NO995160L - Fremgangsmåte for fremstilling av overflate metall trikarbonylforbindelser og deres bruk i merking av biologisk aktive substrater - Google Patents
Fremgangsmåte for fremstilling av overflate metall trikarbonylforbindelser og deres bruk i merking av biologisk aktive substraterInfo
- Publication number
- NO995160L NO995160L NO995160A NO995160A NO995160L NO 995160 L NO995160 L NO 995160L NO 995160 A NO995160 A NO 995160A NO 995160 A NO995160 A NO 995160A NO 995160 L NO995160 L NO 995160L
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- compound
- water
- biologically active
- surface metal
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 5
- 238000002360 preparation method Methods 0.000 title abstract 4
- 238000002372 labelling Methods 0.000 title abstract 3
- 229910052751 metal Inorganic materials 0.000 title abstract 3
- 239000002184 metal Substances 0.000 title abstract 3
- 239000000758 substrate Substances 0.000 title abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 3
- UGFAIRIUMAVXCW-UHFFFAOYSA-N Carbon monoxide Chemical compound [O+]#[C-] UGFAIRIUMAVXCW-UHFFFAOYSA-N 0.000 abstract 2
- 229910002091 carbon monoxide Inorganic materials 0.000 abstract 2
- 239000003638 chemical reducing agent Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
- 235000000346 sugar Nutrition 0.000 abstract 1
- 150000008163 sugars Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0476—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from monodendate ligands, e.g. sestamibi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
- C01G45/00—Compounds of manganese
- C01G45/04—Carbonyls
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
- C01G99/00—Subject matter not provided for in other groups of this subclass
- C01G99/006—Compounds containing a metal not provided for elsewhere in this subclass, with or without oxygen or hydrogen, and containing two or more other elements
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/004—Acyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
- C07F13/005—Compounds without a metal-carbon linkage
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
- C01P2006/00—Physical properties of inorganic compounds
- C01P2006/88—Isotope composition differing from the natural occurrence
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Steroid Compounds (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97201232A EP0879606A1 (en) | 1997-04-25 | 1997-04-25 | Method for the preparation of facial metal tricarbonyl compounds and their use in the labelling of biologically active substrates |
| PCT/US1998/007979 WO1998048848A1 (en) | 1997-04-25 | 1998-04-21 | Method for the preparation of facial metal tricarbonyl compounds and their use in the labelling of biologically active substrates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO995160D0 NO995160D0 (no) | 1999-10-22 |
| NO995160L true NO995160L (no) | 1999-12-13 |
Family
ID=8228251
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO995160A NO995160L (no) | 1997-04-25 | 1999-10-22 | Fremgangsmåte for fremstilling av overflate metall trikarbonylforbindelser og deres bruk i merking av biologisk aktive substrater |
Country Status (18)
| Country | Link |
|---|---|
| EP (2) | EP0879606A1 (es) |
| JP (1) | JP4357597B2 (es) |
| KR (1) | KR100579168B1 (es) |
| AT (1) | ATE211924T1 (es) |
| AU (1) | AU748213B2 (es) |
| BR (1) | BR9809409B1 (es) |
| CA (1) | CA2282563C (es) |
| CZ (1) | CZ295214B6 (es) |
| DE (1) | DE69803205T2 (es) |
| DK (1) | DK1019095T3 (es) |
| ES (1) | ES2168751T3 (es) |
| HU (1) | HU225487B1 (es) |
| IL (1) | IL131658A (es) |
