NO983864L - Morfin- og diamorfinsalter av anioniske, ikke-narkotiske analgetika av den substituerte karboksyltypen - Google Patents
Morfin- og diamorfinsalter av anioniske, ikke-narkotiske analgetika av den substituerte karboksyltypenInfo
- Publication number
- NO983864L NO983864L NO983864A NO983864A NO983864L NO 983864 L NO983864 L NO 983864L NO 983864 A NO983864 A NO 983864A NO 983864 A NO983864 A NO 983864A NO 983864 L NO983864 L NO 983864L
- Authority
- NO
- Norway
- Prior art keywords
- morphine
- salts
- anionic
- narcotic analgesics
- substituted carboxyl
- Prior art date
Links
- BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 title abstract 6
- 229960005181 morphine Drugs 0.000 title abstract 3
- GVGLGOZIDCSQPN-PVHGPHFFSA-N Heroin Chemical class O([C@H]1[C@H](C=C[C@H]23)OC(C)=O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4OC(C)=O GVGLGOZIDCSQPN-PVHGPHFFSA-N 0.000 title abstract 2
- 125000000129 anionic group Chemical class 0.000 title abstract 2
- 239000000730 antalgic agent Chemical class 0.000 title abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 3
- TUCNEACPLKLKNU-UHFFFAOYSA-N acetyl Chemical compound C[C]=O TUCNEACPLKLKNU-UHFFFAOYSA-N 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
- C07D489/04—Salts; Organic complexes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19607395A DE19607395C2 (de) | 1996-02-28 | 1996-02-28 | Salze aus einem kationischen narkotischen Analgetikum mit einem anionischen nichtnarkotischen Analgetikum, Verfahren zu deren Herstellung und die diese Salze enthaltenden pharmazeutischen Präparate |
| PCT/EP1997/000711 WO1997031918A1 (de) | 1996-02-28 | 1997-02-15 | Morphin- und diamorphinsalze anionischer nicht-narkotischer analgetika vom typ der substituierten carbonsäuren |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO983864D0 NO983864D0 (no) | 1998-08-21 |
| NO983864L true NO983864L (no) | 1998-08-21 |
Family
ID=7786595
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO983864A NO983864L (no) | 1996-02-28 | 1998-08-21 | Morfin- og diamorfinsalter av anioniske, ikke-narkotiske analgetika av den substituerte karboksyltypen |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6156764A (xx) |
| EP (1) | EP0883619B1 (xx) |
| JP (1) | JP4624497B2 (xx) |
| KR (1) | KR100422276B1 (xx) |
| CN (1) | CN1064363C (xx) |
| AT (1) | ATE212024T1 (xx) |
| AU (1) | AU712255B2 (xx) |
| CZ (1) | CZ294401B6 (xx) |
| DE (2) | DE19607395C2 (xx) |
| DK (1) | DK0883619T3 (xx) |
| ES (1) | ES2171886T3 (xx) |
| HU (1) | HU225268B1 (xx) |
| IL (1) | IL125819A (xx) |
| NO (1) | NO983864L (xx) |
| NZ (1) | NZ331485A (xx) |
| PL (1) | PL185915B1 (xx) |
| PT (1) | PT883619E (xx) |
| SK (1) | SK104398A3 (xx) |
| WO (1) | WO1997031918A1 (xx) |
| ZA (1) | ZA971740B (xx) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001517669A (ja) * | 1997-09-25 | 2001-10-09 | エルティエス ローマン テラピー−ズュステーメ アーゲー | モルヒネアルカロイド類の酸添加塩類およびその応用 |
| EP1709957A3 (en) * | 2001-06-05 | 2007-02-14 | Control Delivery Systems | Sustained-release analgesic compounds |
