NO975987L - 4-Fenylaminotiazol-derivater, fremgangsmåte for fremstilling av disse og farmasöytiske blandinger inneholdende nevnte derivater - Google Patents
4-Fenylaminotiazol-derivater, fremgangsmåte for fremstilling av disse og farmasöytiske blandinger inneholdende nevnte derivaterInfo
- Publication number
- NO975987L NO975987L NO975987A NO975987A NO975987L NO 975987 L NO975987 L NO 975987L NO 975987 A NO975987 A NO 975987A NO 975987 A NO975987 A NO 975987A NO 975987 L NO975987 L NO 975987L
- Authority
- NO
- Norway
- Prior art keywords
- alkyl
- group
- radical
- cycloalkyl
- moiety
- Prior art date
Links
- HIKWKZYGQPNLIA-UHFFFAOYSA-N n-phenyl-1,3-thiazol-4-amine Chemical class C=1C=CC=CC=1NC1=CSC=N1 HIKWKZYGQPNLIA-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 9
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 2
- 125000006527 (C1-C5) alkyl group Chemical group 0.000 abstract 1
- RAIPHJJURHTUIC-UHFFFAOYSA-N 1,3-thiazol-2-amine Chemical class NC1=NC=CS1 RAIPHJJURHTUIC-UHFFFAOYSA-N 0.000 abstract 1
- 125000003341 7 membered heterocyclic group Chemical group 0.000 abstract 1
- 229910003827 NRaRb Inorganic materials 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9507437A FR2735777B1 (fr) | 1995-06-21 | 1995-06-21 | Derives de 4-phenylaminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant |
| PCT/FR1996/000941 WO1997000868A1 (fr) | 1995-06-21 | 1996-06-18 | Derives de 4-phenylaminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO975987D0 NO975987D0 (no) | 1997-12-19 |
| NO975987L true NO975987L (no) | 1998-02-19 |
Family
ID=9480235
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO975987A NO975987L (no) | 1995-06-21 | 1997-12-19 | 4-Fenylaminotiazol-derivater, fremgangsmåte for fremstilling av disse og farmasöytiske blandinger inneholdende nevnte derivater |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5880135A (cs) |
| EP (1) | EP0833822A1 (cs) |
| JP (1) | JP3067807B2 (cs) |
| KR (1) | KR19990028325A (cs) |
| AU (1) | AU710300B2 (cs) |
| BR (1) | BR9609420A (cs) |
| CA (1) | CA2222266A1 (cs) |
| CZ (1) | CZ410397A3 (cs) |
| EE (1) | EE9700333A (cs) |
| FR (1) | FR2735777B1 (cs) |
| HU (1) | HUP9900056A2 (cs) |
| IL (1) | IL122293A0 (cs) |
| IS (1) | IS4635A (cs) |
| NO (1) | NO975987L (cs) |
| NZ (1) | NZ312157A (cs) |
| PL (1) | PL324202A1 (cs) |
| RU (1) | RU2146253C1 (cs) |
| SK (1) | SK171197A3 (cs) |
| TR (1) | TR199701654T1 (cs) |
| TW (1) | TW416952B (cs) |
| WO (1) | WO1997000868A1 (cs) |
| ZA (1) | ZA965294B (cs) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7094782B1 (en) | 1996-07-24 | 2006-08-22 | Bristol-Myers Squibb Company | Azolo triazines and pyrimidines |
| US6191131B1 (en) | 1997-07-23 | 2001-02-20 | Dupont Pharmaceuticals Company | Azolo triazines and pyrimidines |
| US6313124B1 (en) | 1997-07-23 | 2001-11-06 | Dupont Pharmaceuticals Company | Tetrazine bicyclic compounds |
| US6060478A (en) * | 1996-07-24 | 2000-05-09 | Dupont Pharmaceuticals | Azolo triazines and pyrimidines |
| US6124289A (en) * | 1996-07-24 | 2000-09-26 | Dupont Pharmaceuticals Co. | Azolo triazines and pyrimidines |
| FR2754258B1 (fr) | 1996-10-08 | 1998-12-31 | Sanofi Sa | Derives d'aminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant |
