NZ254267A - Animal vaccines comprising a pseudorabies virus having a mutation in its gp50 gene - Google Patents

Animal vaccines comprising a pseudorabies virus having a mutation in its gp50 gene

Info

Publication number
NZ254267A
NZ254267A NZ254267A NZ25426793A NZ254267A NZ 254267 A NZ254267 A NZ 254267A NZ 254267 A NZ254267 A NZ 254267A NZ 25426793 A NZ25426793 A NZ 25426793A NZ 254267 A NZ254267 A NZ 254267A
Authority
NZ
New Zealand
Prior art keywords
virus
gene
mutants
vaccine
virol
Prior art date
Application number
NZ254267A
Other languages
English (en)
Inventor
Bernardus Petrus Huber Peeters
Jan Maria Antonius Pol
Arnold Leonard Josef Gielkens
Robertus Jacobus Mari Moormann
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of NZ254267A publication Critical patent/NZ254267A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/245Herpetoviridae, e.g. herpes simplex virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/543Mucosal route intranasal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16711Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16722New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16711Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16734Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16711Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16761Methods of inactivation or attenuation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
NZ254267A 1992-07-09 1993-07-08 Animal vaccines comprising a pseudorabies virus having a mutation in its gp50 gene NZ254267A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP92202096 1992-07-09

Publications (1)

Publication Number Publication Date
NZ254267A true NZ254267A (en) 1996-08-27

Family

ID=8210764

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ254267A NZ254267A (en) 1992-07-09 1993-07-08 Animal vaccines comprising a pseudorabies virus having a mutation in its gp50 gene

Country Status (18)

Country Link
US (1) US5674500A (https=)
EP (1) EP0654086B1 (https=)
JP (1) JPH07509127A (https=)
KR (1) KR100341994B1 (https=)
CN (1) CN1124159C (https=)
AT (1) ATE189000T1 (https=)
AU (1) AU684252B2 (https=)
CA (1) CA2139507C (https=)
DE (1) DE69327656T2 (https=)
DK (1) DK0654086T3 (https=)
ES (1) ES2143507T3 (https=)
HU (1) HU220099B (https=)
NZ (1) NZ254267A (https=)
PL (1) PL174219B1 (https=)
RU (1) RU2158308C2 (https=)
TW (1) TW289731B (https=)
WO (1) WO1994001573A1 (https=)
ZA (1) ZA934882B (https=)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3128133B2 (ja) * 1991-06-06 2001-01-29 スティッチティング セントラール ディールゲネースクンディグ インスティトゥート 豚の奇病の原因体であるレリスタドエイジェント、それを含むワクチン組成物、豚の奇病の診断キット及び診断方法
US6007825A (en) * 1991-12-23 1999-12-28 American Cyanamid Company Serpulina hyodysenteriae vaccine comprising a tly gene mutant
US7223411B1 (en) * 1992-07-31 2007-05-29 Dana-Farber Cancer Institute Herpesvirus replication defective mutants
US6773908B1 (en) * 1992-10-30 2004-08-10 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US6380376B1 (en) * 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
US6592873B1 (en) 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
EP0689603A1 (en) * 1993-03-19 1996-01-03 Cantab Pharmaceuticals Research Limited Defective mutant non-retroviral virus (e.g. hsv) as vaccine
EP0659885A1 (en) * 1993-12-21 1995-06-28 Akzo Nobel N.V. Vaccine against viruses associated with antibody-dependent-enhancement of viral infectivity
EP0693551A1 (en) * 1994-07-18 1996-01-24 Akzo Nobel N.V. gD-negative bovine herpesvirus mutant, capable of direct cell-to-cell transmission
EP0839912A1 (en) * 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
US20040224327A1 (en) * 1996-10-30 2004-11-11 Meulenberg Johanna Jacoba Maria Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
US6399354B1 (en) 1998-07-31 2002-06-04 President And Fellows Of Harvard College Replication-competent virus expressing a detectable fusion protein
EP1157121B1 (en) * 1999-03-08 2013-04-24 Boehringer Ingelheim Vetmedica GmbH Prrsv replicon
DK2251419T3 (da) * 1999-04-22 2012-07-02 Us Agriculture Porcint reproduktions- og respirations-syndrom-vaccine baseret på isolat JA-142
US20050014264A1 (en) * 2002-12-11 2005-01-20 University Of Massachusetts Method of introducing siRNA into adipocytes
AU2005265142A1 (en) * 2004-06-18 2006-01-26 Regents Of The University Of Minnesota Identifying virally infected and vaccinated organisms
US7632636B2 (en) * 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
PL2369001T3 (pl) 2005-06-24 2017-06-30 Regents Of The University Of Minnesota Wirusy PRRS, ich klony zakaźne, mutanty i sposoby stosowania
CN101081298A (zh) * 2007-06-26 2007-12-05 陈少莺 一种猪伪狂犬病新型亚单位疫苗制备方法
EP2328612A4 (en) * 2008-08-25 2012-11-14 Boehringer Ingelheim Vetmed VACCINE AGAINST HIGH PATHOGENIC DISEASED LATE LIVESTOCK (PRRS)
CN101457215B (zh) * 2008-12-01 2010-11-17 华中农业大学 重组猪伪狂犬病毒-猪繁殖与呼吸综合征病毒-猪圆环病毒基因工程毒株及应用
TWI627281B (zh) * 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 降低pcv-2組合物殺病毒活性之方法及具有改良免疫原性之pcv-2組合物
RU2439150C1 (ru) * 2010-11-16 2012-01-10 Государственное научное учреждение Всероссийский научно-исследовательский институт ветеринарной вирусологии и микробиологии Штамм "ас-21/07" вируса ауески для изготовления вакцинных и диагностических препаратов
PH12013501708B1 (en) 2011-02-17 2018-08-03 Boehringer Ingelheim Vetmedica Gmbh Commercial scale process for production of prrsv
HRP20151031T1 (hr) 2011-02-17 2015-11-06 Boehringer Ingelheim Vetmedica Gmbh Novi europski soj prrsv
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
WO2013017568A1 (en) 2011-07-29 2013-02-07 Boehringer Ingelheim Vetmedica Gmbh INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF
CN105073130A (zh) 2013-03-15 2015-11-18 勃林格殷格翰动物保健公司 猪生殖与呼吸综合征病毒、组合物、疫苗及使用方法
CN104250640A (zh) * 2014-08-22 2014-12-31 普莱柯生物工程股份有限公司 猪伪狂犬病病毒基因缺失株、疫苗组合物及其制备方法和应用
CN105087506B (zh) * 2015-03-20 2020-06-30 普莱柯生物工程股份有限公司 一种猪伪狂犬病病毒致弱方法、及其致弱的病毒株、疫苗组合物和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4859587A (en) * 1984-06-04 1989-08-22 Institut Merieux Recombinant herpes simplex viruses, vaccines and methods
KR950000887B1 (ko) * 1985-07-29 1995-02-03 디 엎죤 캄파니 프로제니터 비루스 왁찐 조성물, 이의 제조방법, 및 이를 사용하여 비루스에 감염된 동물과 왁찐 주사를 맞은 동물을 구별하기 위한 방법
US5352575A (en) * 1985-10-04 1994-10-04 The Upjohn Company Pseudorabies virus protein
US4999296A (en) * 1986-04-29 1991-03-12 Novagene, Inc. Thymidine kinase negative insertion mutants of pseudorabies virus and methods for the production of same
NL8902087A (nl) * 1989-08-17 1991-03-18 Stichting Tech Wetenschapp Niet-natuurlijk voorkomend pseudorabiesvirus en vaccins die dit bevatten.
WO1992005263A1 (en) * 1990-09-25 1992-04-02 Cantab Pharmaceuticals Research Limited Viral defective vaccine produced by transcomplementing cell line
AU4560693A (en) * 1992-07-30 1994-03-03 Akzo Nobel N.V. Non-shedding live herpesvirus vaccine

Also Published As

Publication number Publication date
HU220099B (hu) 2001-10-28
CN1086143A (zh) 1994-05-04
TW289731B (https=) 1996-11-01
RU2158308C2 (ru) 2000-10-27
AU684252B2 (en) 1997-12-11
CN1124159C (zh) 2003-10-15
CA2139507A1 (en) 1994-01-20
CA2139507C (en) 2005-04-19
PL307049A1 (en) 1995-05-02
KR100341994B1 (ko) 2002-11-30
PL174219B1 (pl) 1998-06-30
ZA934882B (en) 1994-02-03
ATE189000T1 (de) 2000-02-15
WO1994001573A1 (en) 1994-01-20
EP0654086B1 (en) 2000-01-19
HU9500039D0 (en) 1995-03-28
DE69327656T2 (de) 2000-08-03
DE69327656D1 (de) 2000-02-24
US5674500A (en) 1997-10-07
ES2143507T3 (es) 2000-05-16
DK0654086T3 (da) 2000-06-13
JPH07509127A (ja) 1995-10-12
HUT70986A (en) 1995-11-28
AU4589893A (en) 1994-01-31
EP0654086A1 (en) 1995-05-24
RU95105518A (ru) 1997-03-27

Similar Documents

Publication Publication Date Title
EP0654086B1 (en) Vaccines against aujeszky's disease and other animal diseases containing pseudorabies virus mutants
DK172285B1 (da) Deletionsmutant af et herpesvirus og vaccine indeholdende dette virus
US6387376B1 (en) Recombinant vaccine containing feline herpes virus type 1 particularly for treating feline infectious peritonitis
JP2000512844A (ja) ベクターとして鳥類の感染性喉頭気管炎ウイルスを用いた鳥類用組換え生ワクチン
JP2000512264A (ja) カレ病、狂犬病、タイプ2のパラインフルエンザに対するイヌヘルペスウイルスをベースにした組換え生ワクチン
US5626850A (en) Non-shedding live herpesvirus vaccine
US7060282B1 (en) Attenuated equine herpesvirus
JP3529134B2 (ja) 組換えネコヘルペスウイルスのベクターワクチン
NZ253188A (en) Vaccines and mutants in relation to infectious bovine rhinotracheitis virus
NL8902087A (nl) Niet-natuurlijk voorkomend pseudorabiesvirus en vaccins die dit bevatten.
WO1995007987A2 (en) Novel proteins/polypeptides and cotransfection plasmids and live recombinant carriers therefor
AU738684B2 (en) Recombinant equine herpesvirus type 1 (EHV-1) comprising a dysfunctional gene 71 region and use thereof as a vaccine
AU784310B2 (en) Recombinant infectious laryngotracheitis virus vaccine
WO1998003635A1 (en) Regions nonessential for the proliferation of avipoxviruses, and recombinant avipoxviruses and vaccines prepared with the use of the same
US20020155131A1 (en) Recombinant equine herpesvirus type 1 (EHV-1) comprising a dysfunctional gene 71 region and use thereof as a vaccine
WO1998004710A9 (en) Live recombinant bhv/brsv vaccine
WO1998004710A2 (en) Live recombinant bhv/brsv vaccine

Legal Events

Date Code Title Description
RENW Renewal (renewal fees accepted)