| EP1448190A2 (en) * | 2001-10-18 | 2004-08-25 | Novartis AG | Salts formed of an at1-receptor antagonist and a cardiovascular agent |
| WO2003043657A1 (en) * | 2001-11-19 | 2003-05-30 | Control Delivery Systems, Inc. | Topical delivery of codrugs |
| EP1465596A1 (en) * | 2002-01-18 | 2004-10-13 | Control Delivery Systems, Inc. | Polymeric gel system for the controlled delivery of codrugs |
| US8557291B2 (en) * | 2002-07-05 | 2013-10-15 | Collegium Pharmaceutical, Inc. | Abuse-deterrent pharmaceutical compositions of opioids and other drugs |
| WO2004004693A1 (en) | 2002-07-05 | 2004-01-15 | Collgegium Pharmaceutical | Abuse-deterrent pharmaceutical compositions of opiods and other drugs |
| US10004729B2 (en) | 2002-07-05 | 2018-06-26 | Collegium Pharmaceutical, Inc. | Tamper-resistant pharmaceutical compositions of opioids and other drugs |
| US8840928B2 (en) | 2002-07-05 | 2014-09-23 | Collegium Pharmaceutical, Inc. | Tamper-resistant pharmaceutical compositions of opioids and other drugs |
| TW200500067A (en) * | 2003-01-21 | 2005-01-01 | Control Delivery Sys Inc | Salts of codrugs and uses related thereto |
| CA2530136C (en) * | 2003-06-26 | 2012-10-16 | Control Delivery Systems, Inc. | In-situ gelling drug delivery system |
| US8815284B2 (en) * | 2003-06-26 | 2014-08-26 | Psivida Us, Inc. | Bioerodible sustained release drug delivery systems |
| WO2005044236A1 (en) * | 2003-10-27 | 2005-05-19 | Control Delivery Systems, Inc. | Suspension delivery system for the sustained and controlled local release of pharmaceuticals |
| LT1765292T (lt) * | 2004-06-12 | 2018-01-10 | Collegium Pharmaceutical, Inc. | Nuo piktnaudžiavimo apsaugotos vaistų formos |
| US10668060B2 (en) | 2009-12-10 | 2020-06-02 | Collegium Pharmaceutical, Inc. | Tamper-resistant pharmaceutical compositions of opioids and other drugs |
| WO2017222575A1 (en) | 2016-06-23 | 2017-12-28 | Collegium Pharmaceutical, Inc. | Process of making more stable abuse-deterrent oral formulations |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4404209A (en) * | 1982-06-30 | 1983-09-13 | E. I. Du Pont De Nemours And Company | Analgesic mixture of nalbuphine and sulindac |
| GB8319546D0 (en) * | 1983-07-20 | 1983-08-24 | Euro Celtique Sa | Pharmaceutical active salts |
| ZA893422B (en) * | 1988-02-24 | 1991-01-30 | Adcock Ingram Lab Ltd | Pharmaceutical composition |
| TW225536B (xx) * | 1990-08-23 | 1994-06-21 | Ciba Geigy Ag | |
| CA2104684A1 (en) * | 1991-03-04 | 1992-09-05 | Mahdi B. Fawzi | Salts/ion pairs of non-steroidal anti-inflammatory drugs in various dosage forms |
| US5256669A (en) * | 1992-08-07 | 1993-10-26 | Aminotek Sciences, Inc. | Methods and compositions for treating acute or chronic pain and drug addiction |
| SE9301057L (sv) * | 1993-03-30 | 1994-10-01 | Pharmacia Ab | Beredning med kontrollerad frisättning |
| FR2708611B1 (fr) * | 1993-07-29 | 1995-10-27 | Meram Lab | Sel de codéine de l'acide 2-(3-benzoylphényl)propionique, procédé d'obtention et compositions pharmaceutiques le contenant. |
