NO990472D0 - Fluorholdige 1,4-disubstituerte piperidinderivater - Google Patents

Fluorholdige 1,4-disubstituerte piperidinderivater

Info

Publication number
NO990472D0
NO990472D0 NO990472A NO990472A NO990472D0 NO 990472 D0 NO990472 D0 NO 990472D0 NO 990472 A NO990472 A NO 990472A NO 990472 A NO990472 A NO 990472A NO 990472 D0 NO990472 D0 NO 990472D0
Authority
NO
Norway
Prior art keywords
fluorine
piperidine derivatives
disubstituted piperidine
disubstituted
derivatives
Prior art date
Application number
NO990472A
Other languages
English (en)
Norwegian (no)
Other versions
NO990472L (no
Inventor
Yoshimi Tsuchiya
Takashi Nomoto
Hirokazu Ohsawa
Kumiko Kawakami
Kenji Ohwaki
Masaru Nishikibe
Original Assignee
Banyu Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banyu Pharma Co Ltd filed Critical Banyu Pharma Co Ltd
Publication of NO990472L publication Critical patent/NO990472L/no
Publication of NO990472D0 publication Critical patent/NO990472D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/46Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO990472A 1996-08-01 1999-02-01 Fluorholdige 1,4-disubstituerte piperidinderivater NO990472D0 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP21943696 1996-08-01
JP5397997 1997-02-21
PCT/JP1997/002600 WO1998005641A1 (fr) 1996-08-01 1997-07-28 Derives de piperidine fluores a disubstitution en position 1,4

Publications (2)

Publication Number Publication Date
NO990472L NO990472L (no) 1999-02-01
NO990472D0 true NO990472D0 (no) 1999-02-01

Family

ID=26394715

Family Applications (1)

Application Number Title Priority Date Filing Date
NO990472A NO990472D0 (no) 1996-08-01 1999-02-01 Fluorholdige 1,4-disubstituerte piperidinderivater

Country Status (29)

Country Link
US (2) US5948792A (pt)
EP (1) EP0930298B1 (pt)
JP (1) JP3063164B2 (pt)
KR (1) KR20000022214A (pt)
CN (1) CN1226888A (pt)
AR (3) AR008272A1 (pt)
AT (1) ATE229941T1 (pt)
AU (1) AU716050B2 (pt)
BG (1) BG103114A (pt)
BR (1) BR9711108A (pt)
CA (1) CA2261680C (pt)
CO (1) CO4960641A1 (pt)
CZ (1) CZ33199A3 (pt)
DE (1) DE69718026T2 (pt)
EE (1) EE9900038A (pt)
ES (1) ES2188961T3 (pt)
HR (1) HRP970426A2 (pt)
HU (1) HUP9902381A3 (pt)
ID (1) ID17259A (pt)
IL (1) IL127685A0 (pt)
IS (1) IS4960A (pt)
NO (1) NO990472D0 (pt)
NZ (1) NZ333842A (pt)
PE (1) PE92198A1 (pt)
PL (1) PL331431A1 (pt)
SK (1) SK12299A3 (pt)
TR (2) TR199900204T2 (pt)
WO (1) WO1998005641A1 (pt)
YU (1) YU1299A (pt)

