NO984784L - Midler for inhibering av leukocytt-invasjon i vev - Google Patents

Midler for inhibering av leukocytt-invasjon i vev

Info

Publication number
NO984784L
NO984784L NO984784A NO984784A NO984784L NO 984784 L NO984784 L NO 984784L NO 984784 A NO984784 A NO 984784A NO 984784 A NO984784 A NO 984784A NO 984784 L NO984784 L NO 984784L
Authority
NO
Norway
Prior art keywords
atoms
tissues
invasion
inhibiting leukocyte
agent
Prior art date
Application number
NO984784A
Other languages
English (en)
Other versions
NO984784D0 (no
Inventor
Kay Brune
Rupert Hallmann
Original Assignee
Chephasaar Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19616581A external-priority patent/DE19616581C2/de
Application filed by Chephasaar Gmbh filed Critical Chephasaar Gmbh
Publication of NO984784L publication Critical patent/NO984784L/no
Publication of NO984784D0 publication Critical patent/NO984784D0/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pyrrole Compounds (AREA)

Abstract

Et middel for inhibering av leukocytt-invasjon av vev inneholder et hydroksyprolin- derivat med formel (I) der R] og R2 er like eller forskjellige og betyr hydrogen, CMO- alkylgrupper eller C|.8-acylgrupper og R3 betyr en hydroksy-, alkoksy- eller amino- gruppesom kan ha l eller 2 CM-alkylsubstiruenter eller l eller 2 C6.i0-arylsubstituenter. Det beskrives videre et farmasøytisk akseptabelt salt av denne forbindelse, eventuelt med andre brukbare farmasøytiske additiver og/eller hjelpestoffer. Middelet er brukbart for prevensjon og terapi av vevskader forårsaket av invasjon og aktivering av leukocytter.
NO984784A 1996-04-16 1998-10-14 Midler for inhibering av leukocytt-invasjon i vev NO984784D0 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19614919 1996-04-16
DE19616581A DE19616581C2 (de) 1996-04-16 1996-04-25 Verwendung von Oxaceprol zur Behandlung von Reperfusionsschäden
PCT/EP1997/001909 WO1997038690A1 (de) 1996-04-16 1997-04-16 Mittel zur hemmung der leukozyteninvasion in gewebe

Publications (2)

Publication Number Publication Date
NO984784L true NO984784L (no) 1998-10-14
NO984784D0 NO984784D0 (no) 1998-10-14

Family

ID=26024771

Family Applications (1)

Application Number Title Priority Date Filing Date
NO984784A NO984784D0 (no) 1996-04-16 1998-10-14 Midler for inhibering av leukocytt-invasjon i vev

Country Status (8)

Country Link
EP (1) EP0906096B1 (no)
JP (1) JPH11510515A (no)
AT (1) ATE219671T1 (no)
AU (1) AU2698997A (no)
CZ (1) CZ330498A3 (no)
NO (1) NO984784D0 (no)
PL (1) PL329331A1 (no)
WO (1) WO1997038690A1 (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202008018253U1 (de) 2007-02-22 2012-05-21 Beiersdorf Ag Kosmetische und pharmazeutische Anwendungen von N-Acethylhydroxyprolin
CL2008001640A1 (es) * 2007-06-08 2008-11-07 Bergen Teknologioverforing As Uso de hidroxiprolina para preparar una composicion de alemento destinada a promover el crecimiento de un animal, como peces, aves y mamiferos.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932638A (en) * 1967-09-14 1976-01-13 Franco-Chimie S.A.R.L. Compositions and methods for wound healing
DE1795327C3 (de) * 1967-09-14 1979-09-13 S.A.R.L. Franco-Chimie, Paris Verwendung von N-Acetyl-1-Hydroxyprolin
CA1281288C (en) * 1984-11-05 1991-03-12 Wilhelm Hoerrmann Tumor therapy
IT1248669B (it) * 1990-05-30 1995-01-26 Pulitzer Italiana Derivato di idrossiprolina, sua preparazione e composizioni farmaceutiche che lo contengono
JPH05130883A (ja) * 1991-11-13 1993-05-28 Kyowa Hakko Kogyo Co Ltd トランス−ｌ−ヒドロキシプロリンの製造法

Also Published As

Publication number Publication date
WO1997038690A1 (de) 1997-10-23
EP0906096B1 (de) 2002-06-26
EP0906096A1 (de) 1999-04-07
NO984784D0 (no) 1998-10-14
AU2698997A (en) 1997-11-07
JPH11510515A (ja) 1999-09-14
CZ330498A3 (cs) 1999-07-14
ATE219671T1 (de) 2002-07-15
PL329331A1 (en) 1999-03-29

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application