DK1013639T3 - Arylcarboxylsyre og tetrazolderivater, som indeholder en carbamoyloxyenhed - Google Patents

Arylcarboxylsyre og tetrazolderivater, som indeholder en carbamoyloxyenhed

Info

Publication number
DK1013639T3
DK1013639T3 DK99125027T DK99125027T DK1013639T3 DK 1013639 T3 DK1013639 T3 DK 1013639T3 DK 99125027 T DK99125027 T DK 99125027T DK 99125027 T DK99125027 T DK 99125027T DK 1013639 T3 DK1013639 T3 DK 1013639T3
Authority
DK
Denmark
Prior art keywords
carbamoyloxy
unit
carboxylic acid
derivatives containing
aryl carboxylic
Prior art date
Application number
DK99125027T
Other languages
English (en)
Inventor
Francisco Javier Lopez-Tapia
Alexander Victor Muehldorf
Counde O'yang
Daniel Lee Severance
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK1013639T3 publication Critical patent/DK1013639T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/26Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
    • C07C271/28Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a non-condensed six-membered aromatic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
DK99125027T 1998-12-23 1999-12-15 Arylcarboxylsyre og tetrazolderivater, som indeholder en carbamoyloxyenhed DK1013639T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11344698P 1998-12-23 1998-12-23
US15181499P 1999-08-30 1999-08-30

Publications (1)

Publication Number Publication Date
DK1013639T3 true DK1013639T3 (da) 2004-02-09

Family

ID=26811078

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99125027T DK1013639T3 (da) 1998-12-23 1999-12-15 Arylcarboxylsyre og tetrazolderivater, som indeholder en carbamoyloxyenhed

Country Status (29)

Country Link
US (1) US6335459B1 (da)
EP (1) EP1013639B1 (da)
JP (1) JP3415085B2 (da)
KR (1) KR100378335B1 (da)
CN (1) CN1167670C (da)
AR (1) AR029320A1 (da)
AT (1) ATE251125T1 (da)
AU (1) AU735640B2 (da)
BR (1) BR9905974A (da)
CA (1) CA2292921C (da)
DE (1) DE69911726T2 (da)
DK (1) DK1013639T3 (da)
ES (1) ES2207108T3 (da)
HR (1) HRP990394A2 (da)
HU (1) HUP9904659A3 (da)
ID (1) ID25983A (da)
IL (1) IL133578A (da)
MA (1) MA26713A1 (da)
NO (1) NO316171B1 (da)
NZ (1) NZ501891A (da)
PE (1) PE20001368A1 (da)
PL (1) PL337419A1 (da)
PT (1) PT1013639E (da)
RU (1) RU2179969C2 (da)
SG (1) SG90086A1 (da)
TR (1) TR199903310A3 (da)
TW (1) TWI221834B (da)
UY (1) UY25876A1 (da)
YU (1) YU69699A (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9828442D0 (en) 1998-12-24 1999-02-17 Karobio Ab Novel thyroid receptor ligands and method II
SE0100158D0 (sv) * 2001-01-19 2001-01-19 Synphora Ab Novel method and composition for local treatment of Meniere´s disease and tinnitus
CA2438813C (en) * 2001-03-02 2008-07-29 F. Hoffmann-La Roche Ag Alkoxycarbonylamino heteroaryl carboxylic acid derivatives as ip antagonists
EP1627638B1 (en) 2003-05-09 2017-07-12 Toray Industries, Inc. Beraprost and a renin-angiotensin system inhibitor for use in the treatment of renal diseases
UA93548C2 (uk) 2006-05-05 2011-02-25 Айерем Елелсі Сполуки та композиції як модулятори хеджхогівського сигнального шляху
US9669381B2 (en) 2007-06-27 2017-06-06 Hrd Corporation System and process for hydrocracking
KR20230085944A (ko) 2008-03-18 2023-06-14 아레나 파마슈티칼스, 인크. 프로스타시클린 (pgi2) 수용체와 관련된 장애의 치료에 유용한 상기 수용체의 조절제
US8575175B2 (en) * 2008-07-23 2013-11-05 Toray Industries, Inc. Therapeutic agent for chronic renal failure
WO2011154826A1 (en) 2010-06-11 2011-12-15 Rhodes Technologies Process for n-dealkylation of tertiary amines
EP2995614B8 (en) 2010-06-11 2018-03-28 Rhodes Technologies Inc. Transition metal-catalyzed processes for the preparation of n-allyl compounds and use thereof
KR20220119169A (ko) 2017-03-01 2022-08-26 아레나 파마슈티칼스, 인크. Pgi2-수용체 효능제를 포함하는 조성물 및 그의 제조 방법

