NO980414L - Benzimidazolforbindelser - Google Patents
BenzimidazolforbindelserInfo
- Publication number
- NO980414L NO980414L NO980414A NO980414A NO980414L NO 980414 L NO980414 L NO 980414L NO 980414 A NO980414 A NO 980414A NO 980414 A NO980414 A NO 980414A NO 980414 L NO980414 L NO 980414L
- Authority
- NO
- Norway
- Prior art keywords
- benzimidazole
- Prior art date
Links
- HYZJCKYKOHLVJF-UHFFFAOYSA-N 1H-benzimidazole Chemical compound C1=CC=C2NC=NC2=C1 HYZJCKYKOHLVJF-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/10—Radicals substituted by halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/14—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/16—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Data Exchanges In Wide-Area Networks (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9515843.2A GB9515843D0 (en) | 1995-08-02 | 1995-08-02 | Benzimidazole compounds |
GBGB9611245.3A GB9611245D0 (en) | 1996-05-30 | 1996-05-30 | Benzimidazole compounds |
PCT/GB1996/001832 WO1997004771A1 (en) | 1995-08-02 | 1996-07-30 | Benzimidazole compounds |
Publications (3)
Publication Number | Publication Date |
---|---|
NO980414D0 NO980414D0 (no) | 1998-01-30 |
NO980414L true NO980414L (no) | 1998-04-02 |
NO317033B1 NO317033B1 (no) | 2004-07-26 |
Family
ID=26307504
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19980414A NO317033B1 (no) | 1995-08-02 | 1998-01-30 | Anvendelse av en benzimidazolforbindelse til fremstilling av et medisinsk eller veterinaermedisinsk preparat, benzimidazolforbindelser og fremgangsmate for fremstilling derav, samt farmasoytiske formuleringer og preparater |
Country Status (26)
Country | Link |
---|---|
US (2) | US6100283A (no) |
EP (1) | EP0841924B1 (no) |
JP (1) | JPH11510154A (no) |
KR (1) | KR100447539B1 (no) |
CN (1) | CN1159007C (no) |
AP (1) | AP866A (no) |
AT (1) | ATE225173T1 (no) |
AU (1) | AU714873B2 (no) |
BR (1) | BR9610051A (no) |
CA (1) | CA2225465A1 (no) |
CZ (1) | CZ30398A3 (no) |
DE (1) | DE69624115T2 (no) |
DK (1) | DK0841924T3 (no) |
EA (1) | EA000999B1 (no) |
ES (1) | ES2183004T3 (no) |
HU (1) | HUP9901092A3 (no) |
IL (1) | IL123147A (no) |
MX (1) | MX9800927A (no) |
NO (1) | NO317033B1 (no) |
NZ (1) | NZ313713A (no) |
OA (1) | OA10661A (no) |
PL (1) | PL324869A1 (no) |
PT (1) | PT841924E (no) |
SK (1) | SK13598A3 (no) |
TR (1) | TR199800127T1 (no) |
WO (1) | WO1997004771A1 (no) |
Families Citing this family (75)
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FR2776291B1 (fr) * | 1998-03-18 | 2000-06-16 | Pf Medicament | Nouveaux derives bis-benzamides, leur procede de fabrication, les compositions pharmaceutiques les contenant et leur utilisation comme medicament |
US6919366B2 (en) * | 1998-05-22 | 2005-07-19 | Avanir Pharmaceuticals | Benzimidazole derivatives as modulators of IgE |
US6911462B2 (en) * | 1998-05-22 | 2005-06-28 | Avanir Pharmaceuticals | Benzimidazole compounds for regulating IgE |
UA65635C2 (uk) | 1998-09-03 | 2004-04-15 | Н-Гене Кутато Кфт. | НЕНАСИЧЕНІ ПОХІДНІ ГІДРОКСИМОВОЇ КИСЛОТИ, ЩО МАЮТЬ ВЛАСТИВОСТІ ІНГІБІТОРІВ NAD<sup>+</sup>-ADP-РИБОЗИЛТРАНСФЕРАЗИ |
BR9915013A (pt) | 1998-11-03 | 2001-08-07 | Basf Ag | Composto, uso dos mesmos, processo para preparar os mesmos, droga, e, método para detecção in vitro para inibidores parp |