| US6187777B1 (en) * | 1998-02-06 | 2001-02-13 | Amgen Inc. | Compounds and methods which modulate feeding behavior and related diseases |
| US6531475B1 (en) | 1998-11-12 | 2003-03-11 | Neurocrine Biosciences, Inc. | CRF receptor antagonists and methods relating thereto |
| NZ511267A (en) | 1998-11-12 | 2002-12-20 | Neurocrine Biosciences Inc | Tricyclic heterocyclic CRF receptor antagonists and their use in treatment |
| CN1217945C (zh) | 1998-11-12 | 2005-09-07 | 纽罗克里恩生物科学有限公司 | Crf受体拮抗剂以及与其有关的方法 |
| FR2796380B3 (fr) * | 1999-07-15 | 2001-08-17 | Sanofi Synthelabo | Nouveaux derives d'aminothiazoles, leur preparation et les compositions pharmaceutiques les contenant |
| FR2819508B1 (fr) * | 2001-01-12 | 2005-01-21 | Sod Conseils Rech Applic | Derives de 2-arylimino-2, 3-dihydorthiazoles, leurs procedes de preparation et leur utilisation therapeutiques |
| US6432989B1 (en) * | 1999-08-27 | 2002-08-13 | Pfizer Inc | Use of CRF antagonists to treat circadian rhythm disorders |
| CO5271670A1 (es) | 1999-10-29 | 2003-04-30 | Pfizer Prod Inc | Antagonistas del factor de liberacion de corticitropina y composiciones relacionadas |
| AU2001234180A1 (en) * | 2000-02-25 | 2001-09-03 | Japan Tobacco Inc. | Benzamide derivative and use thereof |
| EP1149583A3 (en) * | 2000-04-13 | 2001-11-14 | Pfizer Products Inc. | Combinations of corticotropin releasing factor antagonists and growth hormone secretagogues |
| DE10045650A1 (de) * | 2000-09-15 | 2002-03-28 | Adolf Wuerth Gmbh & Co Kg | Kunststoffdübel |
| US7205320B2 (en) | 2001-01-22 | 2007-04-17 | Memory Pharmaceuticals Corp. | Phosphodiesterase 4 inhibitors |
| US7153871B2 (en) | 2001-01-22 | 2006-12-26 | Memory Pharmaceuticals Corporation | Phosphodiesterase 4 inhibitors, including aminoindazole and aminobenzofuran analogs |
| WO2003015777A1 (en) * | 2001-08-13 | 2003-02-27 | Lion Bioscience Ag | Nr1h4 nuclear receptor binding compounds |
| AU2002240733B2 (en) * | 2001-10-18 | 2009-04-09 | Zlatko Ademovic | Additive cytoprotective effects of two bioactive regions of pro-opiomelanocortin hormone |
| HRP20050083A2 (en) | 2002-07-19 | 2005-08-31 | Memory Pharmaceuticals Corporation | Phosphodiesterase 4 inhibitors, including n-substituted aniline and diphenylamine analogs |
| EP1549619B1 (en) * | 2002-07-19 | 2009-01-21 | Memory Pharmaceutical Corporation | 4-aminobenzofuran compounds as phosphodiesterase 4 inhibitors |
| US7087625B2 (en) | 2002-11-19 | 2006-08-08 | Memory Pharmaceuticals Corporation | Phosphodiesterase 4 inhibitors |
| US20090048255A1 (en) * | 2003-07-21 | 2009-02-19 | Schumacher Richard A | Phosphodiesterase 4 inhibitors, including n-substituted aniline and diphenylamine analogs |
| MY141255A (en) * | 2003-12-11 | 2010-03-31 | Memory Pharm Corp | Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs |
| WO2007084391A2 (en) * | 2006-01-18 | 2007-07-26 | Amgen Inc. | Thiazole compounds as protein kinase b ( pkb) inhibitors |
| US8252333B2 (en) | 2006-01-26 | 2012-08-28 | Jorge Cueto-Garcia | Biodegradable, non-toxic biological adhesive for use in abdominal surgery |
| US20100029689A1 (en) * | 2008-07-02 | 2010-02-04 | Memory Pharmaceuticals Corporation | Phosphodiesterase 4 inhibitors |
