NO991761D0 - Nye piperidin-kotokarbonsyre-derivater, deres fremstilling og anvendelse - Google Patents

Nye piperidin-kotokarbonsyre-derivater, deres fremstilling og anvendelse

Info

Publication number
NO991761D0
NO991761D0 NO991761A NO991761A NO991761D0 NO 991761 D0 NO991761 D0 NO 991761D0 NO 991761 A NO991761 A NO 991761A NO 991761 A NO991761 A NO 991761A NO 991761 D0 NO991761 D0 NO 991761D0
Authority
NO
Norway
Prior art keywords
cotocarboxylic
preparation
acid derivatives
new piperidine
piperidine
Prior art date
Application number
NO991761A
Other languages
English (en)
Norwegian (no)
Other versions
NO991761L (no
Inventor
Wilfried Lubisch
Ller Achim M
J Rgen Delzer
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of NO991761L publication Critical patent/NO991761L/no
Publication of NO991761D0 publication Critical patent/NO991761D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO991761A 1996-10-15 1999-04-14 Nye piperidin-kotokarbonsyre-derivater, deres fremstilling og anvendelse NO991761D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19642591A DE19642591A1 (de) 1996-10-15 1996-10-15 Neue Piperidin-Ketocarbonsäure-Derivate, deren Herstellung und Anwendung
PCT/EP1997/005202 WO1998016512A1 (de) 1996-10-15 1997-09-23 Neue piperidin-ketocarbonsäure-derivate, deren herstellung und anwendung

Publications (2)

Publication Number Publication Date
NO991761L NO991761L (no) 1999-04-14
NO991761D0 true NO991761D0 (no) 1999-04-14

Family

ID=7808858

Family Applications (1)

Application Number Title Priority Date Filing Date
NO991761A NO991761D0 (no) 1996-10-15 1999-04-14 Nye piperidin-kotokarbonsyre-derivater, deres fremstilling og anvendelse

Country Status (24)