BR9915381A (pt) * | 1998-11-17 | 2001-08-14 | Basf Ag | Uso de um composto, e, composto |
DE19916460B4 (de) * | 1999-04-12 | 2006-12-21 | Abbott Gmbh & Co. Kg | Substituierte Benzimidazole, deren Herstellung und Anwendung |
HUP0200749A3 (en) | 1998-11-27 | 2003-03-28 | Basf Ag | Substituted benzimidazoles and their use as parp inhibitors and process for their preparation |
PT1140936E (pt) * | 1999-01-11 | 2004-06-30 | Agouron Pharma | Inibidores triciclicos de poli(adp-ribose) polimerases |
FR2788518B1 (fr) * | 1999-01-14 | 2001-03-02 | Centre Nat Rech Scient | Nouveaux carbamates actives stables, leur procede de preparation et leur utilisation pour la preparation d'urees |
DE19918211A1 (de) | 1999-04-22 | 2000-10-26 | Basf Ag | Cycloalkylsubstituierte Benzimidazole, deren Herstellung und Anwendung |
DE19920936A1 (de) * | 1999-05-07 | 2000-11-09 | Basf Ag | Heterozyklisch substituierte Benzimidazole, deren Herstellung und Anwendung |
ECSP003637A (es) * | 1999-08-31 | 2002-03-25 | Agouron Pharma | Inhibidores triciclicos de poli (adp-ribosa) polimerasas |
AU7314200A (en) * | 1999-09-17 | 2001-04-24 | Yamanouchi Pharmaceutical Co., Ltd. | Benzimidazole derivatives |
DE19946289A1 (de) * | 1999-09-28 | 2001-03-29 | Basf Ag | Benzodiazepin-Derivate, deren Herstellung und Anwendung |
US6759425B2 (en) | 1999-10-21 | 2004-07-06 | Avanir Pharmaceuticals | Benzimidazole compounds for modulating IgE and inhibiting cellular proliferation |
IT1315267B1 (it) * | 1999-12-23 | 2003-02-03 | Novuspharma Spa | Derivati di 2-(1h-indol-3-il)-2-oxo-acetammidi ad attivita'antitumorale |
DE50112961D1 (de) * | 2000-02-01 | 2007-10-18 | Abbott Gmbh & Co Kg | Heterozyklische verbindungen und deren anwendung als parp-inhibitoren |
DE10021468A1 (de) * | 2000-05-04 | 2001-11-08 | Basf Ag | Verwendung von PARP-Inhibitoren in kosmetischen Zubereitungen |
DE10022925A1 (de) * | 2000-05-11 | 2001-11-15 | Basf Ag | Substituierte Indole als PARP-Inhibitoren |
ATE369853T1 (de) * | 2001-03-12 | 2007-09-15 | Avanir Pharmaceuticals | Benzimidazolderivate zur ige-modulierung und zellproliferationshemmung |
US7072771B2 (en) * | 2001-06-07 | 2006-07-04 | University Of Kentucky Research Foundation | Selective PARP-1 targeting for designing chemo/radio sensitizing agents |
AU2002334355A1 (en) * | 2001-09-06 | 2003-03-18 | Prochon Biotech Ltd. | Protein tyrosine kinase inhibitors |
DE10201240A1 (de) * | 2002-01-15 | 2003-07-24 | Bayer Ag | Substituierte Alkyluracile und ihre Verwendung |
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US20040034078A1 (en) * | 2002-06-14 | 2004-02-19 | Agouron Pharmaceuticals, Inc. | Benzimidazole inhibitors of poly(ADP-ribosyl) polymerase |
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AU2003270426A1 (en) | 2002-09-12 | 2004-04-30 | Avanir Pharmaceuticals | PHENYL-INDOLE COMPOUNDS FOR MODULATING IgE AND INHIBITING CELLULAR PROLIFERATION |
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GB1087561A (en) * | 1963-02-16 | 1967-10-18 | Fisons Pest Control Ltd | Fluorinated benzimidazoles and compositions containing them |
DE3346575A1 (de) * | 1983-12-23 | 1985-07-04 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue benzimidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel |
