ZA914322B - Pyridyl-benzoic acid derivatives for treating leukotrienerelated diseases - Google Patents

Pyridyl-benzoic acid derivatives for treating leukotrienerelated diseases

Info

Publication number
ZA914322B
ZA914322B ZA914322A ZA914322A ZA914322B ZA 914322 B ZA914322 B ZA 914322B ZA 914322 A ZA914322 A ZA 914322A ZA 914322 A ZA914322 A ZA 914322A ZA 914322 B ZA914322 B ZA 914322B
Authority
ZA
South Africa
Prior art keywords
leukotrienerelated
pyridyl
diseases
treating
benzoic acid
Prior art date
Application number
ZA914322A
Other languages
English (en)
Inventor
Robert A Daines
A Daines Robert
William Dennis Kingsbury
Dennis Kingsbury William
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of ZA914322B publication Critical patent/ZA914322B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/65One oxygen atom attached in position 3 or 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA914322A 1990-06-07 1991-06-06 Pyridyl-benzoic acid derivatives for treating leukotrienerelated diseases ZA914322B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53439790A 1990-06-07 1990-06-07

Publications (1)

Publication Number Publication Date
ZA914322B true ZA914322B (en) 1992-06-24

Family

ID=24129867

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA914322A ZA914322B (en) 1990-06-07 1991-06-06 Pyridyl-benzoic acid derivatives for treating leukotrienerelated diseases

Country Status (17)

Country Link
EP (1) EP0593464A1 (xx)
JP (1) JPH07116150B2 (xx)
KR (1) KR930700102A (xx)
CN (1) CN1058015A (xx)
AU (1) AU655428B2 (xx)
CA (1) CA2083957A1 (xx)
FI (1) FI925545A0 (xx)
HU (1) HUT64747A (xx)
IL (1) IL98387A0 (xx)
MA (1) MA22195A1 (xx)
MX (1) MX26167A (xx)
NZ (1) NZ238426A (xx)
PL (1) PL290587A1 (xx)
PT (1) PT97913A (xx)
TW (1) TW221809B (xx)
WO (1) WO1991018601A1 (xx)
ZA (1) ZA914322B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2119467A1 (en) * 1991-09-19 1993-04-01 Pamela Anne Chambers Pyridine compounds for treating leukotriene-related diseases
AU678979B2 (en) * 1992-06-30 1997-06-19 Smithkline Beecham Corporation Process for making phenylthiomethylpyridinylalkenoates
MA22926A1 (fr) * 1992-06-30 1994-04-01 Smithkline Beecham Corp Procede pour la preparation de nouveaux composes.
DE4224402A1 (de) * 1992-07-21 1994-01-27 Schering Ag Neue Pyridin-Derivate mit Leukotrien-B¶4¶-antagonistischer Wirkung
GR1001409B (el) * 1992-10-15 1993-11-30 Smithkline Beecham Corp Ενώσεις για την ?εραπευτική αγωγή ασ?ενειών που έχουν σχέση με λευκοτριένια.
ES2065234B1 (es) * 1992-10-27 1995-09-01 Smithkline Beecham Corp Compuestos para tratar enfermedades relacionadas con los leucotrienos.
US5643914A (en) * 1993-03-02 1997-07-01 Smithkline Beecham Corporation Pharmaceutical pyridine compounds
US5929096A (en) * 1996-02-29 1999-07-27 Smithkline Beecham Corporation Method for treating atopic dermatitis and contact dermatitis
JP2001501202A (ja) * 1996-09-26 2001-01-30 ノバルティス アクチエンゲゼルシャフト ロイコトリエンb4(ltb―4)レセプターアンタゴニスト活性によるアリル置換アクリルアミド
EP3192872A1 (en) 2003-08-26 2017-07-19 The Regents of the University of Colorado, a body corporate Inhibitors of serine protease activity and their use in methods and compositions for treatment of bacterial infections
JP7339945B2 (ja) * 2018-06-22 2023-09-06 パナソニックホールディングス株式会社 有機塩とこれを備えるヒドロキシラジカルセンサ及び検出メディア

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4056619A (en) * 1975-09-08 1977-11-01 Warner-Lambert Company 1-Substituted-2-(2-pyridinyl)ethanone N-oxides

Also Published As

Publication number Publication date
TW221809B (xx) 1994-03-21
FI925545A (fi) 1992-12-07
KR930700102A (ko) 1993-03-13
HU9203867D0 (en) 1993-03-29
AU8189691A (en) 1991-12-31
HUT64747A (en) 1994-02-28
AU655428B2 (en) 1994-12-22
NZ238426A (en) 1994-11-25
MX26167A (es) 1994-02-28
MA22195A1 (fr) 1992-04-01
PL290587A1 (en) 1992-08-24
EP0593464A4 (en) 1993-02-12
JPH05507492A (ja) 1993-10-28
CN1058015A (zh) 1992-01-22
IL98387A0 (en) 1992-07-15
EP0593464A1 (en) 1994-04-27
CA2083957A1 (en) 1991-12-08
PT97913A (pt) 1992-03-31
WO1991018601A1 (en) 1991-12-12
JPH07116150B2 (ja) 1995-12-13
FI925545A0 (fi) 1992-12-07

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