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SK8002003A3 (en) 2000-12-22 2004-05-04 Almirall Prodesfarma Ag Quinuclidine carbamate derivatives and their use as M3 antagonists
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CN1558756A (zh) * 2001-09-27 2004-12-29 �ź㴫 用于治疗泌尿疾病的药物组合物
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EP1545508A4 (en) 2002-08-09 2009-11-25 Ranbaxy Lab Ltd 3,6-DISUBSTITUTED AZABICYCLO ¬3.1.0 HEXANE DERIVATIVES AS USEFUL AS MUSCARINIC RECEPTOR AGONISTS
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DE60231341D1 (de) 2002-08-23 2009-04-09 Ranbaxy Lab Ltd Fluor- und sulfonylaminohaltige, 3,6-disubstituierptorantagonisten
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TWI295669B (en) 2002-10-30 2008-04-11 Theravance Inc Substituted 4-amino-1-(pyridylmethyl) piperidine and related compounds
WO2004052857A1 (en) * 2002-12-10 2004-06-24 Ranbaxy Laboratories Limited 3,6-disubstituted azabicyclo [3.1.0] hexane derivatives as muscarinic receptor antagonists
CA2509605C (en) 2002-12-13 2010-10-05 Warner-Lambert Company Llc Alpha-2-delta ligand to treat lower urinary tract symptoms
WO2004056767A1 (en) * 2002-12-23 2004-07-08 Ranbaxy Laboratories Limited 1-substituted-3-pyrrolidine derivatives as muscarinic receptor antagonists
WO2004056811A1 (en) 2002-12-23 2004-07-08 Ranbaxy Laboratories Limited Flavaxate derivatives as muscarinic receptor antagonists
US7488748B2 (en) 2003-01-28 2009-02-10 Ranbaxy Laboratories Limited 3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists
PE20040950A1 (es) 2003-02-14 2005-01-01 Theravance Inc DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
WO2004089898A1 (en) 2003-04-09 2004-10-21 Ranbaxy Laboratories Limited Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists
WO2004089899A1 (en) * 2003-04-10 2004-10-21 Ranbaxy Laboratories Limited Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists
CN100406009C (zh) 2003-04-10 2008-07-30 兰贝克赛实验室有限公司 作为毒蕈碱受体拮抗剂的取代的氮杂双环己烷衍生物
BRPI0409302A (pt) * 2003-04-11 2006-04-11 Ranbaxy Lab Ltd derivados azabiciclo como antagonistas de recetores muscarìnicos, método para sua preparação e composição farmacêutica contendo os mesmos
WO2004091597A2 (en) * 2003-04-15 2004-10-28 Pharmacia & Upjohn Company Llc Method of treating irritable bowel syndrome (ibs)
WO2005007645A1 (en) 2003-07-11 2005-01-27 Theravance, Inc. Substituted 4-amino-1-benzylpiperidine compounds
ATE435855T1 (de) 2003-11-21 2009-07-15 Theravance Inc Verbindungen mit agonistischer wirkung am beta2- adrenergen rezeptor und am muscarinischen rezeptor
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US20100016400A1 (en) * 2004-11-19 2010-01-21 Naresh Kumar Azabicyclic muscarinic receptor antagonists
WO2006064304A1 (en) * 2004-12-15 2006-06-22 Ranbaxy Laboratories Limited Acid addition salts of muscarinic receptor antagonists
US20080319043A1 (en) * 2005-05-03 2008-12-25 Mohammad Salman 3,6-Disubstituted Azabicyclo (3.1.0) Hexane Derivatives as Muscarinic Receptor Antagonists
US7799820B2 (en) * 2005-09-30 2010-09-21 Banyu Pharmaceutical Co., Ltd. 2-Heterocycle-substituted indole derivatives for treating diabetes and associated conditions
EP1934184A1 (en) * 2005-10-05 2008-06-25 Ranbaxy Laboratories, Ltd. 3 -azabicyclooctane derivatives as muscarinic receptor antagonists
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PT2234600E (pt) * 2007-12-21 2014-09-25 Hoffmann La Roche Formulação de anticorpos
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Also Published As

Publication number Publication date
CN1226888A (zh) 1999-08-25
ES2188961T3 (es) 2003-07-01
IS4960A (is) 1999-01-29
EP0930298A4 (en) 2000-06-07
SK12299A3 (en) 2000-05-16
PL331431A1 (en) 1999-07-19
ID17259A (id) 1997-12-11
PE92198A1 (es) 1999-01-09
BR9711108A (pt) 1999-08-17
TR199900204T2 (xx) 2000-01-21
US5948792A (en) 1999-09-07
AR017021A1 (es) 2001-08-22
HUP9902381A3 (en) 2000-06-28
CZ33199A3 (cs) 1999-07-14
HUP9902381A2 (hu) 1999-11-29
AU3635197A (en) 1998-02-25
NO990472L (no) 1999-02-01
CO4960641A1 (es) 2000-09-25
CA2261680A1 (en) 1998-02-12
US6040449A (en) 2000-03-21
TR200001482T2 (tr) 2000-11-21
HRP970426A2 (en) 1998-08-31
EP0930298B1 (en) 2002-12-18
YU1299A (sh) 2002-03-18
IL127685A0 (en) 1999-10-28
JP3063164B2 (ja) 2000-07-12
CA2261680C (en) 2005-03-08
WO1998005641A1 (fr) 1998-02-12
BG103114A (en) 1999-11-30
DE69718026D1 (de) 2003-01-30
NZ333842A (en) 2001-05-25
AR016877A2 (es) 2001-08-01
ATE229941T1 (de) 2003-01-15
AR008272A1 (es) 1999-12-29
EE9900038A (et) 1999-08-16
AU716050B2 (en) 2000-02-17
KR20000022214A (ko) 2000-04-25
EP0930298A1 (en) 1999-07-21
DE69718026T2 (de) 2003-07-10

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