| NO (1) | NO995160L (es) |
| NZ (1) | NZ337303A (es) |
| PL (1) | PL189514B1 (es) |
| PT (1) | PT1019095E (es) |
| WO (1) | WO1998048848A1 (es) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19860289C2 (de) * | 1998-12-21 | 2003-11-13 | Schering Ag | Neue Chelatoren sowie deren Tricarbonyl-Komplexe mit Technetium und Rhenium |
| EP1021074B1 (en) | 1999-01-15 | 2012-06-20 | The Boeing Company | Solid state flight deck panels and components thereof |
| US6844425B1 (en) | 1999-02-24 | 2005-01-18 | Mallinckrodt Inc. | Combination of intercalating organometallic complexes and tumor seeking biomolecules for DNA cleavage and radiotherapy |
| DK1154798T3 (da) * | 1999-02-24 | 2006-08-28 | Univ Zuerich | Molekyler til behandling og diagnose af tumorer |
| US6926883B1 (en) * | 1999-06-29 | 2005-08-09 | Mallinckrodt Inc | Group (VII) transition-metal complexes with multidentate aminopolycarboxylate ligands and a kit for producing them |
| ES2223559T3 (es) * | 1999-06-29 | 2005-03-01 | Mallinckrodt Inc. | Complejos de metales de transicion del grupo (vii) con ligandos aminopolicarboxilato multidentados y kit para producirlos. |
| AUPQ262499A0 (en) * | 1999-09-02 | 1999-09-23 | University Of Queensland, The | Novel iron chelators |
| DK1218385T3 (da) * | 1999-10-05 | 2009-04-27 | Mallinckrodt Inc | Carbonmonoxidkilde til fremstilling af overgangsmetalcarbonylkomplekser |
| US6359119B1 (en) * | 2000-05-24 | 2002-03-19 | Mallinckrodt Inc. | Formulation of Tc and Re carbonyl complexes using stannous ion as the reductant for pertechnetate and perrhenate |
| IL153218A0 (en) * | 2000-06-02 | 2003-07-06 | Univ Texas | Ethylenedicysteine (ec) -drug conjugates |
| CN1136921C (zh) * | 2001-04-27 | 2004-02-04 | 北京师范大学 | 一种心肌显像剂及其制备方法 |
| GB0111872D0 (en) | 2001-05-15 | 2001-07-04 | Northwick Park Inst For Medica | Therapeutic agents and methods |
| BR0307420A (pt) | 2002-02-04 | 2004-12-21 | Werner Haas | Compostos, composições farmacêuticas e métodos para impedir e/ou tratar doença em mamìfero |
| KR100445971B1 (ko) * | 2002-04-15 | 2004-08-25 | 한국원자력연구소 | 수소화붕소 교환수지를 이용한 테크네튬 또는 레늄의표지방법 |
| PL375530A1 (en) * | 2002-09-03 | 2005-11-28 | University Of Zurich | Preparation of m(co)3-complexes by solid phase techniques via metal assisted cleavage from the solid support |
| GB2395432B (en) * | 2002-11-20 | 2005-09-14 | Northwick Park Inst For Medica | Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs |
| US7682601B2 (en) | 2003-04-15 | 2010-03-23 | Mallinckrodt Inc. | Bifunctional tridentate pyrazolyl containing ligands for re and tc tricarbonyl complexes |
| CA2522326C (en) | 2003-04-15 | 2012-09-18 | Mallinckrodt Llc | Bifunctional tridentate pyrazolyl containing ligands for re, tc and mn tricarbonyl complexes |
| DE602004024879D1 (de) * | 2003-04-29 | 2010-02-11 | Univ Zuerich | AN EINEM BIOMOLEKÜL GEBUNDENEN N epsilon- UND/ODER N alpha DERIVATISIERTEM UND ORGANISCH-GESCHÜTZTEM L-HISTIDIN ZUR HOCH-EFFIZIENTER MARKIERUNG MIT (M(H2O)3(CO)3)+ MITTELS FAC KOORDINIERUNG |
| AU2005282160A1 (en) * | 2004-09-07 | 2006-03-16 | Triumf, Operating As A Joint Venture By The Governors Of The University Of Alberta, The University Of British Columbia, Carleton University, Simon Fraser University, The University Of Toronto And The University Of Victoria | Synthesis of radiolabeled sugar metal complexes |
| JP2008037752A (ja) * | 2004-11-19 | 2008-02-21 | Nihon Medi Physics Co Ltd | 新規放射性テクネチウム−ビスホスフィノアミン錯体および該錯体を含む放射性画像診断剤 |
| KR100650506B1 (ko) * | 2005-12-16 | 2006-11-30 | 한국원자력연구소 | 방사성 의약품용 레늄-트리카보닐 착물 및 그 전구체의제조방법 |