| GB9319568D0 (en) * | 1993-09-22 | 1993-11-10 | Euro Celtique Sa | Pharmaceutical compositions and usages |
| US5460826A (en) * | 1994-06-27 | 1995-10-24 | Alza Corporation | Morphine therapy |
-
1996
- 1996-02-28 DE DE19607395A patent/DE19607395C2/de not_active Expired - Fee Related
-
1997
- 1997-02-15 DK DK97903288T patent/DK0883619T3/da active
- 1997-02-15 IL IL12581997A patent/IL125819A/en not_active IP Right Cessation
- 1997-02-15 JP JP53054797A patent/JP4624497B2/ja not_active Expired - Fee Related
- 1997-02-15 AU AU17695/97A patent/AU712255B2/en not_active Ceased
- 1997-02-15 US US09/137,078 patent/US6156764A/en not_active Expired - Fee Related
- 1997-02-15 CZ CZ19982657A patent/CZ294401B6/cs not_active IP Right Cessation
- 1997-02-15 SK SK1043-98A patent/SK104398A3/sk unknown
- 1997-02-15 EP EP97903288A patent/EP0883619B1/de not_active Expired - Lifetime
- 1997-02-15 PT PT97903288T patent/PT883619E/pt unknown
- 1997-02-15 HU HU9900568A patent/HU225268B1/hu not_active IP Right Cessation
- 1997-02-15 AT AT97903288T patent/ATE212024T1/de active
- 1997-02-15 DE DE59706015T patent/DE59706015D1/de not_active Expired - Lifetime
- 1997-02-15 PL PL97328712A patent/PL185915B1/pl not_active IP Right Cessation
- 1997-02-15 KR KR10-1998-0706752A patent/KR100422276B1/ko not_active IP Right Cessation
- 1997-02-15 ES ES97903288T patent/ES2171886T3/es not_active Expired - Lifetime
- 1997-02-15 CN CN97192619A patent/CN1064363C/zh not_active Expired - Fee Related
- 1997-02-15 WO PCT/EP1997/000711 patent/WO1997031918A1/de active IP Right Grant
- 1997-02-15 NZ NZ331485A patent/NZ331485A/xx not_active IP Right Cessation
- 1997-02-27 ZA ZA9701740A patent/ZA971740B/xx unknown
-
1998
- 1998-08-21 NO NO983864A patent/NO983864L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| SK104398A3 (en) | 1998-12-02 |
| AU1769597A (en) | 1997-09-16 |
| US6156764A (en) | 2000-12-05 |
| JP4624497B2 (ja) | 2011-02-02 |
| HUP9900568A2 (hu) | 1999-06-28 |
| CN1064363C (zh) | 2001-04-11 |
| HU225268B1 (en) | 2006-08-28 |
| JP2000505463A (ja) | 2000-05-09 |
| DK0883619T3 (da) | 2002-04-29 |
| ZA971740B (en) | 1997-09-04 |
| CZ265798A3 (cs) | 1998-11-11 |
| PL328712A1 (en) | 1999-02-15 |
| DE19607395A1 (de) | 1997-09-04 |
| ATE212024T1 (de) | 2002-02-15 |
| AU712255B2 (en) | 1999-11-04 |
| WO1997031918A1 (de) | 1997-09-04 |
| CN1212698A (zh) | 1999-03-31 |
| KR19990087343A (ko) | 1999-12-27 |
| PT883619E (pt) | 2002-07-31 |
| IL125819A (en) | 2002-04-21 |
| IL125819A0 (en) | 1999-04-11 |
| NO983864D0 (no) | 1998-08-21 |
| DE19607395C2 (de) | 2002-11-21 |
| DE59706015D1 (de) | 2002-02-21 |
| EP0883619A1 (de) | 1998-12-16 |
| NZ331485A (en) | 1999-03-29 |
| HUP9900568A3 (en) | 2001-08-28 |
| PL185915B1 (pl) | 2003-08-29 |
| CZ294401B6 (cs) | 2004-12-15 |
| KR100422276B1 (ko) | 2004-07-30 |
| ES2171886T3 (es) | 2002-09-16 |
| EP0883619B1 (de) | 2002-01-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |