NO991902L - Substituerte aminoalkanfosfonsyrer - Google Patents

Substituerte aminoalkanfosfonsyrer

Info

Publication number
NO991902L
NO991902L NO991902A NO991902A NO991902L NO 991902 L NO991902 L NO 991902L NO 991902 A NO991902 A NO 991902A NO 991902 A NO991902 A NO 991902A NO 991902 L NO991902 L NO 991902L
Authority
NO
Norway
Prior art keywords
pct
aliphatic
araliphatic
date apr
phosphonic acids
Prior art date
Application number
NO991902A
Other languages
English (en)
Norwegian (no)
Other versions
NO991902D0 (no
Inventor
Pierre Acklin
Hans Allgeier
Yves Auberson
Silvio Ofner
Siem Jacob Veenstra
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO991902D0 publication Critical patent/NO991902D0/no
Publication of NO991902L publication Critical patent/NO991902L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509Six-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509Six-membered rings
    • C07F9/650952Six-membered rings having the nitrogen atoms in the positions 1 and 4
    • C07F9/650994Six-membered rings having the nitrogen atoms in the positions 1 and 4 condensed with carbocyclic rings or carbocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
NO991902A 1996-10-24 1999-04-21 Substituerte aminoalkanfosfonsyrer NO991902L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH262196 1996-10-24
PCT/EP1997/005843 WO1998017672A1 (de) 1996-10-24 1997-10-22 Substituierte aminoalkanphosphonsäuren

Publications (2)

Publication Number Publication Date
NO991902D0 NO991902D0 (no) 1999-04-21
NO991902L true NO991902L (no) 1999-06-21

Family

ID=4237878

Family Applications (1)

Application Number Title Priority Date Filing Date
NO991902A NO991902L (no) 1996-10-24 1999-04-21 Substituerte aminoalkanfosfonsyrer

Country Status (23)

