NZ200526A - 1,2,3,4-tetrahydro-2-naphthylamine derivatives - Google Patents

1,2,3,4-tetrahydro-2-naphthylamine derivatives

Info

Publication number
NZ200526A
NZ200526A NZ200526A NZ20052682A NZ200526A NZ 200526 A NZ200526 A NZ 200526A NZ 200526 A NZ200526 A NZ 200526A NZ 20052682 A NZ20052682 A NZ 20052682A NZ 200526 A NZ200526 A NZ 200526A
Authority
NZ
New Zealand
Prior art keywords
group
carbon atoms
compound
alkyl
formula
Prior art date
Application number
NZ200526A
Other languages
English (en)
Inventor
F L-E Arvidsson
P A E Carlsson
U A Hacksell
J S M Hjort
A M Johansson
P L Lindberg
J L G Nilsson
D Sanchez
H V Wikstrom
Original Assignee
Astra Laekemedel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab
Publication of NZ200526A publication Critical patent/NZ200526A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
NZ200526A 1981-05-08 1982-05-05 1,2,3,4-tetrahydro-2-naphthylamine derivatives NZ200526A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8102908 1981-05-08

Publications (1)

Publication Number Publication Date
NZ200526A true NZ200526A (en) 1985-09-13

Family

ID=20343779

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ200526A NZ200526A (en) 1981-05-08 1982-05-05 1,2,3,4-tetrahydro-2-naphthylamine derivatives

Country Status (16)

Country Link
US (1) US4876284A (enExample)
EP (1) EP0064964B1 (enExample)
JP (1) JPS57192344A (enExample)
AT (1) ATE8874T1 (enExample)
AU (2) AU554206B2 (enExample)
CA (1) CA1236113A (enExample)
DE (1) DE3260529D1 (enExample)
DK (1) DK164937C (enExample)
ES (4) ES8306708A1 (enExample)
FI (1) FI78067C (enExample)
GR (1) GR77121B (enExample)
IE (1) IE53143B1 (enExample)
IL (1) IL65501A (enExample)
NO (1) NO152902C (enExample)
NZ (1) NZ200526A (enExample)
PH (2) PH18065A (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL65501A (en) * 1981-05-08 1986-04-29 Astra Laekemedel Ab 1-alkyl-2-aminotetralin derivatives,process for their preparation and pharmaceutical compositions containing them
US4743618A (en) * 1983-01-03 1988-05-10 Nelson Research & Development Co. Substituted 2-aminotetralins
US4657925A (en) * 1984-08-13 1987-04-14 Nelson Research & Development Co. Method and compositions for reducing the intraocular pressure of mammals
US4722933A (en) * 1985-12-20 1988-02-02 Nelson Research & Development Co. Substituted 2-aminotetralins
GB2157950B (en) * 1984-05-04 1988-11-02 Nelson Res & Dev Selective d-2 dopamine receptor agonist
AU573828B2 (en) * 1984-05-17 1988-06-23 E.R. Squibb & Sons, Inc. Tetrahydronaphthalenols
DE3479314D1 (en) * 1984-05-22 1989-09-14 Nelson Res & Dev Substituted 2-aminotetralins and processes for synthesis
DE3718317A1 (de) * 1986-12-10 1988-06-16 Bayer Ag Substituierte basische 2-aminotetraline
US5091526A (en) * 1988-07-29 1992-02-25 Schering Corporation Process for the enantiospecific synthesis of intermediates for hexahydro-benzo[d]-naphtho[2,1-b]azepines
JPH03505735A (ja) * 1988-07-29 1991-12-12 シェリング・コーポレーション ヘキサヒドロ―ベンゾ［ｄ］―ナフト［２，１―ｂ］アゼピンのための中間体の対掌体特異的合成のための方法
CA1335106C (en) * 1989-02-27 1995-04-04 John Mehnert Schaus Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes
SE8901889D0 (sv) * 1989-05-26 1989-05-26 Astra Ab Novel 8-substituted-2-aminotetralines
DE69032725T2 (de) * 1989-05-31 1999-04-08 Pharmacia & Upjohn Co., Kalamazoo, Mich. ZNS-wirksame 8-Heterocyclyl-2-aminotetralin Derivate
IT1232160B (it) * 1989-07-31 1992-01-25 Sigma Tau Ind Farmaceuti 2-(n-acil)ammino-6,7-dimetossi tetraline, procedimento per la loro preparazione e composizioni farmaceutiche ad attivita' antiipertensiva che le contengono
WO1991009594A1 (en) * 1989-12-28 1991-07-11 Virginia Commonwealth University Sigma receptor ligands and the use thereof
DE69124868T2 (de) * 1990-08-15 1997-07-10 Lilly Co Eli Ring-substituierte 2-Amino-1,2,3,4-tetra-hydronaphthaline, 3-Aminochromane und 3-Aminothiochromane
WO1992019234A2 (en) * 1991-04-26 1992-11-12 The Upjohn Company Method of treating/preventing substance abuse using 1-alkyl-5(substituted oxy)-2-aminotetralins
AU676993B2 (en) * 1991-06-27 1997-04-10 Virginia Commonwealth University Sigma receptor ligands and the use thereof
IT1251877B (it) * 1991-09-26 1995-05-26 Zambon Spa Processo per la preparazione di 2-ammino-5,6 dimetossi-tetralina
WO1994022495A1 (en) * 1993-03-31 1994-10-13 The Trustees Of The University Of Pennsylvania Dopamine d-3 and serotonin (5-ht1a) receptor ligands and imaging agents
US6087346A (en) * 1993-06-23 2000-07-11 Cambridge Neuroscience, Inc. Sigma receptor ligands and the use thereof
GB9315566D0 (en) * 1993-07-28 1993-09-08 Smithkline Beecham Plc Medicaments
US6008219A (en) * 1995-03-27 1999-12-28 Smithkline Beech P.L.C. Bicyclic amine derivatives and their use as anti-psychotic agents
US5646188A (en) * 1995-07-05 1997-07-08 Teva Pharmaceutical Industries, Ltd. Polyamine derivatives of 1-aminoindan
CA2346363A1 (en) * 1998-10-07 2000-04-13 Ortho-Mcneil Pharmaceutical, Inc. N-aralkylaminotetralins as ligands for the neuropeptide y y5 receptor
ATE533743T1 (de) 2002-05-17 2011-12-15 Janssen Pharmaceutica Nv Harnstoffderivate von aminotetralin als modulatoren des vanilloid-rezeptors vr1
EP2098511A1 (en) 2008-03-07 2009-09-09 Solvias AG Process for preparing compounds containing a hydronaphtalene structure with an unsymmetrically substituted benzene ring
DE102010020553A1 (de) 2010-05-14 2011-11-17 Bayer Schering Pharma Aktiengesellschaft Substituierte 8-Alkoxy-2-aminotetralin-Derivate und ihre Verwendung
ES2616036T3 (es) 2012-07-20 2017-06-09 Bayer Pharma Aktiengesellschaft Nuevos ácidos 5-aminotetrahidroquinolin-2-carboxílicos y su uso
ES2603262T3 (es) 2012-07-20 2017-02-24 Bayer Pharma Aktiengesellschaft Ácidos aminoindano-carboxílicos y aminotetralin-carboxílicos sustituidos y su uso
IL313922A (en) 2021-12-29 2024-08-01 Bayer Ag Process for preparing (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4'-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]amino} 8,7,6,5-tetrahydroquinoline-2-carboxylic acid and crystalline forms thereof for use as a pharmaceutical active compound
KR20240144178A (ko) 2021-12-29 2024-10-02 바이엘 악티엔게젤샤프트 심폐 장애의 치료