| US10925977B2 (en) | 2006-10-05 | 2021-02-23 | Ceil>Point, LLC | Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications |
| GB0623482D0 (en) | 2006-11-24 | 2007-01-03 | Mallinckrodt Inc | Technetium-99m (l) tricarbonyl complexes with tridentate chelators for myocardium imaging |
| DE102010014411A1 (de) | 2010-04-08 | 2011-10-13 | Friedrich-Schiller-Universität Jena | Kohlenmonoxid und Eisen freisetzende Moleküle, deren Verwendung und Verfahren zu deren Herstellung |
| DE102010014412A1 (de) | 2010-04-08 | 2012-04-19 | Friedrich-Schiller-Universität Jena | Verwendung von zweikernigen Eisenkomplexen mit schwefelhaltigen Liganden als pharmakologische Wirkstoffe |
| WO2012145520A2 (en) | 2011-04-19 | 2012-10-26 | Alfama, Inc. | Carbon monoxide releasing molecules and uses thereof |
| EP2734235B1 (en) | 2011-07-21 | 2017-03-22 | Alfama, Inc. | Ruthenium carbon monoxide releasing molecules and uses thereof |
| DE102012004132A1 (de) | 2012-02-29 | 2013-08-29 | Friedrich-Schiller-Universität Jena | Kohlenstoffmonoxid freisetzende Materialien und deren Verwendung |
| KR101200049B1 (ko) * | 2012-05-14 | 2012-11-13 | 한국원자력연구원 | 테크네튬-99엠 트리카보닐 표지 글리신 단량체 또는 올리고머 활용 생리활성분자를 이용한 프로브의 제조방법 및 이를 포함하는 영상제 조성물 |
| DE102014008537A1 (de) | 2014-06-04 | 2015-12-17 | Friedrich-Schiller-Universität Jena | Wasserlösliche manganbasierte Kohlenstoffmonoxid freisetzende Moleküle, deren Verwendung und Verfahren zu deren Herstellung |
| RU2708076C1 (ru) * | 2019-09-10 | 2019-12-04 | федеральное государственное автономное образовательное учреждение высшего образования «Национальный исследовательский Томский политехнический университет» | Способ получения комплекса технеция-99м с производным октреотида для диагностики нейроэндокринных опухолей |
| KR102269315B1 (ko) | 2019-10-24 | 2021-06-24 | 서울대학교산학협력단 | 전립선 암의 영상 또는 치료를 위한 동위원소 표지 화합물 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2533570B1 (fr) * | 1982-09-23 | 1985-07-12 | Centre Nat Rech Scient | Complexes organometalliques d'oestrogenes et leur application au dosage des recepteurs hormonaux |
-
1997
- 1997-04-25 EP EP97201232A patent/EP0879606A1/en not_active Withdrawn
-
1998
- 1998-04-21 HU HU0003255A patent/HU225487B1/hu unknown
- 1998-04-21 NZ NZ337303A patent/NZ337303A/xx not_active IP Right Cessation
- 1998-04-21 EP EP98918501A patent/EP1019095B1/en not_active Expired - Lifetime
- 1998-04-21 CA CA002282563A patent/CA2282563C/en not_active Expired - Lifetime
- 1998-04-21 DK DK98918501T patent/DK1019095T3/da active
- 1998-04-21 DE DE69803205T patent/DE69803205T2/de not_active Expired - Lifetime
- 1998-04-21 WO PCT/US1998/007979 patent/WO1998048848A1/en not_active Ceased
- 1998-04-21 KR KR1019997009902A patent/KR100579168B1/ko not_active Expired - Lifetime
- 1998-04-21 AT AT98918501T patent/ATE211924T1/de active
- 1998-04-21 AU AU71413/98A patent/AU748213B2/en not_active Expired
- 1998-04-21 CZ CZ19993751A patent/CZ295214B6/cs not_active IP Right Cessation
- 1998-04-21 BR BRPI9809409-2A patent/BR9809409B1/pt not_active IP Right Cessation
- 1998-04-21 PL PL98336382A patent/PL189514B1/pl unknown
- 1998-04-21 IL IL13165898A patent/IL131658A/en not_active IP Right Cessation
- 1998-04-21 JP JP54639198A patent/JP4357597B2/ja not_active Expired - Lifetime
- 1998-04-21 ES ES98918501T patent/ES2168751T3/es not_active Expired - Lifetime
- 1998-04-21 PT PT98918501T patent/PT1019095E/pt unknown
-
1999
- 1999-10-22 NO NO995160A patent/NO995160L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP4357597B2 (ja) | 2009-11-04 |
| EP0879606A1 (en) | 1998-11-25 |
| WO1998048848A1 (en) | 1998-11-05 |
| JP2002512616A (ja) | 2002-04-23 |
| CA2282563C (en) | 2007-12-04 |
| DK1019095T3 (da) | 2002-05-06 |
