ES535882A0 - Un procedimiento para la preparacion de nuevas 1,2,3,4-tetrahidro-2-naftilaminas - Google Patents

Un procedimiento para la preparacion de nuevas 1,2,3,4-tetrahidro-2-naftilaminas

Info

Publication number
ES535882A0
ES535882A0 ES535882A ES535882A ES535882A0 ES 535882 A0 ES535882 A0 ES 535882A0 ES 535882 A ES535882 A ES 535882A ES 535882 A ES535882 A ES 535882A ES 535882 A0 ES535882 A0 ES 535882A0
Authority
ES
Spain
Prior art keywords
carbon atoms
group
alkyl group
compounds
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES535882A
Other languages
English (en)
Other versions
ES8602603A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astra Lakemedel AB
Original Assignee
Astra Lakemedel AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Lakemedel AB filed Critical Astra Lakemedel AB
Publication of ES535882A0 publication Critical patent/ES535882A0/es
Publication of ES8602603A1 publication Critical patent/ES8602603A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
ES535882A 1981-05-08 1984-09-13 Un procedimiento para la preparacion de nuevas 1,2,3,4-tetrahidro-2-naftilaminas Expired ES8602603A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8102908 1981-05-08

Publications (2)

Publication Number Publication Date
ES535882A0 true ES535882A0 (es) 1985-12-01
ES8602603A1 ES8602603A1 (es) 1985-12-01

Family

ID=20343779

Family Applications (4)

Application Number Title Priority Date Filing Date
ES511986A Expired ES8306708A1 (es) 1981-05-08 1982-05-07 "un procedimiento para la preparacion de nuevas 1,2,3,4 tetrahidro 2 naftilaminas".
ES519615A Expired ES8504666A1 (es) 1981-05-08 1983-02-08 Un procedimiento para la preparacion de nuevas 1,2,3,4-tetrahidro-2-naftilaminas.
ES529311A Granted ES529311A0 (es) 1981-05-08 1984-01-31 Un procedimiento para la preparacion de nuevas 1,2,3,4--tetrahidro-2-naftilaminas.
ES535882A Expired ES8602603A1 (es) 1981-05-08 1984-09-13 Un procedimiento para la preparacion de nuevas 1,2,3,4-tetrahidro-2-naftilaminas

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES511986A Expired ES8306708A1 (es) 1981-05-08 1982-05-07 "un procedimiento para la preparacion de nuevas 1,2,3,4 tetrahidro 2 naftilaminas".
ES519615A Expired ES8504666A1 (es) 1981-05-08 1983-02-08 Un procedimiento para la preparacion de nuevas 1,2,3,4-tetrahidro-2-naftilaminas.
ES529311A Granted ES529311A0 (es) 1981-05-08 1984-01-31 Un procedimiento para la preparacion de nuevas 1,2,3,4--tetrahidro-2-naftilaminas.

Country Status (16)

