NO996366L - Arylkarboksylsyre- og tetrazolderivater - Google Patents

Arylkarboksylsyre- og tetrazolderivater

Info

Publication number
NO996366L
NO996366L NO996366A NO996366A NO996366L NO 996366 L NO996366 L NO 996366L NO 996366 A NO996366 A NO 996366A NO 996366 A NO996366 A NO 996366A NO 996366 L NO996366 L NO 996366L
Authority
NO
Norway
Prior art keywords
carboxylic acid
aryl carboxylic
tetrazole derivatives
tetrazole
derivatives
Prior art date
Application number
NO996366A
Other languages
English (en)
Other versions
NO996366D0 (no
NO316171B1 (no
Inventor
Francisco Javier Lopez-Tapia
Alexander Victor Muehldorf
Counde O'yang
Daniel Lee Severance
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO996366D0 publication Critical patent/NO996366D0/no
Publication of NO996366L publication Critical patent/NO996366L/no
Publication of NO316171B1 publication Critical patent/NO316171B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/26—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
    • C07C271/28—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a non-condensed six-membered aromatic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
NO19996366A 1998-12-23 1999-12-21 Arylkarboksylsyre- og tetrazolderivater, farmasöytisk preparat samt fremgangsmåte for fremstilling og anvendelse derav NO316171B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11344698P 1998-12-23 1998-12-23
US15181499P 1999-08-30 1999-08-30

Publications (3)

Publication Number Publication Date
NO996366D0 NO996366D0 (no) 1999-12-21
NO996366L true NO996366L (no) 2000-06-26
NO316171B1 NO316171B1 (no) 2003-12-22

Family

ID=26811078

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19996366A NO316171B1 (no) 1998-12-23 1999-12-21 Arylkarboksylsyre- og tetrazolderivater, farmasöytisk preparat samt fremgangsmåte for fremstilling og anvendelse derav

Country Status (29)

Country Link
US (1) US6335459B1 (no)
EP (1) EP1013639B1 (no)
JP (1) JP3415085B2 (no)
KR (1) KR100378335B1 (no)
CN (1) CN1167670C (no)
AR (1) AR029320A1 (no)
AT (1) ATE251125T1 (no)
AU (1) AU735640B2 (no)
BR (1) BR9905974A (no)
CA (1) CA2292921C (no)
DE (1) DE69911726T2 (no)
DK (1) DK1013639T3 (no)
ES (1) ES2207108T3 (no)
HR (1) HRP990394A2 (no)
HU (1) HUP9904659A3 (no)
ID (1) ID25983A (no)
IL (1) IL133578A (no)
MA (1) MA26713A1 (no)
NO (1) NO316171B1 (no)
NZ (1) NZ501891A (no)
PE (1) PE20001368A1 (no)
PL (1) PL337419A1 (no)
PT (1) PT1013639E (no)
RU (1) RU2179969C2 (no)
SG (1) SG90086A1 (no)
TR (1) TR199903310A2 (no)
TW (1) TWI221834B (no)
UY (1) UY25876A1 (no)
YU (1) YU69699A (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9828442D0 (en) 1998-12-24 1999-02-17 Karobio Ab Novel thyroid receptor ligands and method II
SE0100158D0 (sv) * 2001-01-19 2001-01-19 Synphora Ab Novel method and composition for local treatment of Meniere´s disease and tinnitus
EP1368345B1 (en) * 2001-03-02 2006-03-22 F. Hoffmann-La Roche AG Alkoxycarbonylamino heteroaryl carboxylic acid derivatives as ip antagonists
CN100477995C (zh) 2003-05-09 2009-04-15 东丽株式会社 增强剂
RU2268037C1 (ru) * 2004-04-22 2006-01-20 Германов Евгений Павлович Лекарственное средство
UA93548C2 (uk) 2006-05-05 2011-02-25 Айерем Елелсі Сполуки та композиції як модулятори хеджхогівського сигнального шляху
US9669381B2 (en) 2007-06-27 2017-06-06 Hrd Corporation System and process for hydrocracking
CN110003123B (zh) 2008-03-18 2023-06-23 艾尼纳制药公司 用于治疗前列环素(pgi2)受体相关病症的pgi2受体调节剂
CA2730599C (en) 2008-07-23 2016-09-13 Toray Industries, Inc. Therapeutic agent for chronic renal failure
JP2013529595A (ja) 2010-06-11 2013-07-22 ローズ テクノロジーズ 第３級アミンのｎ−脱アルキル化方法
ES2645725T3 (es) 2010-06-11 2017-12-07 Rhodes Technologies Procesos catalizados por metales de transición para la preparación de compuestos de N-alilo y uso de los mismos
EP3977985B1 (en) 2017-03-01 2023-09-06 Arena Pharmaceuticals, Inc. Compositions comprising pgi2-receptor agonists and processes for the preparation thereof
WO2023158634A1 (en) 2022-02-15 2023-08-24 United Therapeutics Corporation Crystalline prostacyclin (ip) receptor agonist and uses thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1079414A (en) 1965-06-30 1967-08-16 Smith & Nephew Derivatives of acetic acid and a process for their preparation
GB1185539A (en) 1967-11-03 1970-03-25 Smith & Nephew Substituted Tetrazoles
DE2432560A1 (de) 1974-07-06 1976-01-22 Boehringer Mannheim Gmbh Neue phenoxyalkylcarbonsaeurederivate und verfahren zur herstellung derselben
JPS5832859A (ja) 1981-08-20 1983-02-25 Dainippon Pharmaceut Co Ltd Ｎ，ｎ−ジメチルカルバミン酸ベンジルエステル誘導体
JPH0725725B2 (ja) 1987-07-23 1995-03-22 保土谷化学工業株式会社 ベンズアミド誘導体
US5084466A (en) 1989-01-31 1992-01-28 Hoffmann-La Roche Inc. Novel carboxamide pyridine compounds which have useful pharmaceutical utility
CA2090283A1 (en) 1992-02-28 1993-08-29 Nobuyuki Hamanaka Phenoxyacetic acid derivatives
CA2183063A1 (en) 1994-02-10 1995-08-17 Atsushi Ichikawa Prostaglandin i2 receptor
KR100383305B1 (ko) 1994-03-10 2003-11-01 후지사와 야꾸힝 고교 가부시키가이샤 프로스타글란딘i₂작용물질로서의나프탈렌유도체
US5753700A (en) 1994-12-28 1998-05-19 Ono Pharmaceutical Co., Ltd. Naphthyloxyacetic acid derivatives
TW401408B (en) 1995-07-21 2000-08-11 Fujisawa Pharmaceutical Co Heterocyclic compounds having prostaglandin I2 agonism
WO1997005091A1 (en) 1995-07-26 1997-02-13 Ono Pharmaceutical Co., Ltd. Naphthyloxyacetic acid derivatives and drugs comprising the same as active ingredients
DE19619445C1 (de) * 1996-05-14 1997-09-25 Bayer Ag Verfahren zur Herstellung von optisch aktiver N-Phenylcarbamat-milchsäure
AUPP029197A0 (en) 1997-11-10 1997-12-04 Fujisawa Pharmaceutical Co., Ltd. Benzocycloheptene derivatives
AUPP109097A0 (en) 1997-12-22 1998-01-22 Fujisawa Pharmaceutical Co., Ltd. Napthalene derivatives

