NZ238426A - Phenyl-methylene-thio (or -sulphinyl, -sulphonyl, -amino or -methylamino) substituted pyridine derivatives and medicaments - Google Patents

Phenyl-methylene-thio (or -sulphinyl, -sulphonyl, -amino or -methylamino) substituted pyridine derivatives and medicaments

Info

Publication number
NZ238426A
NZ238426A NZ238426A NZ23842691A NZ238426A NZ 238426 A NZ238426 A NZ 238426A NZ 238426 A NZ238426 A NZ 238426A NZ 23842691 A NZ23842691 A NZ 23842691A NZ 238426 A NZ238426 A NZ 238426A
Authority
NZ
New Zealand
Prior art keywords
compound
aliphatic
pyridyl
phenyl
pharmaceutically acceptable
Prior art date
Application number
NZ238426A
Other languages
English (en)
Inventor
Robert A Daines
William D Kingsbury
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of NZ238426A publication Critical patent/NZ238426A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/65One oxygen atom attached in position 3 or 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NZ238426A 1990-06-07 1991-06-06 Phenyl-methylene-thio (or -sulphinyl, -sulphonyl, -amino or -methylamino) substituted pyridine derivatives and medicaments NZ238426A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53439790A 1990-06-07 1990-06-07

Publications (1)

Publication Number Publication Date
NZ238426A true NZ238426A (en) 1994-11-25

Family

ID=24129867

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ238426A NZ238426A (en) 1990-06-07 1991-06-06 Phenyl-methylene-thio (or -sulphinyl, -sulphonyl, -amino or -methylamino) substituted pyridine derivatives and medicaments

Country Status (17)

Country Link
EP (1) EP0593464A1 (fr)
JP (1) JPH07116150B2 (fr)
KR (1) KR930700102A (fr)
CN (1) CN1058015A (fr)
AU (1) AU655428B2 (fr)
CA (1) CA2083957A1 (fr)
FI (1) FI925545A (fr)
HU (1) HUT64747A (fr)
IL (1) IL98387A0 (fr)
MA (1) MA22195A1 (fr)
MX (1) MX26167A (fr)
NZ (1) NZ238426A (fr)
PL (1) PL290587A1 (fr)
PT (1) PT97913A (fr)
TW (1) TW221809B (fr)
WO (1) WO1991018601A1 (fr)
ZA (1) ZA914322B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0604529A1 (fr) * 1991-09-19 1994-07-06 Smithkline Beecham Corporation Composes de pyridine utilises dans le traitement des maladies apparentees aux leucotrienes
IL106156A0 (en) * 1992-06-30 1993-10-20 Smithkline Beecham Corp Pyridinyl compounds
CN1095713A (zh) * 1992-06-30 1994-11-30 史密丝克莱恩比彻姆公司 制造某些硫醚的方法
DE4224402A1 (de) * 1992-07-21 1994-01-27 Schering Ag Neue Pyridin-Derivate mit Leukotrien-B¶4¶-antagonistischer Wirkung
GR1001409B (el) * 1992-10-15 1993-11-30 Smithkline Beecham Corp Ενώσεις για την ?εραπευτική αγωγή ασ?ενειών που έχουν σχέση με λευκοτριένια.
ES2065234B1 (es) * 1992-10-27 1995-09-01 Smithkline Beecham Corp Compuestos para tratar enfermedades relacionadas con los leucotrienos.
US5643914A (en) * 1993-03-02 1997-07-01 Smithkline Beecham Corporation Pharmaceutical pyridine compounds
US5929096A (en) * 1996-02-29 1999-07-27 Smithkline Beecham Corporation Method for treating atopic dermatitis and contact dermatitis
CA2265996A1 (fr) 1996-09-26 1998-04-02 Roger Aki Fujimoto Acrylamides substitues par de l'aryle ayant une activite antagoniste du recepteur leucotriene b4 (ltb-4)
PL2520654T3 (pl) 2003-08-26 2017-08-31 The Regents Of The University Of Colorado, A Body Corporate Inhibitory aktywności proteazy serynowej i ich zastosowanie w sposobach i kompozycjach do leczenia zakażeń bakteryjnych
EP3812363B1 (fr) * 2018-06-22 2022-08-03 Panasonic Holdings Corporation Sel organique, capteur de radicaux hydroxy le comprenant, et milieu de détection

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4056619A (en) * 1975-09-08 1977-11-01 Warner-Lambert Company 1-Substituted-2-(2-pyridinyl)ethanone N-oxides

Also Published As

Publication number Publication date
ZA914322B (en) 1992-06-24
AU655428B2 (en) 1994-12-22
PL290587A1 (en) 1992-08-24
EP0593464A4 (fr) 1993-02-12
FI925545A0 (fi) 1992-12-07
CA2083957A1 (fr) 1991-12-08
CN1058015A (zh) 1992-01-22
MX26167A (es) 1994-02-28
HU9203867D0 (en) 1993-03-29
PT97913A (pt) 1992-03-31
HUT64747A (en) 1994-02-28
JPH05507492A (ja) 1993-10-28
MA22195A1 (fr) 1992-04-01
IL98387A0 (en) 1992-07-15
FI925545A (fi) 1992-12-07
TW221809B (fr) 1994-03-21
AU8189691A (en) 1991-12-31
KR930700102A (ko) 1993-03-13
JPH07116150B2 (ja) 1995-12-13
EP0593464A1 (fr) 1994-04-27
WO1991018601A1 (fr) 1991-12-12

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