ES511986A0 - "un procedimiento para la preparacion de nuevas 1,2,3,4 tetrahidro 2 naftilaminas". - Google Patents

"un procedimiento para la preparacion de nuevas 1,2,3,4 tetrahidro 2 naftilaminas".

Info

Publication number
ES511986A0
ES511986A0 ES511986A ES511986A ES511986A0 ES 511986 A0 ES511986 A0 ES 511986A0 ES 511986 A ES511986 A ES 511986A ES 511986 A ES511986 A ES 511986A ES 511986 A0 ES511986 A0 ES 511986A0
Authority
ES
Spain
Prior art keywords
carbon atoms
group
alkyl group
compounds
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES511986A
Other languages
English (en)
Other versions
ES8306708A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astra Lakemedel AB
Original Assignee
Astra Lakemedel AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Lakemedel AB filed Critical Astra Lakemedel AB
Publication of ES8306708A1 publication Critical patent/ES8306708A1/es
Publication of ES511986A0 publication Critical patent/ES511986A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/64Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/26Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
ES511986A 1981-05-08 1982-05-07 "un procedimiento para la preparacion de nuevas 1,2,3,4 tetrahidro 2 naftilaminas". Granted ES511986A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8102908 1981-05-08

Publications (2)

Publication Number Publication Date
ES8306708A1 ES8306708A1 (es) 1983-06-01
ES511986A0 true ES511986A0 (es) 1983-06-01

Family

ID=20343779

Family Applications (4)

Application Number Title Priority Date Filing Date
ES511986A Granted ES511986A0 (es) 1981-05-08 1982-05-07 "un procedimiento para la preparacion de nuevas 1,2,3,4 tetrahidro 2 naftilaminas".
ES519615A Granted ES519615A0 (es) 1981-05-08 1983-02-08 Un procedimiento para la preparacion de nuevas 1,2,3,4-tetrahidro-2-naftilaminas.
ES529311A Granted ES529311A0 (es) 1981-05-08 1984-01-31 Un procedimiento para la preparacion de nuevas 1,2,3,4--tetrahidro-2-naftilaminas.
ES535882A Granted ES535882A0 (es) 1981-05-08 1984-09-13 Un procedimiento para la preparacion de nuevas 1,2,3,4-tetrahidro-2-naftilaminas

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES519615A Granted ES519615A0 (es) 1981-05-08 1983-02-08 Un procedimiento para la preparacion de nuevas 1,2,3,4-tetrahidro-2-naftilaminas.
ES529311A Granted ES529311A0 (es) 1981-05-08 1984-01-31 Un procedimiento para la preparacion de nuevas 1,2,3,4--tetrahidro-2-naftilaminas.
ES535882A Granted ES535882A0 (es) 1981-05-08 1984-09-13 Un procedimiento para la preparacion de nuevas 1,2,3,4-tetrahidro-2-naftilaminas

Country Status (16)