Country Link
US (1) US6380220B1 (ru)
EP (1) EP0934273A1 (ru)
JP (1) JP2001501955A (ru)
KR (1) KR20000049130A (ru)
CN (1) CN1239950A (ru)
AR (1) AR009379A1 (ru)
AU (1) AU736754B2 (ru)
BG (1) BG103338A (ru)
BR (1) BR9711908A (ru)
CA (1) CA2268917A1 (ru)
CO (1) CO4930264A1 (ru)
CZ (1) CZ126899A3 (ru)
DE (1) DE19642591A1 (ru)
HR (1) HRP970549A2 (ru)
HU (1) HUP9904104A3 (ru)
IL (1) IL129089A0 (ru)
NO (1) NO991761D0 (ru)
NZ (1) NZ334979A (ru)
PL (1) PL332720A1 (ru)
RU (1) RU2189974C2 (ru)
SK (1) SK38599A3 (ru)
TR (1) TR199900819T2 (ru)
WO (1) WO1998016512A1 (ru)
ZA (1) ZA979175B (ru)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19817459A1 (de) 1998-04-20 1999-10-21 Basf Ag Neue heterozyklische substituierte Amide, Herstellung und Anwendung
AU3818799A (en) * 1998-04-20 1999-11-08 Basf Aktiengesellschaft Novel heterocyclically substituted amides with cysteine protease-inhibiting effect
JP4782924B2 (ja) * 1998-04-20 2011-09-28 アボット ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト 新規の置換アミド、それらの製造および使用
CN1297441A (zh) 1998-04-20 2001-05-30 Basf公司 用作为钙蛋白酶抑制剂的杂环取代酰胺
US6117870A (en) * 1998-11-12 2000-09-12 Fujirebio Kabushiki Kaisha Cyclic amide derivatives
AU6936500A (en) * 1999-08-24 2001-03-19 Regents Of The University Of California, The Non-quinoline inhibitors of malaria parasites
CZ20011872A3 (cs) 1999-09-29 2002-03-13 Ortho-Mcneil Pharmaceutical, Inc. Isonipekotamidy pro léčbu onemocnění zprostředkovaných integriny
WO2002002546A1 (fr) 2000-06-30 2002-01-10 Seikagaku Corporation Amides d'acide carboxylique, azides et amino-alcools et procedes de preparation de $g(a)-ceto amides a l'aide de ces derniers
DE10114762A1 (de) * 2001-03-26 2002-10-02 Knoll Gmbh Verwendung von Cysteinprotease-Inhibitoren
JP2004529918A (ja) 2001-04-09 2004-09-30 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド インテグリンに由来する疾患の治療のためのキナゾリンおよびキナゾリン類似化合物
JP4617449B2 (ja) 2002-07-11 2011-01-26 ヴィキュロン ファーマシューティカルズ インコーポレイテッド 抗菌活性を有するn−ヒドロキシアミド誘導体
WO2005016883A2 (en) * 2003-08-14 2005-02-24 Icos Corporation Acrylamide derivatives as vla-1 integrin antagonists and uses thereof
JP5295976B2 (ja) 2006-12-29 2013-09-18 アボット ゲーエムベーハー ウント カンパニー カーゲー カルボキサミド化合物およびカルパイン阻害剤としてのこれらの使用
TWI453019B (zh) * 2007-12-28 2014-09-21 Abbvie Deutschland 甲醯胺化合物
TWI519530B (zh) 2009-02-20 2016-02-01 艾伯維德國有限及兩合公司 羰醯胺化合物及其作為鈣蛋白酶(calpain)抑制劑之用途
US8236798B2 (en) 2009-05-07 2012-08-07 Abbott Gmbh & Co. Kg Carboxamide compounds and their use as calpain inhibitors
US8598211B2 (en) 2009-12-22 2013-12-03 Abbvie Inc. Carboxamide compounds and their use as calpain inhibitors IV
US9051304B2 (en) 2009-12-22 2015-06-09 AbbVie Deutschland GmbH & Co. KG Carboxamide compounds and their use as calpain inhibitors V
WO2012076639A1 (en) 2010-12-09 2012-06-14 Abbott Gmbh & Co. Kg Carboxamide compounds and their use as calpain inhibitors v
RU2014144285A (ru) 2012-04-03 2016-05-27 Эббви Дойчланд Гмбх Унд Ко. Кг Карбоксамидные соединения и их применение в качестве ингибиторов кальпаина v
EP3426674A4 (en) 2016-03-09 2019-08-14 Blade Therapeutics, Inc. CYCLIC KETO AMID COMPOUNDS AS CALPAIN MODULATORS AND METHOD FOR THE PRODUCTION AND USE THEREOF
AU2017292646A1 (en) 2016-07-05 2019-02-07 Blade Therapeutics, Inc. Calpain modulators and therapeutic uses thereof
CA3038331A1 (en) 2016-09-28 2018-04-05 Blade Therapeutics, Inc. Calpain modulators and therapeutic uses thereof
JP7293129B2 (ja) 2017-06-01 2023-06-19 エーザイ・アール・アンド・ディー・マネジメント株式会社 Pde9阻害剤を含む医薬組成物
CA3061884A1 (en) 2017-06-01 2019-10-29 Eisai R&D Management Co., Ltd. Lewy body disease therapeutic agent containing pyrazoloquinoline derivative
AU2019242387A1 (en) * 2018-03-28 2020-11-19 Blade Therapeutics, Inc. Calpain modulators and therapeutic uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992011850A2 (en) * 1990-12-28 1992-07-23 Cortex Pharmaceuticals, Inc. Use of calpain inhibitors in the inhibition and treatment of neurodegeneration
WO1992012140A1 (en) * 1990-12-28 1992-07-23 Georgia Tech Research Corporation Peptides ketoamides, ketoacids, and ketoesters
CA2071621C (en) 1991-06-19 1996-08-06 Ahihiko Hosoda Aldehyde derivatives
JPH09500087A (ja) * 1992-06-24 1997-01-07 コーテックス ファーマシューティカルズ インコーポレイテッド カルパイン活性の増大に関連した健康障害の抑制及び処置におけるカルパイン阻害剤の使用法
US5541290A (en) * 1993-06-24 1996-07-30 Harbeson; Scott L. Optically pure calpain inhibitor compounds

