ZA914322B - Pyridyl-benzoic acid derivatives for treating leukotrienerelated diseases - Google Patents

Pyridyl-benzoic acid derivatives for treating leukotrienerelated diseases

Info

Publication number
ZA914322B
ZA914322B ZA914322A ZA914322A ZA914322B ZA 914322 B ZA914322 B ZA 914322B ZA 914322 A ZA914322 A ZA 914322A ZA 914322 A ZA914322 A ZA 914322A ZA 914322 B ZA914322 B ZA 914322B
Authority
ZA
South Africa
Prior art keywords
leukotrienerelated
pyridyl
diseases
treating
benzoic acid
Prior art date
Application number
ZA914322A
Inventor
Robert A Daines
A Daines Robert
William Dennis Kingsbury
Dennis Kingsbury William
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of ZA914322B publication Critical patent/ZA914322B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA914322A 1990-06-07 1991-06-06 Pyridyl-benzoic acid derivatives for treating leukotrienerelated diseases ZA914322B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53439790A 1990-06-07 1990-06-07

Publications (1)

Publication Number Publication Date
ZA914322B true ZA914322B (en) 1992-06-24

Family

ID=24129867

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA914322A ZA914322B (en) 1990-06-07 1991-06-06 Pyridyl-benzoic acid derivatives for treating leukotrienerelated diseases

Country Status (17)

Country Link
EP (1) EP0593464A1 (en)
JP (1) JPH07116150B2 (en)
KR (1) KR930700102A (en)
CN (1) CN1058015A (en)
AU (1) AU655428B2 (en)
CA (1) CA2083957A1 (en)
FI (1) FI925545A (en)
HU (1) HUT64747A (en)
IL (1) IL98387A0 (en)
MA (1) MA22195A1 (en)
MX (1) MX26167A (en)
NZ (1) NZ238426A (en)
PL (1) PL290587A1 (en)
PT (1) PT97913A (en)
TW (1) TW221809B (en)
WO (1) WO1991018601A1 (en)
ZA (1) ZA914322B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0604529A1 (en) * 1991-09-19 1994-07-06 Smithkline Beecham Corporation Pyridine compounds for treating leukotriene-related diseases
IL106156A0 (en) * 1992-06-30 1993-10-20 Smithkline Beecham Corp Pyridinyl compounds
MX9303972A (en) * 1992-06-30 1994-04-29 Smithkline Beecham Corp PROCEDURE FOR MAKING THIOETER COMPOUNDS.
DE4224402A1 (en) * 1992-07-21 1994-01-27 Schering Ag New pyridine derivatives with leukotriene-B¶4¶ antagonistic effects
GR1001409B (en) * 1992-10-15 1993-11-30 Smithkline Beecham Corp Compounds for the treatment of diseases associated with leukotrienes.
ES2065234B1 (en) * 1992-10-27 1995-09-01 Smithkline Beecham Corp COMPOUNDS TO TREAT DISEASES RELATED TO LEUCOTRENEES.
US5643914A (en) * 1993-03-02 1997-07-01 Smithkline Beecham Corporation Pharmaceutical pyridine compounds
US5929096A (en) * 1996-02-29 1999-07-27 Smithkline Beecham Corporation Method for treating atopic dermatitis and contact dermatitis
CA2265996A1 (en) * 1996-09-26 1998-04-02 Roger Aki Fujimoto Aryl-substituted acrylamides with leukotriene b4 (ltb-4) receptor antagonist activity
EP3192872A1 (en) 2003-08-26 2017-07-19 The Regents of the University of Colorado, a body corporate Inhibitors of serine protease activity and their use in methods and compositions for treatment of bacterial infections
EP3812363B1 (en) * 2018-06-22 2022-08-03 Panasonic Holdings Corporation Organic salt, hydroxy-radical sensor including same, and detection medium

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4056619A (en) * 1975-09-08 1977-11-01 Warner-Lambert Company 1-Substituted-2-(2-pyridinyl)ethanone N-oxides

Also Published As

Publication number Publication date
TW221809B (en) 1994-03-21
JPH07116150B2 (en) 1995-12-13
FI925545A0 (en) 1992-12-07
KR930700102A (en) 1993-03-13
CN1058015A (en) 1992-01-22
HU9203867D0 (en) 1993-03-29
EP0593464A4 (en) 1993-02-12
AU655428B2 (en) 1994-12-22
MX26167A (en) 1994-02-28
PT97913A (en) 1992-03-31
IL98387A0 (en) 1992-07-15
HUT64747A (en) 1994-02-28
NZ238426A (en) 1994-11-25
AU8189691A (en) 1991-12-31
FI925545A (en) 1992-12-07
JPH05507492A (en) 1993-10-28
MA22195A1 (en) 1992-04-01
WO1991018601A1 (en) 1991-12-12
PL290587A1 (en) 1992-08-24
CA2083957A1 (en) 1991-12-08
EP0593464A1 (en) 1994-04-27

Similar Documents

Publication Publication Date Title
HU907339D0 (en) Process for treating diseases
IL103126A0 (en) 5-amino-4-hydroxyhexanoic acid derivatives as therapeutic agents
ZA914001B (en) Essential fatty acid treatment
HU9501923D0 (en) Substituted azolone derivatives for treating diseases caused by helicobacter
IL103205A0 (en) Compounds for treating leukotriene-related diseases
ZA93190B (en) Benzofuranyl- and thiophenylmethylthio-alkanecarboxylic acid derivatives
ZA914322B (en) Pyridyl-benzoic acid derivatives for treating leukotrienerelated diseases
IL98388A0 (en) Benzoic acid derivatives for treating leukotriene-related diseases
ZA914369B (en) Amide linked pyridyl-benzoic acid derivatives for treating leukotriene-related diseases
EP0444156A4 (en) Method for treating vascular diseases
EP0421752A3 (en) Substituted acrylamido-penicillanic acid derivatives
CS22891A2 (en) Application of benzylphosphonic acid's derivatives for treatment of virusinduced diseases
ZA931367B (en) Sulphonylbenzyl-substituted imidazolylpropenoic acid derivatives
IL97210A0 (en) Process for the preparation of 7-amino-3-methoxymethyl-ceph-3-em-carboxylic acid
ZA93125B (en) Quinolone- and naphthyridone-carboxylic acid derivatives
NO924701D0 (en) AMID-BONDED PYRIDYL-BENZOIC ACID DERIVATIVES FOR TREATING AVLEUCOTRIEN-RELATED DISEASES
HU905999D0 (en) Process for the preparation of rodanido-isobutyric acid
HUT57734A (en) Process for producing pyrazaolecarboxylic acid derivatives
ZA903999B (en) Mevinic acid derivatives
GB8809871D0 (en) -amino-alkanoic acid derivative & processes
NO924702D0 (en) PYRIDYL-BENZO ACID DERIVATIVES FOR TREATING LEUKOTRIEN-RELATED DISEASES
EP0446925A3 (en) Process for the preparation of beta-resorcylic acid derivatives
ZA926938B (en) Further novel 5-amino-4-hydroxyhexanoic acid derivatives as therapeutic agents
IE901047L (en) Thienylacetic acid derivatives
IE901971L (en) Mevinic acid derivatives