Country Link
US (1) US4876284A (es)
EP (1) EP0064964B1 (es)
JP (1) JPS57192344A (es)
AT (1) ATE8874T1 (es)
AU (2) AU554206B2 (es)
CA (1) CA1236113A (es)
DE (1) DE3260529D1 (es)
DK (1) DK164937C (es)
ES (4) ES511986A0 (es)
FI (1) FI78067C (es)
GR (1) GR77121B (es)
IE (1) IE53143B1 (es)
IL (1) IL65501A (es)
NO (1) NO152902C (es)
NZ (1) NZ200526A (es)
PH (2) PH18065A (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL65501A (en) * 1981-05-08 1986-04-29 Astra Laekemedel Ab 1-alkyl-2-aminotetralin derivatives,process for their preparation and pharmaceutical compositions containing them
US4743618A (en) * 1983-01-03 1988-05-10 Nelson Research & Development Co. Substituted 2-aminotetralins
US4722933A (en) * 1985-12-20 1988-02-02 Nelson Research & Development Co. Substituted 2-aminotetralins
US4657925A (en) * 1984-08-13 1987-04-14 Nelson Research & Development Co. Method and compositions for reducing the intraocular pressure of mammals
GB2157950B (en) * 1984-05-04 1988-11-02 Nelson Res & Dev Selective d-2 dopamine receptor agonist
AU573828B2 (en) * 1984-05-17 1988-06-23 E.R. Squibb & Sons, Inc. Tetrahydronaphthalenols
DE3479314D1 (en) * 1984-05-22 1989-09-14 Nelson Res & Dev Substituted 2-aminotetralins and processes for synthesis
DE3718317A1 (de) * 1986-12-10 1988-06-16 Bayer Ag Substituierte basische 2-aminotetraline
JPH03505735A (ja) * 1988-07-29 1991-12-12 シェリング・コーポレーション ヘキサヒドロ―ベンゾ[d]―ナフト[2,1―b]アゼピンのための中間体の対掌体特異的合成のための方法
US5091526A (en) * 1988-07-29 1992-02-25 Schering Corporation Process for the enantiospecific synthesis of intermediates for hexahydro-benzo[d]-naphtho[2,1-b]azepines
CA1335106C (en) * 1989-02-27 1995-04-04 John Mehnert Schaus Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes
SE8901889D0 (sv) * 1989-05-26 1989-05-26 Astra Ab Novel 8-substituted-2-aminotetralines
RU2086535C1 (ru) * 1989-05-31 1997-08-10 Дзе Апджон Компани Производные 1,2,3,4-тетрагидро-2-нафтиламина
IT1232160B (it) * 1989-07-31 1992-01-25 Sigma Tau Ind Farmaceuti 2-(n-acil)ammino-6,7-dimetossi tetraline, procedimento per la loro preparazione e composizioni farmaceutiche ad attivita' antiipertensiva che le contengono
CA2071897A1 (en) * 1989-12-28 1991-06-29 Richard A. Glennon Sigma receptor ligands and the use thereof
DK0471515T3 (da) * 1990-08-15 1997-07-21 Lilly Co Eli Ringsubstituerede 2-amino-1,2,3,4-tetrahydronphtalener, 3-aminochromaner og 3-aminothiochromaner
JPH06506951A (ja) * 1991-04-26 1994-08-04 ジ・アップジョン・カンパニー 物質乱用の治療/予防方法
EP0591426A4 (en) * 1991-06-27 1996-08-21 Univ Virginia Commonwealth Sigma receptor ligands and the use thereof
IT1251877B (it) * 1991-09-26 1995-05-26 Zambon Spa Processo per la preparazione di 2-ammino-5,6 dimetossi-tetralina
EP0697894A4 (en) * 1993-03-31 1996-05-01 Univ Pennsylvania DOPAMINE D-3 AND SEROTONIN (5-HT 1A) RECEPTOR LIGANDS AND IMAGING AGENTS
WO1995000131A1 (en) * 1993-06-23 1995-01-05 Cambridge Neuroscience, Incorporated Sigma receptor ligands and the use thereof
GB9315566D0 (en) * 1993-07-28 1993-09-08 Smithkline Beecham Plc Medicaments
US6008219A (en) * 1995-03-27 1999-12-28 Smithkline Beech P.L.C. Bicyclic amine derivatives and their use as anti-psychotic agents
US5646188A (en) * 1995-07-05 1997-07-08 Teva Pharmaceutical Industries, Ltd. Polyamine derivatives of 1-aminoindan
ES2235521T3 (es) 1998-10-07 2005-07-01 Ortho-Mcneil Pharmaceutical, Inc. N-aralquilaminotetralina como ligando para el neuropeptido y el receptor y5.
AU2003241453A1 (en) 2002-05-17 2003-12-02 Janssen Pharmaceutica N.V. Aminotetralin-derived urea modulators of vanilloid vr1 receptor
EP2098511A1 (en) 2008-03-07 2009-09-09 Solvias AG Process for preparing compounds containing a hydronaphtalene structure with an unsymmetrically substituted benzene ring
DE102010020553A1 (de) 2010-05-14 2011-11-17 Bayer Schering Pharma Aktiengesellschaft Substituierte 8-Alkoxy-2-aminotetralin-Derivate und ihre Verwendung
CA2879456A1 (en) 2012-07-20 2014-01-23 Bayer Pharma Aktiengesellschaft Substituted aminoindane- and aminotetralincarboxylic acids and use thereof
PT2875003T (pt) 2012-07-20 2017-02-16 Bayer Pharma AG Novos ácidos 5-amino-tetra-hidroquinolina-2-carboxílicos e sua utilização

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1017359A (en) * 1972-07-03 1977-09-13 Frederic P. Hauck Substituted cyclic polymethylene phenols
JPS5124508B2 (es) * 1972-08-14 1976-07-24
DE2752659A1 (de) * 1976-12-07 1978-06-08 Sandoz Ag Neue tetralinderivate, ihre herstellung und verwendung
DE3062971D1 (en) * 1979-09-14 1983-06-09 Sandoz Ag Derivatives of tetraline, their preparation and medicaments containing these compounds
AU7179781A (en) * 1980-05-29 1981-12-21 Astra Lakemedel Aktiebolag Therapeutically useful tetralin derivatives
IL65501A (en) * 1981-05-08 1986-04-29 Astra Laekemedel Ab 1-alkyl-2-aminotetralin derivatives,process for their preparation and pharmaceutical compositions containing them
FR2512814A1 (fr) * 1981-09-16 1983-03-18 Synthelabo Derives d'amino-2 tetrahydro-1,2,3,4 naphtalene, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
PH19585A (en) 1986-05-26
ES8306708A1 (es) 1983-06-01
IL65501A (en) 1986-04-29
DK164937B (da) 1992-09-14
ES8602603A1 (es) 1985-12-01
AU2587984A (en) 1984-06-28
NZ200526A (en) 1985-09-13
NO821494L (no) 1982-11-09
AU572497B2 (en) 1988-05-12
ES8504666A1 (es) 1985-05-01
FI821598A0 (fi) 1982-05-06
CA1236113A (en) 1988-05-03
IE53143B1 (en) 1988-07-20
AU8340982A (en) 1982-11-11
ES519615A0 (es) 1985-05-01
JPH0419221B2 (es) 1992-03-30
NO152902B (no) 1985-09-02
AU554206B2 (en) 1986-08-14
IE821076L (en) 1982-11-08
PH18065A (en) 1985-03-18
JPS57192344A (en) 1982-11-26
ES8506591A1 (es) 1985-08-01
FI78067C (fi) 1989-06-12
FI821598L (fi) 1982-11-09
ATE8874T1 (de) 1984-08-15
EP0064964B1 (en) 1984-08-08
ES535882A0 (es) 1985-12-01
DK202882A (da) 1982-11-09
DK164937C (da) 1993-02-01
EP0064964A1 (en) 1982-11-17
GR77121B (es) 1984-09-07
FI78067B (fi) 1989-02-28
ES529311A0 (es) 1985-08-01
DE3260529D1 (en) 1984-09-13
NO152902C (no) 1985-12-11
IL65501A0 (en) 1982-07-30
US4876284A (en) 1989-10-24

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19990201