-12-13 CZ CZ961717A patent/CZ171796A3/cs unknown
- 1994-12-13 PT PT95903415T patent/PT734383E/pt unknown
- 1994-12-13 IL IL11197094A patent/IL111970A/en not_active IP Right Cessation
- 1994-12-13 CA CA002176036A patent/CA2176036A1/en not_active Abandoned
- 1994-12-13 JP JP51660295A patent/JP3819934B2/ja not_active Expired - Fee Related
- 1994-12-13 CN CN94194944A patent/CN1142822A/zh active Pending
- 1994-12-13 FI FI962418A patent/FI962418A7/fi unknown
- 1994-12-13 WO PCT/GB1994/002726 patent/WO1995016682A1/en not_active Ceased
- 1994-12-13 NZ NZ277291A patent/NZ277291A/en unknown
- 1994-12-13 HU HU9601568A patent/HUT76275A/hu unknown
-
1996
- 1996-06-14 NO NO962543A patent/NO962543L/no unknown
- 1996-09-26 US US08/717,999 patent/US5705505A/en not_active Expired - Fee Related
-
1997
- 1997-11-26 US US08/980,399 patent/US5965576A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5589489A (en) | 1996-12-31 |
| BR9408325A (pt) | 1997-08-19 |
| DK0734383T3 (da) | 2002-10-14 |
| AU1247195A (en) | 1995-07-03 |
| SG52667A1 (en) | 1998-09-28 |
| FI962418L (fi) | 1996-06-11 |
| NO962543D0 (no) | 1996-06-14 |
| DE69431069D1 (de) | 2002-08-29 |
| CN1142822A (zh) | 1997-02-12 |
| CA2176036A1 (en) | 1995-06-22 |
| ES2179094T3 (es) | 2003-01-16 |
| EP0734383B1 (de) | 2002-07-24 |
| AU690951B2 (en) | 1998-05-07 |
| DE69431069T2 (de) | 2003-05-08 |
| WO1995016682A1 (en) | 1995-06-22 |
| JPH09506608A (ja) | 1997-06-30 |
| ATE221064T1 (de) | 2002-08-15 |
| HUT76275A (en) | 1997-07-28 |
| CZ171796A3 (en) | 1996-09-11 |
| US5705505A (en) | 1998-01-06 |
| FI962418A0 (fi) | 1996-06-11 |
| PL315035A1 (en) | 1996-09-30 |
| US5965576A (en) | 1999-10-12 |
| HU9601568D0 (en) | 1996-08-28 |
| EP0734383A1 (de) | 1996-10-02 |
| IL111970A0 (en) | 1995-03-15 |
| NO962543L (no) | 1996-08-14 |
| SK76396A3 (en) | 1996-12-04 |
| FI962418A7 (fi) | 1996-06-11 |
| PT734383E (pt) | 2002-12-31 |
| IL111970A (en) | 1999-03-12 |
| JP3819934B2 (ja) | 2006-09-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NZ277291A (en) | Piperidine derivatives having an alkyl substituent carrying a benzo-fused lactam | |
| US5710169A (en) | Therapeutic heterocycles | |
| EP0630887B1 (de) | 4-(Aryl-substituierte)-Piperidine als Neurokinin-Receptor Antagonisten | |
| US6124279A (en) | Therapeutic heterocycles | |
| US5731309A (en) | Substituted heteroalkyleneamine neurokinin antagonists | |
| US6147083A (en) | Azospiro compounds as NK1 or NK2 antagonists | |
| CZ209398A3 (cs) | 3-Azetidinylalkylpiperidiny a pyrrolidiny, způsob a meziprodukty pro jejich výrobu, farmaceutické prostředky na jejich bázi a použití těchto látek | |
| US5739149A (en) | Substituted piperidinobutyl nitrogen-containing heterocyclic compounds and analogues thereof as neurokinin antagonists | |
| US5977135A (en) | Bicyclic heterocycles | |
| US5889024A (en) | Substituted heterocycles | |
| EP1641756B1 (de) | 4-arylsulphonylpiperidin-derivate als 5-ht2a -rezeptor antagonisten | |
| US6008223A (en) | Therapeutic compounds | |
| FI85693B (fi) | Foerfarande foer framstaellning av nya hydropyridinderivat. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RENW | Renewal (renewal fees accepted) |