Also Published As

Publication number Publication date
MA26713A1 (fr) 2004-12-20
HUP9904659A2 (hu) 2000-11-28
YU69699A (sh) 2001-12-26
ID25983A (id) 2000-11-16
DE69911726D1 (de) 2003-11-06
JP3415085B2 (ja) 2003-06-09
HUP9904659A3 (en) 2000-12-28
RU2179969C2 (ru) 2002-02-27
TR199903310A3 (tr) 2000-10-23
US6335459B1 (en) 2002-01-01
BR9905974A (pt) 2000-09-12
DK1013639T3 (da) 2004-02-09
NZ501891A (en) 2001-10-26
AU6534099A (en) 2000-07-06
IL133578A0 (en) 2001-04-30
PL337419A1 (en) 2000-07-03
DE69911726T2 (de) 2004-07-29
KR20000048322A (ko) 2000-07-25
HRP990394A2 (en) 2000-08-31
ATE251125T1 (de) 2003-10-15
TWI221834B (en) 2004-10-11
CA2292921C (en) 2004-08-17
PE20001368A1 (es) 2000-12-14
AR029320A1 (es) 2003-06-25
KR100378335B1 (ko) 2003-03-29
CN1167670C (zh) 2004-09-22
HU9904659D0 (en) 2000-02-28
ES2207108T3 (es) 2004-05-16
EP1013639A1 (en) 2000-06-28
NO996366D0 (no) 1999-12-21
CA2292921A1 (en) 2000-06-23
PT1013639E (pt) 2004-02-27
IL133578A (en) 2004-07-25
TR199903310A2 (xx) 2000-10-23
NO316171B1 (no) 2003-12-22
AU735640B2 (en) 2001-07-12
CN1266054A (zh) 2000-09-13
SG90086A1 (en) 2002-07-23
JP2000191523A (ja) 2000-07-11
UY25876A1 (es) 2001-07-31
EP1013639B1 (en) 2003-10-01

Similar Documents

Publication Publication Date Title
ATE248812T1 (de) Arylsulfonylhydroxamsäurederivate
DE69918278D1 (de) Substituierte indolalkansäure
IS5340A (is) Arýloxýarýlsúlfónýlamínó hýdroxamsýru afleiður
DE69703385D1 (de) Alkoxyessigsäure-derivate
NO990821D0 (no) Arylsulfonylamino-hydroksaminsyre-derivater
ATE228995T1 (de) Aminomethylcarbonsäurederivate
ATE239005T1 (de) (4-sulfonylamino)-tetrahydropyran-4-carbonsäure hydroxamiden
NO20000877L (no) Forbedret syrekorrosjonsinhibitor
IS5744A (is) Nýjar 3-arýl-própíónsýruafleiður og -hliðstæður
PT1240172E (pt) Novos acidos aminopropilfosfinicos
DE60043730D1 (de) Arylsulfonamid-substituierte hydroxamsäure-derivate
NO996366D0 (no) Arylkarboksylsyre- og tetrazolderivater
IS5562A (is) Nýjar díhýdroxýhexanósýru afleiður
DE60024754D1 (de) Aufzeichnungsgerät
PT878467E (pt) Acidos 6-aminotetra-hidroisoquinolinacarboxilicos e 7-aminotetra-hidroisoquinolinacarboxilicos substituidos
DE69718338D1 (de) 3-alkoxyisoxazol-4-yl-substituierte 2-aminocarbonsäurederivate
DE60032034D1 (de) Aufzeichnungsgerät
NO994386D0 (no) 2-substituerte benzoylcykloalkyl-1-karboksylsyrederivater
FR2791941B3 (fr) Remorque
DE60030196D1 (de) Aufzeichnungsgerät
EE04061B1 (et) Metüleenbisfosfoonhappe derivaadid
DE69713354D1 (de) Hydroxamsäure-derivate
ZA997773B (en) Aryl carboxylic acid and tetrazole derivatives.
BR1100402A (pt) Derivados do ácido quinolona carboxìlico
SE9801991D0 (sv) New 3-aryl-2-hydroxypropionic acid derivative II