Country Link
US (1) US4876284A (es)
EP (1) EP0064964B1 (es)
JP (1) JPS57192344A (es)
AT (1) ATE8874T1 (es)
AU (2) AU554206B2 (es)
CA (1) CA1236113A (es)
DE (1) DE3260529D1 (es)
DK (1) DK164937C (es)
ES (4) ES8306708A1 (es)
FI (1) FI78067C (es)
GR (1) GR77121B (es)
IE (1) IE53143B1 (es)
IL (1) IL65501A (es)
NO (1) NO152902C (es)
NZ (1) NZ200526A (es)
PH (2) PH18065A (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL65501A (en) * 1981-05-08 1986-04-29 Astra Laekemedel Ab 1-alkyl-2-aminotetralin derivatives,process for their preparation and pharmaceutical compositions containing them
US4743618A (en) * 1983-01-03 1988-05-10 Nelson Research & Development Co. Substituted 2-aminotetralins
US4657925A (en) * 1984-08-13 1987-04-14 Nelson Research & Development Co. Method and compositions for reducing the intraocular pressure of mammals
US4722933A (en) * 1985-12-20 1988-02-02 Nelson Research & Development Co. Substituted 2-aminotetralins
GB2157950B (en) * 1984-05-04 1988-11-02 Nelson Res & Dev Selective d-2 dopamine receptor agonist
AU573828B2 (en) * 1984-05-17 1988-06-23 E.R. Squibb & Sons, Inc. Tetrahydronaphthalenols
EP0168505B1 (en) * 1984-05-22 1989-08-09 Whitby Research Incorporated Substituted 2-aminotetralins and processes for synthesis
DE3718317A1 (de) * 1986-12-10 1988-06-16 Bayer Ag Substituierte basische 2-aminotetraline
US5091526A (en) * 1988-07-29 1992-02-25 Schering Corporation Process for the enantiospecific synthesis of intermediates for hexahydro-benzo[d]-naphtho[2,1-b]azepines
WO1990001476A1 (en) * 1988-07-29 1990-02-22 Schering Corporation A PROCESS FOR THE ENANTIOSPECIFIC SYNTHESIS OF INTERMEDIATES FOR HEXAHYDRO-BENZO[d]NAPHTHO[2,1-b]AZEPINES
CA1335106C (en) * 1989-02-27 1995-04-04 John Mehnert Schaus Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes
SE8901889D0 (sv) * 1989-05-26 1989-05-26 Astra Ab Novel 8-substituted-2-aminotetralines
ES2123500T3 (es) * 1989-05-31 1999-01-16 Upjohn Co Derivados de 8-heterociclil-2-aminotetralina activos sobre el sistema nervioso central.
IT1232160B (it) * 1989-07-31 1992-01-25 Sigma Tau Ind Farmaceuti 2-(n-acil)ammino-6,7-dimetossi tetraline, procedimento per la loro preparazione e composizioni farmaceutiche ad attivita' antiipertensiva che le contengono
CA2071897A1 (en) * 1989-12-28 1991-06-29 Richard A. Glennon Sigma receptor ligands and the use thereof
DK0471515T3 (da) * 1990-08-15 1997-07-21 Lilly Co Eli Ringsubstituerede 2-amino-1,2,3,4-tetrahydronphtalener, 3-aminochromaner og 3-aminothiochromaner
CA2106197A1 (en) * 1991-04-26 1992-10-27 Montford F. Piercey Method of treating/preventing substance abuse
JPH06509069A (ja) * 1991-06-27 1994-10-13 バージニア・コモンウェルス・ユニバーシティ シグマレセプターリガンドおよびその用途
IT1251877B (it) * 1991-09-26 1995-05-26 Zambon Spa Processo per la preparazione di 2-ammino-5,6 dimetossi-tetralina
WO1994022495A1 (en) * 1993-03-31 1994-10-13 The Trustees Of The University Of Pennsylvania Dopamine d-3 and serotonin (5-ht1a) receptor ligands and imaging agents
WO1995000131A1 (en) * 1993-06-23 1995-01-05 Cambridge Neuroscience, Incorporated Sigma receptor ligands and the use thereof
GB9315566D0 (en) * 1993-07-28 1993-09-08 Smithkline Beecham Plc Medicaments
JPH11503116A (ja) * 1995-03-27 1999-03-23 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 二環式アミン誘導体および抗精神病薬としてのそれらの使用
US5646188A (en) * 1995-07-05 1997-07-08 Teva Pharmaceutical Industries, Ltd. Polyamine derivatives of 1-aminoindan
PT1119543E (pt) * 1998-10-07 2005-03-31 Ortho Mcneil Pharm Inc N-aralquilaminotetralinas como ligandos para o receptor y5 do neuropeptido y
EP1506166B1 (en) 2002-05-17 2011-11-16 Janssen Pharmaceutica NV Aminotetralin-derived urea modulators of vanilloid vr1 receptor
EP2098511A1 (en) 2008-03-07 2009-09-09 Solvias AG Process for preparing compounds containing a hydronaphtalene structure with an unsymmetrically substituted benzene ring
DE102010020553A1 (de) 2010-05-14 2011-11-17 Bayer Schering Pharma Aktiengesellschaft Substituierte 8-Alkoxy-2-aminotetralin-Derivate und ihre Verwendung
EP2875003B1 (de) 2012-07-20 2016-11-16 Bayer Pharma Aktiengesellschaft Neue 5-aminotetrahydrochinolin-2-carbonsäuren und ihre verwendung
CA2879456A1 (en) 2012-07-20 2014-01-23 Bayer Pharma Aktiengesellschaft Substituted aminoindane- and aminotetralincarboxylic acids and use thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1017359A (en) * 1972-07-03 1977-09-13 Frederic P. Hauck Substituted cyclic polymethylene phenols
JPS5124508B2 (es) * 1972-08-14 1976-07-24
DE2752659A1 (de) * 1976-12-07 1978-06-08 Sandoz Ag Neue tetralinderivate, ihre herstellung und verwendung
DE3062971D1 (en) * 1979-09-14 1983-06-09 Sandoz Ag Derivatives of tetraline, their preparation and medicaments containing these compounds
AU7179781A (en) * 1980-05-29 1981-12-21 Astra Lakemedel Aktiebolag Therapeutically useful tetralin derivatives
IL65501A (en) * 1981-05-08 1986-04-29 Astra Laekemedel Ab 1-alkyl-2-aminotetralin derivatives,process for their preparation and pharmaceutical compositions containing them
FR2512814A1 (fr) * 1981-09-16 1983-03-18 Synthelabo Derives d'amino-2 tetrahydro-1,2,3,4 naphtalene, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
ES8506591A1 (es) 1985-08-01
CA1236113A (en) 1988-05-03
ES519615A0 (es) 1985-05-01
FI78067B (fi) 1989-02-28
ES8602603A1 (es) 1985-12-01
ES8504666A1 (es) 1985-05-01
ES529311A0 (es) 1985-08-01
GR77121B (es) 1984-09-07
NO152902B (no) 1985-09-02
NZ200526A (en) 1985-09-13
EP0064964A1 (en) 1982-11-17
AU2587984A (en) 1984-06-28
FI821598L (fi) 1982-11-09
NO821494L (no) 1982-11-09
ATE8874T1 (de) 1984-08-15
DK202882A (da) 1982-11-09
NO152902C (no) 1985-12-11
JPS57192344A (en) 1982-11-26
PH19585A (en) 1986-05-26
IL65501A (en) 1986-04-29
AU8340982A (en) 1982-11-11
DE3260529D1 (en) 1984-09-13
IE821076L (en) 1982-11-08
IL65501A0 (en) 1982-07-30
AU554206B2 (en) 1986-08-14
IE53143B1 (en) 1988-07-20
AU572497B2 (en) 1988-05-12
PH18065A (en) 1985-03-18
ES511986A0 (es) 1983-06-01
FI78067C (fi) 1989-06-12
DK164937B (da) 1992-09-14
EP0064964B1 (en) 1984-08-08
JPH0419221B2 (es) 1992-03-30
DK164937C (da) 1993-02-01
US4876284A (en) 1989-10-24
FI821598A0 (fi) 1982-05-06
ES8306708A1 (es) 1983-06-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000601