DE3522230A1 (de) * | 1985-06-21 | 1987-01-02 | Thomae Gmbh Dr K | Neue 2-arylimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
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GB8904174D0 (en) * | 1989-02-23 | 1989-04-05 | British Bio Technology | Compounds |
IE70593B1 (en) * | 1989-09-29 | 1996-12-11 | Eisai Co Ltd | Biphenylmethane derivative the use of it and pharmacological compositions containing same |
IL95975A (en) * | 1989-10-24 | 1997-06-10 | Takeda Chemical Industries Ltd | N-benzyl- 2-alkylbenzimidazole derivatives, their production and pharmaceutical compositions containing them |
CA2093125C (en) * | 1990-10-02 | 2003-12-16 | Warner-Lambert Company | Angiotensin ii antagonists |
US5216003A (en) * | 1992-01-02 | 1993-06-01 | G. D. Searle & Co. | Diacid-containing benzimidazole compounds for treatment of neurotoxic injury |
AU675484B2 (en) * | 1993-03-24 | 1997-02-06 | Neurosearch A/S | Benzimidazole compounds, their use and preparation |
US5824696A (en) * | 1993-09-01 | 1998-10-20 | Smithkline Beecham Corporation | Medicaments |
US5735973A (en) * | 1993-12-20 | 1998-04-07 | Tamura Kaken Corporation | Printed circuit board surface protective agent |
US5821258A (en) * | 1994-12-27 | 1998-10-13 | Mitsui Chemicals, Inc. | Phenylbenzimidazole derivatives |
-
1996
- 1996-07-30 DK DK96925875T patent/DK0841924T3/da active
- 1996-07-30 EP EP96925875A patent/EP0841924B1/en not_active Expired - Lifetime
- 1996-07-30 PL PL96324869A patent/PL324869A1/xx unknown
- 1996-07-30 CA CA002225465A patent/CA2225465A1/en not_active Abandoned
- 1996-07-30 AU AU66240/96A patent/AU714873B2/en not_active Ceased
- 1996-07-30 PT PT96925875T patent/PT841924E/pt unknown
- 1996-07-30 BR BR9610051-6A patent/BR9610051A/pt not_active Application Discontinuation
- 1996-07-30 EA EA199800184A patent/EA000999B1/ru not_active IP Right Cessation
- 1996-07-30 CZ CZ98303A patent/CZ30398A3/cs unknown
- 1996-07-30 DE DE69624115T patent/DE69624115T2/de not_active Expired - Fee Related
- 1996-07-30 ES ES96925875T patent/ES2183004T3/es not_active Expired - Lifetime
- 1996-07-30 NZ NZ313713A patent/NZ313713A/en unknown
- 1996-07-30 IL IL12314796A patent/IL123147A/en not_active IP Right Cessation
- 1996-07-30 WO PCT/GB1996/001832 patent/WO1997004771A1/en not_active Application Discontinuation
- 1996-07-30 JP JP9507360A patent/JPH11510154A/ja not_active Ceased
- 1996-07-30 HU HU9901092A patent/HUP9901092A3/hu not_active Application Discontinuation
- 1996-07-30 AT AT96925875T patent/ATE225173T1/de not_active IP Right Cessation
- 1996-07-30 TR TR1998/00127T patent/TR199800127T1/xx unknown
- 1996-07-30 KR KR10-1998-0700752A patent/KR100447539B1/ko not_active IP Right Cessation
- 1996-07-30 SK SK135-98A patent/SK13598A3/sk unknown
- 1996-07-30 AP APAP/P/1998/001183A patent/AP866A/en active
- 1996-07-31 CN CNB961968818A patent/CN1159007C/zh not_active Expired - Fee Related
-
1998
- 1998-01-30 OA OA9800017A patent/OA10661A/en unknown
- 1998-01-30 NO NO19980414A patent/NO317033B1/no not_active IP Right Cessation
- 1998-02-02 US US09/017,314 patent/US6100283A/en not_active Expired - Fee Related
- 1998-02-02 MX MX9800927A patent/MX9800927A/es not_active IP Right Cessation
-
2000
- 2000-06-16 US US09/594,776 patent/US6310082B1/en not_active Expired - Fee Related
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