NO990304L - Substituerte triazol-pyridazolderivater som ligander for GABA reseptorer - Google Patents

Substituerte triazol-pyridazolderivater som ligander for GABA reseptorer

Info

Publication number
NO990304L
NO990304L NO990304A NO990304A NO990304L NO 990304 L NO990304 L NO 990304L NO 990304 A NO990304 A NO 990304A NO 990304 A NO990304 A NO 990304A NO 990304 L NO990304 L NO 990304L
Authority
NO
Norway
Prior art keywords
ligands
pyridazole
derivatives
substituted triazole
substituted
Prior art date
Application number
NO990304A
Other languages
English (en)
Norwegian (no)
Other versions
NO990304D0 (no
Inventor
Howard Barff Broughton
William Robert Carling
Jose Luis Castro Pineiro
Alexander Richard Guiblin
Andrew Madin
Kevin William Moore
Michael Geoffrey Russell
Leslie Joseph Street
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9615645.0A external-priority patent/GB9615645D0/en
Priority claimed from GBGB9625397.6A external-priority patent/GB9625397D0/en
Priority claimed from GBGB9714420.8A external-priority patent/GB9714420D0/en
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of NO990304D0 publication Critical patent/NO990304D0/no
Publication of NO990304L publication Critical patent/NO990304L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
NO990304A 1996-07-25 1999-01-22 Substituerte triazol-pyridazolderivater som ligander for GABA reseptorer NO990304L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9615645.0A GB9615645D0 (en) 1996-07-25 1996-07-25 Therapeutic agents
GBGB9625397.6A GB9625397D0 (en) 1996-12-06 1996-12-06 Therapeutic agents
GBGB9714420.8A GB9714420D0 (en) 1997-07-09 1997-07-09 Therapeutic agents
PCT/GB1997/001946 WO1998004559A2 (fr) 1996-07-25 1997-07-17 Derives de triazolo-pyridazine substitues servant de ligands pour recepteurs de gaba

Publications (2)

Publication Number Publication Date
NO990304D0 NO990304D0 (no) 1999-01-22
NO990304L true NO990304L (no) 1999-03-25

Family

ID=27268403

Family Applications (1)

Application Number Title Priority Date Filing Date
NO990304A NO990304L (no) 1996-07-25 1999-01-22 Substituerte triazol-pyridazolderivater som ligander for GABA reseptorer

Country Status (24)

Country Link
US (1) US6255305B1 (fr)
EP (1) EP0915875B1 (fr)
JP (1) JP4216905B2 (fr)
KR (1) KR20000029548A (fr)
CN (1) CN1251589A (fr)
AT (1) ATE236904T1 (fr)
AU (1) AU723098B2 (fr)
BG (1) BG103112A (fr)
BR (1) BR9710729A (fr)
CZ (1) CZ18199A3 (fr)
DE (1) DE69720732T2 (fr)
EA (1) EA002436B1 (fr)
EE (1) EE9900027A (fr)
ES (1) ES2194205T3 (fr)
HU (1) HUP0600527A2 (fr)
IL (1) IL127911A0 (fr)
IS (1) IS4949A (fr)
NO (1) NO990304L (fr)
NZ (1) NZ333768A (fr)
PL (1) PL331072A1 (fr)
SK (1) SK9399A3 (fr)
TR (1) TR199900047T2 (fr)
WO (1) WO1998004559A2 (fr)
YU (1) YU2899A (fr)