| WO2015166370A1 (en) | 2014-04-28 | 2015-11-05 | Pfizer Inc. | Heteroaromatic compounds and their use as dopamine d1 ligands |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2612187B1 (fr) * | 1987-03-12 | 1989-07-21 | Sanofi Sa | Derives du thiazole actifs sur le systeme cholinergique, leur procede de preparation et compositions pharmaceutiques en contenant |
| GB8724566D0 (en) * | 1987-10-20 | 1987-11-25 | Roussel Lab Ltd | Chemical compounds |
| FR2656610B1 (fr) * | 1989-12-29 | 1992-05-07 | Sanofi Sa | Derives d'amino-2 phenyl-4 thiazole, leur procede de preparation et leur application therapeutique. |
| FR2692893B1 (fr) * | 1992-06-24 | 1994-09-02 | Sanofi Elf | Dérivés alkylamino ramifiés du thiazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent. |
-
1995
- 1995-06-21 FR FR9507437A patent/FR2735777B1/fr not_active Expired - Lifetime
-
1996
- 1996-06-18 RU RU98100764A patent/RU2146253C1/ru active
- 1996-06-18 IL IL12229396A patent/IL122293A0/xx unknown
- 1996-06-18 HU HU9900056A patent/HUP9900056A2/hu unknown
- 1996-06-18 PL PL96324202A patent/PL324202A1/xx unknown
- 1996-06-18 US US08/945,098 patent/US5880135A/en not_active Expired - Fee Related
- 1996-06-18 TR TR97/01654T patent/TR199701654T1/xx unknown
- 1996-06-18 EE EE9700333A patent/EE9700333A/xx unknown
- 1996-06-18 CA CA002222266A patent/CA2222266A1/fr not_active Abandoned
- 1996-06-18 EP EP96922946A patent/EP0833822A1/fr not_active Withdrawn
- 1996-06-18 BR BR9609420A patent/BR9609420A/pt not_active Application Discontinuation
- 1996-06-18 KR KR1019970709640A patent/KR19990028325A/ko not_active Abandoned
- 1996-06-18 CZ CZ974103A patent/CZ410397A3/cs unknown
- 1996-06-18 NZ NZ312157A patent/NZ312157A/en unknown
- 1996-06-18 AU AU63627/96A patent/AU710300B2/en not_active Ceased
- 1996-06-18 JP JP9503616A patent/JP3067807B2/ja not_active Expired - Lifetime
- 1996-06-18 WO PCT/FR1996/000941 patent/WO1997000868A1/fr not_active Application Discontinuation
- 1996-06-18 SK SK1711-97A patent/SK171197A3/sk unknown
- 1996-06-21 ZA ZA9605294A patent/ZA965294B/xx unknown
- 1996-07-17 TW TW085107427A patent/TW416952B/zh active
-
1997
- 1997-12-16 IS IS4635A patent/IS4635A/is unknown
- 1997-12-19 NO NO975987A patent/NO975987L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU710300B2 (en) | 1999-09-16 |
| CA2222266A1 (fr) | 1997-01-09 |
| FR2735777A1 (fr) | 1996-12-27 |
| KR19990028325A (ko) | 1999-04-15 |
| WO1997000868A1 (fr) | 1997-01-09 |
| BR9609420A (pt) | 1999-05-18 |
| JPH10511693A (ja) | 1998-11-10 |
| FR2735777B1 (fr) | 1997-09-12 |
| RU2146253C1 (ru) | 2000-03-10 |
| TW416952B (en) | 2001-01-01 |
| HUP9900056A2 (hu) | 1999-05-28 |
| JP3067807B2 (ja) | 2000-07-24 |
| NZ312157A (en) | 1999-04-29 |
| ZA965294B (en) | 1997-12-22 |
| IS4635A (is) | 1997-12-16 |
| AU6362796A (en) | 1997-01-22 |
| EE9700333A (et) | 1998-06-15 |
| IL122293A0 (en) | 1998-04-05 |
| EP0833822A1 (fr) | 1998-04-08 |
| MX9710378A (es) | 1998-07-31 |
| PL324202A1 (en) | 1998-05-11 |
| US5880135A (en) | 1999-03-09 |
| CZ410397A3 (cs) | 1998-04-15 |
| NO975987D0 (no) | 1997-12-19 |
| TR199701654T1 (xx) | 1998-05-21 |
| SK171197A3 (en) | 1998-08-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |