NZ212937A - Omega interferons: production by recombinant dna processes; pharmaceutical compositions - Google Patents

Omega interferons: production by recombinant dna processes; pharmaceutical compositions

Info

Publication number
NZ212937A
NZ212937A NZ212937A NZ21293785A NZ212937A NZ 212937 A NZ212937 A NZ 212937A NZ 212937 A NZ212937 A NZ 212937A NZ 21293785 A NZ21293785 A NZ 21293785A NZ 212937 A NZ212937 A NZ 212937A
Authority
NZ
New Zealand
Prior art keywords
production
pharmaceutical compositions
recombinant dna
dna processes
interferons
Prior art date
Application number
NZ212937A
Other languages
English (en)
Inventor
Rudolf Hauptmann
Peter Meindl
Eva Rastl-Dworkin
Gunther Adolf
Peter Swetly
Christian Pieler
Norbert Hauel
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE3428370A external-priority patent/DE3428370A1/de
Priority claimed from DE19853505060 external-priority patent/DE3505060A1/de
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of NZ212937A publication Critical patent/NZ212937A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Electrotherapy Devices (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
NZ212937A 1984-08-01 1985-07-31 Omega interferons: production by recombinant dna processes; pharmaceutical compositions NZ212937A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3428370A DE3428370A1 (de) 1984-08-01 1984-08-01 Interferon, genetische sequenzen, die hierfuer codieren, und diese produzierende organismen
DE19853505060 DE3505060A1 (de) 1985-02-14 1985-02-14 Neue interferone vom typ i, genetische sequenzen, die hierfuer codieren, und diese produzierende organismen

Publications (1)

Publication Number Publication Date
NZ212937A true NZ212937A (en) 1991-08-27

Family

ID=25823496

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ212937A NZ212937A (en) 1984-08-01 1985-07-31 Omega interferons: production by recombinant dna processes; pharmaceutical compositions

Country Status (21)

Country Link
EP (1) EP0170204B1 (enExample)
JP (2) JP2566909B2 (enExample)
KR (1) KR0136799B1 (enExample)
AT (1) ATE67786T1 (enExample)
AU (1) AU600653B2 (enExample)
BG (1) BG60445B2 (enExample)
CA (1) CA1340184C (enExample)
DD (1) DD246318A5 (enExample)
DE (1) DE3584198D1 (enExample)
DK (1) DK175194B1 (enExample)
ES (2) ES8609475A1 (enExample)
FI (1) FI90667C (enExample)
GR (1) GR851866B (enExample)
HK (1) HK187896A (enExample)
HU (1) HU205779B (enExample)
IE (1) IE58942B1 (enExample)
IL (1) IL75963A (enExample)
MX (1) MX9203645A (enExample)
NO (1) NO177863C (enExample)
NZ (1) NZ212937A (enExample)
PT (1) PT80901B (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231176A (en) * 1984-08-27 1993-07-27 Genentech, Inc. Distinct family DNA encoding of human leukocyte interferons
DE3607835A1 (de) * 1986-03-10 1987-09-24 Boehringer Ingelheim Int Hybridinterferone, deren verwendung als arzneimittel und als zwischenprodukte zur herstellung von antikoerpern und deren verwendung sowie verfahren zu ihrer herstellung
EP0490233A1 (de) * 1986-03-10 1992-06-17 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Monoclonale Antikörper gegen BgIII-Hybridinterferone, deren Verwendung und Verfahren zu ihrer Herstellung
US4863727A (en) * 1986-04-09 1989-09-05 Cetus Corporation Combination therapy using interleukin-2 and tumor necrosis factor
DE3633323A1 (de) * 1986-10-01 1988-04-07 Boehringer Ingelheim Int Neue monoklonale antikoerper gegen ifn-omega, verfahren zu ihrer herstellung und deren verwendung zur reinigung sowie zum nachweis von ifn-omega
DE3635867A1 (de) * 1986-10-22 1988-05-11 Boehringer Ingelheim Int Neue hefeexpressionsvektoren fuer ifn-omega, verfahren zu ihrer herstellung und deren verwendung
JP2001523480A (ja) 1997-11-20 2001-11-27 バイカル インコーポレイテッド サイトカイン発現ポリヌクレオチドおよびそれらの組成物を用いた癌の処置
WO2000040273A2 (en) * 1999-01-08 2000-07-13 Vical Incorporated Treatment of viral diseases using an interferon omega expressing polynucleotide
DK1481057T3 (da) 2002-03-07 2006-05-15 Eidgenoess Tech Hochschule System og fremgangsmåde til fremstilling af rekombinante glycosylerede proteiner i en prokaryot vært
JP4727927B2 (ja) * 2002-03-07 2011-07-20 アイトゲネシシェ・テッヒニシェ・ホーホシューレ・チューリッヒ 原核宿主における組換えグリコシル化タンパク質産生のためのシステムおよび方法
CA2522345A1 (en) 2003-04-09 2004-11-18 Neose Technologies, Inc. Glycopegylation methods and proteins/peptides produced by the methods
WO2004096852A1 (fr) * 2003-04-25 2004-11-11 The Institute Of Microbiology And Epidemiology, Academy Of Military Medical Sciemces, Pla Interferon$g(v) humain recombinant, son procede d'expression et ses utilisations
ES2535084T3 (es) 2005-05-11 2015-05-05 Eth Zurich Proteínas N-glicosiladas recombinantes procedentes de células procariotas
SI2257307T1 (sl) 2008-02-20 2018-09-28 Glaxosmithkline Biologicals S.A. Biokonjugati, izdelani iz rekombinantnih N-glikoziliranih proteinov iz prokariontskih celic
NO2501406T3 (enExample) 2009-11-19 2018-05-19
WO2011138361A1 (en) 2010-05-06 2011-11-10 Glycovaxyn Capsular gram-positive bacteria bioconjugate vaccines
WO2013024156A2 (en) 2011-08-17 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations of anti-hcv-entry factor antibodies and interferons for the treatment and the prevention of hcv infection
WO2013024158A1 (en) 2011-08-17 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations of protein kinase inhibitors and interferons or of protein kinase inhibitors and direct acting antivirals for the treatment and the prevention of hcv infection
WO2014033266A1 (en) 2012-08-31 2014-03-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Anti-sr-bi antibodies for the inhibition of hepatitis c virus infection

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1217440A (en) * 1982-08-18 1987-02-03 Michael A. Innis INTERFERON .alpha. 6L
AU1946283A (en) * 1982-08-18 1984-03-07 Cetus Corporation Interferon-alpha 6l
DE3247922A1 (de) * 1982-12-24 1984-06-28 Boehringer Ingelheim International GmbH, 6507 Ingelheim Dna-sequenzen, deren herstellung, diese sequenzen enthaltende plasmide und deren verwendung zur synthese eukaryotischer genprodukte in prokaryoten
DE3574145D1 (en) * 1984-08-27 1989-12-14 Genentech Inc Novel, distinct family of human leukocyte interferons, compositions containing them, methods for their production, and dna and transfected hosts therefor

Also Published As

Publication number Publication date
PT80901A (de) 1985-09-01
HUT39477A (en) 1986-09-29
FI852956L (fi) 1986-02-02
ES545725A0 (es) 1986-08-01
DE3584198D1 (de) 1991-10-31
FI852956A0 (fi) 1985-07-31
CA1340184C (en) 1998-12-15
GR851866B (enExample) 1985-12-02
ES8708013A1 (es) 1987-09-01
JP2566909B2 (ja) 1996-12-25
IL75963A (en) 1992-05-25
KR0136799B1 (ko) 1998-04-25
ES8609475A1 (es) 1986-08-01
ES552431A0 (es) 1987-09-01
HK187896A (en) 1996-10-18
IL75963A0 (en) 1985-12-31
JPS61181381A (ja) 1986-08-14
EP0170204B1 (de) 1991-09-25
DK346385D0 (da) 1985-07-30
IE851906L (en) 1986-02-01
NO853012L (no) 1986-02-03
FI90667C (fi) 1994-03-10
ATE67786T1 (de) 1991-10-15
MX9203645A (es) 1992-09-01
NO177863B (no) 1995-08-28
KR870001310A (ko) 1987-03-13
JP2567195B2 (ja) 1996-12-25
EP0170204A2 (de) 1986-02-05
HU205779B (en) 1992-06-29
DK175194B1 (da) 2004-07-05
NO177863C (no) 1995-12-06
AU600653B2 (en) 1990-08-23
FI90667B (fi) 1993-11-30
JPH06181771A (ja) 1994-07-05
PT80901B (pt) 1989-01-17
IE58942B1 (en) 1993-12-01
DD246318A5 (de) 1987-06-03
AU4554985A (en) 1986-02-06
DK346385A (da) 1986-02-02
BG60445B2 (bg) 1995-03-31
EP0170204A3 (en) 1988-02-17

Similar Documents

Publication Publication Date Title
AU553400B2 (en) Recombinant dna for producing interferon
IE851906L (en) Interferons
IL64243A (en) Hybrid human leukocyte interferon type anti-viral polypeptides,their preparation by genetic engineering methods and pharmaceutical compositions containing them
ES8403969A1 (es) Un metodo para producir polipetido semejante a interferon inmune humano.
IL77369A (en) Alpha, beta or omega horse interferon, their preparation and pharmaceutical compositions containing them, recombinant dna coding therefor and transformed host organisms containing such dna
IT8119760A0 (it) Polipeptide prodotto microbiologicamente con la sequenza di aminoacidi dell'interferone umano, dna e plasmidi che codificano per questa sequenza, microorganismi che contengono queste informazioni genetiche e processo per la loro preparazione.
ES8601237A1 (es) Procedimiento para preparar dnas y dnas recombinantes
HUT46061A (en) Dna sequences encoding hirudin-like protein and process for producing such proteins
ATE501254T1 (de) P- selectin ligandenprotein
IL70856A0 (en) Dna sequences,recombinant dna molecules and processes for producing human interleukin two-like polypeptides
EP0088622A3 (en) Animal interferons, processes involved in their production, compositions containing them, dna sequences coding therefor and expression vehicles containing such sequences and cells transformed thereby
IL80562A0 (en) Recombinant human lysozyme,its preparation by recombinant dna technology and pharmaceutical compositions containing it
DE3850774D1 (de) Rinder-interleukin-1-alpha.
EP0183272A3 (en) Vector capable of efficient gene expression and utilization of such vector
SG134394G (en) Genetic sequences, type I interferon peptide coded by them, and these organisms producing the same
ZA84512B (en) Dna sequences,recombinant dna molecules and processes for producing human interleukin two-like polypeptides
ZA812189B (en) Dna sequences, recombinant dna molecules and processes for producing human fibroblast interferon-like polypeptides