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1017359A (en) * 1972-07-03 1977-09-13 Frederic P. Hauck Substituted cyclic polymethylene phenols
JPS5124508B2 (enExample) * 1972-08-14 1976-07-24
DE2752659A1 (de) * 1976-12-07 1978-06-08 Sandoz Ag Neue tetralinderivate, ihre herstellung und verwendung
DE3062971D1 (en) * 1979-09-14 1983-06-09 Sandoz Ag Derivatives of tetraline, their preparation and medicaments containing these compounds
AU7179781A (en) * 1980-05-29 1981-12-21 Astra Lakemedel Aktiebolag Therapeutically useful tetralin derivatives
IL65501A (en) * 1981-05-08 1986-04-29 Astra Laekemedel Ab 1-alkyl-2-aminotetralin derivatives,process for their preparation and pharmaceutical compositions containing them
FR2512814A1 (fr) * 1981-09-16 1983-03-18 Synthelabo Derives d'amino-2 tetrahydro-1,2,3,4 naphtalene, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
ES511986A0 (es) 1983-06-01
DK164937B (da) 1992-09-14
JPH0419221B2 (enExample) 1992-03-30
FI78067B (fi) 1989-02-28
FI821598L (fi) 1982-11-09
IE821076L (en) 1982-11-08
ATE8874T1 (de) 1984-08-15
AU554206B2 (en) 1986-08-14
CA1236113A (en) 1988-05-03
NO152902C (no) 1985-12-11
PH19585A (en) 1986-05-26
IE53143B1 (en) 1988-07-20
ES8506591A1 (es) 1985-08-01
FI821598A0 (fi) 1982-05-06
NO821494L (no) 1982-11-09
NO152902B (no) 1985-09-02
AU572497B2 (en) 1988-05-12
FI78067C (fi) 1989-06-12
ES519615A0 (es) 1985-05-01
DK164937C (da) 1993-02-01
ES535882A0 (es) 1985-12-01
AU2587984A (en) 1984-06-28
DE3260529D1 (en) 1984-09-13
ES8306708A1 (es) 1983-06-01
EP0064964B1 (en) 1984-08-08
ES529311A0 (es) 1985-08-01
ES8602603A1 (es) 1985-12-01
US4876284A (en) 1989-10-24
GR77121B (enExample) 1984-09-07
IL65501A0 (en) 1982-07-30
PH18065A (en) 1985-03-18
ES8504666A1 (es) 1985-05-01
EP0064964A1 (en) 1982-11-17
DK202882A (da) 1982-11-09
IL65501A (en) 1986-04-29
AU8340982A (en) 1982-11-11
JPS57192344A (en) 1982-11-26

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