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1079414A (en) 1965-06-30 1967-08-16 Smith & Nephew Derivatives of acetic acid and a process for their preparation
GB1185539A (en) 1967-11-03 1970-03-25 Smith & Nephew Substituted Tetrazoles
DE2432560A1 (de) 1974-07-06 1976-01-22 Boehringer Mannheim Gmbh Neue phenoxyalkylcarbonsaeurederivate und verfahren zur herstellung derselben
JPS5832859A (ja) 1981-08-20 1983-02-25 Dainippon Pharmaceut Co Ltd N,n−ジメチルカルバミン酸ベンジルエステル誘導体
JPH0725725B2 (ja) 1987-07-23 1995-03-22 保土谷化学工業株式会社 ベンズアミド誘導体
US5084466A (en) 1989-01-31 1992-01-28 Hoffmann-La Roche Inc. Novel carboxamide pyridine compounds which have useful pharmaceutical utility
CA2090283A1 (en) 1992-02-28 1993-08-29 Nobuyuki Hamanaka Phenoxyacetic acid derivatives
EP0753528A4 (en) 1994-02-10 1999-03-10 Ono Pharmaceutical Co PROTAGLANDIN I 2? RECEPTOR
AU688871B2 (en) 1994-03-10 1998-03-19 Astellas Pharma Inc. Naphthalene derivatives as prostaglandin I2 agonists
US5753700A (en) 1994-12-28 1998-05-19 Ono Pharmaceutical Co., Ltd. Naphthyloxyacetic acid derivatives
TW401408B (en) 1995-07-21 2000-08-11 Fujisawa Pharmaceutical Co Heterocyclic compounds having prostaglandin I2 agonism
US6018068A (en) 1995-07-26 2000-01-25 Ono Pharmaceutical Co., Ltd. Naphthyloxyacetic acid derivatives and drugs comprising the same as active ingredients
AUPP029197A0 (en) 1997-11-10 1997-12-04 Fujisawa Pharmaceutical Co., Ltd. Benzocycloheptene derivatives
AUPP109097A0 (en) 1997-12-22 1998-01-22 Fujisawa Pharmaceutical Co., Ltd. Napthalene derivatives

Also Published As

Publication number Publication date
NO316171B1 (no) 2003-12-22
ID25983A (id) 2000-11-16
TR199903310A2 (xx) 2000-10-23
CN1167670C (zh) 2004-09-22
HU9904659D0 (en) 2000-02-28
TWI221834B (en) 2004-10-11
NO996366L (no) 2000-06-26
ATE251125T1 (de) 2003-10-15
DE69911726D1 (de) 2003-11-06
AU6534099A (en) 2000-07-06
DE69911726T2 (de) 2004-07-29
HUP9904659A2 (hu) 2000-11-28
HRP990394A2 (en) 2000-08-31
AR029320A1 (es) 2003-06-25
NO996366D0 (no) 1999-12-21
PT1013639E (pt) 2004-02-27
CA2292921C (en) 2004-08-17
AU735640B2 (en) 2001-07-12
ES2207108T3 (es) 2004-05-16
UY25876A1 (es) 2001-07-31
US6335459B1 (en) 2002-01-01
NZ501891A (en) 2001-10-26
IL133578A0 (en) 2001-04-30
JP2000191523A (ja) 2000-07-11
SG90086A1 (en) 2002-07-23
BR9905974A (pt) 2000-09-12
YU69699A (sh) 2001-12-26
PE20001368A1 (es) 2000-12-14
JP3415085B2 (ja) 2003-06-09
KR100378335B1 (ko) 2003-03-29
EP1013639B1 (en) 2003-10-01
TR199903310A3 (tr) 2000-10-23
MA26713A1 (fr) 2004-12-20
EP1013639A1 (en) 2000-06-28
CN1266054A (zh) 2000-09-13
CA2292921A1 (en) 2000-06-23
IL133578A (en) 2004-07-25
RU2179969C2 (ru) 2002-02-27
HUP9904659A3 (en) 2000-12-28
KR20000048322A (ko) 2000-07-25
PL337419A1 (en) 2000-07-03

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