NO996429D0 - 2-substituerte 4,5-diarylimidazoler - Google Patents

2-substituerte 4,5-diarylimidazoler

Info

Publication number
NO996429D0
NO996429D0 NO996429A NO996429A NO996429D0 NO 996429 D0 NO996429 D0 NO 996429D0 NO 996429 A NO996429 A NO 996429A NO 996429 A NO996429 A NO 996429A NO 996429 D0 NO996429 D0 NO 996429D0
Authority
NO
Norway
Prior art keywords
diarylimidazoles
substituted
Prior art date
Application number
NO996429A
Other languages
English (en)
Norwegian (no)
Other versions
NO996429L (no
Inventor
Lsszlo Revesz
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO996429D0 publication Critical patent/NO996429D0/no
Publication of NO996429L publication Critical patent/NO996429L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
NO996429A 1997-06-30 1999-12-23 2-substituerte 4,5-diarylimidazoler NO996429L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9713726.9A GB9713726D0 (en) 1997-06-30 1997-06-30 Organic compounds
PCT/EP1998/003930 WO1999001449A1 (en) 1997-06-30 1998-06-26 2-substituted 4,5-diaryl imidazoles

Publications (2)

Publication Number Publication Date
NO996429D0 true NO996429D0 (no) 1999-12-23
NO996429L NO996429L (no) 1999-12-23

Family

ID=10815101

Family Applications (1)

Application Number Title Priority Date Filing Date
NO996429A NO996429L (no) 1997-06-30 1999-12-23 2-substituerte 4,5-diarylimidazoler

Country Status (28)

Country Link
US (1) US6300347B1 (de)
EP (2) EP0993456B1 (de)
JP (1) JP3704362B2 (de)
KR (1) KR20010013215A (de)
CN (1) CN1261885A (de)
AR (1) AR014886A1 (de)
AT (1) ATE275557T1 (de)
AU (1) AU744411B2 (de)
BR (1) BR9810955A (de)
CA (1) CA2291758A1 (de)
CO (1) CO4940462A1 (de)
DE (1) DE69826127T2 (de)
ES (1) ES2226164T3 (de)
GB (1) GB9713726D0 (de)
HU (1) HUP0003351A3 (de)
ID (1) ID23385A (de)
IL (1) IL133034A0 (de)
NO (1) NO996429L (de)
NZ (1) NZ501275A (de)
PE (1) PE99999A1 (de)
PL (1) PL337057A1 (de)
PT (1) PT993456E (de)
RU (1) RU2214408C2 (de)
SK (1) SK186599A3 (de)
TR (1) TR199903278T2 (de)
TW (1) TW429258B (de)
WO (1) WO1999001449A1 (de)
ZA (1) ZA985656B (de)