Also Published As

Publication number Publication date
JP2001501955A (ja) 2001-02-13
HRP970549A2 (en) 1998-08-31
AR009379A1 (es) 2000-04-12
CO4930264A1 (es) 2000-06-27
NZ334979A (en) 2001-02-23
AU4777097A (en) 1998-05-11
PL332720A1 (en) 1999-10-11
CZ126899A3 (cs) 1999-07-14
CA2268917A1 (en) 1998-04-23
BG103338A (bg) 2000-01-31
NO991761L (no) 1999-04-14
HUP9904104A2 (hu) 2000-05-28
ZA979175B (en) 1999-04-14
RU2189974C2 (ru) 2002-09-27
IL129089A0 (en) 2000-02-17
US6380220B1 (en) 2002-04-30
DE19642591A1 (de) 1998-04-16
KR20000049130A (ko) 2000-07-25
CN1239950A (zh) 1999-12-29
SK38599A3 (en) 2000-04-10
TR199900819T2 (xx) 1999-06-21
HUP9904104A3 (en) 2001-01-29
EP0934273A1 (de) 1999-08-11
AU736754B2 (en) 2001-08-02
WO1998016512A1 (de) 1998-04-23
BR9711908A (pt) 1999-08-24

Similar Documents

Publication Publication Date Title
NO991761D0 (no) Nye piperidin-kotokarbonsyre-derivater, deres fremstilling og anvendelse
NO20015113L (no) Nye forbindelser, deres fremstilling og anvendelse
NO975711L (no) Nye Dolastatinderivater, deres fremstilling og anvendelse
NO990551D0 (no) Piperidin- og piperazinderivater, og deres anvendelse som muskarine antagonister
NO990012D0 (no) Nye erytromyciner og fremgangsmÕte for deres fremstilling
DK0836615T3 (da) Nye thrombininhibitorer, deres fremstilling og anvendelse
NO20005266L (no) Nye substituerte amider, deres fremstilling og anvendelse
NO952677D0 (no) Nye dihydropyrrolopyridinon- og oksazolopyridinonforbindelser, deres fremstilling og farmasöytiske preparater
NO984717L (no) Nye hydroksamsyre-derivater, deres fremstilling og anvendelse
DK399789A (da) Annellerede tetrahydropyridineddikesyrederivater, deres fremstilling og anvendelse
NO20023146D0 (no) Substituerte fenyl-piperazinderivater, deres fremstilling og anvendelse
NO984714L (no) Nye karboksylsyre-derivater, deres fremstilling og anvendelse
NO984713L (no) Nye karboksylsyre-derivater, deres fremstilling og anvendelse
NO20001934D0 (no) 3-Substituerte tetrahydropyridopyrimidinon-derivater, deres fremstilling og anvendelse
NO954763D0 (no) Piperidinderivater, deres fremstilling og anvendelse
NO984624L (no) Nye furan-diarylmetyliden-derivater, fremgangsmÕte for deres fremstilling og terapeutiske anvendelser derav
NO971424D0 (no) Nye heterocyklisk substituerte imidazolo-kinoksalidoner, deres fremstilling og anvendelse
NO955242D0 (no) Piperidinderivater, fremgangsmåte for fremstilling derav og deres terapeutiske anvendelse
NO981002D0 (no) Karboksylsyrederivater, deres fremstilling og anvendelse
NO20003128D0 (no) Nye p-aminofenylderivater og deres anvendelse
NO20000066D0 (no) 6-pyrrolidin-2-ylpyrindin-derivater, deres fremstilling og deres farmasoeytiske anvendelse
NO965553D0 (no) Nye anidokinoksalin-dioner, deres fremstilling og anvendelse
NO20023188L (no) Nye heteroarylderivater, deres fremstilling og anvendelse
NO982349D0 (no) Nye kinoksalindionderivater, deres fremstilling og anvendelse i legemidler
DK1235809T3 (da) Substituerede 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazociner og deres anvendelse som lægemidler

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application