GB1079414A - Derivatives of acetic acid and a process for their preparation - Google Patents

Derivatives of acetic acid and a process for their preparation

Info

Publication number
GB1079414A
GB1079414A GB2762265A GB2762265A GB1079414A GB 1079414 A GB1079414 A GB 1079414A GB 2762265 A GB2762265 A GB 2762265A GB 2762265 A GB2762265 A GB 2762265A GB 1079414 A GB1079414 A GB 1079414A
Authority
GB
United Kingdom
Prior art keywords
ester
reacting
carbon atoms
alkali metal
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2762265A
Inventor
Donald Edwin Seymour
David John Drain
John Martin Scruton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith and Nephew PLC
TJ Smith and Nephew Ltd
Original Assignee
Smith and Nephew PLC
TJ Smith and Nephew Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith and Nephew PLC, TJ Smith and Nephew Ltd filed Critical Smith and Nephew PLC
Priority to GB2762265A priority Critical patent/GB1079414A/en
Publication of GB1079414A publication Critical patent/GB1079414A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups

Abstract

Novel compounds of formula <FORM:1079414/C2/1> in which each of R1, R2, R3 and R4 represents an alkyl group having 1-4 carbon atoms, an alkoxy group having 1-4 carbon atoms, a halogen atom, or a trifluoromethyl group, and each of n, m, p and q equals 0 or 1, are prepared by reacting an appropriately substituted salicylic acid with phosphorus oxychloride and phenol to give the phenyl ester, converting the ester to a salicyl-anilide by fusing the ester with an appropriately substituted aniline, preparing an alkali metal derivative of this compound and reacting the alkali metal derivative with ethyl chloracetate, and hydrolysing the ethyl 2-(N-phenyl)-carbamoyl-phenoxyacetate formed.
GB2762265A 1965-06-30 1965-06-30 Derivatives of acetic acid and a process for their preparation Expired GB1079414A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2762265A GB1079414A (en) 1965-06-30 1965-06-30 Derivatives of acetic acid and a process for their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2762265A GB1079414A (en) 1965-06-30 1965-06-30 Derivatives of acetic acid and a process for their preparation

Publications (1)

Publication Number Publication Date
GB1079414A true GB1079414A (en) 1967-08-16

Family

ID=10262600

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2762265A Expired GB1079414A (en) 1965-06-30 1965-06-30 Derivatives of acetic acid and a process for their preparation

Country Status (1)

Country Link
GB (1) GB1079414A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986005779A1 (en) * 1985-04-03 1986-10-09 Yamanouchi Pharmaceutical Co., Ltd. Phenylene derivatives
EP0558062A2 (en) * 1992-02-28 1993-09-01 Ono Pharmaceutical Co., Ltd. Phenoxyacetic acid derivatives and pharmaceutical compositions containing them
US6335459B1 (en) 1998-12-23 2002-01-01 Syntex (U.S.A.) Llc Aryl carboxylic acid and aryl tetrazole derivatives as IP receptor modulators

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986005779A1 (en) * 1985-04-03 1986-10-09 Yamanouchi Pharmaceutical Co., Ltd. Phenylene derivatives
EP0558062A2 (en) * 1992-02-28 1993-09-01 Ono Pharmaceutical Co., Ltd. Phenoxyacetic acid derivatives and pharmaceutical compositions containing them
EP0558062A3 (en) * 1992-02-28 1994-01-12 Ono Pharmaceutical Co
US5378716A (en) * 1992-02-28 1995-01-03 Ono Pharmaceutical Co., Ltd. Pyrazol-1-yl phenoxyacetic acid compounds which have useful pharmaceutical utility
US5935985A (en) * 1992-02-28 1999-08-10 Ono Pharmaceutical Co., Ltd. Phenoxyacetic acid derivatives
US6335459B1 (en) 1998-12-23 2002-01-01 Syntex (U.S.A.) Llc Aryl carboxylic acid and aryl tetrazole derivatives as IP receptor modulators

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