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ATE425142T1 (de) * 1999-04-23 2009-03-15 Vertex Pharma Inhibitoren von c-jun n-terminal kinasen (jnk)
US6291457B1 (en) 1999-07-01 2001-09-18 Merck & Co., Inc. Compounds having cytokine inhibitory activity
US7122666B2 (en) 1999-07-21 2006-10-17 Sankyo Company, Limited Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses
ES2254238T3 (es) * 1999-10-27 2006-06-16 Novartis Ag Compuestos de tiazol e imidazo(4,5-b)piridina y su uso farmaceutico.
PT1140939E (pt) 1999-11-10 2005-05-31 Ortho Mcneil Pharm Inc 2-aril-3-(heteroaril)- imidazo [1,2-alfa] pirimidinas substituidas, e formulacoes farmaceuticas e metodos relacionados
US6808902B1 (en) 1999-11-12 2004-10-26 Amgen Inc. Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
WO2001037835A1 (en) * 1999-11-22 2001-05-31 Smithkline Beecham Plc. Novel compounds
WO2001038312A1 (en) 1999-11-23 2001-05-31 Smithkline Beecham Corporation 3,4-DIHYDRO-(1H)QUINAZOLIN-2-ONE COMPOUNDS AS CSBP/p38 KINASE INHIBITORS
US7612065B2 (en) 2000-04-21 2009-11-03 Vertex Pharmaceuticals Incorporated Inhibitors of c-JUN N-terminal kinases (JNK)
ES2251582T3 (es) 2001-03-09 2006-05-01 Pfizer Products Inc. Compuestos antiinflamatorios de bencimidazol.
ATE323701T1 (de) 2001-03-09 2006-05-15 Pfizer Prod Inc Triazolopyridine als entzündungshemmende mittel
ATE304009T1 (de) 2001-04-04 2005-09-15 Pfizer Prod Inc Neue benzotriazole mit entzündungshemmender wirkung
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DE60310730T2 (de) 2002-07-09 2007-05-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmazeutische zusammensetzungen aus anticholinergica und p38 kinase hemmern zur behandlung von erkrankungen der atemwege
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US7012143B2 (en) 2002-08-30 2006-03-14 Dombroski Mark A Cycloalkyl-[4-(difluorophenyl)-oxazol-5-yl]-triazolo-pyridines
PA8579601A1 (es) 2002-08-30 2004-05-07 Pfizer Prod Inc Compuestos antiinflamatorios de di y trifloruro-triazolo-piridinas
US7005523B2 (en) 2002-08-30 2006-02-28 Pfizer Inc. Cycloalkyl-[4-(trifluorophenyl)-oxazol-5yl]-triazolo-pyridines
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UA80295C2 (en) 2002-09-06 2007-09-10 Biogen Inc Pyrazolopyridines and using the same
AU2003299652A1 (en) * 2002-12-06 2004-06-30 Scios Inc. Methods for treating diabetes
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US8361467B2 (en) 2003-07-30 2013-01-29 Depuy Spine, Inc. Trans-capsular administration of high specificity cytokine inhibitors into orthopedic joints
US7253164B2 (en) * 2003-07-31 2007-08-07 Irm Llc Bicyclic compounds and compositions as PDF inhibitors
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US8895540B2 (en) 2003-11-26 2014-11-25 DePuy Synthes Products, LLC Local intraosseous administration of bone forming agents and anti-resorptive agents, and devices therefor
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US20060035893A1 (en) 2004-08-07 2006-02-16 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
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ATE469893T1 (de) * 2005-02-28 2010-06-15 Merckle Gmbh 2-sulfinyl- und 2-sulfonyl-substituierte imidazolderivate und deren verwendung als cytokininhibitoren
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JP5324785B2 (ja) 2005-10-28 2013-10-23 武田薬品工業株式会社 複素環アミド化合物及びその用途
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AU2008261030A1 (en) * 2007-06-05 2008-12-11 Western States Biopharmaceuticals, Inc. T-cell cytokine-inducing surface molecules and methods of use
US8986696B2 (en) * 2007-12-21 2015-03-24 Depuy Mitek, Inc. Trans-capsular administration of p38 map kinase inhibitors into orthopedic joints
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EP2108641A1 (de) 2008-04-11 2009-10-14 Laboratorios Almirall, S.A. Neue substituierte Spiro[Cycloalkyl-1,3'-indo]-2'(1'H)-on-Derivate und ihre Verwendung als p38 mitogen-activated Kinase Inhibitoren
EP2113503A1 (de) 2008-04-28 2009-11-04 Laboratorios Almirall, S.A. Neue substituierte Indolin-2-on- Derivate und ihre Verwendung als p39 mitogen-activated Kinase Inhibitoren
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EP2516668B1 (de) * 2009-12-22 2016-04-06 Csir Hemmung der aktivität von kinase- und synthetaseenzymen
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Also Published As

Publication number Publication date
ZA985656B (en) 1998-12-30
ES2226164T3 (es) 2005-03-16
AR014886A1 (es) 2001-04-11
NZ501275A (en) 2002-04-26
WO1999001449A1 (en) 1999-01-14
KR20010013215A (ko) 2001-02-26
EP0993456A1 (de) 2000-04-19
DE69826127D1 (de) 2004-10-14
JP2001506280A (ja) 2001-05-15
EP1396491A2 (de) 2004-03-10
EP0993456B1 (de) 2004-09-08
AU8801598A (en) 1999-01-25
TR199903278T2 (en) 2000-07-21
EP1396491A3 (de) 2004-06-30
HUP0003351A2 (hu) 2001-06-28
CO4940462A1 (es) 2000-07-24
DE69826127T2 (de) 2005-09-29
CA2291758A1 (en) 1999-01-14
TW429258B (en) 2001-04-11
RU2214408C2 (ru) 2003-10-20
IL133034A0 (en) 2001-03-19
ATE275557T1 (de) 2004-09-15
BR9810955A (pt) 2000-09-26
ID23385A (id) 2000-04-20
HUP0003351A3 (en) 2002-01-28
GB9713726D0 (en) 1997-09-03
NO996429L (no) 1999-12-23
PT993456E (pt) 2005-01-31
PL337057A1 (en) 2000-07-31
US6300347B1 (en) 2001-10-09
PE99999A1 (es) 1999-11-01
SK186599A3 (en) 2000-06-12
AU744411B2 (en) 2002-02-21
CN1261885A (zh) 2000-08-02
JP3704362B2 (ja) 2005-10-12

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