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GB9726699D0 (en) * 1997-12-18 1998-02-18 Merck Sharp & Dohme Therapeutic use
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GB9726702D0 (en) * 1997-12-18 1998-02-18 Merck Sharp & Dohme Therapeutic use
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US6110915A (en) * 1997-12-18 2000-08-29 Merck & Co., Inc. Antiemetic use of triazolo-pyridazine derivatives
US6303597B1 (en) 1998-01-14 2001-10-16 Merck Sharp & Dohme Limited Triazolo-pyridazine derivatives as ligands for GABA receptors
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GB9801202D0 (en) * 1998-01-21 1998-03-18 Merck Sharp & Dohme Therapeutic agents
CA2315763A1 (fr) 1998-01-21 1999-07-29 Merck Sharp & Dohme Limited Derives de la triazolo-pyridazine, ligands des recepteurs du gaba
GB9801210D0 (en) * 1998-01-21 1998-03-18 Merck Sharp & Dohme Therapeutic agents
GB9801208D0 (en) 1998-01-21 1998-03-18 Merck Sharp & Dohme Therapeutic agents
GB9801397D0 (en) * 1998-01-22 1998-03-18 Merck Sharp & Dohme Therapeutic agents
GB9801538D0 (en) * 1998-01-23 1998-03-25 Merck Sharp & Dohme Pharmaceutical product
GB9813006D0 (en) * 1998-06-16 1998-08-12 Merck Sharp & Dohme Therapeutic agents
AU755855B2 (en) 1998-06-16 2002-12-19 Merck Sharp & Dohme Limited Triazolo-pyridine derivatives as ligands for GABA receptors
GB9813576D0 (en) * 1998-06-24 1998-08-19 Merck Sharp & Dohme Therapeutic agents
GB9821179D0 (en) * 1998-09-30 1998-11-25 Merck Sharp & Dohme Therapeutic use
CA2346659A1 (fr) * 1998-10-06 2000-04-13 Michiyo Gyoten Composes de pyridazine condenses, leur procede de preparation et leur utilisation
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GB9824897D0 (en) 1998-11-12 1999-01-06 Merck Sharp & Dohme Therapeutic compounds
GB2345443A (en) * 1999-01-08 2000-07-12 Merck Sharp & Dohme Use of triazolo-pyridazines for treating premenstrual syndrome
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GB9903119D0 (en) * 1999-02-11 1999-04-07 Merck Sharp & Dohme Therapeutic agents
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GB9929569D0 (en) 1999-12-14 2000-02-09 Merck Sharp & Dohme Therapeutic agents
GB9929687D0 (en) * 1999-12-15 2000-02-09 Merck Sharp & Dohme Therapeutic agents
GB9929685D0 (en) * 1999-12-15 2000-02-09 Merck Sharp & Dohme Therapeutic agents
GB0000564D0 (en) 2000-01-11 2000-03-01 Merck Sharp & Dohme Therapeutic agents
GB0008696D0 (en) 2000-04-07 2000-05-31 Merck Sharp & Dohme Therapeutic agents
GB0017518D0 (en) * 2000-07-17 2000-08-30 Merck Sharp & Dohme Therapeutic agents
GB0018473D0 (en) 2000-07-27 2000-09-13 Merck Sharp & Dohme Therapeutic agents
GB0028583D0 (en) 2000-11-23 2001-01-10 Merck Sharp & Dohme Therapeutic compounds
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GB0122696D0 (en) * 2001-09-20 2001-11-14 Merck Sharp & Dohme Therapeutic agents
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US20060235021A1 (en) * 2002-08-13 2006-10-19 Wesley Blackaby Phenylpyridazine derivatives as ligands for gaba receptors
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CN107344936B (zh) * 2016-05-06 2022-06-03 上海赛默罗生物科技有限公司 三唑哒嗪类衍生物、其制备方法、药物组合物和用途
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Also Published As

Publication number Publication date
NO990304D0 (no) 1999-01-22
ES2194205T3 (es) 2003-11-16
EE9900027A (et) 1999-08-16
EP0915875B1 (fr) 2003-04-09
HUP0600527A2 (en) 2006-11-28
BG103112A (en) 1999-09-30
EP0915875A2 (fr) 1999-05-19
BR9710729A (pt) 1999-08-17
TR199900047T2 (xx) 1999-03-22
YU2899A (sh) 2000-03-21
CN1251589A (zh) 2000-04-26
AU723098B2 (en) 2000-08-17
IL127911A0 (en) 1999-11-30
JP4216905B2 (ja) 2009-01-28
NZ333768A (en) 2000-09-29
ATE236904T1 (de) 2003-04-15
DE69720732D1 (de) 2003-05-15
CZ18199A3 (cs) 1999-06-16
WO1998004559A2 (fr) 1998-02-05
US6255305B1 (en) 2001-07-03
KR20000029548A (ko) 2000-05-25
PL331072A1 (en) 1999-06-21
SK9399A3 (en) 2000-04-10
EA002436B1 (ru) 2002-04-25
AU3553997A (en) 1998-02-20
DE69720732T2 (de) 2004-01-29
IS4949A (is) 1999-01-19
EA199900164A1 (ru) 2000-04-24
JP2002514169A (ja) 2002-05-14

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