| PT1019095E (pt) | 2002-07-31 |
| EP1019095A1 (en) | 2000-07-19 |
| HUP0003255A3 (en) | 2003-06-30 |
| HUP0003255A2 (hu) | 2001-02-28 |
| DE69803205T2 (de) | 2002-09-19 |
| CZ295214B6 (cs) | 2005-06-15 |
| IL131658A0 (en) | 2001-01-28 |
| ATE211924T1 (de) | 2002-02-15 |
| DE69803205D1 (de) | 2002-02-21 |
| EP1019095B1 (en) | 2002-01-16 |
| BR9809409B1 (pt) | 2008-11-18 |
| NZ337303A (en) | 2000-12-22 |
| KR20010020298A (ko) | 2001-03-15 |
| CA2282563A1 (en) | 1998-11-05 |
| HU225487B1 (en) | 2006-12-28 |
| PL336382A1 (en) | 2000-06-19 |
| ES2168751T3 (es) | 2002-06-16 |
| PL189514B1 (pl) | 2005-08-31 |
| AU7141398A (en) | 1998-11-24 |
| BR9809409A (pt) | 2000-06-13 |
| AU748213B2 (en) | 2002-05-30 |
| IL131658A (en) | 2004-12-15 |
| KR100579168B1 (ko) | 2006-05-12 |
| CZ9903751A3 (en) | 2001-05-16 |
| NO995160D0 (no) | 1999-10-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO995160D0 (no) | Fremgangsmåte for fremstilling av overflate metall trikarbonylforbindelser og deres bruk i merking av biologisk aktive substrater | |
| Chakravarty et al. | Plasmin-activated prodrugs for cancer chemotherapy. 1. Synthesis and biological activity of peptidylacivicin and peptidylphenylenediamine mustard | |
| Chen et al. | Native chemical ligation at valine: a contribution to peptide and glycopeptide synthesis | |
| US5183653A (en) | Boronic acid adducts of metal dioxime complexes useful in labelling proteins and other amine-containing compounds | |
| US5180816A (en) | One vial method for labeling protein/linker conjugates with technetium-99M | |
| EP0420934B1 (en) | Bifunctional coupling agents and radionuclide labeled compositions prepared therefrom | |
| JPH07103159B2 (ja) | 放射性核種金属キレート | |
| KR20090096597A (ko) | [ｆ-１８]-표지된 ｌ-글루탐산, [ｆ-１８]-표지된 ｌ-글루타민, 이들의 유도체 및 이들의 용도 및 이들의 제조 방법 | |
| JPS58116443A (ja) | 新規ペプチドおよびその製法 | |
| Bentley et al. | Qualitative determination of N-terminal amino acids of peptides and proteins with cobalt (III) chelates | |
| Zarezin et al. | Diazocarbonyl derivatives of amino acids: unique chiral building blocks for the synthesis of biologically active compounds | |
| CA2019035C (en) | Stabilized radiopharmaceutical compositions | |
| AU722595B2 (en) | Urethane mediated, GST specific molecular release systems | |
| US5144043A (en) | Cleavable bifunctional coupling agents | |
| Sauvé et al. | Carboxyl-modified amino acids and peptides: II) A convenient route for the synthesis of difunctionalized enamines from thioamides via thioiminium salts | |
| Okarvi et al. | Comparison of the labelling characteristics of mercaptoacetyltriglycine (MAG3) with different S‐protective groups | |
| ATE82130T1 (de) | Verfahren zum affinitaetschromatografischen reinigen von faktor xiii. | |
| Hofmann et al. | Radioactive probes for adrenocorticotropic hormone receptors | |
| KR100755935B1 (ko) | 히스티딘 유도체 및 이를 이용한 금속 트리카보닐 착화물,이들의 제조방법 및 이들을 포함하는 조영제 | |
| JPH02503006A (ja) | 医薬作用を有するプリン誘導体 | |
| Okarvi et al. | Synthesis, radiolabelling characteristics and biological evaluation of the derivatives of mercaptoacetyltriglycine | |
| SANO | Chemical synthesis of the cytochrome c molecule | |
| Wunderlin et al. | Melanotropin Receptors I. Synthesis and Biological Activity of Nα‐(5‐Bromovaleryl)‐Nα‐deacetyl‐α‐melanotropin | |
| JP2680080B2 (ja) | 新規カルシトニン誘導体 | |
| Krchňák et al. | [1-β-Mercaptopropionic acid, 8-α, β-diaminopropionic acid] vasopressin and [1-β-mercaptopropionic acid, 8-D-α, β-diaminopropionic acid] vasopressin. Two lysine-vasopressin analogs with considerable antidiuretic effect |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |