NZ222401A - Pharmaceutical compositions which include a calcium antagonist and 7-(n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-(s)-alanyl)-1,4-dithia-7-azaspiro(4,4)nonane-8-(s)-carboxylic acid - Google Patents

Pharmaceutical compositions which include a calcium antagonist and 7-(n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-(s)-alanyl)-1,4-dithia-7-azaspiro(4,4)nonane-8-(s)-carboxylic acid

Info

Publication number
NZ222401A
NZ222401A NZ222401A NZ22240187A NZ222401A NZ 222401 A NZ222401 A NZ 222401A NZ 222401 A NZ222401 A NZ 222401A NZ 22240187 A NZ22240187 A NZ 22240187A NZ 222401 A NZ222401 A NZ 222401A
Authority
NZ
New Zealand
Prior art keywords
alkyl
carbon atoms
composition according
dimethyl
hydroxy
Prior art date
Application number
NZ222401A
Other languages
English (en)
Inventor
Helen Siegl
Robert Paul Hof
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868626217A external-priority patent/GB8626217D0/en
Priority claimed from GB878713349A external-priority patent/GB8713349D0/en
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of NZ222401A publication Critical patent/NZ222401A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NZ222401A 1986-11-03 1987-11-02 Pharmaceutical compositions which include a calcium antagonist and 7-(n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-(s)-alanyl)-1,4-dithia-7-azaspiro(4,4)nonane-8-(s)-carboxylic acid NZ222401A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868626217A GB8626217D0 (en) 1986-11-03 1986-11-03 Pharmaceutical compositions
GB878713349A GB8713349D0 (en) 1987-06-08 1987-06-08 Pharmaceutical compositions

Publications (1)

Publication Number Publication Date
NZ222401A true NZ222401A (en) 1991-04-26

Family

ID=26291485

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ222401A NZ222401A (en) 1986-11-03 1987-11-02 Pharmaceutical compositions which include a calcium antagonist and 7-(n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-(s)-alanyl)-1,4-dithia-7-azaspiro(4,4)nonane-8-(s)-carboxylic acid

Country Status (25)

Country Link
KR (1) KR960005145B1 (cs)
AT (1) AT397343B (cs)
AU (1) AU615883B2 (cs)
BE (1) BE1002063A4 (cs)
CA (1) CA1314222C (cs)
CH (1) CH677189A5 (cs)
DE (1) DE3736505A1 (cs)
DK (1) DK574087A (cs)
ES (1) ES2010524A6 (cs)
FI (1) FI874823L (cs)
FR (1) FR2605885B1 (cs)
GR (1) GR871680B (cs)
HK (1) HK138893A (cs)
HU (1) HU199681B (cs)
IE (1) IE60496B1 (cs)
IL (1) IL84343A (cs)
IT (1) IT1212037B (cs)
LU (1) LU87034A1 (cs)
MY (1) MY102124A (cs)
NL (1) NL8702502A (cs)
NO (1) NO874539L (cs)
NZ (1) NZ222401A (cs)
PH (1) PH23249A (cs)
PT (1) PT86062B (cs)
SE (1) SE8704272L (cs)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3818245A1 (de) * 1988-05-28 1989-12-07 Hoechst Ag Kombination von angiotensin-converting-enzyme-hemmern mit kaliumkanal-modulatoren sowie deren verwendung in arzneimitteln
FR2733911B1 (fr) * 1995-05-09 1998-05-29 Takeda Chemical Industries Ltd Composition pharmaceutique pour maladies renales ou cardio-vasculaires

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4470972A (en) * 1981-04-28 1984-09-11 Schering Corporation 7-Carboxyalkylaminoacyl-1,4-dithia-7-azaspiro[4.4]-nonane-8-carboxylic acids
US4520021A (en) * 1982-07-02 1985-05-28 Merck & Co., Inc. Substituted caprolactam derivatives as antihypertensives
DE3437917A1 (de) * 1984-10-17 1986-04-17 Bayer Ag, 5090 Leverkusen Kombination von dihydropyridinen mit ace-hemmern sowie ihre verwendung in arzneimitteln
DE3633496A1 (de) * 1986-10-02 1988-04-14 Hoechst Ag Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln
GB2198641B (en) * 1986-11-03 1990-09-19 Sandoz Ltd Pharmaceutical composition for use against hypertension and congestive heart failure
IL88502A (en) * 1987-12-14 1993-04-04 Squibb & Sons Inc Pharmaceutical compositions containing an angiotensin converting enzyme inhibitor

Also Published As

Publication number Publication date
SE8704272L (sv) 1988-05-04
GR871680B (en) 1988-05-02
SE8704272D0 (sv) 1987-11-02
DK574087D0 (da) 1987-11-02
FR2605885A1 (fr) 1988-05-06
CA1314222C (en) 1993-03-09
HU199681B (en) 1990-03-28
HUT47847A (en) 1989-04-28
HK138893A (en) 1993-12-24
PT86062A (en) 1987-12-01
IL84343A (en) 1993-07-08
FI874823A7 (fi) 1988-05-04
ATA286987A (de) 1993-08-15
AU615883B2 (en) 1991-10-17
CH677189A5 (cs) 1991-04-30
AT397343B (de) 1994-03-25
DK574087A (da) 1988-05-04
FR2605885B1 (fr) 1993-09-10
IE872951L (en) 1988-05-03
KR880006197A (ko) 1988-07-22
AU8057687A (en) 1988-05-05
PT86062B (pt) 1990-11-07
BE1002063A4 (fr) 1990-06-12
IT8748553A0 (it) 1987-10-30
FI874823A0 (fi) 1987-11-02
NL8702502A (nl) 1988-06-01
PH23249A (en) 1989-06-16
KR960005145B1 (ko) 1996-04-22
LU87034A1 (fr) 1988-05-03
ES2010524A6 (es) 1989-11-16
MY102124A (en) 1992-03-31
DE3736505A1 (de) 1988-05-05
IT1212037B (it) 1989-11-08
NO874539D0 (no) 1987-11-02
NO874539L (no) 1988-05-04
IL84343A0 (en) 1990-02-09
IE60496B1 (en) 1994-07-27
FI874823L (fi) 1988-05-04

Similar Documents

Publication Publication Date Title
US6248729B1 (en) Combination of an ADP-receptor blocking antiplatelet drug and antihypertensive drug and a method for preventing a cerebral infarction employing such combination
US5026716A (en) Method of treatment of anxiety and anxio-depressive disorders
PH26920A (en) Medicaments for the treatment of cerebral apoplexy
JP2002537258A5 (cs)
US5093129A (en) Method for treating addiction to a drug of abuse employing an ace inhibitor
US4859665A (en) Antihypertensive combination products containing a dihydropyridine and a pyridazodiazepine
JPH0334926A (ja) 抗不安薬
NZ222401A (en) Pharmaceutical compositions which include a calcium antagonist and 7-(n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-(s)-alanyl)-1,4-dithia-7-azaspiro(4,4)nonane-8-(s)-carboxylic acid
US4871738A (en) Use of 2-pyrimidinyl-1-piperazine derivatives in the treatment of dependence on nicotine
US4157394A (en) Cardio-protective pharmaceutical composition
US4797404A (en) Pharmaceutical preparation comprising co-dergocrine and a calcium antagonist
RO117297B1 (ro) Metoda de tratament a alcoolismului cronic sau a starilor datorate abuzului de alcool
CY1702A (en) Pharmaceutical composition for use against hypertension and congestive heart failure
GB2198641A (en) Pharmaceutical cardiac compositions containing calcium antagonists
EP0381074A2 (en) Method for facilitating dieting employing an ACE inhibitor
US4259346A (en) Bradycardiac pharmaceutical compositions and method of use
NL194958C (nl) Farmaceutische eenheidsdosering van benazepril/thiazidediureticum in lage dosering.
USH734H (en) Method for inhibiting onset of or treating migraine headaches employing an ACE inhibitor
EP1179345B1 (en) Inhibitors against increase in ocular tension caused by irradiation with lasers, containing 1,4-dihydropyridine derivatives
EP0334264A2 (en) Pharmaceutical compositions for treating tardive dyskinesia employing an ace inhibitor
JPS63132835A (ja) 高血圧およびうっ血性心不全用医薬組成物
US5030648A (en) Combination and method for treating obsessive-compulsive disorder, and motor and phonic tics in Tourettes' syndrome using such combination
JPS60202818A (ja) 抗潰瘍剤