Country Link
US (1) US6117873A (ru)
EP (1) EP0934326B1 (ru)
JP (1) JP3908790B2 (ru)
KR (1) KR20000052747A (ru)
CN (1) CN1092202C (ru)
AT (1) ATE325128T1 (ru)
AU (1) AU5188598A (ru)
BR (1) BR9713489A (ru)
CA (1) CA2269807C (ru)
CZ (1) CZ141399A3 (ru)
DE (1) DE59712642D1 (ru)
ES (1) ES2264171T3 (ru)
HU (1) HUP0000383A3 (ru)
ID (1) ID21927A (ru)
IL (1) IL129394A (ru)
NO (1) NO991902L (ru)
NZ (1) NZ334891A (ru)
PL (1) PL192286B1 (ru)
PT (1) PT934326E (ru)
RU (1) RU2181362C2 (ru)
SK (1) SK282548B6 (ru)
TR (1) TR199900897T2 (ru)
WO (1) WO1998017672A1 (ru)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2645199A (en) * 1998-11-18 2000-06-05 Viktor Veniaminovich Tets Dialkyl-1-aryl-1-(2,4-dioxo-5-amino-1,3-pyrimidin-5-yl)methy lphosphonates
US7205404B1 (en) 1999-03-05 2007-04-17 Metabasis Therapeutics, Inc. Phosphorus-containing prodrugs
US20030114421A1 (en) * 2000-09-27 2003-06-19 Phan Hieu Trung Alpha-substituted beta-aminoethyl phosphonate derivatives
CN1489596A (zh) 2000-09-27 2004-04-14 �Ʒ� α-取代的β-氨基乙基膦酸酯类化合物
GB0025849D0 (en) 2000-10-23 2000-12-06 Smithkline Beecham Plc Novel compounds
US6492517B1 (en) 2001-07-19 2002-12-10 Air Products And Chemicals, Inc. Method for preparing halomethyl heterocyclic compounds
TW200403066A (en) * 2002-04-30 2004-03-01 Novartis Ag New uses of substituted aminoalkanephosphonic acids
GB0307860D0 (en) * 2003-04-04 2003-05-14 Novartis Ag Organic compounds
GB0310868D0 (en) * 2003-05-12 2003-06-18 Novartis Ag Organic compounds
GB0324542D0 (en) * 2003-10-21 2003-11-26 Novartis Ag Organic compounds
GB0324541D0 (en) * 2003-10-21 2003-11-26 Novartis Ag Organic compounds
GB0325173D0 (en) * 2003-10-28 2003-12-03 Novartis Ag Organic compounds
GB0325172D0 (en) * 2003-10-28 2003-12-03 Novartis Ag Organic compounds
GB0325175D0 (en) * 2003-10-28 2003-12-03 Novartis Ag Organic compounds
GB0325390D0 (en) * 2003-10-30 2003-12-03 Novartis Ag Organic compounds
CA2546601A1 (en) * 2003-11-19 2005-06-09 Metabasis Therapeutics, Inc. Novel phosphorus-containing thyromimetics
GB0405034D0 (en) * 2004-03-05 2004-04-07 Novartis Ag Organic compounds
ME01224B (me) * 2005-04-04 2013-06-20 Eisai R&D Man Co Ltd Jedinjenja dihidropiridina za liječenje neurodegenerativnih bolesti i demencije
GB0507298D0 (en) 2005-04-11 2005-05-18 Novartis Ag Organic compounds
AU2006249348B2 (en) * 2005-05-26 2012-05-24 Metabasis Therapeutics, Inc. Novel phosphinic acid-containing thyromimetics
EP1898926A2 (en) 2005-05-26 2008-03-19 Metabasis Therapeutics, Inc. Thyromimetics for the treatment of fatty liver diseases
US20080108603A1 (en) * 2006-10-19 2008-05-08 Eisenach James C Combination therapy for the treatment of pain
US20080108622A1 (en) * 2006-10-19 2008-05-08 Eisenach James C Combination therapy for the treatment of pain
GB0708507D0 (en) * 2007-05-02 2007-06-13 Queen Mary & Westfield College Substituted phosphonates and their use
WO2009104147A2 (en) 2008-02-20 2009-08-27 Actelion Pharmaceuticals Ltd Azatricyclic antibiotic compounds
CA2733390A1 (en) * 2008-08-01 2010-02-04 Bioxiness Pharmaceuticals, Inc. Methionine analogs and methods of using same
DK2344495T3 (en) 2008-10-07 2015-02-02 Actelion Pharmaceuticals Ltd TRICYCLIC OXAZOLIDINON ANTIBIOTIC COMPOUNDS
US8193372B2 (en) * 2009-03-04 2012-06-05 Idenix Pharmaceuticals, Inc. Phosphothiophene and phosphothiazole HCV polymerase inhibitors
US10449210B2 (en) 2014-02-13 2019-10-22 Ligand Pharmaceuticals Inc. Prodrug compounds and their uses
JP2017520545A (ja) 2014-07-02 2017-07-27 リガンド・ファーマシューティカルズ・インコーポレイテッド プロドラッグ化合物およびそれらの使用
CA3044059A1 (en) 2016-11-21 2018-05-24 Viking Therapeutics, Inc. Method of treating glycogen storage disease
EA201992703A1 (ru) 2017-06-05 2020-04-15 Вайкинг Терапьютикс, Инк. Композиции для лечения фиброза
CA3094167A1 (en) 2018-03-22 2019-09-26 Viking Therapeutics, Inc. Crystalline forms and methods of producing crystalline forms of a compound
CN114409890A (zh) * 2022-02-28 2022-04-29 中国科学院长春应用化学研究所 一种氨基功能化的聚乙二醇衍生物及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO179551C (no) * 1987-11-10 1996-10-30 Novo Nordisk As Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser
DK69790D0 (da) * 1990-03-16 1990-03-16 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling af anvendelse
AU656154B2 (en) * 1990-11-06 1995-01-27 Astellas Pharma Inc. Fused pyrazine derivative
US5118675A (en) * 1991-02-15 1992-06-02 American Home Products Corporation Quinoxaline phosphono-amino acids
US5480883A (en) * 1991-05-10 1996-01-02 Rhone-Poulenc Rorer Pharmaceuticals Inc. Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
PT647137E (pt) * 1992-06-22 2008-11-24 Univ California Antagonistas dos receptores da glicina e a sua utilização
IL109397A0 (en) * 1993-04-28 1994-07-31 Schering Ag Quinoxalinedione derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
CZ5398A3 (cs) * 1995-07-10 1998-06-17 Novartis Ag Chinoxalin- a chinoxalinylalkanfosfonové kyseliny, způsob jejich přípravy, farmaceutický prostředek, který je obsahuje, a jejich použití
MY132385A (en) * 1995-08-31 2007-10-31 Novartis Ag 2,3-dioxo-1,2,3,4-tetrahydro-quinoxalinyl derivatives

Also Published As

Publication number Publication date
ES2264171T3 (es) 2006-12-16
IL129394A (en) 2002-05-23
AU5188598A (en) 1998-05-15
CA2269807A1 (en) 1998-04-30
WO1998017672A1 (de) 1998-04-30
KR20000052747A (ko) 2000-08-25
JP2001502681A (ja) 2001-02-27
PT934326E (pt) 2006-08-31
NO991902D0 (no) 1999-04-21
BR9713489A (pt) 2000-02-29
IL129394A0 (en) 2000-02-17
HUP0000383A3 (en) 2003-01-28
DE59712642D1 (de) 2006-06-08
CN1234037A (zh) 1999-11-03
NZ334891A (en) 2001-04-27
RU2181362C2 (ru) 2002-04-20
ID21927A (id) 1999-08-12
PL192286B1 (pl) 2006-09-29
PL332775A1 (en) 1999-10-11
US6117873A (en) 2000-09-12
ATE325128T1 (de) 2006-06-15
CZ141399A3 (cs) 1999-07-14
CA2269807C (en) 2007-04-10
JP3908790B2 (ja) 2007-04-25
TR199900897T2 (xx) 1999-07-21
EP0934326A1 (de) 1999-08-11
EP0934326B1 (de) 2006-05-03
SK282548B6 (sk) 2002-10-08
CN1092202C (zh) 2002-10-09
HUP0000383A2 (hu) 2001-05-28
SK52399A3 (en) 2000-04-10

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