NZ243180A - Aromatic ether derivatives and antiviral compositions thereof - Google Patents

Aromatic ether derivatives and antiviral compositions thereof

Info

Publication number
NZ243180A
NZ243180A NZ243180A NZ24318092A NZ243180A NZ 243180 A NZ243180 A NZ 243180A NZ 243180 A NZ243180 A NZ 243180A NZ 24318092 A NZ24318092 A NZ 24318092A NZ 243180 A NZ243180 A NZ 243180A
Authority
NZ
New Zealand
Prior art keywords
compound
formula
ch3o
compounds
alkoxy
Prior art date
Application number
NZ243180A
Other languages
English (en)
Inventor
Viyyoor M Girijavallabhan
Ashit K Ganguly
Richard W Versace
Anil K Saksena
Patrick A Pinto
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Priority to NZ270131A priority Critical patent/NZ270131A/en
Publication of NZ243180A publication Critical patent/NZ243180A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/92—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with etherified hydroxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D263/14—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/28—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/42—Singly bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicinal Preparation (AREA)
NZ243180A 1991-06-19 1992-06-17 Aromatic ether derivatives and antiviral compositions thereof NZ243180A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NZ270131A NZ270131A (en) 1991-06-19 1992-06-17 Orally active antiviral aromatic ether compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71745191A 1991-06-19 1991-06-19

Publications (1)

Publication Number Publication Date
NZ243180A true NZ243180A (en) 1995-08-28

Family

ID=24882086

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ243180A NZ243180A (en) 1991-06-19 1992-06-17 Aromatic ether derivatives and antiviral compositions thereof

Country Status (23)

Country Link
US (4) US5559133A (enExample)
EP (2) EP0519702A1 (enExample)
JP (1) JP2625258B2 (enExample)
KR (1) KR960004887B1 (enExample)
AT (1) ATE182874T1 (enExample)
AU (1) AU674657B2 (enExample)
CA (1) CA2111854C (enExample)
CZ (1) CZ279793A3 (enExample)
DE (1) DE69229733T2 (enExample)
ES (1) ES2134808T3 (enExample)
FI (1) FI935690A0 (enExample)
IE (1) IE921971A1 (enExample)
IL (1) IL102241A0 (enExample)
MX (1) MX9203068A (enExample)
MY (1) MY107993A (enExample)
NZ (1) NZ243180A (enExample)
OA (1) OA09828A (enExample)
PL (1) PL169699B1 (enExample)
SK (1) SK144293A3 (enExample)
TW (1) TW260658B (enExample)
WO (1) WO1992022520A1 (enExample)
YU (1) YU63392A (enExample)
ZA (1) ZA924445B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0519702A1 (en) * 1991-06-19 1992-12-23 Schering Corporation Orally active antiviral compounds
AU691490B2 (en) * 1993-02-26 1998-05-21 Schering Corporation Use of 2-chloro-1-{{4-{(2,6-dichlorophenoxy)methyl}-phenyl}methoxy} -4-methoxy-benzene for the selective treatment of enteroviral infections in humans
AU6783698A (en) * 1997-04-10 1998-10-30 Pharmacia & Upjohn Company Polyaromatic antiviral compositions
AU6462500A (en) * 1999-07-29 2001-02-19 Patrick T. Prendergast Dithiolthione compounds for the treatment of neurological disorders and for memory enhancement

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2418571A1 (de) * 1973-04-18 1974-11-14 Ciba Geigy Ag Phenyl-aralkyl-aether, diphenyle und benzophenone, verfahren zu ihrer herstellung und ihre verwendung
JPS509785A (enExample) * 1973-05-31 1975-01-31
JPS5922697B2 (ja) * 1976-01-13 1984-05-28 エーザイ株式会社 ビス−（メタ−アミジノフエノキシ）−化合物
JPS5651423A (en) * 1979-09-13 1981-05-09 Wellcome Found Antiviral agent
EP0099933B1 (en) * 1982-01-29 1986-04-02 Toray Industries, Inc. Process for preparing alpha,omega-bis(2-chlorophenoxy)-alkane-4,4'-dicarboxylic acid or its lower alkyl ester
US4851423A (en) * 1986-12-10 1989-07-25 Schering Corporation Pharmaceutically active compounds
JPH0621083B2 (ja) * 1986-12-22 1994-03-23 株式会社三光開発科学研究所 ジ（アリ−ルオキシ）アルカンの製造方法
US4891449A (en) * 1988-06-30 1990-01-02 Great Lakes Chemical Corporation Halogenated unsymmetrical higher alkyl phenoxy alkanes
AU6062590A (en) * 1989-07-07 1991-02-06 Schering Corporation Pharmaceutically active compounds
EP0519702A1 (en) * 1991-06-19 1992-12-23 Schering Corporation Orally active antiviral compounds

Also Published As

Publication number Publication date
CA2111854C (en) 2001-01-09
DE69229733D1 (de) 1999-09-09
US5350772A (en) 1994-09-27
CZ279793A3 (en) 1994-05-18
TW260658B (enExample) 1995-10-21
PL169699B1 (en) 1996-08-30
EP0519702A1 (en) 1992-12-23
YU63392A (sh) 1994-11-15
ATE182874T1 (de) 1999-08-15
OA09828A (en) 1994-04-15
WO1992022520A1 (en) 1992-12-23
US5618849A (en) 1997-04-08
ZA924445B (en) 1993-02-24
EP0590026B1 (en) 1999-08-04
US5449782A (en) 1995-09-12
FI935690A7 (fi) 1993-12-17
AU2221392A (en) 1993-01-12
DE69229733T2 (de) 1999-12-02
JPH06503839A (ja) 1994-04-28
FI935690A0 (fi) 1993-12-17
JP2625258B2 (ja) 1997-07-02
AU674657B2 (en) 1997-01-09
KR960004887B1 (ko) 1996-04-16
MY107993A (en) 1996-07-15
EP0590026A1 (en) 1994-04-06
CA2111854A1 (en) 1992-12-23
US5559133A (en) 1996-09-24
IL102241A0 (en) 1993-01-14
MX9203068A (es) 1993-07-01
ES2134808T3 (es) 1999-10-16
IE921971A1 (en) 1992-12-30
SK144293A3 (en) 1994-06-08

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